|
NL7409399A
(nl)
|
1973-07-19 |
1975-01-21 |
Rhone Poulenc Sa |
Werkwijze ter bereiding van thermostabiele har- sen en voorwerpen geheel of gedeeltelijk be- staande uit deze harsen.
|
|
US4471057A
(en)
|
1981-06-30 |
1984-09-11 |
The Wistar Institute |
Detection of colorectal carcinoma
|
|
DK17885D0
(da)
|
1985-01-14 |
1985-01-14 |
Karlsson Karl Anders |
Antiviralt middel
|
|
US4876199A
(en)
|
1985-04-04 |
1989-10-24 |
Fred Hutchinson Cancer Research Center |
Hybridomas producing monoclonal antibodies to mono-, di-, and trifucosylated type 2 chain
|
|
US4851511A
(en)
|
1986-01-30 |
1989-07-25 |
Fred Hutchinson Cancer Research Center |
Monoclonal antibody that specifically binds to disialosyl Lea
|
|
US4925796A
(en)
|
1986-03-07 |
1990-05-15 |
Massachusetts Institute Of Technology |
Method for enhancing glycoprotein stability
|
|
EP0249008B1
(de)
|
1986-05-09 |
1993-09-15 |
Pulverer, Gerhard, Prof. Dr.Dr.h.c. |
Verwendung von spezifischen Monosacchariden zur Herstellung eines Arzneimittels zur Verhinderung von Metastasen maligner Tumore
|
|
US5538724A
(en)
|
1987-08-11 |
1996-07-23 |
The Board Of Trustees For The Leland Stanford Junior Univ. |
Method of control leukocyte extravasation
|
|
US5079353A
(en)
|
1987-12-02 |
1992-01-07 |
Chembiomed, Ltd. |
Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
|
|
US5632991A
(en)
|
1988-11-14 |
1997-05-27 |
Brigham & Women's Hospital |
Antibodies specific for E-selectin and the uses thereof
|
|
EP0381310A1
(en)
|
1989-01-30 |
1990-08-08 |
The Biomembrane Institute |
Monoclonal antibodies directed to tumor-associated gangliosides and fucogangliosides and method for production thereof
|
|
US5464778A
(en)
|
1989-03-08 |
1995-11-07 |
Board Of Regents Of The University Of Oklahoma |
Glycoprotein ligand for P-selectin and methods of use thereof
|
|
US5272263A
(en)
|
1989-04-28 |
1993-12-21 |
Biogen, Inc. |
DNA sequences encoding vascular cell adhesion molecules (VCAMS)
|
|
DE69021456T2
(de)
|
1989-05-23 |
1996-02-15 |
Otsuka Pharma Co Ltd |
Monoklonale Antikörper gegen aktivierte endotheliale Zellen.
|
|
US6033665A
(en)
|
1989-09-27 |
2000-03-07 |
Elan Pharmaceuticals, Inc. |
Compositions and methods for modulating leukocyte adhesion to brain endothelial cells
|
|
US6001988A
(en)
|
1990-06-11 |
1999-12-14 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands to lectins
|
|
US6280932B1
(en)
|
1990-06-11 |
2001-08-28 |
Gilead Sciences, Inc. |
High affinity nucleic acid ligands to lectins
|
|
US5576305A
(en)
|
1990-06-15 |
1996-11-19 |
Cytel Corporation |
Intercellular adhesion mediators
|
|
AU8007791A
(en)
|
1990-06-15 |
1992-01-07 |
Cytel Corporation |
Intercellular adhesion mediators
|
|
US5753631A
(en)
|
1990-06-15 |
1998-05-19 |
Cytel Corporation |
Intercellular adhesion mediators
|
|
US6391857B1
(en)
|
1990-06-18 |
2002-05-21 |
Stanford University |
Methods and compositions for endothelial binding
|
|
US6387884B1
(en)
|
1990-06-18 |
2002-05-14 |
Stanford University |
Leukocyte homing modulation
|
|
WO1992001718A2
(en)
|
1990-07-17 |
1992-02-06 |
Board Of Regents Of The University Of Oklahoma |
Functionally active selectin-derived peptides and ligand for gmp-140
|
|
US5211937A
(en)
|
1990-07-30 |
1993-05-18 |
Glycomed Incorporated |
Method of determining a site of inflammation utilizing elam-1 ligands
|
|
US5648344A
(en)
|
1990-07-30 |
1997-07-15 |
Glycomed Incorporated |
Methods of treating inflammation using selection binding compounds
|
|
US5143712A
(en)
|
1990-07-30 |
1992-09-01 |
Glycomed Incorporated |
Method of determining a site of inflammation utilizing elam-1 ligands
|
|
US5789573A
(en)
|
1990-08-14 |
1998-08-04 |
Isis Pharmaceuticals, Inc. |
Antisense inhibition of ICAM-1, E-selectin, and CMV IE1/IE2
|
|
NZ240316A
(en)
|
1990-10-25 |
1996-12-20 |
Univ Michigan |
Compound for treating disease mediated by the elaboration of elam-1 on endothelial cells
|
|
IE914075A1
(en)
|
1990-11-23 |
1992-06-03 |
Gen Hospital Corp |
Inhibition of cell adhesion protein-carbohydrate¹interactions
|
|
US5151360A
(en)
|
1990-12-31 |
1992-09-29 |
Biomembrane Institute |
Effect of n,n,n-trimethylsphingosine on protein kinase-c activity, melanoma cell growth in vitro, metastatic potential in vivo and human platelet aggregation
