JP2020500010A - 分泌性バリアント免疫調節タンパク質および改変細胞療法 - Google Patents

分泌性バリアント免疫調節タンパク質および改変細胞療法 Download PDF

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JP2020500010A
JP2020500010A JP2019520983A JP2019520983A JP2020500010A JP 2020500010 A JP2020500010 A JP 2020500010A JP 2019520983 A JP2019520983 A JP 2019520983A JP 2019520983 A JP2019520983 A JP 2019520983A JP 2020500010 A JP2020500010 A JP 2020500010A
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JP2020500010A5 (enExample
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ライアン スワンソン
ライアン スワンソン
マイケル コルナッカー
マイケル コルナッカー
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アルパイン イミューン サイエンシズ インコーポレイテッド
アルパイン イミューン サイエンシズ インコーポレイテッド
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JP2019520983A 2016-10-20 2017-10-20 分泌性バリアント免疫調節タンパク質および改変細胞療法 Pending JP2020500010A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662410827P 2016-10-20 2016-10-20
US62/410,827 2016-10-20
US201762475210P 2017-03-22 2017-03-22
US62/475,210 2017-03-22
US201762537921P 2017-07-27 2017-07-27
US62/537,921 2017-07-27
PCT/US2017/057743 WO2018075978A1 (en) 2016-10-20 2017-10-20 Secretable variant immunomodulatory proteins and engineered cell therapy

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JP2020500010A true JP2020500010A (ja) 2020-01-09
JP2020500010A5 JP2020500010A5 (enExample) 2020-11-26

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US (1) US20200040059A1 (enExample)
EP (2) EP3872180A1 (enExample)
JP (1) JP2020500010A (enExample)
KR (1) KR20190099194A (enExample)
CN (1) CN110352245A (enExample)
AU (1) AU2017345764A1 (enExample)
CA (1) CA3040296A1 (enExample)
IL (1) IL266045A (enExample)
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Cited By (2)

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JP2024501286A (ja) * 2020-12-23 2024-01-11 リジェネロン・ファーマシューティカルズ・インコーポレイテッド アンカー改変型抗体をコードする核酸およびその使用
JP2024164118A (ja) * 2018-09-19 2024-11-26 アルパイン イミューン サイエンシズ インコーポレイテッド バリアントｃｄ８０融合タンパク質および関連構築物の方法および使用

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BR122018004815A2 (pt) 2015-04-30 2019-09-10 Psioxus Therapeutics Ltd adenovírus oncolítico que codifica proteína b7
MA43163A (fr) 2015-11-02 2018-09-12 Five Prime Therapeutics Inc Polypeptides à domaine extracellulaire cd80 et leur utilisation dans le traitement du cancer
EA201891022A1 (ru) 2015-12-17 2019-01-31 Псайоксус Терапьютикс Лимитед Вирус, кодирующий антитело к комплексу tcr или фрагмент указанного антитела
US11325948B2 (en) 2016-03-19 2022-05-10 Exuma Biotech Corp. Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL
US11111505B2 (en) 2016-03-19 2021-09-07 Exuma Biotech, Corp. Methods and compositions for transducing lymphocytes and regulating the activity thereof
WO2021042072A1 (en) * 2019-09-01 2021-03-04 Exuma Biotech Corp. Methods and compositions for the modification and delivery of lymphocytes
KR102824067B1 (ko) 2016-04-15 2025-06-23 알파인 이뮨 사이언시즈, 인코포레이티드 Icos 리간드 변이체 면역조절 단백질 및 그의 용도
EP3443000B1 (en) 2016-04-15 2025-11-12 Alpine Immune Sciences, Inc. Cd80 variant immunomodulatory proteins and uses thereof
US11471488B2 (en) 2016-07-28 2022-10-18 Alpine Immune Sciences, Inc. CD155 variant immunomodulatory proteins and uses thereof
US11834490B2 (en) 2016-07-28 2023-12-05 Alpine Immune Sciences, Inc. CD112 variant immunomodulatory proteins and uses thereof
GB201713765D0 (en) 2017-08-28 2017-10-11 Psioxus Therapeutics Ltd Modified adenovirus
CN119614520A (zh) 2016-08-29 2025-03-14 阿卡米斯生物公司 携带双特异性t细胞衔接器的腺病毒
CA3054068A1 (en) * 2017-03-16 2018-09-20 Alpine Immune Sciences, Inc. Cd80 variant immunomodulatory proteins and uses thereof
CN110809581A (zh) 2017-03-16 2020-02-18 高山免疫科学股份有限公司 Pd-l2变体免疫调节蛋白及其用途
JP2020517913A (ja) 2017-04-28 2020-06-18 ファイブ プライム セラピューティクス， インコーポレイテッド Ｃｄ８０細胞外ドメインポリペプチドによる治療方法
WO2018220207A1 (en) 2017-06-01 2018-12-06 Psioxus Therapeutics Limited Oncolytic virus and method
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