JP2019529402A5 - - Google Patents
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- JP2019529402A5 JP2019529402A5 JP2019513787A JP2019513787A JP2019529402A5 JP 2019529402 A5 JP2019529402 A5 JP 2019529402A5 JP 2019513787 A JP2019513787 A JP 2019513787A JP 2019513787 A JP2019513787 A JP 2019513787A JP 2019529402 A5 JP2019529402 A5 JP 2019529402A5
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- Japan
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- 0 *C(CC(CCC(*)(*)*)C1*)O[C@@]1O[C@@](C(*)C1*)C(*)O[C@]1OC(*)(*)* Chemical compound *C(CC(CCC(*)(*)*)C1*)O[C@@]1O[C@@](C(*)C1*)C(*)O[C@]1OC(*)(*)* 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201670733 | 2016-09-20 | ||
| DKPA201670733 | 2016-09-20 | ||
| PCT/EP2017/073747 WO2018054959A1 (en) | 2016-09-20 | 2017-09-20 | Compounds for treatment of lipoprotein metabolism disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019529402A JP2019529402A (ja) | 2019-10-17 |
| JP2019529402A5 true JP2019529402A5 (https=) | 2020-11-05 |
| JP7046381B2 JP7046381B2 (ja) | 2022-04-04 |
Family
ID=59974406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019513787A Expired - Fee Related JP7046381B2 (ja) | 2016-09-20 | 2017-09-20 | リポタンパク質代謝障害の治療のための化合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11173177B2 (https=) |
| EP (1) | EP3515455B1 (https=) |
| JP (1) | JP7046381B2 (https=) |
| CN (1) | CN110494145A (https=) |
| AU (1) | AU2017329799A1 (https=) |
| CA (1) | CA3035875A1 (https=) |
| DK (1) | DK3515455T3 (https=) |
| ES (1) | ES2871783T3 (https=) |
| WO (1) | WO2018054959A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3973958A3 (en) * | 2015-03-20 | 2022-06-22 | Aarhus Universitet | Inhibitors of pcsk9 for treatment of lipoprotein metabolism disorders |
| KR102137147B1 (ko) * | 2018-07-16 | 2020-07-24 | 경희대학교 산학협력단 | 벤질 알파-d-갈락토피라노사이드 또는 (-)-세코이소라리시레시놀-9'-o-베타-d-글루코피라노사이드를 포함하는 당뇨병 예방 또는 치료용 조성물 |
| SE543275C2 (en) * | 2019-03-07 | 2020-11-10 | Tx Medic Ab | Treatment efficiency evaluation |
| WO2021122793A1 (en) * | 2019-12-17 | 2021-06-24 | Norinvent Ab | Sulfated disaccharides as enhancers of transmucosal drug uptake |
| US12378557B2 (en) | 2020-08-25 | 2025-08-05 | Regeneron Pharmaceuticals, Inc. | Treatment of sepsis with PCSK9 and LDLR modulators |
| CN116854752A (zh) * | 2022-03-28 | 2023-10-10 | 南开大学 | 肝素三糖结构化合物及其制药应用 |
| CN116270507A (zh) * | 2023-03-02 | 2023-06-23 | 青岛海洋生物医药研究院股份有限公司 | 一种含脂蛋白脂酶刺激剂的舌下含片及其制备方法和应用 |
| CN119708089A (zh) * | 2023-09-27 | 2025-03-28 | 南开大学 | 一种磺酸化三糖及其制备方法和治疗应用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4602003A (en) * | 1982-05-17 | 1986-07-22 | Medical Research Foundation Of Oregon | Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia |
| ES2114948T3 (es) * | 1991-10-04 | 1998-06-16 | Procter & Gamble | Compuestos disminuidores del colesterol y procedimiento para prepararlos. |
| DE69232137T2 (de) | 1991-11-25 | 2002-05-29 | Enzon Inc | Multivalente antigen-bindende proteine |
| US5366473A (en) | 1992-08-18 | 1994-11-22 | Ultrasonic Sensing And Monitoring Systems, Inc. | Method and apparatus for applying vascular grafts |
| GB9221657D0 (en) | 1992-10-15 | 1992-11-25 | Scotgen Ltd | Recombinant bispecific antibodies |
| WO1994013806A1 (en) | 1992-12-11 | 1994-06-23 | The Dow Chemical Company | Multivalent single chain antibodies |
| CN1487996B (zh) | 2000-11-30 | 2010-06-16 | 米德列斯公司 | 用于生产人类抗体的转基因转染色体啮齿动物 |
| US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| US20030133939A1 (en) | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
| US8828952B2 (en) | 2007-10-16 | 2014-09-09 | Progen Pharmaceuticals Limited | Sulfated oligosaccharide derivatives |
| TWI516501B (zh) | 2008-09-12 | 2016-01-11 | 禮納特神經系統科學公司 | Ｐｃｓｋ９拮抗劑類 |
| CN102656153B (zh) | 2009-10-29 | 2015-02-18 | 延世大学校产学协力团 | 新型血管渗漏阻断剂 |
| WO2013091103A1 (en) | 2011-12-20 | 2013-06-27 | Adaerata, Limited Partnership | Single domain antibodies as inhibitors of pcsk9 |
| WO2013148284A1 (en) | 2012-03-29 | 2013-10-03 | Genentech, Inc. | Antibodies that bind to a pcsk9 cleavage site and methods of use |
| US9255154B2 (en) | 2012-05-08 | 2016-02-09 | Alderbio Holdings, Llc | Anti-PCSK9 antibodies and use thereof |
| CA2874244A1 (en) | 2012-05-25 | 2013-11-28 | Catabasis Pharmaceuticals, Inc. | Methods of lowering proprotein convertase subtilisin/kexin type 9 (pcsk9) |
| US20150190369A1 (en) | 2012-07-03 | 2015-07-09 | Majambu Mbikay | Quercetin-3-glucoside and uses thereof |
| HK1210953A1 (en) | 2012-08-02 | 2016-05-13 | Stealth Peptides International, Inc. | Methods for treatment of atherosclerosis |
| JP2016514668A (ja) | 2013-03-15 | 2016-05-23 | アムジエン・インコーポレーテツド | プロタンパク質コンベルターゼスブチリシンケクシン９型に結合するヒト抗原結合タンパク質 |
| EP3197492A1 (en) | 2014-09-23 | 2017-08-02 | Pfizer Inc | Treatment with anti-pcsk9 antibodies |
| EP3973958A3 (en) | 2015-03-20 | 2022-06-22 | Aarhus Universitet | Inhibitors of pcsk9 for treatment of lipoprotein metabolism disorders |
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2017
- 2017-09-20 CA CA3035875A patent/CA3035875A1/en not_active Abandoned
- 2017-09-20 US US16/334,131 patent/US11173177B2/en not_active Expired - Fee Related
- 2017-09-20 EP EP17776978.3A patent/EP3515455B1/en active Active
- 2017-09-20 AU AU2017329799A patent/AU2017329799A1/en not_active Abandoned
- 2017-09-20 DK DK17776978.3T patent/DK3515455T3/da active
- 2017-09-20 CN CN201780069925.3A patent/CN110494145A/zh active Pending
- 2017-09-20 JP JP2019513787A patent/JP7046381B2/ja not_active Expired - Fee Related
- 2017-09-20 WO PCT/EP2017/073747 patent/WO2018054959A1/en not_active Ceased
- 2017-09-20 ES ES17776978T patent/ES2871783T3/es active Active
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2021
- 2021-08-16 US US17/403,102 patent/US20220054530A1/en not_active Abandoned