|
|
US6309639B1
(en)
|
1991-02-05 |
2001-10-30 |
The Board Of Regents Of The University Of Oklahoma |
Method for inhibiting an inflammatory response using antibodies to P-selectin glycoprotein ligand
|
|
US6124267A
(en)
|
1991-02-05 |
2000-09-26 |
Southpac Trust Internationals, Inc. |
O-glycan inhibitors of selectin mediated inflammation derived from PSGL-1
|
|
US6121233A
(en)
|
1991-04-19 |
2000-09-19 |
John L. Magnani |
Methods for the inhibition of cancer metastasis mediated by endothelial adhesion molecules
|
|
ATE245696T1
(de)
|
1991-05-06 |
2003-08-15 |
Genentech Inc |
Ein selectin ligand
|
|
US5318890A
(en)
|
1991-05-06 |
1994-06-07 |
The Regents Of The University Of California |
Assays for inhibitors of leukocyte adhesion
|
|
US5580858A
(en)
|
1991-06-10 |
1996-12-03 |
Alberta Research Council |
Immunosuppressive and tolerogenic modified Lewisx compounds
|
|
US5646123A
(en)
|
1991-06-10 |
1997-07-08 |
Alberta Research Council |
Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen
|
|
US5352670A
(en)
|
1991-06-10 |
1994-10-04 |
Alberta Research Council |
Methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides
|
|
CA2118695A1
(en)
|
1991-09-10 |
1993-03-18 |
George A. Heavner |
Peptide inhibitors of inflammation mediated by selectins
|
|
US5268364A
(en)
|
1991-12-12 |
1993-12-07 |
The Biomembrane Institute |
Method for inhibiting selectin-dependent adhesion of leukocytes and platelets by O-glycosylation modification
|
|
AU3914393A
(en)
|
1991-12-18 |
1994-03-15 |
Board Of Regents Of The University Of Oklahoma, The |
Peptide inhibitors of inflammation mediated by selectins
|
|
US5643873A
(en)
|
1992-05-06 |
1997-07-01 |
Affymax Technologies N.V. |
Peptides and compounds that bind selectins including endothelial leukocyte adhesion molecule 1
|
|
US5591835A
(en)
|
1992-06-29 |
1997-01-07 |
Glycomed Incorporated |
Substituted lactose derivatives
|
|
CA2100412A1
(en)
|
1992-07-15 |
1994-01-16 |
Yutaka Yamada |
Glycolipid derivatives
|
|
US5753617A
(en)
|
1992-09-08 |
1998-05-19 |
Centocor, Inc. |
Peptide inhibitors of cellular adhesion
|
|
US5519008A
(en)
|
1992-09-10 |
1996-05-21 |
Glycomed Incorporated |
Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (E-selectin) and LECAM-1 (L-selectin)
|
|
US5695752A
(en)
|
1992-09-11 |
1997-12-09 |
The Regents Of The University Of California |
Treating inflammation via the administration of specific sulfatase enzymes and/or sulfation inhibitor
|
|
WO1994006442A1
(en)
|
1992-09-11 |
1994-03-31 |
The Regents Of The University Of California |
Sulfated ligands for l-selectins and use of chlorates and or sulfatases for the treatment of inflammation
|
|
US5843707A
(en)
|
1992-10-23 |
1998-12-01 |
Genetics Institute, Inc. |
Nucleic acid encoding a novel P-selectin ligand protein
|
|
US6277975B1
(en)
|
1992-10-23 |
2001-08-21 |
Genetics Institute, Inc. |
Fusions of P-selectin ligand protein and polynucleotides encoding same
|
|
EP0601417A3
(de)
|
1992-12-11 |
1998-07-01 |
Hoechst Aktiengesellschaft |
Physiologisch verträglicher und physiologisch abbaubarer, Kohlenhydratrezeptorblocker auf Polymerbasis, ein Verfahren zu seiner Herstellung und seine Verwendung
|
|
US5710123A
(en)
|
1992-12-18 |
1998-01-20 |
Centocor, Inc. |
Peptide inhibitors of selectin binding
|
|
AU678429B2
(en)
|
1992-12-29 |
1997-05-29 |
Genentech Inc. |
Treatment of inflammatory bowel disease with IFN-gamma inhibitors
|
|
US5412123A
(en)
|
1993-02-08 |
1995-05-02 |
Glycomed Incorporated |
Anthraquinone and anthracene derivatives as inhibitors of the cell-adhesion molecules of the immune system
|
|
JP2716657B2
(ja)
|
1993-02-26 |
1998-02-18 |
株式会社ディ・ディ・エス研究所 |
接着分子ｅｌａｍ‐１に特異的結合能を有する化合物
|
|
WO1994020514A1
(fr)
|
1993-03-04 |
1994-09-15 |
Mect Corporation |
Compose associe au systeme de lewis, procede d'obtention de ce compose et anti-inflammatoire
|
|
US5527890A
(en)
|
1993-04-16 |
1996-06-18 |
Glycomed Incorporated |
Derivatives of triterpenoid acids and uses thereof
|
|
EP0700301B1
(en)
|
1993-05-05 |
1999-09-01 |
Affymax Technologies N.V. |
Peptides and compounds that bind to elam-1
|
|
CA2162478A1
(en)
|
1993-05-14 |
1994-11-24 |
Shawn A. Defrees |
Sialyl lex analogues as inhibitors of cellular adhesion
|
|
US5811404A
(en)
|
