JP2019537446A5 - - Google Patents

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Publication number
JP2019537446A5
JP2019537446A5 JP2019524226A JP2019524226A JP2019537446A5 JP 2019537446 A5 JP2019537446 A5 JP 2019537446A5 JP 2019524226 A JP2019524226 A JP 2019524226A JP 2019524226 A JP2019524226 A JP 2019524226A JP 2019537446 A5 JP2019537446 A5 JP 2019537446A5
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JP
Japan
Prior art keywords
nucleic acid
sequence
composition
pharmaceutical composition
domain
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JP2019524226A
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English (en)
Japanese (ja)
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JP2019537446A (ja
JP7338937B2 (ja
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Priority claimed from PCT/KR2017/010897 external-priority patent/WO2018088694A2/ko
Publication of JP2019537446A publication Critical patent/JP2019537446A/ja
Publication of JP2019537446A5 publication Critical patent/JP2019537446A5/ja
Application granted granted Critical
Publication of JP7338937B2 publication Critical patent/JP7338937B2/ja
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JP2019524226A 2016-11-14 2017-09-28 人工的に操作されたsc機能制御システム Active JP7338937B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662421516P 2016-11-14 2016-11-14
US62/421,516 2016-11-14
PCT/KR2017/010897 WO2018088694A2 (ko) 2016-11-14 2017-09-28 인위적으로 조작된 sc 기능 조절 시스템

Publications (3)

Publication Number Publication Date
JP2019537446A JP2019537446A (ja) 2019-12-26
JP2019537446A5 true JP2019537446A5 (enExample) 2020-11-12
JP7338937B2 JP7338937B2 (ja) 2023-09-05

Family

ID=62109586

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019524226A Active JP7338937B2 (ja) 2016-11-14 2017-09-28 人工的に操作されたsc機能制御システム

Country Status (9)

Country Link
US (1) US12331086B2 (enExample)
EP (2) EP3539980A4 (enExample)
JP (1) JP7338937B2 (enExample)
KR (2) KR102437228B1 (enExample)
CN (1) CN110248957B (enExample)
AU (1) AU2017358122B2 (enExample)
BR (1) BR112019009725A2 (enExample)
RU (2) RU2768043C2 (enExample)
WO (1) WO2018088694A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2022103641A (ru) * 2017-09-28 2022-03-18 Тулджен Инкорпорейтед Искусственная модификация генома для регуляции экспрессии гена
US11572574B2 (en) 2017-09-28 2023-02-07 Toolgen Incorporated Artificial genome manipulation for gene expression regulation
JP7410154B2 (ja) * 2018-09-12 2024-01-09 インスティチュート フォー ベーシック サイエンス 遺伝的に変異された細胞の死滅誘導組成物及び該組成物を用いた遺伝的に変異された細胞の死滅誘導方法
EP3798301A1 (en) * 2019-09-25 2021-03-31 KWS SAAT SE & Co. KGaA Promoter repression
WO2021184021A1 (en) * 2020-03-13 2021-09-16 Codiak Biosciences, Inc. Extracellular vesicle-aso constructs targeting pmp22
CN114621922A (zh) * 2022-02-15 2022-06-14 中山大学附属第五医院 一种大鼠海绵体神经来源施旺细胞的提取纯化和培养方法
WO2025079278A1 (ja) * 2023-10-10 2025-04-17 国立大学法人 東京医科歯科大学 シャルコー・マリー・トゥース病の処置剤

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100613038B1 (ko) * 2004-07-07 2006-08-16 공주대학교 산학협력단 염색체 17p11.2-p12 지역의 중복을 제외한 유전자돌연변이를 발병 원인으로 하는 CMT 질환의 진단방법및 진단키트
US8124749B2 (en) * 2007-06-12 2012-02-28 Case Western Reserve University Targeted cell death
EP2912175B1 (en) 2012-10-23 2018-08-22 Toolgen Incorporated Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof
WO2014093622A2 (en) 2012-12-12 2014-06-19 The Broad Institute, Inc. Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
EP3674411A1 (en) * 2013-06-17 2020-07-01 The Broad Institute, Inc. Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation
WO2015048577A2 (en) * 2013-09-27 2015-04-02 Editas Medicine, Inc. Crispr-related methods and compositions
EP3090044B1 (en) * 2013-12-26 2021-11-03 The General Hospital Corporation Multiplex guide rnas
EP3152319A4 (en) * 2014-06-05 2017-12-27 Sangamo BioSciences, Inc. Methods and compositions for nuclease design
WO2016021973A1 (ko) 2014-08-06 2016-02-11 주식회사 툴젠 캄필로박터 제주니 crispr/cas 시스템 유래 rgen을 이용한 유전체 교정
EP4434589A3 (en) 2015-10-23 2025-05-14 President and Fellows of Harvard College Evolved cas9 proteins for gene editing

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