JP2019533722A5 - - Google Patents
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- JP2019533722A5 JP2019533722A5 JP2019540514A JP2019540514A JP2019533722A5 JP 2019533722 A5 JP2019533722 A5 JP 2019533722A5 JP 2019540514 A JP2019540514 A JP 2019540514A JP 2019540514 A JP2019540514 A JP 2019540514A JP 2019533722 A5 JP2019533722 A5 JP 2019533722A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- peptide
- seq
- eye
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 108090000765 processed proteins & peptides Proteins 0.000 claims 7
- 208000030533 eye disease Diseases 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 208000028006 Corneal injury Diseases 0.000 claims 1
- 208000003556 Dry Eye Syndromes Diseases 0.000 claims 1
- 206010013774 Dry eye Diseases 0.000 claims 1
- 230000021736 acetylation Effects 0.000 claims 1
- 238000006640 acetylation reaction Methods 0.000 claims 1
- 230000009435 amidation Effects 0.000 claims 1
- 238000007112 amidation reaction Methods 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022155973A JP2022185042A (ja) | 2016-10-07 | 2022-09-29 | Ｐｅｄｆ由来短ペプチドを含む組成物およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662405522P | 2016-10-07 | 2016-10-07 | |
| US62/405,522 | 2016-10-07 | ||
| PCT/US2017/048340 WO2018067244A1 (en) | 2016-10-07 | 2017-08-24 | Compositions comprising pedf-derived short peptides and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022155973A Division JP2022185042A (ja) | 2016-10-07 | 2022-09-29 | Ｐｅｄｆ由来短ペプチドを含む組成物およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019533722A JP2019533722A (ja) | 2019-11-21 |
| JP2019533722A5 true JP2019533722A5 (enrdf_load_stackoverflow) | 2020-10-01 |
| JP7573967B2 JP7573967B2 (ja) | 2024-10-28 |
Family
ID=61831898
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019540514A Active JP7573967B2 (ja) | 2016-10-07 | 2017-08-24 | Ｐｅｄｆ由来短ペプチドを含む組成物およびその使用 |
| JP2022155973A Pending JP2022185042A (ja) | 2016-10-07 | 2022-09-29 | Ｐｅｄｆ由来短ペプチドを含む組成物およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022155973A Pending JP2022185042A (ja) | 2016-10-07 | 2022-09-29 | Ｐｅｄｆ由来短ペプチドを含む組成物およびその使用 |
Country Status (10)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7494122B2 (ja) * | 2018-04-08 | 2024-06-03 | ブリム バイオテクノロジー インク | 変形性関節症の治療におけるｐｅｄｆ由来短鎖ペプチドの使用 |
| US20210244791A1 (en) * | 2018-04-08 | 2021-08-12 | Brim Biotechnology, Inc. | Application of pedf-derived short peptides in tendon healing |
| JP2021523116A (ja) * | 2018-05-04 | 2021-09-02 | ブリム バイオテクノロジー インクＢｒｉｍ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ， Ｉｎｃ． | マイボーム腺再生を促進するためのｐｅｄｆ由来ペプチドおよびその使用 |
| CN111632128B (zh) * | 2019-02-14 | 2022-07-05 | 三凡生技研发股份有限公司 | 短链胜肽组合物在预防或治疗干眼症的应用 |
| TWI759610B (zh) * | 2019-06-27 | 2022-04-01 | 晶碩光學股份有限公司 | 具有角膜修護功能的眼用產品 |
| TWI744683B (zh) * | 2019-08-27 | 2021-11-01 | 台灣基督長老教會馬偕醫療財團法人馬偕紀念醫院 | 短合成胜肽及其治療視網膜退化性疾病和/或組織損傷的用途 |
| US12221494B2 (en) * | 2019-08-27 | 2025-02-11 | Mackay Memorial Hospital | Short synthetic peptides and their uses for treating retinal degenerative diseases and/or tissue injuries |
| US20240052003A1 (en) * | 2019-10-06 | 2024-02-15 | Brim Biotechnology, Inc. | Compositions comprising pedf-derived short peptides (pdsp) and uses thereof |
