JP2019537559A5 - - Google Patents
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- Publication number
- JP2019537559A5 JP2019537559A5 JP2019517991A JP2019517991A JP2019537559A5 JP 2019537559 A5 JP2019537559 A5 JP 2019537559A5 JP 2019517991 A JP2019517991 A JP 2019517991A JP 2019517991 A JP2019517991 A JP 2019517991A JP 2019537559 A5 JP2019537559 A5 JP 2019537559A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- nrr
- formula
- pyridin
- imidazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662403660P | 2016-10-03 | 2016-10-03 | |
| US62/403,660 | 2016-10-03 | ||
| PCT/US2017/054668 WO2018067422A1 (en) | 2016-10-03 | 2017-09-30 | Novel jak1 selective inhibitors and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019537559A JP2019537559A (ja) | 2019-12-26 |
| JP2019537559A5 true JP2019537559A5 (cg-RX-API-DMAC7.html) | 2021-03-04 |
| JP7089141B2 JP7089141B2 (ja) | 2022-06-22 |
Family
ID=61831161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019517991A Active JP7089141B2 (ja) | 2016-10-03 | 2017-09-30 | 新規なｊａｋ１選択的阻害剤およびその使用 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US10738060B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3509591B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP7089141B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102399848B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN108366994B (cg-RX-API-DMAC7.html) |
| AU (3) | AU2017339417C1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK3509591T3 (cg-RX-API-DMAC7.html) |
| EA (1) | EA201990523A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2901216T3 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1253040A1 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20211965T1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE058120T2 (cg-RX-API-DMAC7.html) |
| IL (3) | IL265358B (cg-RX-API-DMAC7.html) |
| MX (1) | MX390005B (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ751284A (cg-RX-API-DMAC7.html) |
| PL (1) | PL3509591T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT3509591T (cg-RX-API-DMAC7.html) |
| RS (1) | RS62695B1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018067422A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS62695B1 (sr) | 2016-10-03 | 2022-01-31 | Highlightll Pharmaceutical Hainan Co Ltd | Novi jak1 selektivni inhibitori i njihove upotrebe |
| PL3568396T3 (pl) | 2017-01-11 | 2021-05-31 | Leo Pharma A/S | Nowe pochodne aminoimidazopirydyny jako inhibitory kinaz janusowych i ich zastosowanie farmaceutyczne |
| EA202191170A1 (ru) * | 2018-10-31 | 2021-07-27 | Инсайт Корпорейшн | Комбинированная терапия для лечения гематологических заболеваний |
| IL285999B1 (en) * | 2019-03-05 | 2025-09-01 | Incyte Corp | JAK1 inhibitor pathway for the treatment of chronic lung allograft dysfunction |
| TW202102222A (zh) * | 2019-03-19 | 2021-01-16 | 美商英塞特公司 | 白斑病之生物標記物 |
| BR112021024530A2 (pt) | 2019-06-06 | 2022-01-18 | Highlightll Pharmaceutical Hainan Co Ltd | Método para sintetizar composto de furoimidazopiridina, substância polimórfica e substância polimórfica de sal |
| KR20240100424A (ko) | 2019-06-06 | 2024-07-01 | 항저우 하이라이트엘엘 파마슈티컬 씨오., 엘티디. | 푸로이미다조피리딘 화합물의 합성 방법, 푸로이미다조피리딘 화합물의 결정 형태, 및 그의 염의 결정 형태 |
| BR112022023550A2 (pt) | 2020-05-19 | 2023-01-03 | Bayer Cropscience Ag | (tio)amidas azabicíclicas como compostos fungicidas |
| CN116057056B (zh) | 2020-06-10 | 2025-09-19 | 拜耳公司 | 作为杀真菌剂的氮杂双环取代的杂环化合物 |
| WO2022260945A1 (en) * | 2021-06-07 | 2022-12-15 | The Regents Of The University Of California | Compositions and methods for treating celiac disease |
| CN118059096A (zh) * | 2021-09-13 | 2024-05-24 | 杭州高光制药有限公司 | 治疗cns病症的方法 |
| CN114213424B (zh) | 2021-12-30 | 2023-05-26 | 杭州高光制药有限公司 | 一种呋喃[3，2-b]并吡啶衍生物的合成方法 |
| WO2025224600A1 (en) * | 2024-04-21 | 2025-10-30 | Biohaven Therapeutics Ltd. | Treatment of alpha-synucleinopathies and neuroprotection |
| WO2025248468A1 (en) | 2024-05-28 | 2025-12-04 | Biohaven Therapeutics Ltd. | Use of tyk2/jak1 inhibitors to treat amyloid-related imaging abnormalities (aria) |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4369172A (en) | 1981-12-18 | 1983-01-18 | Forest Laboratories Inc. | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