1993-05-14 |
1998-09-22 |
Cytel Corporation |
Sialyl Lex analogues as inhibitors of cellular adhesion
|
|
US5854218A
(en)
|
1993-05-14 |
1998-12-29 |
Cytel Corporation |
Sialyl Lex analogues as inhibitors of cellular adhesion
|
|
US5527785A
(en)
|
1993-05-14 |
1996-06-18 |
The Regents Of The University Of California |
Selectin receptor modulating compositions
|
|
SE9301677L
(sv)
|
1993-05-14 |
1994-11-18 |
Kurt G I Nilsson |
Syntesmetod
|
|
DK0730608T3
(da)
|
1993-05-17 |
2002-07-22 |
Avant Immunotherapeutics Inc |
Præparater omfattende komplementrelaterede proteiner og carbohydrater og fremgangsmåder til fremstilling og anvendelse af præparaterne
|
|
US5976540A
(en)
|
1993-05-17 |
1999-11-02 |
T Cell Sciences, Inc. |
Compositions comprising complement related proteins and carbohydrates, and methods for producing and using said compositions
|
|
US5856300A
(en)
|
1994-05-12 |
1999-01-05 |
T Cell Sciences, Inc. |
Compositions comprising complement related proteins and carbohydrates, and methods for producing and using said compositions
|
|
US5646248A
(en)
|
1993-06-08 |
1997-07-08 |
La Jolla Cancer Research Foundation |
E-selection binding soluble lamp-1 polypeptide
|
|
US5789385A
(en)
|
1993-06-16 |
1998-08-04 |
Glycomed Incorporated |
Sialyl Lewisx mimetics containing phenyl backbones
|
|
US5658880A
(en)
|
1993-06-16 |
1997-08-19 |
Glycomed Incorporated |
Sialic acid/fucose based medicaments
|
|
US5750508A
(en)
|
1993-06-16 |
1998-05-12 |
Glycomed Incorporated |
Sialic acid/fucose based medicaments
|
|
US5837689A
(en)
|
1993-06-16 |
1998-11-17 |
Glycomed Incorporated |
Sialyl lewis-x mimetics containing naphthyl backbones
|
|
US5679321A
(en)
|
1993-06-17 |
1997-10-21 |
Glycomed Incorporated |
Sialic acid/fucose based medicaments
|
|
DK76193D0
(da)
|
1993-06-25 |
1993-06-25 |
Astra Ab |
Kulhydratderivater
|
|
US5559103A
(en)
|
1993-07-21 |
1996-09-24 |
Cytel Corporation |
Bivalent sialyl X saccharides
|
|
US5508387A
(en)
|
1993-08-04 |
1996-04-16 |
Glycomed Incorporated |
Selectin binding glycopeptides
|
|
WO1995005830A1
(en)
|
1993-08-20 |
1995-03-02 |
The Regents Of The University Of California |
Polyanion anti-inflammatory agents
|
|
US5464815A
(en)
|
1993-09-08 |
1995-11-07 |
Genentech, Inc. |
Inhibition of heparin-binding
|
|
CA2173990A1
(en)
|
1993-10-12 |
1995-04-20 |
Narasinga Rao |
A library of glyco-peptides useful for identification of cell adhesion inhibitors
|
|
US5783693A
(en)
|
1993-11-19 |
1998-07-21 |
The Regents Of The University Of California |
Methods for synthesizing sulfated disaccharide inhibitors of selectins
|
|
WO1995014787A1
(en)
|
1993-11-22 |
1995-06-01 |
Centocor, Inc. |
Peptide inhibitors of selecting binding
|
|
US5663151A
(en)
|
1994-03-04 |
1997-09-02 |
Bristol-Myers Squibb Company |
Sulfated α-glycolipid derivatives as cell adhesion inhibitors
|
|
DE4408248A1
(de)
|
1994-03-11 |
1995-09-14 |
Hoechst Ag |
Physiologisch verträgliche und physiologisch abbaubare Kohlenhydrat-Mimetika, ein Verfahren zur Herstellung und ihre Verwendung
|
|
EP0671409A3
(de)
|
1994-03-11 |
1996-06-12 |
Hoechst Ag |
Malonsäurederivate mit antiadhäsiven Eigenschaften.
|
|
US5444050A
(en)
|
1994-04-29 |
1995-08-22 |
Texas Biotechnology Corporation |
Binding of E-selectin or P-selectin to sialyl Lewisx or sialyl-Lewisa
|
|
HUT77345A
(hu)
|
1994-04-29 |
1998-03-30 |
Texas Biotechnology Corporation |
E-szelektin, P-szelektin vagy L-szelektin szialil-Lewis x-hez vagy szialil-Lewis a-hoz kapcsolódását gátló mannopiranoziloxi-bifenil származékok és ezeket tartalmazó gyógyszerkészítmények
|
|
US5486536A
(en)
|
1994-08-15 |
1996-01-23 |
The Regents Of The University Of Michigan |
Sulfatides as anti-inflammatory compounds
|
|
JPH0899989A
(ja)
|
1994-09-30 |
1996-04-16 |
Akira Hasegawa |
新規糖脂質誘導体およびその製造用中間体
|
|
DE4436164A1
(de)
|
1994-10-10 |
1996-04-11 |
Hoechst Ag |
Neue Kohlenhydratkonjugate als Inhibitoren der Zelladhäsion
|
|
US5686426A
(en)
|
1994-11-17 |
1997-11-11 |
Bristol-Myers Squibb Company |
Dicarboxymethylated glycolipid derivatives as cell adhesion inhibitors
|
|
US6492332B1
(en)
|
1995-12-12 |
2002-12-10 |
Omeros Corporation |
Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation
|
|
US5639734A
(en)
|
1994-12-20 |
1997-06-17 |
Esko; Jeffrey D. |
