JP2019533645A5 - - Google Patents

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Publication number
JP2019533645A5
JP2019533645A5 JP2019514781A JP2019514781A JP2019533645A5 JP 2019533645 A5 JP2019533645 A5 JP 2019533645A5 JP 2019514781 A JP2019514781 A JP 2019514781A JP 2019514781 A JP2019514781 A JP 2019514781A JP 2019533645 A5 JP2019533645 A5 JP 2019533645A5
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JP
Japan
Prior art keywords
protein
agents
protein nanocage
nanocage
agent
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Pending
Application number
JP2019514781A
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English (en)
Japanese (ja)
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JP2019533645A (ja
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Publication date
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Priority claimed from PCT/US2017/052079 external-priority patent/WO2018053434A1/en
Publication of JP2019533645A publication Critical patent/JP2019533645A/ja
Publication of JP2019533645A5 publication Critical patent/JP2019533645A5/ja
Pending legal-status Critical Current

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JP2019514781A 2016-09-16 2017-09-18 標的組織および細胞内送達のための増大した粘膜浸透のタンパク質ナノケージ Pending JP2019533645A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662395852P 2016-09-16 2016-09-16
US62/395,852 2016-09-16
PCT/US2017/052079 WO2018053434A1 (en) 2016-09-16 2017-09-18 Protein nanocages with enhanced mucus penetration for targeted tissue and intracellular delivery

Publications (2)

Publication Number Publication Date
JP2019533645A JP2019533645A (ja) 2019-11-21
JP2019533645A5 true JP2019533645A5 (enExample) 2020-10-08

Family

ID=60002019

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019514781A Pending JP2019533645A (ja) 2016-09-16 2017-09-18 標的組織および細胞内送達のための増大した粘膜浸透のタンパク質ナノケージ

Country Status (4)

