JP2019536818A5 - - Google Patents

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Publication number
JP2019536818A5
JP2019536818A5 JP2019548783A JP2019548783A JP2019536818A5 JP 2019536818 A5 JP2019536818 A5 JP 2019536818A5 JP 2019548783 A JP2019548783 A JP 2019548783A JP 2019548783 A JP2019548783 A JP 2019548783A JP 2019536818 A5 JP2019536818 A5 JP 2019536818A5
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JP
Japan
Prior art keywords
myopathy
muscle
disease
loss
atrophy
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Application number
JP2019548783A
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English (en)
Japanese (ja)
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JP2019536818A (ja
JP7683901B2 (ja
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Priority claimed from GBGB1620119.6A external-priority patent/GB201620119D0/en
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Publication of JP2019536818A publication Critical patent/JP2019536818A/ja
Publication of JP2019536818A5 publication Critical patent/JP2019536818A5/ja
Priority to JP2023083666A priority Critical patent/JP2023116479A/ja
Application granted granted Critical
Publication of JP7683901B2 publication Critical patent/JP7683901B2/ja
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JP2019548783A 2016-11-29 2017-11-28 筋肉性能改善化合物 Active JP7683901B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023083666A JP2023116479A (ja) 2016-11-29 2023-05-22 筋肉性能改善化合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1620119.6 2016-11-29
GBGB1620119.6A GB201620119D0 (en) 2016-11-29 2016-11-29 Compounds
PCT/IB2017/057436 WO2018100483A1 (en) 2016-11-29 2017-11-28 Muscle performance improvement compounds

Related Child Applications (1)

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JP2023083666A Division JP2023116479A (ja) 2016-11-29 2023-05-22 筋肉性能改善化合物

Publications (3)

Publication Number Publication Date
JP2019536818A JP2019536818A (ja) 2019-12-19
JP2019536818A5 true JP2019536818A5 (https=) 2021-01-14
JP7683901B2 JP7683901B2 (ja) 2025-05-27

Family

ID=58073474

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019548783A Active JP7683901B2 (ja) 2016-11-29 2017-11-28 筋肉性能改善化合物
JP2023083666A Pending JP2023116479A (ja) 2016-11-29 2023-05-22 筋肉性能改善化合物

Family Applications After (1)

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JP2023083666A Pending JP2023116479A (ja) 2016-11-29 2023-05-22 筋肉性能改善化合物

Country Status (11)

Country Link
US (1) US11407799B2 (https=)
EP (1) EP3548509A1 (https=)
JP (2) JP7683901B2 (https=)
KR (1) KR102622245B1 (https=)
CN (1) CN110036024B (https=)
AU (1) AU2017367277B2 (https=)
CA (1) CA3045245A1 (https=)
GB (1) GB201620119D0 (https=)
NZ (1) NZ754625A (https=)
WO (1) WO2018100483A1 (https=)
ZA (1) ZA201903261B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110430890B (zh) 2016-11-10 2024-09-10 科乐斯疗法公司 激活素受体iia型变体及其使用方法
EP3706777B1 (en) 2017-11-09 2024-05-22 Keros Therapeutics, Inc. Activin receptor type iia variants and methods of use thereof
IL320014A (en) 2018-01-12 2025-06-01 Keros Therapeutics Inc Activin receptor type iib variants and methods of use thereof
JP7405772B2 (ja) 2018-05-09 2023-12-26 ケロス セラピューティクス インコーポレイテッド アクチビンiia型受容体変異体および同変異体を含む医薬組成物
JP2023512423A (ja) * 2019-12-24 2023-03-27 ジュベナ・セラピューティクス・インコーポレイテッド 再生性ポリペプチドおよびその使用
WO2021189006A1 (en) * 2020-03-20 2021-09-23 Keros Therapeutics, Inc. Methods of using activin receptor type iia variants
WO2021189010A1 (en) 2020-03-20 2021-09-23 Keros Therapeutics, Inc. Methods of using activin receptor type iib variants
IL296394A (en) 2020-03-20 2022-11-01 Keros Therapeutics Inc Type ii activin receptor chimeras and methods of using them
CN116171147A (zh) * 2020-07-24 2023-05-26 新加坡科技研究局 伤口愈合组合物及其用途
JP2024511315A (ja) * 2021-03-10 2024-03-13 アクセルロン ファーマ インコーポレイテッド Actrii-alk4アンタゴニスト及び心不全の治療方法
US20250064952A1 (en) * 2021-03-10 2025-02-27 Acceleron Pharma Inc. Actrii-alk4 antagonists and methods of treating heart failure
KR20240029031A (ko) 2021-06-21 2024-03-05 쥬베나 테라퓨틱스, 인크. 재생 폴리펩티드 및 이의 용도

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69434934D1 (de) * 1993-10-14 2007-04-12 Harvard College Verfahren zur induzierung und zur erhaltung neuronalen zellen
US20040223966A1 (en) 2002-10-25 2004-11-11 Wolfman Neil M. ActRIIB fusion polypeptides and uses therefor
US7355018B2 (en) 2003-09-30 2008-04-08 Regeneron Pharmaceuticals, Inc. Modified IGF1 polypeptides with increased stability and potency
US20060216279A1 (en) 2005-03-22 2006-09-28 Glass David J Myostatin inhibiting fusion polypeptides and therapeutic methods thereof
US20100004171A1 (en) 2006-08-08 2010-01-07 Bazan Nicolas G Therapeutic Methods for Neuropathic Pain
CA2661836A1 (en) 2006-09-05 2008-03-13 Eli Lilly And Company Anti-myostatin antibodies
ES2756725T3 (es) 2007-02-09 2020-04-27 Acceleron Pharma Inc Composiciones farmacéuticas que comprenden antagonistas de Activina-ActRIIA
JP5766179B2 (ja) 2009-04-27 2015-08-19 ノバルティス アーゲー 筋肉増殖を増加させるための組成物および方法
EP2440577A4 (en) 2009-06-12 2013-01-23 Acceleron Pharma Inc SHORTEN ACTRIIB FC FUSION PROTEINS
US9676845B2 (en) * 2009-06-16 2017-06-13 Hoffmann-La Roche, Inc. Bispecific antigen binding proteins
EP2295068A1 (en) * 2009-09-04 2011-03-16 Neurotune AG Modified agrin-fragment capable of restoring muscle strength for use as a medicament
JP6267425B2 (ja) * 2009-11-17 2018-01-24 アクセルロン ファーマ, インコーポレイテッド 筋ジストロフィー治療のためのユートロフィン誘導に関するactriibタンパク質およびその改変体およびその使用

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