JP2019530878A5 - - Google Patents
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- JP2019530878A5 JP2019530878A5 JP2019519961A JP2019519961A JP2019530878A5 JP 2019530878 A5 JP2019530878 A5 JP 2019530878A5 JP 2019519961 A JP2019519961 A JP 2019519961A JP 2019519961 A JP2019519961 A JP 2019519961A JP 2019530878 A5 JP2019530878 A5 JP 2019530878A5
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- JP
- Japan
- Prior art keywords
- patient
- biomarker
- days
- label
- c11orf74
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000000034 method Methods 0.000 claims 18
- 239000000090 biomarker Substances 0.000 claims 11
- 230000014509 gene expression Effects 0.000 claims 7
- 108010009992 CD163 antigen Proteins 0.000 claims 4
- 101710205374 Extracellular elastase Proteins 0.000 claims 4
- 101001046870 Homo sapiens Hypoxia-inducible factor 1-alpha Proteins 0.000 claims 4
- 101000999365 Homo sapiens Intraflagellar transport-associated protein Proteins 0.000 claims 4
- 101001018028 Homo sapiens Lymphocyte antigen 86 Proteins 0.000 claims 4
- 101000929203 Homo sapiens Neutrophil defensin 4 Proteins 0.000 claims 4
- 101000579484 Homo sapiens Period circadian protein homolog 1 Proteins 0.000 claims 4
- 101001126582 Homo sapiens Post-GPI attachment to proteins factor 3 Proteins 0.000 claims 4
- 102100022875 Hypoxia-inducible factor 1-alpha Human genes 0.000 claims 4
- 102100036484 Intraflagellar transport-associated protein Human genes 0.000 claims 4
- 102100033485 Lymphocyte antigen 86 Human genes 0.000 claims 4
- 102100036348 Neutrophil defensin 4 Human genes 0.000 claims 4
- 102100028293 Period circadian protein homolog 1 Human genes 0.000 claims 4
- 102100021269 Regulator of G-protein signaling 1 Human genes 0.000 claims 4
- 101710140408 Regulator of G-protein signaling 1 Proteins 0.000 claims 4
- 102100025831 Scavenger receptor cysteine-rich type 1 protein M130 Human genes 0.000 claims 4
- 102100023843 Selenoprotein P Human genes 0.000 claims 4
- 101000944277 Homo sapiens Inward rectifier potassium channel 2 Proteins 0.000 claims 3
- 102100033114 Inward rectifier potassium channel 2 Human genes 0.000 claims 3
- 206010040047 Sepsis Diseases 0.000 claims 3
- 239000012472 biological sample Substances 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 239000000523 sample Substances 0.000 claims 3
- -1 CIT Proteins 0.000 claims 2
- 238000010240 RT-PCR analysis Methods 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 208000014674 injury Diseases 0.000 claims 2
- 238000003752 polymerase chain reaction Methods 0.000 claims 2
- 101150068759 KCNJ2 gene Proteins 0.000 claims 1
- 238000000636 Northern blotting Methods 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- 230000003321 amplification Effects 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 230000006378 damage Effects 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 238000010195 expression analysis Methods 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- 238000011901 isothermal amplification Methods 0.000 claims 1
- 238000010208 microarray analysis Methods 0.000 claims 1
- 238000003199 nucleic acid amplification method Methods 0.000 claims 1
- 235000002020 sage Nutrition 0.000 claims 1
- 230000008733 trauma Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022110659A JP2022153436A (ja) | 2016-06-26 | 2022-07-08 | 重篤患者における死亡率の予後診断に使用するためのバイオマーカー |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662354789P | 2016-06-26 | 2016-06-26 | |
| US62/354,789 | 2016-06-26 | ||
| PCT/US2017/029468 WO2018004806A1 (en) | 2016-06-26 | 2017-04-25 | Biomarkers for use in prognosis of mortality in critically ill patients |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022110659A Division JP2022153436A (ja) | 2016-06-26 | 2022-07-08 | 重篤患者における死亡率の予後診断に使用するためのバイオマーカー |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019530878A JP2019530878A (ja) | 2019-10-24 |
| JP2019530878A5 true JP2019530878A5 (https=) | 2020-06-11 |
Family
ID=60786346
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019519961A Pending JP2019530878A (ja) | 2016-06-26 | 2017-04-25 | 重篤患者における死亡率の予後診断に使用するためのバイオマーカー |
| JP2022110659A Pending JP2022153436A (ja) | 2016-06-26 | 2022-07-08 | 重篤患者における死亡率の予後診断に使用するためのバイオマーカー |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022110659A Pending JP2022153436A (ja) | 2016-06-26 | 2022-07-08 | 重篤患者における死亡率の予後診断に使用するためのバイオマーカー |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US10344332B2 (https=) |
| EP (1) | EP3475473A4 (https=) |