Country Link
US (1) US11090391B2 (enExample)
EP (1) EP3512563A1 (enExample)
JP (1) JP2019533645A (enExample)
WO (1) WO2018053434A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108503704A (zh) * 2017-02-27 2018-09-07 昆山新蕴达生物科技有限公司 穿越血脑屏障的纳米药物载体
CN112367974A (zh) * 2018-05-15 2021-02-12 DNALite治疗学公司 粘液穿透肽、递送媒介和治疗方法
US20210402000A1 (en) * 2018-10-10 2021-12-30 University Of Washington High-polymer-density bioconjugate compositions and related methods
WO2020180144A1 (ko) * 2019-03-07 2020-09-10 경북대학교 산학협력단 트레일 트라이머와 암표적 펩타이드를 멀티디스플레이하는 페리틴 나노케이지 및 이의 항암제로서의 용도
JP7600993B2 (ja) * 2019-09-05 2024-12-17 味の素株式会社 ペプチド内包フェリチン
JP7541390B2 (ja) * 2019-11-01 2024-08-28 セレメディー カンパニー，リミテッド 免疫チェックポイント分子と結合可能な分子が融合したタンパク質およびその用途
JP7345941B2 (ja) * 2019-11-01 2023-09-19 セレメディー カンパニー，リミテッド 疾患抗原が融合したタンパク質およびその用途
EP4053157A4 (en) * 2019-11-01 2023-12-27 Cellemedy Co., Ltd PROTEIN FUSED WITH A DISEASE ANTIGEN AND CORRESPONDING USE
KR102658825B1 (ko) * 2020-10-23 2024-04-19 경북대학교 산학협력단 Pd-l1 결합 펩타이드 1을 융합한 페리틴 나노케이지 및 이의 항암면역치료제로서의 용도
CN112972421B (zh) * 2021-02-26 2022-04-08 清华大学 基于多正电荷蛋白的纳米药物系统、其制备方法及应用
CN115160559B (zh) * 2021-04-02 2024-02-02 杭州宜生医药科技发展有限公司 一种peg化雷帕霉素化合物及其制备方法与应用
WO2024228598A1 (ko) * 2023-05-04 2024-11-07 경북대학교 산학협력단 Lag3 결합 펩타이드를 융합한 페리틴 나노케이지 및 이의 항암면역치료제로서의 용도
CN119326734B (zh) * 2024-12-17 2025-06-06 浙江大学 一种铁蛋白纳米颗粒及其药物递送系统的组装方法和应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034506A (en) 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US6699475B1 (en) 1987-09-02 2004-03-02 Therion Biologics Corporation Recombinant pox virus for immunization against tumor-associated antigens
KR920003787B1 (ko) 1990-03-05 1992-05-14 한국과학기술 연구원 신규 플라스미드 제조 및 그를 함유한 균주를 배양하여 아이 지 에프-1(igf-1)을 생산하는 방법
US5571711A (en) 1993-06-17 1996-11-05 Ludwig Institute For Cancer Research Isolated nucleic acid molecules coding for BAGE tumor rejection antigen precursors
US5821122A (en) 1995-06-07 1998-10-13 Inserm (Institute Nat'l De La Sante Et De La Recherche . .) Isolated nucleic acid molecules, peptides which form complexes with MHC molecule HLA-A2 and uses thereof
WO2000011947A1 (en) 1998-08-28 2000-03-09 Uropath Pty. Ltd. Method of diagnosis of prostate cancer
ATE328280T1 (de) 1999-02-26 2006-06-15 Pacific Northwest Res Inst Verfahren und zusammensetzungen zur karzinomdiagnose
US6673545B2 (en) 2000-07-28 2004-01-06 Incyte Corporation Prostate cancer markers
IL149820A0 (en) 2002-05-23 2002-11-10 Curetech Ltd Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency
DE60334303D1 (de) 2002-07-03 2010-11-04 Tasuku Honjo Immunpotenzierende zusammensetzungen
ES2367430T3 (es) 2002-12-23 2011-11-03 Wyeth Llc Anticuerpos contra pd-1 y sus usos.
US7563869B2 (en) 2003-01-23 2009-07-21 Ono Pharmaceutical Co., Ltd. Substance specific to human PD-1
EP3530736A3 (en) 2005-05-09 2019-11-06 ONO Pharmaceutical Co., Ltd. Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics
DK1907000T4 (da) 2005-06-08 2020-03-30 The President And Fellows Of Harvard College Fremgangsmåder og sammensætninger til behandling af persisterende HIV-infektioner ved hæmning af reaktionsvejen for programmeret celledød 1 (PD-1).
KR101704734B1 (ko) 2005-07-01 2017-02-09 이. 알. 스퀴부 앤드 선즈, 엘.엘.씨. 예정 사멸 리간드 1 (피디-엘1)에 대한 인간 모노클로날 항체
WO2008048288A2 (en) * 2005-11-09 2008-04-24 Montana State University Novel nanoparticles and use thereof
WO2007114946A2 (en) 2006-04-04 2007-10-11 The Regents Of The University Of California Acid-sensitive linkers for drug delivery
CA2673870A1 (en) 2006-12-27 2008-07-10 Emory University Compositions and methods for the treatment of infections and tumors
US20090028857A1 (en) 2007-07-23 2009-01-29 Cell Genesys, Inc. Pd-1 antibodies in combination with a cytokine-secreting cell and methods of use thereof
AR069747A1 (es) 2007-11-30 2010-02-17 Medarex Inc Conjugado anticuerpo monoclonal anti-b7h4- farmaco y metodos de utilizacion
JPWO2010029947A1 (ja) * 2008-09-09 2012-02-02 国立大学法人京都大学 造影剤組成物及びその製造方法
CA2828253C (en) * 2011-02-25 2016-10-18 South Dakota State University Polymer conjugated protein micelles
CA2859046C (en) * 2011-12-14 2019-10-22 The Johns Hopkins University Nanoparticles with enhanced mucosal penetration or decreased inflammation
WO2014031727A1 (en) 2012-08-21 2014-02-27 Brown University Ferritin-based tumor targeting agent, and imaging and treatment methods
EP3197920B1 (en) 2014-09-25 2021-01-13 Nanyang Technological University Targeting of melanocytes for delivering therapeutic or diagnostic agents using protein nanocages

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