JP2019528760A5 - - Google Patents

Download PDF

Info

Publication number
JP2019528760A5
JP2019528760A5 JP2019517047A JP2019517047A JP2019528760A5 JP 2019528760 A5 JP2019528760 A5 JP 2019528760A5 JP 2019517047 A JP2019517047 A JP 2019517047A JP 2019517047 A JP2019517047 A JP 2019517047A JP 2019528760 A5 JP2019528760 A5 JP 2019528760A5
Authority
JP
Japan
Prior art keywords
composition
cells
modified
population
unnatural
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019517047A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019528760A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/054799 external-priority patent/WO2018064681A1/en
Publication of JP2019528760A publication Critical patent/JP2019528760A/ja
Priority to JP2020168576A priority Critical patent/JP7610948B2/ja
Publication of JP2019528760A5 publication Critical patent/JP2019528760A5/ja
Priority to JP2021156988A priority patent/JP2021191312A/ja
Priority to JP2024076779A priority patent/JP7817312B2/ja
Priority to JP2026017764A priority patent/JP2026108616A/ja
Pending legal-status Critical Current

Links

JP2019517047A 2016-09-30 2017-10-02 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法 Pending JP2019528760A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2020168576A JP7610948B2 (ja) 2016-09-30 2020-10-05 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法
JP2021156988A JP2021191312A (ja) 2016-09-30 2021-09-27 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法
JP2024076779A JP7817312B2 (ja) 2016-09-30 2024-05-09 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法
JP2026017764A JP2026108616A (ja) 2016-09-30 2026-02-05 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201662402707P 2016-09-30 2016-09-30
US62/402,707 2016-09-30
US201762502508P 2017-05-05 2017-05-05
US62/502,508 2017-05-05
US201762553058P 2017-08-31 2017-08-31
US62/553,058 2017-08-31
US201762556309P 2017-09-08 2017-09-08
US62/556,309 2017-09-08
PCT/US2017/054799 WO2018064681A1 (en) 2016-09-30 2017-10-02 Modified stem cell memory t cells, methods of making and methods of using same

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2020168576A Division JP7610948B2 (ja) 2016-09-30 2020-10-05 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法
JP2021156988A Division JP2021191312A (ja) 2016-09-30 2021-09-27 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法

Publications (2)

Publication Number Publication Date
JP2019528760A JP2019528760A (ja) 2019-10-17
JP2019528760A5 true JP2019528760A5 (cg-RX-API-DMAC10.html) 2020-11-12

Family

ID=60245180

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2019517047A Pending JP2019528760A (ja) 2016-09-30 2017-10-02 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法
JP2020168576A Active JP7610948B2 (ja) 2016-09-30 2020-10-05 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法
JP2021156988A Pending JP2021191312A (ja) 2016-09-30 2021-09-27 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法
JP2024076779A Active JP7817312B2 (ja) 2016-09-30 2024-05-09 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法
JP2026017764A Pending JP2026108616A (ja) 2016-09-30 2026-02-05 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2020168576A Active JP7610948B2 (ja) 2016-09-30 2020-10-05 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法
JP2021156988A Pending JP2021191312A (ja) 2016-09-30 2021-09-27 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法
JP2024076779A Active JP7817312B2 (ja) 2016-09-30 2024-05-09 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法
JP2026017764A Pending JP2026108616A (ja) 2016-09-30 2026-02-05 改変された幹細胞メモリーt細胞、その作製方法およびその使用方法

Country Status (9)