Disaccharide inflammation inhibitors and uses thereof
|
|
EP0801071A4
(en)
|
1994-12-28 |
1999-01-13 |
Sumitomo Pharma |
LEWIS DERIVATIVE X AND PRODUCTION METHOD THEREOF
|
|
US20020040008A1
(en)
|
1995-01-24 |
2002-04-04 |
Wagner Denisa D. |
Method for treating and preventing atherosclerosis
|
|
US5527936A
(en)
|
1995-02-17 |
1996-06-18 |
E. I. Du Pont De Nemours And Company |
Hydrosilylation of unsaturated compounds
|
|
GB9504065D0
(en)
|
1995-03-01 |
1995-04-19 |
Pharmacia Spa |
Poly-pyrrolecarboxamidonaphthalenic acid derivatives
|
|
GB9511357D0
(en)
|
1995-06-06 |
1995-08-02 |
Johnson Matthey Plc |
Improved antiviral compounds
|
|
US6506770B1
(en)
|
1996-06-06 |
2003-01-14 |
Anormed, Inc. |
Antiviral compounds
|
|
US5736533A
(en)
|
1995-06-07 |
1998-04-07 |
Neose Technologies, Inc. |
Bacterial inhibition with an oligosaccharide compound
|
|
WO1996040942A1
(en)
|
1995-06-07 |
1996-12-19 |
Cytel Corporation |
Humanized antibodies to e-selectin
|
|
IT1290779B1
(it)
|
1995-06-26 |
1998-12-10 |
Antonio Sacchetti |
Procedimento per il potenziamento delle attivita' terapeutiche di sostanze naturali (vitamine, minerali, erbe, fitopreparati, alimenti)
|
|
JPH11508548A
(ja)
|
1995-06-29 |
1999-07-27 |
ノバルティス・アクチエンゲゼルシャフト |
シアリル−ルイスｘおよびシアリル−ルイスａの模倣物としてのジグリコシル化１，２−ジオール
|
|
US5876715A
(en)
|
1995-08-17 |
1999-03-02 |
The Biomembrane Institute |
Antibodies that bind novel carbohydrate ligands (myelorollins) that cause E-selectin dependent cell rolling, and uses thereof
|
|
DE19532902A1
(de)
|
1995-09-06 |
1997-03-13 |
Hoechst Ag |
Neuartige Glycomimetika als Selektin-Antagonisten und daraus hergestellte entzündungshemmend wirkende Arzneimittel
|
|
DE19537334A1
(de)
|
1995-10-09 |
1997-04-10 |
Hoechst Ag |
Antiadhäsive Piperidin- und Pyrrolidin-Carbonsäuren
|
|
AU7445796A
(en)
|
1995-10-18 |
1997-05-07 |
Cytel Corporation |
Sialyl lex analogues as inhibitors of cellular adhesion
|
|
WO1997015585A1
(en)
|
1995-10-26 |
1997-05-01 |
Kanebo, Ltd. |
Fucose derivatives, drugs containing the same as active ingredient, and intermediates for producing the same
|
|
US5747463A
(en)
|
1995-11-13 |
1998-05-05 |
Bristol-Myers Squibb Company |
Malonate derivatives of glycolipids as cell adhesion inhibitors
|
|
JPH09176047A
(ja)
|
1995-12-25 |
1997-07-08 |
Unitika Ltd |
外用医薬製剤
|
|
DE19602355A1
(de)
|
1996-01-24 |
1997-07-31 |
Hoechst Ag |
Mehrfach fucosylierte Dicarbonsäuren mit antiadhäsiven Eigenschaften
|
|
AU1542397A
(en)
|
1996-01-30 |
1997-08-22 |
Novartis Ag |
Sialyl-lewisa and sialyl-lewisx epitope analogues
|
|
AU1444697A
(en)
|
1996-01-30 |
1997-08-22 |
Novartis Ag |
Sialyl-lewisa and sialyl-lewisx epitope analogues
|
|
EP0902681B1
(en)
|
1996-03-01 |
2002-05-22 |
The Regents of the University of California |
Inhibition of selectin binding
|
|
US5710023A
(en)
|
1996-03-01 |
1998-01-20 |
Genetics Institute, Inc. |
IL-13 cytokine receptor chain
|
|
US6344545B1
(en)
|
1996-06-14 |
2002-02-05 |
Progenics Pharmaceuticals, Inc. |
Method for preventing HIV-1 infection of CD4+ cells
|
|
US5654412A
(en)
|
1996-05-29 |
1997-08-05 |
Glycomed Incorporated |
Processes for the synthesis of sialyl Lewisx compounds
|
|
US5994402A
(en)
|
1996-06-05 |
1999-11-30 |
Rotstein; Ori D. |
Anti-inflammatory and anti-pyretic method
|
|
US5919768A
(en)
|
1996-06-26 |
1999-07-06 |
Texas Biotechnology Corporation |
Di- and trivalent small molecule selectin inhibitors
|
|
NZ334048A
(en)
|
1996-08-08 |
2000-05-26 |
Novartis Ag |
Mimetics of natural carbohydrate epitotes as ligands for E and P Selectin
|
|
US5830871A
(en)
|
1996-10-28 |
1998-11-03 |
The Scripps Research Institute |
Inhibitors of E-, P- and L-selectin binding
|
|
GB9618520D0
(en)
|
1996-09-05 |
1996-10-16 |
Chiroscience Ltd |
Compounds and their therapeutic use
|
|
US6592872B1
(en)
|
1996-09-17 |
2003-07-15 |
The United States Of America As Represented By The Department Of Health And Human Services |
Targeting antigens to the MHC class I processing pathway with an anthrax toxin fusion protein
|
|
DE69737562T2
(de)
|
1996-09-27 |
2007-12-27 |
The Trustees Of Columbia University In The City Of New York |
Behandlung einer ischämischen störung und zur verbesserung des infarktergebnis
|
|
US6110897A
(en)
|
1996-10-10 |
2000-08-29 |
