|
DE3825615A1
(de)
|
1988-07-28 |
1990-02-01 |
Behringwerke Ag |
Antigenkonstrukte von "major histocompatibility complex" klasse i antigenen mit spezifischen traegermolekuelen, ihre herstellung und verwendung
|
|
US5858358A
(en)
|
1992-04-07 |
1999-01-12 |
The United States Of America As Represented By The Secretary Of The Navy |
Methods for selectively stimulating proliferation of T cells
|
|
US6534055B1
(en)
|
1988-11-23 |
2003-03-18 |
Genetics Institute, Inc. |
Methods for selectively stimulating proliferation of T cells
|
|
US6352694B1
(en)
|
1994-06-03 |
2002-03-05 |
Genetics Institute, Inc. |
Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells
|
|
US7479269B2
(en)
*
|
1988-11-23 |
2009-01-20 |
Genetics Institute, Llc |
Methods for selectively enriching TH1 and TH2 cells
|
|
US6905680B2
(en)
|
1988-11-23 |
2005-06-14 |
Genetics Institute, Inc. |
Methods of treating HIV infected subjects
|
|
JP2618497B2
(ja)
|
1989-10-03 |
1997-06-11 |
鐘淵化学工業株式会社 |
腫瘍障害細胞誘導剤および腫瘍障害細胞誘導デバイス
|
|
US6197298B1
(en)
|
1991-04-19 |
2001-03-06 |
Tanox, Inc. |
Modified binding molecules specific for T lymphocytes and their use as in vivo immune modulators in animals
|
|
US5872222A
(en)
|
1991-04-19 |
1999-02-16 |
Tanox Biosystems, Inc. |
Conjugates of polymers and antibodies specific for T lymphocytes, and their use as adjuvants
|
|
US6129916A
(en)
|
1991-04-19 |
2000-10-10 |
Tanox, Inc. |
Method of Increasing activation on proliferation of T cells using antibody-microbead conjugates
|
|
CA2065658A1
(en)
|
1991-04-19 |
1992-10-20 |
Tse-Wen Chang |
Conjugates of liposomes or microbeads and antibodies specific for t lymphocytes and their use in vivo immune modulators
|
|
US6106835A
(en)
|
1991-04-19 |
2000-08-22 |
Tanox, Inc. |
Modified binding molecules specific for T or B lymphocytes and their use as in vivo immune modulators
|
|
DE4237113B4
(de)
|
1992-11-03 |
2006-10-12 |
"Iba Gmbh" |
Peptide und deren Fusionsproteine, Expressionsvektor und Verfahren zur Herstellung eines Fusionsproteins
|
|
WO1994012196A1
(en)
|
1992-11-25 |
1994-06-09 |
Tanox Biosystems, Inc. |
Conjugates and constructs including anti-cd28 and anti-cd3 binding molecules
|
|
JPH08505625A
(ja)
|
1993-01-11 |
1996-06-18 |
ダナ−ファーバー キャンサー インスティチュート |
細胞毒性ｔリンパ球応答の誘導
|
|
WO1994029436A1
(en)
|
1993-06-04 |
1994-12-22 |
The United States Of America Represented By The Secretary Of The Navy |
Methods for selectively stimulating proliferation of t cells
|
|
EP0702793B1
(en)
|
1993-06-11 |
2003-08-27 |
Coulter International Corporation |
Anti-cd3 antibody-aminodextran conjugates for induction of t-cell activation and proliferation
|
|
US5635602A
(en)
|
1993-08-13 |
1997-06-03 |
The Regents Of The University Of California |
Design and synthesis of bispecific DNA-antibody conjugates
|
|
US7175843B2
(en)
|
1994-06-03 |
2007-02-13 |
Genetics Institute, Llc |
Methods for selectively stimulating proliferation of T cells
|
|
CA2191586A1
(en)
|
1994-06-03 |
1995-12-14 |
Carl H. June |
Methods for selectively stimulating proliferation of t cells
|
|
US7074904B2
(en)
|
1994-07-29 |
2006-07-11 |
Altor Bioscience Corporation |
MHC complexes and uses thereof
|
|
EP0814838B1
(en)
|
1995-03-08 |
2003-05-14 |
The Scripps Research Institute |
Antigen presenting system and activation of t-cells
|
|
EP0824594B1
(en)
|
1995-05-04 |
2005-04-06 |
The United States of America as Representend by The Secretary of the Navy |
Improved methods for transfecting t cells
|
|
US7067318B2
(en)
|
1995-06-07 |
2006-06-27 |
The Regents Of The University Of Michigan |
Methods for transfecting T cells
|
|
US6692964B1
(en)
|
1995-05-04 |
2004-02-17 |
