JP2020189856A5 - - Google Patents
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- Publication number
- JP2020189856A5 JP2020189856A5 JP2020133620A JP2020133620A JP2020189856A5 JP 2020189856 A5 JP2020189856 A5 JP 2020189856A5 JP 2020133620 A JP2020133620 A JP 2020133620A JP 2020133620 A JP2020133620 A JP 2020133620A JP 2020189856 A5 JP2020189856 A5 JP 2020189856A5
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- JP
- Japan
- Prior art keywords
- compound
- crystalline form
- content
- represented
- less
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 150000001875 compounds Chemical class 0.000 claims 46
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims 9
- 238000000034 method Methods 0.000 claims 9
- 238000004519 manufacturing process Methods 0.000 claims 6
- 238000002156 mixing Methods 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 239000002904 solvent Substances 0.000 claims 6
- 239000000725 suspension Substances 0.000 claims 6
- 239000003937 drug carrier Substances 0.000 claims 4
- 238000001914 filtration Methods 0.000 claims 4
- 230000002265 prevention Effects 0.000 claims 4
- 230000036617 axillary hyperhidrosis Effects 0.000 claims 3
- 238000002360 preparation method Methods 0.000 claims 3
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 claims 2
- 208000008454 Hyperhidrosis Diseases 0.000 claims 2
- BZLVMXJERCGZMT-UHFFFAOYSA-N Methyl tert-butyl ether Chemical compound COC(C)(C)C BZLVMXJERCGZMT-UHFFFAOYSA-N 0.000 claims 2
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 claims 2
- 229960004373 acetylcholine Drugs 0.000 claims 2
- PQJJJMRNHATNKG-UHFFFAOYSA-N ethyl bromoacetate Chemical compound CCOC(=O)CBr PQJJJMRNHATNKG-UHFFFAOYSA-N 0.000 claims 2
- 230000037315 hyperhidrosis Effects 0.000 claims 2
- 239000012535 impurity Substances 0.000 claims 2
- 238000003756 stirring Methods 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 1
- 230000006806 disease prevention Effects 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 208000005589 hyperhidrosis palmaris ET plantaris Diseases 0.000 claims 1
- 230000037392 palmar hyperhidrosis Effects 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962851880P | 2019-05-23 | 2019-05-23 | |
| US62/851,880 | 2019-05-23 | ||
| JP2020089283A JP6748329B1 (ja) | 2019-05-23 | 2020-05-22 | ソフピロニウム臭化物の結晶形態及びその製造方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020089283A Division JP6748329B1 (ja) | 2019-05-23 | 2020-05-22 | ソフピロニウム臭化物の結晶形態及びその製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020189856A JP2020189856A (ja) | 2020-11-26 |
| JP2020189856A5 true JP2020189856A5 (https=) | 2023-05-08 |
| JP7605598B2 JP7605598B2 (ja) | 2024-12-24 |
Family
ID=72146250
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020089283A Active JP6748329B1 (ja) | 2019-05-23 | 2020-05-22 | ソフピロニウム臭化物の結晶形態及びその製造方法 |
| JP2020133620A Active JP7605598B2 (ja) | 2019-05-23 | 2020-08-06 | ソフピロニウム臭化物の結晶形態及びその製造方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020089283A Active JP6748329B1 (ja) | 2019-05-23 | 2020-05-22 | ソフピロニウム臭化物の結晶形態及びその製造方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US20220298108A1 (https=) |
| EP (1) | EP3972955A4 (https=) |
| JP (2) | JP6748329B1 (https=) |
| KR (1) | KR20220011671A (https=) |
| CN (1) | CN114008023B (https=) |
| AU (1) | AU2020277881B2 (https=) |
| BR (1) | BR112021023241A2 (https=) |
| CA (1) | CA3139948A1 (https=) |
| CL (1) | CL2021003047A1 (https=) |
| CO (1) | CO2021017456A2 (https=) |