Glycorex Ab |
Antiinflammatory cell adhesion inhibitors
|
|
WO1998021334A2
(en)
|
1996-11-13 |
1998-05-22 |
Morphogenesis, Inc. |
Antibody mg1 recognizing a small subset of human hematopoietic cells
|
|
WO1998037902A1
(en)
|
1997-02-28 |
1998-09-03 |
The Regents Of The University Of California |
Inhibition of cell-cell binding by lipid assemblies
|
|
US6120751A
(en)
|
1997-03-21 |
2000-09-19 |
Imarx Pharmaceutical Corp. |
Charged lipids and uses for the same
|
|
SE9701127D0
(sv)
|
1997-03-26 |
1997-03-26 |
Karolinska Innovations Ab |
Antigenic fusionprotein carrying GALal, 3GAL epitopes
|
|
JP3720520B2
(ja)
|
1997-03-27 |
2005-11-30 |
タカラバイオ株式会社 |
糖と標的物との相互作用の測定方法
|
|
US6413760B1
(en)
|
1997-04-15 |
2002-07-02 |
Genetics Institute, Inc. |
Highly purified mocarhagin cobra venom protease polynucleotides endcoding same and related proteases and therapeutic uses thereof
|
|
US5916910A
(en)
|
1997-06-04 |
1999-06-29 |
Medinox, Inc. |
Conjugates of dithiocarbamates with pharmacologically active agents and uses therefore
|
|
US6193973B1
(en)
|
1997-08-22 |
2001-02-27 |
B. David Tuttle |
Dietary supplement for boosting energy and increasing muscular strength
|
|
US5948628A
(en)
|
1997-09-05 |
1999-09-07 |
The Board Of Regents Of The University Of Oklahoma |
Methods of screening for compounds which mimic galectin-1
|
|
US7018637B2
(en)
|
1998-02-23 |
2006-03-28 |
Aventis Pasteur, Inc |
Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
|
|
WO1999043356A1
(en)
|
1998-02-25 |
1999-09-02 |
Hsc Research Development Limited Partnership |
Antibiotic-ligand conjugates and methods of use thereof
|
|
WO1999043353A2
(en)
|
1998-02-26 |
1999-09-02 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Combination anti-selectin and immunosuppressant therapy
|
|
US6458777B1
(en)
|
1998-03-13 |
2002-10-01 |
Mucosal Therapeutics Llc |
Methods and compositions for treating and preventing mucositis
|
|
CA2245224A1
(en)
|
1998-08-14 |
2000-02-14 |
Jiang-Hong Giong |
Chemokine receptor antagonists and chemotherapeutics
|
|
US6265192B1
(en)
|
1998-03-20 |
2001-07-24 |
The Regents Of The University Of California |
Glycosly sulfortransferase-3
|
|
US6365365B1
(en)
|
1998-03-20 |
2002-04-02 |
The Regents Of The University Of California |
Method of determining whether an agent modulates glycosyl sulfotransferase-3
|
|
US6037333A
(en)
|
1998-05-07 |
2000-03-14 |
Trustees Of Tufts College |
Microbe-inhibiting compositions
|
|
ATE473759T1
(de)
|
1998-05-22 |
2010-07-15 |
Univ Leland Stanford Junior |
Bifunktionelle moleküle sowie darauf basierende therapien.
|
|
MXPA00012586A
(es)
|
1998-06-16 |
2004-05-21 |
Univ Oklahoma |
Glicosulfopeptidos y metodos de sintesis y uso de los mismos.
|
|
US6004815A
(en)
|
1998-08-13 |
1999-12-21 |
The Regents Of The University Of California |
Bacteria expressing nonsecreted cytolysin as intracellular microbial delivery vehicles to eukaryotic cells
|
|
CA2344652C
(en)
|
1998-09-21 |
2007-11-20 |
Otsuka Pharmaceutical Co., Ltd. |
Carboxymethylgalactose derivatives
|
|
US6960566B1
(en)
|
1998-11-06 |
2005-11-01 |
The Wister Institute of Anatomy and Biology |
Compositions and methods for treatment of cancer
|
|
DE69941031D1
(de)
|
1998-11-12 |
2009-08-06 |
Novolytics Inc |
Zusammensetzungen und verfahren zur erzeugung von gefässeokklusion
|
|
GB9904387D0
(en)
|
1999-02-25 |
1999-04-21 |
Pharmacia & Upjohn Spa |
Antitumour synergistic composition
|
|
EP1189609A4
(en)
|
1999-05-03 |
2002-10-30 |
Smithkline Beecham Corp |
CXCR-4 RECEPTOR ANTAGONISTS AND THROMBOPOIETIN MIMETIKA
|
|
US6515117B2
(en)
|
1999-10-12 |
2003-02-04 |
Bristol-Myers Squibb Company |
C-aryl glucoside SGLT2 inhibitors and method
|
|
US6887842B1
(en)
|
1999-11-19 |
2005-05-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Modulating a pharmacokinetic property of a drug by administering a bifunctional molecule containing the drug
|
|
US7204981B2
(en)
|
2000-03-28 |
2007-04-17 |
Eli Lilly And Company |
Methods of treating diseases with activated protein C
|
|
PT1309726E
(pt)
|
2000-03-30 |
2010-03-08 |
Whitehead Biomedical Inst |
Mediadores de interferência por rna específicos de sequência de rna
|
|
US6683056B2
(en)
|
2000-03-30 |
2004-01-27 |
Bristol-Myers Squibb Company |