The United States Of America As Represented By The Secretary Of The Navy |
Methods for transfecting T cells
|
|
US7973137B1
(en)
|
1996-03-28 |
2011-07-05 |
Johns Hopkins University |
Cell compositions comprising molecular complexes that modify immune responses
|
|
US6458354B1
(en)
|
1996-03-28 |
2002-10-01 |
The Johns Hopkins University |
Molecular complexes which modify immune responses
|
|
EP0889964A1
(en)
|
1996-03-28 |
1999-01-13 |
The Johns Hopkins University |
Soluble divalent and multivalent heterodimeric analogs of proteins
|
|
EP0937251B1
(en)
|
1996-09-06 |
2006-11-29 |
Ortho-McNeil Pharmaceutical, Inc. |
Purification of antigen-specific t cells
|
|
DE19641876B4
(de)
|
1996-10-10 |
2011-09-29 |
Iba Gmbh |
Streptavidinmuteine
|
|
US6077833A
(en)
|
1996-12-31 |
2000-06-20 |
Isis Pharmaceuticals, Inc. |
Oligonucleotide compositions and methods for the modulation of the expression of B7 protein
|
|
US7927595B1
(en)
|
1997-02-21 |
2011-04-19 |
The United States Of America As Represented By The Secretary Of The Navy |
Methods for downregulating CCR5 in T cells with anti-CD3 antibodies and anti-CD28 antibodies
|
|
US6268411B1
(en)
|
1997-09-11 |
2001-07-31 |
The Johns Hopkins University |
Use of multivalent chimeric peptide-loaded, MHC/ig molecules to detect, activate or suppress antigen-specific T cell-dependent immune responses
|
|
FR2766205B1
(fr)
|
1997-07-16 |
2002-08-30 |
Inst Nat Sante Rech Med |
Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede
|
|
US6248564B1
(en)
|
1997-08-29 |
2001-06-19 |
Harvard University |
Mutant MHC class I molecules
|
|
DK1017721T3
(da)
|
1997-09-16 |
2009-04-20 |
Univ Oregon Health & Science |
Rekombinante MHC molekyler, der kan anvendes til manipulation af antigenspecifikke T-celler
|
|
US6232445B1
(en)
|
1997-10-29 |
2001-05-15 |
Sunol Molecular Corporation |
Soluble MHC complexes and methods of use thereof
|
|
DE69934449T2
(de)
|
1998-03-12 |
2007-09-27 |
Miltenyi Biotech Gmbh |
Mikrokolonnen-System für Magnettrennung
|
|
US7264965B2
(en)
|
1998-06-05 |
2007-09-04 |
Alexis Biotech Limited |
Method for producing or enhancing a T-cell response against a target cell using a complex comprising an HLA class I molecule and an attaching means
|
|
US20020051783A1
(en)
|
1998-06-05 |
2002-05-02 |
Savage Philip Michael |
Method for producing or enhancing a T-cell response against a target cell using a complex comprising an HLA class I molecule and an attaching means
|
|
GB2339782A
(en)
|
1998-06-05 |
2000-02-09 |
Philip Michael Savage |
Chimeric protein complexes comprising HLA class I antigens
|
|
US7521197B2
(en)
|
1998-06-05 |
2009-04-21 |
Alexis Biotech Limited |
Method for producing cytotoxic T-cells
|
|
JP2002527467A
(ja)
|
1998-10-20 |
2002-08-27 |
サルバトーレ・アルバーニ |
抗原特異的ｔ細胞の単離、定量、特徴づけおよび調節方法
|
|
US6787154B2
(en)
|
1998-10-20 |
2004-09-07 |
Salvatore Albani |
Artificial antigen presenting cells
|
|
US6590076B1
(en)
|
1999-04-02 |
2003-07-08 |
Corixa Corporation |
Compositions for the treatment and diagnosis of breast cancer and methods for their use
|
|
US20030235908A1
(en)
|
2000-02-24 |
2003-12-25 |
Xcyte Therapies, Inc. |
Activation and expansion of cells
|
|
EP1526171A1
(en)
|
2000-02-24 |
2005-04-27 |
Xcyte Therapies, Inc |
Simultaneous stimulation and concentration of cells
|
|
BR0108545A
(pt)
*
|
2000-02-24 |
2004-06-29 |
Xcyte Therapies Inc |
Estimulação e concentração simultâneas das células
|
|
US20030119185A1
(en)
|
2000-02-24 |
2003-06-26 |
Xcyte Therapies, Inc. |
Activation and expansion of cells
|
|
US6797514B2
(en)
|
2000-02-24 |
2004-09-28 |
Xcyte Therapies, Inc. |
Simultaneous stimulation and concentration of cells
|
|