| IL (1) | IL288285B1 (https=) |
| MX (1) | MX2021014163A (https=) |
| MY (1) | MY206154A (https=) |
| PH (1) | PH12021552915A1 (https=) |
| SG (1) | SG11202111678WA (https=) |
| TW (2) | TWI838531B (https=) |
| WO (1) | WO2020235665A1 (https=) |
| ZA (1) | ZA202109514B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220298108A1 (en) * | 2019-05-23 | 2022-09-22 | Kaken Pharmaceutical Co., Ltd. | Crystalline form of sofpironium bromide and preparation method thereof |
| EP4213158A1 (en) | 2020-11-13 | 2023-07-19 | Ahead Biocomputing, Co. Ltd | Information processing device, information processing method, recording medium recording information processing program, and information processing system |
| CN115925603B (zh) * | 2022-11-29 | 2025-07-22 | 山东齐都药业有限公司 | 索吡溴铵的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7927613B2 (en) * | 2002-02-15 | 2011-04-19 | University Of South Florida | Pharmaceutical co-crystal compositions |
| US7417147B2 (en) * | 2005-11-10 | 2008-08-26 | Bodor Nicholas S | Soft anticholinergic zwitterions |
| ATE529399T1 (de) * | 2005-11-10 | 2011-11-15 | Nicholas S Bodor | Sanfte anticholinerge ester |
| MX357741B (es) * | 2012-07-06 | 2018-07-23 | Laboratorios Senosiain S A De C V Star | Nuevas formas sólidas de inhibidores de fosfodiesterasa tipo 5. |
| US9512166B2 (en) * | 2012-09-05 | 2016-12-06 | Amri Ssci, Llc | Cocrystals of progesterone |
| US20150259283A1 (en) * | 2014-03-13 | 2015-09-17 | Brickell Biotech, Inc. | Formulation for soft anticholinergic analogs |
| US10282282B2 (en) * | 2016-06-29 | 2019-05-07 | Synopsys, Inc. | Automated HTTP user flows simulator |
| EP3494106B1 (en) * | 2016-08-02 | 2022-07-20 | Journey Medical Corporation | Processes for making, and methods of using, glycopyrronium compounds |
| US20220298108A1 (en) * | 2019-05-23 | 2022-09-22 | Kaken Pharmaceutical Co., Ltd. | Crystalline form of sofpironium bromide and preparation method thereof |
-
2020
- 2020-05-22 US US17/611,158 patent/US20220298108A1/en active Pending
- 2020-05-22 KR KR1020217041385A patent/KR20220011671A/ko not_active Ceased
- 2020-05-22 CA CA3139948A patent/CA3139948A1/en active Pending
- 2020-05-22 BR BR112021023241A patent/BR112021023241A2/pt unknown
- 2020-05-22 EP EP20809754.3A patent/EP3972955A4/en active Pending
- 2020-05-22 SG SG11202111678WA patent/SG11202111678WA/en unknown
- 2020-05-22 MY MYPI2021006212A patent/MY206154A/en unknown
- 2020-05-22 TW TW109117164A patent/TWI838531B/zh active
- 2020-05-22 MX MX2021014163A patent/MX2021014163A/es unknown
- 2020-05-22 AU AU2020277881A patent/AU2020277881B2/en active Active
- 2020-05-22 CN CN202080034880.8A patent/CN114008023B/zh active Active
- 2020-05-22 TW TW112144978A patent/TWI870116B/zh active
- 2020-05-22 WO PCT/JP2020/020210 patent/WO2020235665A1/en not_active Ceased
- 2020-05-22 IL IL288285A patent/IL288285B1/en unknown
- 2020-05-22 JP JP2020089283A patent/JP6748329B1/ja active Active
- 2020-08-06 JP JP2020133620A patent/JP7605598B2/ja active Active
- 2020-11-25 US US17/105,376 patent/US11566000B2/en active Active
- 2020-11-26 PH PH1/2021/552915A patent/PH12021552915A1/en unknown
-
2021
- 2021-06-30 US US17/364,445 patent/US11584715B2/en active Active
- 2021-11-18 CL CL2021003047A patent/CL2021003047A1/es unknown
- 2021-11-24 ZA ZA2021/09514A patent/ZA202109514B/en unknown
- 2021-12-20 CO CONC2021/0017456A patent/CO2021017456A2/es unknown
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