Country Link
EP (1) EP3519561A1 (cg-RX-API-DMAC10.html)
JP (5) JP2019528760A (cg-RX-API-DMAC10.html)
KR (4) KR20250011252A (cg-RX-API-DMAC10.html)
CN (1) CN110199015A (cg-RX-API-DMAC10.html)
AU (4) AU2017337147A1 (cg-RX-API-DMAC10.html)
CA (3) CA3105873A1 (cg-RX-API-DMAC10.html)
IL (3) IL287286B (cg-RX-API-DMAC10.html)
SG (2) SG11201901959YA (cg-RX-API-DMAC10.html)
WO (1) WO2018064681A1 (cg-RX-API-DMAC10.html)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110199015A (zh) * 2016-09-30 2019-09-03 波赛达治疗公司 修饰干细胞记忆t细胞、其制造方法与使用方法
US20190119636A1 (en) 2017-10-23 2019-04-25 Poseida Therapeutics, Inc. Modified stem cell memory t cells, methods of making and methods of using same
CA3047313A1 (en) 2016-12-16 2018-06-21 B-Mogen Biotechnologies, Inc. Enhanced hat family transposon-mediated gene transfer and associated compositions, systems, and methods
US11278570B2 (en) 2016-12-16 2022-03-22 B-Mogen Biotechnologies, Inc. Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods
EP3351263A1 (en) 2017-01-20 2018-07-25 Universitätsklinikum Hamburg-Eppendorf Pharmaceutical preparation for treating or preventing tissue adhesion
UA129696C2 (uk) 2017-08-18 2025-07-09 Ньютроліс Інк. СКОНСТРУЙОВАНІ ФЕРМЕНТИ ДНКази ТА ЇХНЄ ЗАСТОСУВАННЯ В ТЕРАПІЇ
US20210015866A1 (en) * 2018-03-23 2021-01-21 La Jolla Institute For Allergy And Immunology Tissue resident memory cell profiles, and uses thereof
WO2019246486A2 (en) 2018-06-21 2019-12-26 B-Mogen Biotechnologies, Inc. ENHANCED hAT FAMILY TRANSPOSON-MEDIATED GENE TRANSFER AND ASSOCIATED COMPOSITIONS, SYSTEMS, AND METHODS
US11058724B2 (en) * 2018-10-08 2021-07-13 Neutrolis, Inc. Methods of using DNASE1-like 3 in therapy
CN112996911A (zh) 2018-10-08 2021-06-18 纽特雷斯股份有限公司 用于制造和疗法的脱氧核糖核酸酶的工程改造
US11352613B2 (en) 2019-02-04 2022-06-07 Neutrolis, Inc. Engineered human extracellular DNASE enzymes
SG11202108357PA (en) 2019-02-15 2021-08-30 Crispr Therapeutics Ag Gene editing for hemophilia a with improved factor viii expression
EP3959305A1 (en) * 2019-04-26 2022-03-02 Allogene Therapeutics, Inc. Methods of manufacturing allogeneic car t cells
BR112021015776A2 (pt) * 2019-06-05 2021-11-09 Bayer Healthcare Llc Edição de gene para hemofilia a com expressão de fator viii melhorada
CN110358734B (zh) 2019-06-13 2020-08-25 首都医科大学宣武医院 以Tcm为主要效应成分的CAR-T制备方法及其应用
MX2022007107A (es) * 2019-12-11 2022-11-14 Myeloid Therapeutics Inc Composiciones celulares terapeuticas y metodos de preparacion y usos de las mismas.
EP4110356A4 (en) * 2020-02-28 2024-03-27 Wisconsin Alumni Research Foundation NON-VIRAL GENERATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS OBTAINED BY GENE EDITING
AU2021236391A1 (en) 2020-03-13 2022-09-29 Capricor, Inc. Exosomal nucleic acid vaccine modularly configured to harness multiple antigen presentation mechanisms
WO2021222479A1 (en) 2020-04-28 2021-11-04 Lyell Immunopharma, Inc. Methods for culturing cells
EP4298205A1 (en) * 2021-02-23 2024-01-03 Poseida Therapeutics, Inc. Genetically modified induced pluripotent stem cells and methods of use thereof
CN114990061B (zh) * 2022-06-30 2023-08-29 河南省人民医院 一种诱导扩增中央记忆性t细胞的培养方法
CN116444666A (zh) * 2023-05-22 2023-07-18 上海交通大学医学院附属仁济医院 Cdh17特异性诊疗一体化分子影像探针的制备方法及应用
WO2025221789A1 (en) 2024-04-16 2025-10-23 Poseida Therapeutics, Inc. Compositions and methods for use in car/tcr cell therapies
CN118272305B (zh) * 2024-04-29 2025-04-08 深圳泽医细胞治疗集团有限公司 一种免疫细胞的培养基及其应用
CN118813532A (zh) * 2024-07-30 2024-10-22 中国医学科学院基础医学研究所 体外制备与扩增tscm细胞的方法
CN118813707A (zh) * 2024-07-30 2024-10-22 中国医学科学院基础医学研究所 体外制备与扩增干性car-t细胞的方法
WO2026080393A1 (en) 2024-10-07 2026-04-16 Poseida Therapeutics, Inc. Compositions and methods for use in car cell therapies
WO2026107088A1 (en) 2024-11-13 2026-05-21 Poseida Therapeutics, Inc. Dual car constructs and methods of use
WO2026107078A1 (en) 2024-11-13 2026-05-21 Poseida Therapeutics, Inc. Chimeric antigen receptor compositions and methods of use

