|
DE3825615A1
(de)
|
1988-07-28 |
1990-02-01 |
Behringwerke Ag |
Antigenkonstrukte von "major histocompatibility complex" klasse i antigenen mit spezifischen traegermolekuelen, ihre herstellung und verwendung
|
|
US6352694B1
(en)
|
1994-06-03 |
2002-03-05 |
Genetics Institute, Inc. |
Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells
|
|
US6905680B2
(en)
|
1988-11-23 |
2005-06-14 |
Genetics Institute, Inc. |
Methods of treating HIV infected subjects
|
|
US6534055B1
(en)
|
1988-11-23 |
2003-03-18 |
Genetics Institute, Inc. |
Methods for selectively stimulating proliferation of T cells
|
|
US7479269B2
(en)
|
1988-11-23 |
2009-01-20 |
Genetics Institute, Llc |
Methods for selectively enriching TH1 and TH2 cells
|
|
US5858358A
(en)
|
1992-04-07 |
1999-01-12 |
The United States Of America As Represented By The Secretary Of The Navy |
Methods for selectively stimulating proliferation of T cells
|
|
JP2618497B2
(ja)
|
1989-10-03 |
1997-06-11 |
鐘淵化学工業株式会社 |
腫瘍障害細胞誘導剤および腫瘍障害細胞誘導デバイス
|
|
US6106835A
(en)
|
1991-04-19 |
2000-08-22 |
Tanox, Inc. |
Modified binding molecules specific for T or B lymphocytes and their use as in vivo immune modulators
|
|
US5872222A
(en)
|
1991-04-19 |
1999-02-16 |
Tanox Biosystems, Inc. |
Conjugates of polymers and antibodies specific for T lymphocytes, and their use as adjuvants
|
|
CA2065658A1
(en)
|
1991-04-19 |
1992-10-20 |
Tse-Wen Chang |
Conjugates of liposomes or microbeads and antibodies specific for t lymphocytes and their use in vivo immune modulators
|
|
US6129916A
(en)
|
1991-04-19 |
2000-10-10 |
Tanox, Inc. |
Method of Increasing activation on proliferation of T cells using antibody-microbead conjugates
|
|
US6197298B1
(en)
|
1991-04-19 |
2001-03-06 |
Tanox, Inc. |
Modified binding molecules specific for T lymphocytes and their use as in vivo immune modulators in animals
|
|
DE4237113B4
(de)
|
1992-11-03 |
2006-10-12 |
"Iba Gmbh" |
Peptide und deren Fusionsproteine, Expressionsvektor und Verfahren zur Herstellung eines Fusionsproteins
|
|
WO1994012196A1
(en)
|
1992-11-25 |
1994-06-09 |
Tanox Biosystems, Inc. |
Conjugates and constructs including anti-cd28 and anti-cd3 binding molecules
|
|
DE69418699T2
(de)
|
1993-01-11 |
1999-09-30 |
Dana-Farber Cancer Institute, Boston |
Induktion der antworten zytotoxischer t-lymphozyten
|
|
AU7052194A
(en)
|
1993-06-04 |
1995-01-03 |
Regents Of The University Of Michigan, The |
Methods for selectively stimulating proliferation of t cells
|
|
CA2164646A1
(en)
|
1993-06-11 |
1994-12-22 |
Wade E. Bolton |
Anti-cd3 antibody-aminodextran conjugates for induction of t-cell activation and proliferation
|
|
US5635602A
(en)
|
1993-08-13 |
1997-06-03 |
The Regents Of The University Of California |
Design and synthesis of bispecific DNA-antibody conjugates
|
|
EP0764203A1
(en)
|
1994-06-03 |
1997-03-26 |
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY |
Methods for selectively stimulating proliferation of t cells
|
|
US7175843B2
(en)
|
1994-06-03 |
2007-02-13 |
Genetics Institute, Llc |
Methods for selectively stimulating proliferation of T cells
|
|
US7074904B2
(en)
|
1994-07-29 |
2006-07-11 |
Altor Bioscience Corporation |
MHC complexes and uses thereof
|
|
DE69628154T2
(de)
|
1995-03-08 |
2004-03-18 |
The Scripps Research Institute, La Jolla |
Antigen präsentierendes system und aktivierung von t-zellen
|
|
US6692964B1
(en)
|
1995-05-04 |
2004-02-17 |
The United States Of America As Represented By The Secretary Of The Navy |
Methods for transfecting T cells
|
|
US7067318B2
(en)
|
1995-06-07 |
2006-06-27 |
The Regents Of The University Of Michigan |
Methods for transfecting T cells