US7541184B2
(en)
|
2000-02-24 |
2009-06-02 |
Invitrogen Corporation |
Activation and expansion of cells
|
|
US7572631B2
(en)
|
2000-02-24 |
2009-08-11 |
Invitrogen Corporation |
Activation and expansion of T cells
|
|
US6867041B2
(en)
|
2000-02-24 |
2005-03-15 |
Xcyte Therapies, Inc. |
Simultaneous stimulation and concentration of cells
|
|
US6902933B2
(en)
|
2000-11-03 |
2005-06-07 |
Regents Of The University Of Michigan |
Surface transfection and expression procedure
|
|
EP1330516B1
(en)
|
2000-11-03 |
2007-01-17 |
The Regents Of The University Of Michigan |
Surface transfection and expression procedure
|
|
US6897067B2
(en)
|
2000-11-03 |
2005-05-24 |
Regents Of The University Of Michigan |
Surface transfection and expression procedure
|
|
EP1227321A1
(en)
|
2000-12-28 |
2002-07-31 |
Institut für Bioanalytik GmbH |
Reversible MHC multimer staining for functional purification of antigen-specific T cells
|
|
DE10113776B4
(de)
|
2001-03-21 |
2012-08-09 |
"Iba Gmbh" |
Isoliertes streptavidinbindendes, kompetitiv eluierbares Peptid, dieses umfassendes Fusionspeptid, dafür codierende Nukleinsäure, Expressionsvektor, Verfahren zur Herstellung eines rekombinanten Fusionsproteins und Verfahren zum Nachweis und/oder zur Gewinnung des Fusionsproteins
|
|
AU2003202908A1
(en)
|
2002-01-03 |
2003-07-24 |
The Trustees Of The University Of Pennsylvania |
Activation and expansion of t-cells using an engineered multivalent signaling platform
|
|
US7745140B2
(en)
|
2002-01-03 |
2010-06-29 |
The Trustees Of The University Of Pennsylvania |
Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool
|
|
CN100379852C
(zh)
*
|
2002-02-08 |
2008-04-09 |
埃克斯西特治疗公司 |
用于在免疫缺陷患者体内恢复免疫响应的组合物和方法
|
|
EP2034009B1
(en)
|
2002-02-08 |
2014-01-15 |
Life Technologies Corporation |
Compositions and methods for restoring immune responsiveness in patients with immunological defects basing on cd3/cd28 costimulation
|
|
US20040151704A1
(en)
|
2002-06-28 |
2004-08-05 |
Xcyte Therapies, Inc. |
Compositions and methods for restoring immune repertoire in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
|
|
US20040175373A1
(en)
|
2002-06-28 |
2004-09-09 |
Xcyte Therapies, Inc. |
Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
|
|
US20050084967A1
(en)
|
2002-06-28 |
2005-04-21 |
Xcyte Therapies, Inc. |
Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
|
|
CA2493081C
(en)
|
2002-07-12 |
2013-04-23 |
The Johns Hopkins University |
Reagents and methods for engaging unique clonotypic lymphocyte receptors
|
|
GB2392158B
(en)
|
2002-08-21 |
2005-02-16 |
Proimmune Ltd |
Chimeric MHC protein and oligomer thereof
|
|
DE60334250D1
(de)
|
2003-05-08 |
2010-10-28 |
Life Technologies Corp |
Erzeugung und isolierung antigenspezifischer t-zellen
|
|
US7435592B2
(en)
|
2003-05-13 |
2008-10-14 |
Immunovative Therapies, Ltd. |
Compositions for allogeneic cell therapy
|
|
US7402431B2
(en)
|
2004-03-01 |
2008-07-22 |
Immunovative Therapies, Ltd. |
T-cell therapy formulation
|
|
WO2005049085A1
(en)
|
2003-11-18 |
2005-06-02 |
Valeocyte Therapies Llc |
Use of soluble complexes to facilitate cell activation
|
|
AU2004311630A1
(en)
|
2003-12-02 |
2005-07-21 |
Cytimmune Sciences, Inc. |
Methods and compositions for the production of monoclonal antibodies
|
|
SI2573166T1
(sl)
|
2004-02-26 |
2016-09-30 |
Immunovative Therapies, Ltd. |
Metode za pripravo T-celic za celično terapijo
|
|
US7592431B2
(en)
|
2004-02-26 |
2009-09-22 |
Immunovative Therapies, Ltd. |
Biodegradable T-cell Activation device
|
|
DE502004010393D1
(de)
|
2004-03-04 |
2009-12-31 |
Leukocare Gmbh |
Leukozytenstimulations-Matrix
|
|
GB2422834B8
(en)
|
2005-02-04 |