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554101A (en) 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
US5266491A (en) 1989-03-14 1993-11-30 Mochida Pharmaceutical Co., Ltd. DNA fragment and expression plasmid containing the DNA fragment
US5580734A (en) 1990-07-13 1996-12-03 Transkaryotic Therapies, Inc. Method of producing a physical map contigous DNA sequences
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
US5968502A (en) 1991-11-05 1999-10-19 Transkaryotic Therapies, Inc. Protein production and protein delivery
AU7082694A (en) * 1994-05-10 1995-11-29 Kitasato Institute, The Hematopoietic stem cell proliferation accelerator
US6218185B1 (en) 1996-04-19 2001-04-17 The United States Of America As Represented By The Secretary Of Agriculture Piggybac transposon-based genetic transformation system for insects
US6835394B1 (en) 1999-12-14 2004-12-28 The Trustees Of The University Of Pennsylvania Polymersomes and related encapsulating membranes
US7105343B1 (en) 2000-10-31 2006-09-12 University Of Notre Dame Du Lac Methods and compositions for transposition using minimal segments of the eukaryotic transformation vector Piggybac
US6962810B2 (en) 2000-10-31 2005-11-08 University Of Notre Dame Du Lac Methods and compositions for transposition using minimal segments of the eukaryotic transformation vector piggyBac
IL152904A0 (en) * 2002-01-24 2003-06-24 Gamida Cell Ltd Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
CA2495824A1 (en) * 2002-08-19 2004-02-26 Gamida-Cell Ltd. Ex-vivo expansion of hematopoietic stem cell populations in mononuclear cell cultures
EP4733396A2 (en) 2009-02-26 2026-04-29 Poseida Therapeutics, Inc. Hyperactive piggybac transposases
CN107070622B (zh) * 2009-06-02 2021-02-09 太阳专利信托公司 终端装置、通信装置、通信方法和集成电路
US8808748B2 (en) 2010-04-20 2014-08-19 Vindico NanoBio Technology Inc. Biodegradable nanoparticles as novel hemoglobin-based oxygen carriers and methods of using the same
WO2012094679A2 (en) 2011-01-07 2012-07-12 Vindico NanoBio Technology Inc. Compositions and methods for delivery of high-affinity oxygen binding agents to tumors
PT3434775T (pt) 2011-06-07 2020-04-08 Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Gesundheit & Umwelt Gmbh Proteína que tem atividade de nuclease, proteínas de fusão e utilizações das mesmas
EP2814846B1 (en) * 2012-02-13 2020-01-08 Seattle Children's Hospital d/b/a Seattle Children's Research Institute Bispecific chimeric antigen receptors and therapeutic uses thereof
CN105408483A (zh) 2013-03-15 2016-03-16 通用医疗公司 遗传和表观遗传调节蛋白至特定基因组基因座的rna引导的靶向
AU2014235968B2 (en) * 2013-03-21 2018-05-24 Ospedale San Raffaele Srl Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
EP2997134B1 (en) * 2013-05-14 2020-06-24 Board of Regents, The University of Texas System Human application of engineered chimeric antigen receptor (car) t-cells
CN122399016A (zh) * 2014-03-15 2026-07-17 诺华股份有限公司 使用嵌合抗原受体治疗癌症
HUE052552T2 (hu) * 2014-04-09 2021-05-28 Dna Twopointo Inc Javított nukleinsav-konstrukciók eukarióta génexpresszióhoz
US10738278B2 (en) * 2014-07-15 2020-08-11 Juno Therapeutics, Inc. Engineered cells for adoptive cell therapy
AU2015301014B2 (en) 2014-08-08 2021-05-06 Poseida Therapeutics, Inc. Compositions and methods for inducing nanoparticle-mediated microvascular embolization of tumors
BR112017004270B1 (pt) * 2014-09-04 2023-03-07 Stemcell Technologies Inc Método de ativação de células t ou células nk
EP3018200A1 (en) * 2014-11-07 2016-05-11 Fondazione Matilde Tettamanti e Menotti de Machi Onlus Improved method for the generation of genetically modified cells
AU2015358413A1 (en) 2014-12-05 2017-06-29 Poseida Therapeutics, Inc. Compositions and methods for inducing nanoparticle-mediated microvascular embolization of tumors
RU2751362C2 (ru) * 2014-12-29 2021-07-13 Новартис Аг Способы получения экспрессирующих химерный антигенный рецептор клеток
JP2018521689A (ja) * 2015-06-17 2018-08-09 ポセイダ セラピューティクス, インコーポレイテッド タンパク質をゲノム内の特定の遺伝子座に導くための組成物および方法
US10456452B2 (en) 2015-07-02 2019-10-29 Poseida Therapeutics, Inc. Compositions and methods for improved encapsulation of functional proteins in polymeric vesicles
US20170000743A1 (en) 2015-07-02 2017-01-05 Vindico NanoBio Technology Inc. Compositions and Methods for Delivery of Gene Editing Tools Using Polymeric Vesicles
CN110199015A (zh) * 2016-09-30 2019-09-03 波赛达治疗公司 修饰干细胞记忆t细胞、其制造方法与使用方法