| CN112206312A (zh) * | 2020-11-19 | 2021-01-12 | 北京大学第三医院（北京大学第三临床医学院） | 一种包含pedf的用于治疗干眼的药物组合物 |
| CN115364199A (zh) * | 2021-05-19 | 2022-11-22 | 远大医药（中国）有限公司 | 包含pedf衍生的短肽的组合物及其制备方法和用途 |
| JP2025519647A (ja) * | 2022-06-13 | 2025-06-26 | ブリム バイオテクノロジー インク | ドライアイ疾患の治療のためのｐｅｄｆ由来短鎖ペプチドを含む組成物 |
| TW202400628A (zh) * | 2022-06-24 | 2024-01-01 | 全福生物科技股份有限公司 | 用於治療神經營養性角膜炎疾病之包含pedf衍生短肽之組合物 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6451763B1 (en) * | 1992-06-04 | 2002-09-17 | The United States Of America As Represented By The Department Of Health And Human Services | Retinal pigmented epithelium derived neurotrophic factor and methods of use |
| US6797691B1 (en) * | 1997-07-23 | 2004-09-28 | Northwestern University | Methods and compositions for inhibiting angiogenesis |
| JP2007509984A (ja) * | 2003-10-29 | 2007-04-19 | ザ・ジョンズ・ホプキンス・ユニバーシティ | 色素上皮由来因子、その新規な生物活性及びその使用方法 |
| US20050260180A1 (en) * | 2004-03-12 | 2005-11-24 | Genvec, Inc. | Materials and methods for treating vascular leakage in the eye |
| WO2007095350A2 (en) * | 2006-02-15 | 2007-08-23 | Yale University | Compositions and methods for use of pigment epithelial derived factor (pedf) peptide fragments |
| BRPI0911501A2 (pt) * | 2008-04-29 | 2015-07-28 | Monsanto Technology Llc | Genes e usos para melhoramento de plantas. |
| WO2011044216A1 (en) * | 2009-10-08 | 2011-04-14 | Neurotech Usa, Inc. | Use of pedf in an encapsulated cell-based delivery system |
| EP2508196B1 (en) * | 2011-03-23 | 2018-09-26 | Mackay Memorial Hospital | Use of PEDF-derived polypeptides for promoting stem cells proliferation and wound healing |
| TWI554521B (zh) * | 2011-10-19 | 2016-10-21 | 台灣基督長老教會馬偕醫療財團法人馬偕紀念醫院 | 色素上皮衍生因子衍生之多胜肽於治療禿髮和／或毛髮脫色之用途 |
| EP2882772B1 (en) * | 2012-08-09 | 2017-12-20 | Mackay Memorial Hospital | Use of pedf-derived polypeptides for promoting muscle or tendon regeneration or arteriogenesis |
| EP2897976B1 (en) * | 2012-09-19 | 2017-08-09 | Mackay Memorial Hospital | Use of pedf-derived peptides for preventing and/or ameliorating skin aging |
| EA030022B1 (ru) * | 2012-09-20 | 2018-06-29 | Маккей Мемориал Хоспитал | Применение pedf-производных полипептидов для лечения остеоартрита |
| WO2015038891A2 (en) * | 2013-09-13 | 2015-03-19 | The Penn State Research Foundation | Functional peptide analogs of pedf |
-
2017
- 2017-08-24 KR KR1020237039829A patent/KR20230169375A/ko active Pending
- 2017-08-24 EA EA201990885A patent/EA037698B1/ru unknown
- 2017-08-24 JP JP2019540514A patent/JP7573967B2/ja active Active
- 2017-08-24 US US16/340,113 patent/US11760784B2/en active Active
- 2017-08-24 WO PCT/US2017/048340 patent/WO2018067244A1/en unknown
- 2017-08-24 CN CN201780075291.2A patent/CN110312732A/zh active Pending
- 2017-08-24 IL IL265796A patent/IL265796B2/en unknown
- 2017-08-24 KR KR1020197012272A patent/KR20190066030A/ko not_active Ceased
- 2017-08-24 EP EP17858860.4A patent/EP3596104A4/en active Pending
- 2017-08-24 AU AU2017340245A patent/AU2017340245B2/en active Active
- 2017-09-29 TW TW106133749A patent/TWI878203B/zh active
- 2017-10-07 WO PCT/US2017/042474 patent/WO2018067217A2/en active Application Filing
-
2022
- 2022-06-28 AU AU2022204557A patent/AU2022204557A1/en not_active Abandoned
- 2022-09-29 JP JP2022155973A patent/JP2022185042A/ja active Pending