|
|
JP4031033B2
(ja)
|
1995-05-04 |
2008-01-09 |
アメリカ合衆国 |
Ｔ細胞の改良トランスフェクション法
|
|
AU729406B2
(en)
|
1996-03-28 |
2001-02-01 |
Johns Hopkins University, The |
Soluble divalent and multivalent heterodimeric analogs of proteins
|
|
US6458354B1
(en)
|
1996-03-28 |
2002-10-01 |
The Johns Hopkins University |
Molecular complexes which modify immune responses
|
|
US7973137B1
(en)
|
1996-03-28 |
2011-07-05 |
Johns Hopkins University |
Cell compositions comprising molecular complexes that modify immune responses
|
|
DK0937251T3
(da)
|
1996-09-06 |
2007-02-19 |
Ortho Mcneil Pharm Inc |
Oprensning af antigenspecifikke T-celler
|
|
DE19641876B4
(de)
|
1996-10-10 |
2011-09-29 |
Iba Gmbh |
Streptavidinmuteine
|
|
US6077833A
(en)
|
1996-12-31 |
2000-06-20 |
Isis Pharmaceuticals, Inc. |
Oligonucleotide compositions and methods for the modulation of the expression of B7 protein
|
|
US7927595B1
(en)
|
1997-02-21 |
2011-04-19 |
The United States Of America As Represented By The Secretary Of The Navy |
Methods for downregulating CCR5 in T cells with anti-CD3 antibodies and anti-CD28 antibodies
|
|
US6268411B1
(en)
|
1997-09-11 |
2001-07-31 |
The Johns Hopkins University |
Use of multivalent chimeric peptide-loaded, MHC/ig molecules to detect, activate or suppress antigen-specific T cell-dependent immune responses
|
|
FR2766205B1
(fr)
|
1997-07-16 |
2002-08-30 |
Inst Nat Sante Rech Med |
Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede
|
|
US6248564B1
(en)
|
1997-08-29 |
2001-06-19 |
Harvard University |
Mutant MHC class I molecules
|
|
EP1017721B1
(en)
|
1997-09-16 |
2009-02-25 |
Oregon Health and Science University |
Recombinant mhc molecules useful for manipulation of antigen-specific t-cells
|
|
US6232445B1
(en)
|
1997-10-29 |
2001-05-15 |
Sunol Molecular Corporation |
Soluble MHC complexes and methods of use thereof
|
|
EP0941766B1
(en)
|
1998-03-12 |
2006-12-20 |
Miltenyi Biotec GmbH |
Micro column system for magnetic separation
|
|
GB2339782A
(en)
|
1998-06-05 |
2000-02-09 |
Philip Michael Savage |
Chimeric protein complexes comprising HLA class I antigens
|
|
US7264965B2
(en)
|
1998-06-05 |
2007-09-04 |
Alexis Biotech Limited |
Method for producing or enhancing a T-cell response against a target cell using a complex comprising an HLA class I molecule and an attaching means
|
|
US7521197B2
(en)
|
1998-06-05 |
2009-04-21 |
Alexis Biotech Limited |
Method for producing cytotoxic T-cells
|
|
US20020051783A1
(en)
|
1998-06-05 |
2002-05-02 |
Savage Philip Michael |
Method for producing or enhancing a T-cell response against a target cell using a complex comprising an HLA class I molecule and an attaching means
|
|
DE69942100D1
(de)
|
1998-10-20 |
2010-04-15 |
Androclus Technologies S R L I |
Künstliche antigen-spezifischen zellen und zugehörige verfahren
|
|
US6787154B2
(en)
|
1998-10-20 |
2004-09-07 |
Salvatore Albani |
Artificial antigen presenting cells
|
|
US6590076B1
(en)
|
1999-04-02 |
2003-07-08 |
Corixa Corporation |
Compositions for the treatment and diagnosis of breast cancer and methods for their use
|
|
CA2406864A1
(en)
|
2000-02-24 |
2001-08-30 |
Xcyte Therapies, Inc. |
Simultaneous stimulation and concentration of cells
|
|
US6867041B2
(en)
|
2000-02-24 |
2005-03-15 |
Xcyte Therapies, Inc. |
Simultaneous stimulation and concentration of cells
|
|
US20030119185A1
(en)
|
2000-02-24 |
2003-06-26 |
Xcyte Therapies, Inc. |
Activation and expansion of cells
|
|
EP1526171A1
(en)
|
2000-02-24 |
2005-04-27 |
Xcyte Therapies, Inc |
Simultaneous stimulation and concentration of cells
|
|
US7541184B2
(en)
|
2000-02-24 |
2009-06-02 |