O-aryl glucoside SGLT2 inhibitors and method
|
|
JP2003534291A
(ja)
|
2000-05-19 |
2003-11-18 |
ザ センター フォー ブラッド リサーチ インク |
Ｐ−セレクチン活性の変調による止血障害の診断及び治療方法
|
|
US20020165178A1
(en)
|
2000-06-28 |
2002-11-07 |
Christian Schetter |
Immunostimulatory nucleic acids for the treatment of anemia, thrombocytopenia, and neutropenia
|
|
WO2002022820A1
(en)
|
2000-09-12 |
2002-03-21 |
Genetics Institute, Llc |
Inhibition of stenosis or restenosis by p-selectin antagonists
|
|
EP1328260A2
(en)
|
2000-10-18 |
2003-07-23 |
Massachusetts Institute Of Technology |
Methods and products related to pulmonary delivery of polysaccharides
|
|
CA2428721A1
(en)
|
2000-11-14 |
2002-05-23 |
The General Hospital Corporation |
Blockade of t cell migration into epithelial gvhd target tissues
|
|
EP1337539A2
(en)
|
2000-11-29 |
2003-08-27 |
Bracco International B.V. |
Linkable sialyl lewis x analogs
|
|
US20020132220A1
(en)
|
2000-12-27 |
2002-09-19 |
Berens Kurt L. |
Use of selectin antagonists in organ preservation solutions
|
|
BR0208474A
(pt)
|
2001-03-28 |
2006-02-21 |
Harvard College |
método para fornecer um antìgeno alvo ao citossol de uma célula, polipeptìdeo isolado, dna isolado, vetor, composição farmacêutica, métodos para gerar uma resposta imune mediana por célula em um mamìfero, para produzir uma proteìna, e para medir uma resposta imune mediada por célula, e, kit para medir respostas imunes mediadas por célula in vitro
|
|
US20030198639A1
(en)
|
2002-04-16 |
2003-10-23 |
Frenette Paul S. |
Methods of treating sickle cell disease
|
|
US7087212B2
(en)
|
2001-08-17 |
2006-08-08 |
Mallinckrodt, Inc |
Multicomponent assemblies having enhanced binding properties for diagnosis and therapy
|
|
AU2002337913A1
(en)
|
2001-10-19 |
2003-04-28 |
Richard D. Cummings |
Glycosulfopeptide inhibitors and methods of use thereof
|
|
US20030211078A1
(en)
|
2001-12-07 |
2003-11-13 |
Heavner George A. |
Pseudo-antibody constructs
|
|
EP1465889B1
(en)
|
2001-12-21 |
2017-03-22 |
Genzyme Corporation |
Chemokine receptor binding heterocyclic compounds with enhanced efficacy
|
|
US20030186942A1
(en)
|
2002-01-16 |
2003-10-02 |
Crooks Peter A. |
Compounds of use in the treatment of epilepsy, seizure, and electroconvulsive disorders
|
|
EP1542704A1
(en)
|
2002-04-18 |
2005-06-22 |
Stephen H. Embury |
Method and composition for preventing pain in sickle cell patients
|
|
JP5183010B2
(ja)
|
2002-05-16 |
2013-04-17 |
グリコミメティクス， インコーポレイテッド |
セレクチンによって媒介される機能を阻害するための化合物および方法
|
|
AU2003245595A1
(en)
|
2002-07-03 |
2004-01-23 |
Glycomimetics, Inc. |
Compositions and methods for diagnosis and therapy of medical conditions involving angiogenesis
|
|
CA2504755C
(en)
|
2002-10-11 |
2010-12-14 |
University Of Maryland Biotechnology Institute |
Carbohydrate-based synthetic vaccines for hiv
|
|
CA2511174A1
(en)
|
2002-12-20 |
2004-07-15 |
Glycomimetics, Inc. |
Oligosaccharides and conjugates thereof for the treatement of pseudomonas bacteria infection
|
|
US6844125B2
(en)
|
2003-03-20 |
2005-01-18 |
Kabushiki Kaisha Toshiba |
Combination of developing agents, image forming apparatus, and method for forming image
|
|
US7332334B2
(en)
|
2003-04-18 |
2008-02-19 |
Oklahoma Medical Research Foundation |
Hematopoietic stem cells treated by in vitro fucosylation and methods of use
|
|
US20040219158A1
(en)
|
2003-05-02 |
2004-11-04 |
Glycomimetics, Inc. |
Compositions and methods for diagnosis and therapy of medical conditions involving infection with pseudomonas bacteria
|
|
WO2005016349A1
(en)
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Methods of inhibiting leukocyte accumulation
|
|
EP1689781A4
(en)
|
2003-11-07 |
2007-06-13 |
Brigham & Womens Hospital |
ANTIBODIES TO CD44 GLYCOFORMS AND ITS APPLICATIONS
|
|
ATE383367T1
(de)
|
2003-11-19 |
2008-01-15 |
Glycomimetics Inc |
Spezifischer antagonist sowohl für e- als auch p- selektine
|
|
JP2007524658A
(ja)
|
2003-11-19 |
2007-08-30 |
グリコミメティクス， インコーポレイテッド |
Ｅ−およびｐ−セレクチンの両方のための糖模倣物アンタゴニスト
|
|
AU2004299267A1
(en)
|
2003-12-18 |
2005-06-30 |
Unibioscreen S.A. |
Glycosylated steroid derivatives with anti-migratory activity
|
|
GB0404434D0
(en)
|
2004-02-27 |
2004-03-31 |
Novartis Ag |
Organic compounds
|
|
US7745421B2
(en)
|
2004-05-25 |
2010-06-29 |
The Johns Hopkins University |