| EP0188040B1 (en) | 1985-01-11 | 1991-08-14 | Abbott Laboratories Limited | Slow release solid preparation |
| JP2773959B2 (ja) | 1990-07-10 | 1998-07-09 | 信越化学工業株式会社 | 大腸内放出性固形製剤 |
| UA73092C2 (uk) | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Таблетка з ентеросолюбільним покриттям і спосіб її приготування |
| ATE292961T1 (de) | 1998-07-28 | 2005-04-15 | Tanabe Seiyaku Co | Zur wirkstoffabgabe an zielorten im darm fähige zubereitung |
| JP2000119271A (ja) | 1998-08-12 | 2000-04-25 | Hokuriku Seiyaku Co Ltd | １ｈ―イミダゾピリジン誘導体 |
| US6461631B1 (en) | 1999-11-16 | 2002-10-08 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| US6800663B2 (en) | 2002-10-18 | 2004-10-05 | Alkermes Controlled Therapeutics Inc. Ii, | Crosslinked hydrogel copolymers |
| JP2007526324A (ja) | 2004-03-02 | 2007-09-13 | スミスクライン・ビーチャム・コーポレイション | Ａｋｔ活性のある阻害剤 |
| CN101277965A (zh) * | 2005-08-04 | 2008-10-01 | 西特里斯药业公司 | 作为SIRTUIN调节化合物的咪唑并[2,1-b]噻唑衍生物 |
| CN102741253A (zh) * | 2009-09-29 | 2012-10-17 | 艾科睿控股公司 | PI3K(δ)选择性抑制剂 |
| WO2012022045A1 (en) * | 2010-08-20 | 2012-02-23 | Hutchison Medipharma Limited | Pyrrolopyrimidine compounds and uses thereof |
| PH12013500661A1 (en) * | 2010-10-08 | 2017-08-23 | Abbvie Inc | FURO[3,2-d]PYRIMIDINE COMPOUNDS |
| WO2013007768A1 (en) | 2011-07-13 | 2013-01-17 | F. Hoffmann-La Roche Ag | Tricyclic heterocyclic compounds, compositions and methods of use thereof as jak inhibitors |
| PH12013502670A1 (en) | 2011-08-12 | 2016-07-29 | Nissan Chemical Ind Ltd | Tricyclic heterocyclic compounds and jak inhibitors |
| AR093308A1 (es) | 2012-11-01 | 2015-05-27 | Incyte Corp | Derivados triciclicos fusionados de tiofeno como inhibidores de jak |
| CA2926361A1 (en) | 2013-10-24 | 2015-04-30 | Abbvie Inc. | Jak1 selective inhibitor and uses thereof |
| PE20170300A1 (es) | 2014-04-30 | 2017-04-19 | Incyte Corp | Procesos para preparar un inhibidor de jak 1 y nuevas formas de este |
| WO2015184305A1 (en) | 2014-05-30 | 2015-12-03 | Incyte Corporation | TREATMENT OF CHRONIC NEUTROPHILIC LEUKEMIA (CNL) AND ATYPICAL CHRONIC MYELOID LEUKEMIA (aCML) BY INHIBITORS OF JAK1 |
| RS62695B1 (sr) | 2016-10-03 | 2022-01-31 | Highlightll Pharmaceutical Hainan Co Ltd | Novi jak1 selektivni inhibitori i njihove upotrebe |
-
2017
- 2017-09-30 RS RS20211521A patent/RS62695B1/sr unknown
- 2017-09-30 JP JP2019517991A patent/JP7089141B2/ja active Active
- 2017-09-30 MX MX2019003649A patent/MX390005B/es unknown
- 2017-09-30 HU HUE17858944A patent/HUE058120T2/hu unknown
- 2017-09-30 NZ NZ751284A patent/NZ751284A/en unknown
- 2017-09-30 PT PT178589446T patent/PT3509591T/pt unknown
- 2017-09-30 EA EA201990523A patent/EA201990523A1/ru unknown
- 2017-09-30 PL PL17858944T patent/PL3509591T3/pl unknown
- 2017-09-30 KR KR1020197009016A patent/KR102399848B1/ko active Active
- 2017-09-30 CN CN201780004442.5A patent/CN108366994B/zh active Active
- 2017-09-30 ES ES17858944T patent/ES2901216T3/es active Active
- 2017-09-30 HK HK18112420.5A patent/HK1253040A1/zh unknown
- 2017-09-30 US US16/333,994 patent/US10738060B2/en not_active Ceased
- 2017-09-30 DK DK17858944.6T patent/DK3509591T3/da active
- 2017-09-30 HR HRP20211965TT patent/HRP20211965T1/hr unknown
- 2017-09-30 WO PCT/US2017/054668 patent/WO2018067422A1/en not_active Ceased
- 2017-09-30 AU AU2017339417A patent/AU2017339417C1/en active Active
- 2017-09-30 CN CN202110514751.5A patent/CN113214278B/zh active Active
- 2017-09-30 US US17/526,799 patent/USRE49834E1/en active Active
- 2017-09-30 EP EP17858944.6A patent/EP3509591B1/en active Active
-
2019
- 2019-03-13 IL IL265358A patent/IL265358B/en unknown
-
2022
- 2022-02-17 AU AU2022201058A patent/AU2022201058B2/en active Active
- 2022-02-17 AU AU2022201061A patent/AU2022201061B2/en active Active
- 2022-03-10 IL IL291265A patent/IL291265B2/en unknown
- 2022-03-10 IL IL291267A patent/IL291267B2/en unknown
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