Invitrogen Corporation |
Activation and expansion of cells
|
|
US6797514B2
(en)
|
2000-02-24 |
2004-09-28 |
Xcyte Therapies, Inc. |
Simultaneous stimulation and concentration of cells
|
|
US7572631B2
(en)
|
2000-02-24 |
2009-08-11 |
Invitrogen Corporation |
Activation and expansion of T cells
|
|
US20030235908A1
(en)
|
2000-02-24 |
2003-12-25 |
Xcyte Therapies, Inc. |
Activation and expansion of cells
|
|
US6902933B2
(en)
|
2000-11-03 |
2005-06-07 |
Regents Of The University Of Michigan |
Surface transfection and expression procedure
|
|
KR20030093185A
(ko)
|
2000-11-03 |
2003-12-06 |
리젠츠 오브 더 유니버시티 오브 미시간 |
표면 형질감염 및 발현 방법
|
|
US6897067B2
(en)
|
2000-11-03 |
2005-05-24 |
Regents Of The University Of Michigan |
Surface transfection and expression procedure
|
|
EP1227321A1
(en)
|
2000-12-28 |
2002-07-31 |
Institut für Bioanalytik GmbH |
Reversible MHC multimer staining for functional purification of antigen-specific T cells
|
|
DE10113776B4
(de)
|
2001-03-21 |
2012-08-09 |
"Iba Gmbh" |
Isoliertes streptavidinbindendes, kompetitiv eluierbares Peptid, dieses umfassendes Fusionspeptid, dafür codierende Nukleinsäure, Expressionsvektor, Verfahren zur Herstellung eines rekombinanten Fusionsproteins und Verfahren zum Nachweis und/oder zur Gewinnung des Fusionsproteins
|
|
US7745140B2
(en)
|
2002-01-03 |
2010-06-29 |
The Trustees Of The University Of Pennsylvania |
Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool
|
|
US7670781B2
(en)
|
2002-01-03 |
2010-03-02 |
The Trustees Of The University Of Pennsylvania |
Activation and expansion of T-cells using an agent that provides a primary activation signal and another agent that provides a co-stimulatory signal
|
|
CN100379852C
(zh)
*
|
2002-02-08 |
2008-04-09 |
埃克斯西特治疗公司 |
用于在免疫缺陷患者体内恢复免疫响应的组合物和方法
|
|
CA2474186A1
(en)
|
2002-02-08 |
2003-08-14 |
Xcyte Therapies, Inc. |
Compositions and methods for restoring immune responsiveness in patients with immunological defects
|
|
US20040175373A1
(en)
|
2002-06-28 |
2004-09-09 |
Xcyte Therapies, Inc. |
Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
|
|
US20050084967A1
(en)
|
2002-06-28 |
2005-04-21 |
Xcyte Therapies, Inc. |
Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
|
|
US20040151704A1
(en)
|
2002-06-28 |
2004-08-05 |
Xcyte Therapies, Inc. |
Compositions and methods for restoring immune repertoire in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
|
|
CA2800113C
(en)
|
2002-07-12 |
2015-02-03 |
The Johns Hopkins University |
Reagents and methods for engaging unique clonotypic lymphocyte receptors
|
|
GB2392158B
(en)
|
2002-08-21 |
2005-02-16 |
Proimmune Ltd |
Chimeric MHC protein and oligomer thereof
|
|
EP1623017B1
(en)
|
2003-05-08 |
2010-09-15 |
Life Technologies Corporation |
Generation and isolation of antigen-specific t cells
|
|
US7402431B2
(en)
|
2004-03-01 |
2008-07-22 |
Immunovative Therapies, Ltd. |
T-cell therapy formulation
|
|
US7435592B2
(en)
|
2003-05-13 |
2008-10-14 |
Immunovative Therapies, Ltd. |
Compositions for allogeneic cell therapy
|
|
WO2005049085A1
(en)
|
2003-11-18 |
2005-06-02 |
Valeocyte Therapies Llc |
Use of soluble complexes to facilitate cell activation
|
|
WO2005065121A2
(en)
|
2003-12-02 |
2005-07-21 |
Cytimmune Sciences, Inc. |
Methods and compositions for the production of monoclonal antibodies
|
|
US7592431B2
(en)
|
2004-02-26 |
2009-09-22 |
Immunovative Therapies, Ltd. |
Biodegradable T-cell Activation device
|
|
PT2573166T
(pt)
|
2004-02-26 |
2016-07-07 |
Immunovative Therapies Ltd |
Métodos para preparar células-t para terapia celular
|
|
ATE449161T1
(de)
|
2004-03-04 |
2009-12-15 |
Leukocare Ag |