Methods and compositions for treating diseases and disorders associated with Siglec-8 expressing cells
|
|
JP2008504531A
(ja)
|
2004-06-24 |
2008-02-14 |
ザ スクリップス リサーチ インスティテュート |
切断可能なリンカーを有するアレイ
|
|
WO2006017180A2
(en)
|
2004-07-09 |
2006-02-16 |
Progenics Pharmaceuticals, Inc. |
Glycopeptide dimers and uses thereof
|
|
WO2006022454A1
(ja)
|
2004-08-27 |
2006-03-02 |
Ono Pharmaceutical Co., Ltd |
塩基性基を含有する化合物およびその用途
|
|
WO2006062946A2
(en)
|
2004-12-06 |
2006-06-15 |
University Of Florida Research Foundation, Inc. |
Incorporation of bone marrow derived stem cells in tumors
|
|
WO2006074428A2
(en)
|
2005-01-07 |
2006-07-13 |
Emory University |
Cxcr4 antagonists for the treatment of medical disorders
|
|
CA2593612A1
(en)
|
2005-01-07 |
2006-07-13 |
Emory University |
Cxcr4 antagonists for the treatment of hiv infection
|
|
EP1885356A2
(en)
|
2005-02-17 |
2008-02-13 |
Icos Corporation |
Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
|
|
WO2006105019A1
(en)
|
2005-03-25 |
2006-10-05 |
Wisconsin Alumni Research Foundation |
Compounds and methods for treating seizure disorders
|
|
US20090036386A1
(en)
|
2005-05-25 |
2009-02-05 |
Glycomimetics, Inc |
Heterobifunctional compounds for selectin inhibition
|
|
US20060287253A1
(en)
|
2005-06-17 |
2006-12-21 |
Kriegler Steven M |
Compounds and methods for treating seizure disorders
|
|
MX2008000974A
(es)
|
2005-07-22 |
2008-03-27 |
Univ California |
Composiciones de heparina e inhibicion de selectina.
|
|
WO2007021721A2
(en)
|
2005-08-09 |
2007-02-22 |
Glycomimetics, Inc. |
Glycomimetic inhibitors of the pa-il lectin, pa-iil lectin or both the lectins from pseudomonas
|
|
MX2008002190A
(es)
|
2005-08-15 |
2008-04-22 |
Scripps Research Inst |
Metodos para identificar agentes terapeuticos.
|
|
US20080234294A1
(en)
|
2005-08-18 |
2008-09-25 |
Novartis Ag |
Cxcr4 Binding Molecules
|
|
PT1934236E
(pt)
|
2005-09-02 |
2012-12-26 |
Glycomimetics Inc |
Inibidores de pan-selectina heterobifuncionais
|
|
WO2007033329A1
(en)
|
2005-09-14 |
2007-03-22 |
University Of Maryland Biotechnology Institute Off. Of Research Admin./ Tech.Dev. |
Synthetic polyvalent carbohydrates as components of microbicides
|
|
WO2007143052A1
(en)
|
2006-06-01 |
2007-12-13 |
Glycomimetics, Inc. |
Galactosides and thiodigalactosides as inhibitors of pa-il lectin from pseudomonas
|
|
WO2007146188A2
(en)
|
2006-06-07 |
2007-12-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Anti-leukocyte recruitment therapy for the treatment of seizures and epilepsy
|
|
WO2008002449A2
(en)
|
2006-06-23 |
2008-01-03 |
Glycomimetics, Inc. |
Glycomimetic inhibitors of siglec-8
|
|
US8080659B2
(en)
|
2006-07-11 |
2011-12-20 |
Emory University |
CXCR4 antagonists including diazine and triazine structures for the treatment of medical disorders
|
|
US20080227799A1
(en)
|
2006-07-11 |
2008-09-18 |
Liotta Dennis C |
CXCR4 Antagonists Including Heteroatoms for the Treatment of Medical Disorders
|
|
WO2008008852A2
(en)
|
2006-07-11 |
2008-01-17 |
Emory University |
Cxcr4 antagonists including heteroatoms for the treatment of medical disorders
|
|
US7998740B2
(en)
|
2006-07-18 |
2011-08-16 |
Robert Sackstein |
Cytokine induction of selectin ligands on cells
|
|
US7964569B2
(en)
|
2006-10-12 |
2011-06-21 |
Glycomimetics, Inc. |
Glycomimetic replacements for hexoses and N-acetyl hexosamines
|
|
US20080306098A1
(en)
|
2006-11-06 |
2008-12-11 |
Mutz Mitchell W |
Pharmacokinetics of protease inhibitors and other drugs
|
|
WO2008087259A1
(en)
|
2007-01-18 |
2008-07-24 |
Suomen Punainen Risti, Veripalvelu |
Novel carbohydrate profile compositions from human cells and methods for analysis and modification thereof
|
|
EP2457573A1
(en)
|
2007-02-09 |
2012-05-30 |
GlycoMimetics, Inc. |
Methods of use of glycomimetics with replacements for hexoses and N-Acetyl hexosamines
|
|
US20080261978A1
(en)
|
2007-03-08 |
2008-10-23 |
Clark Michael P |
Chemokine receptor modulators
|
|
US20090054334A1
(en)
|
2007-05-23 |
2009-02-26 |
Mutz Mitchell W |
Combinatorial improvement of bifunctional drug properties
|
|
US8039442B2
(en)
|
2007-07-18 |
2011-10-18 |
Glycomimetics, Inc. |
Compounds and methods for treatment of sickle cell disease or complications associated therewith
|
|
US20100303766A1
