JP2019536479A5 - - Google Patents

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Publication number
JP2019536479A5
JP2019536479A5 JP2019547195A JP2019547195A JP2019536479A5 JP 2019536479 A5 JP2019536479 A5 JP 2019536479A5 JP 2019547195 A JP2019547195 A JP 2019547195A JP 2019547195 A JP2019547195 A JP 2019547195A JP 2019536479 A5 JP2019536479 A5 JP 2019536479A5
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JP
Japan
Prior art keywords
enzyme
cytochrome
hydroxylated
compound
cells
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JP2019547195A
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English (en)
Japanese (ja)
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JP2019536479A (ja
JP7142813B2 (ja
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Priority claimed from PCT/GB2017/053432 external-priority patent/WO2018091885A1/en
Publication of JP2019536479A publication Critical patent/JP2019536479A/ja
Publication of JP2019536479A5 publication Critical patent/JP2019536479A5/ja
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Publication of JP7142813B2 publication Critical patent/JP7142813B2/ja
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JP2019547195A 2016-11-15 2017-11-15 アミコラトプシス・ルリダ由来シトクロムｐ４５０を用いた分岐状脂肪族または芳香族基質のヒドロキシ化法 Active JP7142813B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB201619344 2016-11-15
GB1619344.3 2016-11-15
PCT/GB2017/053432 WO2018091885A1 (en) 2016-11-15 2017-11-15 Hydroxylation of branched aliphatic or aromatic substrates employing the amycolatopsis lurida cytochrome p450

Publications (3)

Publication Number Publication Date
JP2019536479A JP2019536479A (ja) 2019-12-19
JP2019536479A5 true JP2019536479A5 (enExample) 2020-12-24
JP7142813B2 JP7142813B2 (ja) 2022-09-28

Family

ID=60421812

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019547195A Active JP7142813B2 (ja) 2016-11-15 2017-11-15 アミコラトプシス・ルリダ由来シトクロムｐ４５０を用いた分岐状脂肪族または芳香族基質のヒドロキシ化法

Country Status (4)

Country Link
US (1) US11384371B2 (enExample)
EP (1) EP3541949A1 (enExample)
JP (1) JP7142813B2 (enExample)
WO (1) WO2018091885A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201807815D0 (en) * 2018-05-14 2018-06-27 Hypha Discovery Ltd Hydroxylation techniques
GB201819209D0 (en) 2018-11-26 2019-01-09 Hypha Discovery Ltd Biocatalytic techniques
GB201917077D0 (en) 2019-11-22 2020-01-08 Hypha Discovery Ltd Biocatalytic techniques
CN113072504B (zh) * 2021-03-29 2022-11-22 四川摩尔生物制药有限公司 一种波生坦代谢物的化学合成方法
GB202107512D0 (en) 2021-05-26 2021-07-07 Hypha Discovery Ltd Cytochrome P450 enzyme

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002357872A1 (en) 2001-12-26 2003-07-24 Bristol-Myers Squibb Company Compositions and methods for hydroxylating epothilones
US6884608B2 (en) * 2001-12-26 2005-04-26 Bristol-Myers Squibb Company Compositions and methods for hydroxylating epothilones
WO2004078978A1 (en) 2003-02-26 2004-09-16 Bristol-Myers Squibb Company Compositions and methods for hydroxylating epothilones
WO2011038313A2 (en) 2009-09-25 2011-03-31 Regents Of The University Of Michigan Selective oxidation of c-h bonds of modified substrates by p450 monooxygenase
WO2012109586A2 (en) 2011-02-11 2012-08-16 University Of Rochester Methods and systems for evaluating and predicting the reactivity of monooxygenase enzymes
WO2013073775A1 (en) 2011-11-15 2013-05-23 Industry Foundation Of Chonnam National University Novel method for preparing metabolites of atorvastatin using bacterial cytochrome p450 and composition therefor
GB201807815D0 (en) * 2018-05-14 2018-06-27 Hypha Discovery Ltd Hydroxylation techniques

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