2007-01-04 |
Proimmune Ltd |
MHC oligomer and method of making the same
|
|
JP2006345852A
(ja)
*
|
2005-06-16 |
2006-12-28 |
Virxsys Corp |
抗体複合体
|
|
GB0603081D0
(en)
|
2006-02-15 |
2006-03-29 |
Dynal Biotech Asa Oslo |
Method
|
|
GB2442048B
(en)
|
2006-07-25 |
2009-09-30 |
Proimmune Ltd |
Biotinylated MHC complexes and their uses
|
|
CA2665568C
(en)
|
2006-10-04 |
2018-01-09 |
Janssen Pharmaceutica, N.V. |
Preparation of inactivated artificial antigen presenting cells and their use in cell therapies
|
|
EP2155782A2
(en)
|
2007-03-26 |
2010-02-24 |
Dako Denmark A/S |
Mhc peptide complexes and uses thereof in infectious diseases
|
|
WO2009005552A2
(en)
|
2007-03-29 |
2009-01-08 |
Epitype Corporation |
Methods and compositions for multivalent binding and methods for manufacture of rapid diagnostic tests
|
|
WO2009094273A2
(en)
|
2008-01-15 |
2009-07-30 |
Yale University |
Compositions and methods for adoptive and active immunotherapy
|
|
US8658178B2
(en)
|
2008-03-19 |
2014-02-25 |
Yale University |
Carbon nanotube compositions and methods of use thereof
|
|
US20110318380A1
(en)
|
2008-10-01 |
2011-12-29 |
Dako Denmark A/S |
MHC Multimers in Cancer Vaccines and Immune Monitoring
|
|
EP2491123B1
(en)
|
2009-10-20 |
2018-04-18 |
The Regents of The University of California |
Single molecule nucleic acid nanoparticles
|
|
GB201002730D0
(en)
|
2010-02-18 |
2010-04-07 |
Uni I Oslo |
Product
|
|
US8945509B2
(en)
|
2010-08-20 |
2015-02-03 |
Life Technologies Corporation |
Magnetic beads having surface glycoconjugates and use thereof
|
|
US10023657B2
(en)
|
2010-10-01 |
2018-07-17 |
Ludwig Institute For Cancer Research Ltd. |
Reversible protein multimers, methods for their production and use
|
|
US9023604B2
(en)
|
2011-07-18 |
2015-05-05 |
Iba Gmbh |
Method of reversibly staining a target cell
|
|
US8834889B2
(en)
|
2011-08-29 |
2014-09-16 |
National Tsing Hua University |
Antigen presenting composition and use thereof
|
|
WO2013086500A1
(en)
|
2011-12-09 |
2013-06-13 |
The Johns Hopkins University |
Artificial antigen presenting cells having a defined and dynamic shape
|
|
ES2680549T3
(es)
|
2012-01-17 |
2018-09-10 |
Croda, Inc. |
Uso de un diéster de isosorbida como aditivo de hinchamiento de juntas
|
|
JP6362543B2
(ja)
|
2012-02-23 |
2018-07-25 |
ジュノ セラピューティクス ゲーエムベーハー |
細胞および他の複雑な生物学的材料のクロマトグラフィーによる単離
|
|
EP2711418B1
(en)
|
2012-09-25 |
2017-08-23 |
Miltenyi Biotec GmbH |
Method for polyclonal stimulation of T cells by flexible nanomatrices
|
|
CA2891820A1
(en)
|
2012-11-16 |
2014-05-22 |
Iba Gmbh |
Streptavidin muteins and methods of using them
|
|
ES2820729T3
(es)
|
2013-02-15 |
2021-04-22 |
Univ Johns Hopkins |
Redirectores de células T específicas de antígenos
|
|
KR102164405B1
(ko)
|
2013-03-14 |
2020-10-12 |
더 존스 홉킨스 유니버시티 |
나노스케일 인공 항원 제시 세포
|
|
JP6501270B2
(ja)
|
2013-03-14 |
2019-04-17 |
ザ カリフォルニア インスティテュート フォー バイオメディカル リサーチ |
標的化剤抗体抱合体およびその使用
|
|
CN113797332B
(zh)
|
2013-06-24 |
2024-08-09 |
耐克西缪恩公司 |
用于免疫疗法的组合物和方法
|
|
ES2612918T3
(es)
*
|
2013-07-10 |
2017-05-19 |
Miltenyi Biotec Gmbh |
Método para inducir la proliferación de células asesinas naturales por nanomatrices móviles
|
|
JP5799058B2
(ja)
|
2013-07-30 |
2015-10-21 |
三桜工業株式会社 |
負圧ポンプ及びシリンダヘッドカバー
|
|
LT3132247T
(lt)
|
2014-04-16 |
2021-12-10 |
Juno Therapeutics Gmbh |
Ląstelių populiacijos padauginimo būdai, rinkiniai ir priemonės
|
|
ES2808914T3
(es)
|
2014-09-04 |
2021-03-02 |
Stemcell Tech Inc |
Complejos de anticuerpo solubles para la activación y expansión de linfocitos T o células NK
|
|
US10294454B2
(en)
|
2016-08-24 |
2019-05-21 |
General Electric Company |
Methods and kits for cell activation
|