(en)
|
2007-08-08 |
2010-12-02 |
Kyowa Hakko Kirin Co., Ltd. |
Cell population with enhanced transplantation activity
|
|
AU2008310664A1
(en)
|
2007-10-12 |
2009-04-16 |
Transmolecular, Inc. |
Systemic administration of chlorotoxin agents for the diagnosis and treatment of tumors
|
|
FI20070853A0
(fi)
|
2007-11-09 |
2007-11-09 |
Glykos Finland Oy |
Glykaania sitovat monoklonaaliset vasta-aineet
|
|
US9486497B2
(en)
|
2007-12-10 |
2016-11-08 |
The University Of Queensland |
Treatment of immunocompromised conditions
|
|
US8895510B2
(en)
|
2008-04-08 |
2014-11-25 |
Glycomimetics, Inc. |
Pan-selectin inhibitor with enhanced pharmacokinetic activity
|
|
EP2318015B1
(en)
|
2008-06-13 |
2013-08-07 |
GlycoMimetics, Inc. |
Treatment of cancers of the blood using selected glycomimetic compounds
|
|
WO2010025416A1
(en)
|
2008-08-29 |
2010-03-04 |
Genzyme Corporation |
Cxcr4 antagonists for kidney injury
|
|
US20100240773A1
(en)
|
2009-03-23 |
2010-09-23 |
Kenneth Korzekwa |
Multifunctional linkers
|
|
FI20095459A0
(fi)
|
2009-04-24 |
2009-04-24 |
Suomen Punainen Risti Veripalv |
Uusia määritysmenetelmiä
|
|
CN102421441B
(zh)
|
2009-05-01 |
2015-04-01 |
糖模拟物有限公司 |
E-选择蛋白和cxcr4趋化因子受体的异双功能抑制剂
|
|
WO2010132315A1
(en)
|
2009-05-13 |
2010-11-18 |
Endgenitor Technologies, Inc. |
Enhanced hematopoietic stem cell engraftment
|
|
US20110251148A1
(en)
|
2010-04-07 |
2011-10-13 |
Glycomimetics, Inc. |
Glycomimetic compounds and methods to inhibit infection by hiv
|
|
US8921328B2
(en)
|
2010-09-14 |
2014-12-30 |
Glycomimetics, Inc. |
E-selectin antagonists
|
|
WO2012047918A1
(en)
|
2010-10-04 |
2012-04-12 |
Glycomimetics, Inc. |
Anti-epileptogenic agents
|
|
FI20106031A0
(fi)
|
2010-10-06 |
2010-10-06 |
Suomen Punainen Risti Veripalv |
Menetelmä solujen eristämiseksi ja menetelmällä eristetty solupopulaatio
|
|
WO2012061662A1
(en)
|
2010-11-03 |
2012-05-10 |
Glycomimetics, Inc. |
Glycomimetic-peptidomimetic inhibitors of e-selectins and cxcr4 chemokine receptors
|
|
US8765126B2
(en)
|
2011-05-05 |
2014-07-01 |
Robert Sackstein |
Methods of treating complications and disorders associated with G-CSF administration
|
|
WO2013090926A1
(en)
|
2011-12-16 |
2013-06-20 |
Rembach Paul F |
System and method for cooling and maintaining building containing heat generating electronics
|
|
CN104039805B
(zh)
|
2011-12-22 |
2016-11-16 |
糖模拟物有限公司 |
E-选择蛋白拮抗剂化合物、组合物及使用方法
|
|
EP2914610A2
(en)
*
|
2012-10-31 |
2015-09-09 |
GlycoMimetics, Inc. |
Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists
|
|
HUE038423T2
(hu)
|
2012-12-07 |
2018-10-29 |
Glycomimetics Inc |
E-szelektin antagonistákat felhasználó vegyületek, készítmények és eljárások vérképzõ sejtek mobilizációjára
|
|
WO2014149837A1
(en)
|
2013-03-15 |
2014-09-25 |
Glycomimetics, Inc. |
Compounds and methods to enhance the oral availability of glycomimetics
|
|
CA2920377A1
(en)
|
2013-08-05 |
2015-02-12 |
Cambridge Enterprise Limited |
Inhibition of cxcr4 signaling in cancer immunotherapy
|
|
WO2015048616A1
(en)
|
2013-09-30 |
2015-04-02 |
Glycomimetics, Inc. |
Methods and compositions for treating and/or preventing mucositis
|
|
US20160333043A1
(en)
|
2014-01-17 |
2016-11-17 |
Glycomimetics, Inc. |
E-Selectin Antagonists Modified By Macrocycle Formation to the Galactose
|
|
EP3569609A1
(en)
|
2014-12-03 |
2019-11-20 |
GlycoMimetics, Inc. |
Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors
|
|
WO2016164394A1
(en)
|
2015-04-08 |
2016-10-13 |
Glycomimetics, Inc. |
2-halo-galactose-containing selectin antagonists
|
|
WO2017023918A1
(en)
|
2015-08-03 |
2017-02-09 |
Glycomimetics, Inc. |
Methods for the mobilization and use of t-cells with enhanced reconstitution potential and life-span
|
|
EP3383882A1
(en)
|
2015-12-02 |
2018-10-10 |
GlycoMimetics, Inc. |
Heterobifunctional pan-selectin antagonists having a triazole linker
|
|
WO2017151708A1
(en)
|
2016-03-02 |
2017-09-08 |
Glycomimetics, Inc. |
Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin
|
|
CA3037850A1
(en)
*
|
2016-10-07 |
2018-04-12 |
Glycomimetics, Inc. |
Highly potent multimeric e-selectin antagonists
|
|
EP4003364A1
(en)
*
|
2019-07-31 |
2022-06-01 |
GlycoMimetics, Inc. |
Use of highly potent multimeric e-selectin antagonists for treating sickle cell disease
|