| JP (2) | JP2019530878A (https=) |
| CN (2) | CN109451744B (https=) |
| AU (2) | AU2017289600A1 (https=) |
| CA (1) | CA3024724A1 (https=) |
| WO (1) | WO2018004806A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109451744B (zh) * | 2016-06-26 | 2022-08-05 | 斯坦福大学托管董事会 | 用于危重患者的死亡预后的生物标志物 |
| WO2018140256A1 (en) | 2017-01-17 | 2018-08-02 | Duke University | Gene expression signatures useful to predict or diagnose sepsis and methods of using the same |
| EP3759235B1 (en) | 2018-02-27 | 2025-02-19 | The Board Of Trustees Of The Leland Stanford Junior University | Classifier for identification of robust sepsis subtypes |
| AU2020244763A1 (en) * | 2019-03-22 | 2021-09-30 | Inflammatix, Inc. | Systems and methods for deriving and optimizing classifiers from multiple datasets |
| WO2020223257A1 (en) * | 2019-04-28 | 2020-11-05 | Visby Medical, Inc. | Molecular diagnostic devices with digital detection capability and wireless connectivity |
| CN114585923A (zh) * | 2019-10-28 | 2022-06-03 | 豪夫迈·罗氏有限公司 | 脓毒症管理 |
| US20230374589A1 (en) * | 2020-04-29 | 2023-11-23 | Inflammatix, Inc. | Determining mortality risk of subjects with viral infections |
| EP4217067A4 (en) * | 2020-09-25 | 2025-02-12 | The Board Of Trustees Of The Leland Stanford Junior University | Method for determining a virally-infected subject's risk of developing severe symptoms |
| CN114606308A (zh) * | 2022-01-26 | 2022-06-10 | 江门市中心医院 | 脓毒症ards的预后与治疗标志物 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5245615A (en) | 1991-06-06 | 1993-09-14 | International Business Machines Corporation | Diagnostic system and interface for a personal computer |
| IL127936A (en) | 1996-07-12 | 2004-05-12 | First Opinion Corp | Computerized medical diagnostic system |
| CA2505843A1 (en) * | 2002-11-12 | 2004-05-27 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
| US20050196817A1 (en) * | 2004-01-20 | 2005-09-08 | Molecular Staging Inc. | Biomarkers for sepsis |
| CN101208602A (zh) * | 2005-04-15 | 2008-06-25 | 贝克顿迪金森公司 | 脓毒症的诊断 |
| DE102005050933A1 (de) * | 2005-10-21 | 2007-04-26 | Justus-Liebig-Universität Giessen | Erfindung betreffend Expressionsprofile zur Vorhersage von septischen Zuständen |
| ES2349691T3 (es) * | 2005-11-25 | 2011-01-10 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | PROCEDIMIENTO PARA DETECTAR O MONITORIZAR LA SEPTICEMIA ANALIZANDO NIVELES DE EXPRESIÓN DE ARNm DE CITOCINAS. |
| EP2388594A1 (en) * | 2010-05-17 | 2011-11-23 | Roche Diagnostics GmbH | GDF-15 based means and methods for survival and recovery prediction in acute inflammation |
| US20110312521A1 (en) * | 2010-06-17 | 2011-12-22 | Baylor Research Institute | Genomic Transcriptional Analysis as a Tool for Identification of Pathogenic Diseases |
| US20120034214A1 (en) * | 2010-07-22 | 2012-02-09 | Isis Innovation Limited | Methods and kits for determining the prognosis of pulmonary sarcoidosis |
| JP6018923B2 (ja) * | 2011-01-11 | 2016-11-02 | 株式会社Ｌｓｉメディエンス | 敗血症の予後の予測方法 |
| EP2678448A4 (en) * | 2011-02-22 | 2014-10-01 | Caris Life Sciences Luxembourg Holdings S A R L | CIRCULATING BIOMARKERS |
| US20150024969A1 (en) * | 2011-09-12 | 2015-01-22 | The Children's Mercy Hospital | Sepsis prognosis biomarkers |
| AU2014284124B2 (en) | 2013-06-20 | 2020-03-12 | Immunexpress Pty Ltd | Biomarker identification |
| US20170073734A1 (en) * | 2014-03-14 | 2017-03-16 | Robert E. W. Hancock | Diagnostic for Sepsis |
| CN109451744B (zh) * | 2016-06-26 | 2022-08-05 | 斯坦福大学托管董事会 | 用于危重患者的死亡预后的生物标志物 |
-
2017
- 2017-04-25 CN CN201780039163.2A patent/CN109451744B/zh active Active
- 2017-04-25 AU AU2017289600A patent/AU2017289600A1/en not_active Abandoned
- 2017-04-25 EP EP17820714.8A patent/EP3475473A4/en not_active Withdrawn
- 2017-04-25 JP JP2019519961A patent/JP2019530878A/ja active Pending
- 2017-04-25 CN CN202210792075.2A patent/CN115161389A/zh active Pending
- 2017-04-25 US US15/553,152 patent/US10344332B2/en active Active
- 2017-04-25 WO PCT/US2017/029468 patent/WO2018004806A1/en not_active Ceased
- 2017-04-25 CA CA3024724A patent/CA3024724A1/en active Pending
-
2018
- 2018-12-11 US US16/216,846 patent/US11608531B2/en active Active
-
2019
- 2019-05-20 US US16/417,358 patent/US10648033B2/en not_active Expired - Fee Related
-
2022
- 2022-07-08 JP JP2022110659A patent/JP2022153436A/ja active Pending
- 2022-08-01 AU AU2022211785A patent/AU2022211785A1/en not_active Abandoned
-
2023
- 2023-02-08 US US18/107,477 patent/US20240011096A1/en not_active Abandoned
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