JP2020090464A5 - - Google Patents
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- Publication number
- JP2020090464A5 JP2020090464A5 JP2018229293A JP2018229293A JP2020090464A5 JP 2020090464 A5 JP2020090464 A5 JP 2020090464A5 JP 2018229293 A JP2018229293 A JP 2018229293A JP 2018229293 A JP2018229293 A JP 2018229293A JP 2020090464 A5 JP2020090464 A5 JP 2020090464A5
- Authority
- JP
- Japan
- Prior art keywords
- tablet according
- tablet
- hydrogen phosphate
- calcium hydrogen
- anhydrous calcium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 claims 6
- 235000019700 dicalcium phosphate Nutrition 0.000 claims 6
- WSVLPVUVIUVCRA-KPKNDVKVSA-N Alpha-lactose monohydrate Chemical compound O.O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O WSVLPVUVIUVCRA-KPKNDVKVSA-N 0.000 claims 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 2
- 239000011230 binding agent Substances 0.000 claims 2
- 239000007884 disintegrant Substances 0.000 claims 2
- GBBSUAFBMRNDJC-INIZCTEOSA-N eszopiclone Chemical compound C1CN(C)CCN1C(=O)O[C@H]1C2=NC=CN=C2C(=O)N1C1=CC=C(Cl)C=N1 GBBSUAFBMRNDJC-INIZCTEOSA-N 0.000 claims 2
- 229960001578 eszopiclone Drugs 0.000 claims 2
- 239000000314 lubricant Substances 0.000 claims 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical group [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- GBBSUAFBMRNDJC-MRXNPFEDSA-N (5R)-zopiclone Chemical compound C1CN(C)CCN1C(=O)O[C@@H]1C2=NC=CN=C2C(=O)N1C1=CC=C(Cl)C=N1 GBBSUAFBMRNDJC-MRXNPFEDSA-N 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 1
- 229920002261 Corn starch Polymers 0.000 claims 1
- FFEARJCKVFRZRR-UHFFFAOYSA-N L-Methionine Natural products CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 claims 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 1
- 229930195722 L-methionine Natural products 0.000 claims 1
- 229920000881 Modified starch Polymers 0.000 claims 1
- MHQJUHSHQGQVTM-HNENSFHCSA-N Octadecyl fumarate Chemical compound CCCCCCCCCCCCCCCCCCOC(=O)\C=C/C(O)=O MHQJUHSHQGQVTM-HNENSFHCSA-N 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- VJHCJDRQFCCTHL-UHFFFAOYSA-N acetic acid 2,3,4,5,6-pentahydroxyhexanal Chemical compound CC(O)=O.OCC(O)C(O)C(O)C(O)C=O VJHCJDRQFCCTHL-UHFFFAOYSA-N 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- CJZGTCYPCWQAJB-UHFFFAOYSA-L calcium stearate Chemical compound [Ca+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CJZGTCYPCWQAJB-UHFFFAOYSA-L 0.000 claims 1
- 235000013539 calcium stearate Nutrition 0.000 claims 1
- 239000008116 calcium stearate Substances 0.000 claims 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 1
- 229950008138 carmellose Drugs 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 239000008120 corn starch Substances 0.000 claims 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 235000019359 magnesium stearate Nutrition 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 229960004452 methionine Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000003287 optical effect Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 229920003109 sodium starch glycolate Polymers 0.000 claims 1
- 229940079832 sodium starch glycolate Drugs 0.000 claims 1
- 239000008109 sodium starch glycolate Substances 0.000 claims 1
- 229940071138 stearyl fumarate Drugs 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- -1 sucrose fatty acid ester Chemical class 0.000 claims 1
- 238000005550 wet granulation Methods 0.000 claims 1
- 229940100445 wheat starch Drugs 0.000 claims 1
- 229960000820 zopiclone Drugs 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018229293A JP7304691B2 (ja) | 2018-12-06 | 2018-12-06 | ゾピクロン、その光学異性体又はこれらの塩の何れかを有効成分として含有する錠剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018229293A JP7304691B2 (ja) | 2018-12-06 | 2018-12-06 | ゾピクロン、その光学異性体又はこれらの塩の何れかを有効成分として含有する錠剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020090464A JP2020090464A (ja) | 2020-06-11 |
| JP2020090464A5 true JP2020090464A5 (enrdf_load_stackoverflow) | 2022-01-11 |
| JP7304691B2 JP7304691B2 (ja) | 2023-07-07 |
Family
ID=71012377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018229293A Active JP7304691B2 (ja) | 2018-12-06 | 2018-12-06 | ゾピクロン、その光学異性体又はこれらの塩の何れかを有効成分として含有する錠剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP7304691B2 (enrdf_load_stackoverflow) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4849186B2 (ja) | 2009-10-28 | 2012-01-11 | Ｊｆｅスチール株式会社 | 熱間プレス部材およびその製造方法 |
| JP7572798B2 (ja) * | 2019-06-06 | 2024-10-24 | キョーリンリメディオ株式会社 | エスゾピクロン含有錠 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05221863A (ja) * | 1991-08-09 | 1993-08-31 | Taisho Pharmaceut Co Ltd | 安定化方法 |
| GB9401894D0 (en) * | 1994-02-01 | 1994-03-30 | Rhone Poulenc Rorer Ltd | New compositions of matter |
| JP2011241148A (ja) * | 2008-09-08 | 2011-12-01 | Nippon Chemiphar Co Ltd | 医療用固形製剤 |
| WO2010116385A2 (en) * | 2009-04-08 | 2010-10-14 | Rubicon Research Private Limited | Pharmaceutical compositions for alleviating unpleasant taste |
| JP2015205852A (ja) * | 2014-04-22 | 2015-11-19 | 協和化学工業株式会社 | 球状の無水リン酸水素カルシウムを用いた崩壊性に優れた錠剤、および球状の無水リン酸水素カルシウムを賦形剤として用いた崩壊性に優れた錠剤 |
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2018
- 2018-12-06 JP JP2018229293A patent/JP7304691B2/ja active Active