Leukozytenstimulations-matrix
|
|
GB2422834B8
(en)
|
2005-02-04 |
2007-01-04 |
Proimmune Ltd |
MHC oligomer and method of making the same
|
|
JP2006345852A
(ja)
|
2005-06-16 |
2006-12-28 |
Virxsys Corp |
抗体複合体
|
|
GB0603081D0
(en)
|
2006-02-15 |
2006-03-29 |
Dynal Biotech Asa Oslo |
Method
|
|
GB2442048B
(en)
|
2006-07-25 |
2009-09-30 |
Proimmune Ltd |
Biotinylated MHC complexes and their uses
|
|
KR20090060450A
(ko)
|
2006-10-04 |
2009-06-12 |
얀센 파마슈티카 엔.브이. |
불활성화 인공 항원 제시 세포의 제조 및 세포 치료법에서 이들의 용도
|
|
EP2155782A2
(en)
|
2007-03-26 |
2010-02-24 |
Dako Denmark A/S |
Mhc peptide complexes and uses thereof in infectious diseases
|
|
US20100143905A1
(en)
|
2007-03-29 |
2010-06-10 |
Lane Michael J |
Methods and compositions for multivalent binding and methods for manufacture of rapid diagnostic tests
|
|
US8629098B2
(en)
|
2008-01-15 |
2014-01-14 |
Yale University |
Compositions and methods for adoptive and active immunotherapy
|
|
WO2009117616A2
(en)
|
2008-03-19 |
2009-09-24 |
Yale University |
Carbon nanotube compositions and methods of use thereof
|
|
US20110318380A1
(en)
|
2008-10-01 |
2011-12-29 |
Dako Denmark A/S |
MHC Multimers in Cancer Vaccines and Immune Monitoring
|
|
WO2011050000A2
(en)
|
2009-10-20 |
2011-04-28 |
The Regents Of The University Of California |
Single molecule nucleic acid nanoparticles
|
|
GB201002730D0
(en)
|
2010-02-18 |
2010-04-07 |
Uni I Oslo |
Product
|
|
US8945509B2
(en)
|
2010-08-20 |
2015-02-03 |
Life Technologies Corporation |
Magnetic beads having surface glycoconjugates and use thereof
|
|
US10023657B2
(en)
|
2010-10-01 |
2018-07-17 |
Ludwig Institute For Cancer Research Ltd. |
Reversible protein multimers, methods for their production and use
|
|
EP3418295B1
(en)
|
2011-07-18 |
2020-09-02 |
IBA GmbH |
Method of reversibly staining a target cell
|
|
US8834889B2
(en)
|
2011-08-29 |
2014-09-16 |
National Tsing Hua University |
Antigen presenting composition and use thereof
|
|
CA2858115A1
(en)
|
2011-12-09 |
2013-06-13 |
The Johns Hopkins University |
Artificial antigen presenting cells having a defined and dynamic shape
|
|
WO2013109568A1
(en)
|
2012-01-17 |
2013-07-25 |
Croda, Inc. |
Seal swell additive
|
|
AU2013224027B2
(en)
|
2012-02-23 |
2019-01-24 |
Juno Therapeutics Gmbh |
Chromatographic isolation of cells and other complex biological materials
|
|
EP2711418B1
(en)
|
2012-09-25 |
2017-08-23 |
Miltenyi Biotec GmbH |
Method for polyclonal stimulation of T cells by flexible nanomatrices
|
|
CN105073770B
(zh)
|
2012-11-16 |
2019-08-06 |
Iba股份有限公司 |
链霉亲和素突变蛋白及其使用方法
|
|
WO2014127220A1
(en)
|
2013-02-15 |
2014-08-21 |
The Johns Hopkins University |
Antigen-specific t cell redirectors
|
|
JP6501270B2
(ja)
|
2013-03-14 |
2019-04-17 |
ザ カリフォルニア インスティテュート フォー バイオメディカル リサーチ |
標的化剤抗体抱合体およびその使用
|
|
KR102164405B1
(ko)
|
2013-03-14 |
2020-10-12 |
더 존스 홉킨스 유니버시티 |
나노스케일 인공 항원 제시 세포
|
|
WO2014209868A1
(en)
|
2013-06-24 |
2014-12-31 |
Neximmune |
Compositions and methods for immunotherapy
|
|
EP2824112B1
(en)
*
|
2013-07-10 |
2016-12-21 |
Miltenyi Biotec GmbH |
Method for inducing proliferation of Natural Killer cells by mobile nanomatrices
|
|
JP5799058B2
(ja)
|
2013-07-30 |
2015-10-21 |
三桜工業株式会社 |
負圧ポンプ及びシリンダヘッドカバー
|
|
JP6696969B2
(ja)
|
2014-04-16 |
2020-05-20 |
ユノ・セラピューティクス・ゲーエムベーハーＪｕｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｇｍｂｈ |
細胞の集団を拡大する方法、キット、及び装置
|
|
CA2996848C
(en)
*
|
2014-09-04 |
2021-01-05 |
Stemcell Technologies Inc. |
Soluble antibody complexes for t cell or nk cell activation and expansion
|
|
US10294454B2
(en)
|
2016-08-24 |
2019-05-21 |
General Electric Company |
Methods and kits for cell activation
|