Similar Documents

Publication Publication Date Title
EP4427809A3 (en) Altering gene expression in car-t cells and uses thereof
JP2013176400A5 (cg-RX-API-DMAC10.html)
IL287286B (en) Differentiated stem cell memory t cells, methods for their preparation and methods for using them
MX395574B (es) Metodo y composiciones para inmunoterapia celular.
JP2013501505A5 (cg-RX-API-DMAC10.html)
MX2018014941A (es) Anticuerpo para unirse al receptor de interleucina 4.
EA201891212A1 (ru) Адресная дезорганизация клеточного рецептора гкгс
JP2017512484A5 (cg-RX-API-DMAC10.html)
EA201890772A1 (ru) Способ высокоуровневого и стабильного переноса генов в лимфоцитах
HK1216894A1 (zh) 多價結合蛋白組合物
NZ705675A (en) Engineered transgene integration platform (etip) for gene targeting and trait stacking
JP2016500260A5 (cg-RX-API-DMAC10.html)
EP4218409A3 (en) Mice expressing a limited immunoglobulin light chain repertoire
CY1123348T1 (el) Μεθοδος για την παρασκευη ενισχυμενων πολυδυναμων βλαστοκυτταρων απο μεσεγχυματικα βλαστοκυτταρα με τη χρηση κλασματος φλοροταννινης
JP2019534684A5 (cg-RX-API-DMAC10.html)
EP3587560A4 (en) Endodermal cell mass, and method for producing any one of three primary germ layer cell mass from pluripotent cells
Sikorskaya Noosferic aspects of networked collaborations among vocational educational institutions in Russia
PL415351A1 (pl) Sposób namnażania in vitro komórek T regulatorowych (Treg)
JP2013503602A5 (cg-RX-API-DMAC10.html)
JP2014533495A5 (cg-RX-API-DMAC10.html)
Kornienko PRINCIPLES OF FORMING OF SYSTEM OF ECONOMIC ANALYSIS ARE IN MANAGEMENT ENTERPRISE
Phuc et al. Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells
Metelitsa AN ANALYSIS OF DIFFICULTIES READING ACADEMIC ARTCILES OF STUDENTS OF TECHNICAL SPECIALISATIONS AND ATTEMPTS TO SOLVE THEM
Konishchev et al. EARTH'S CRYOSPHERE
Pavlova et al. PREPARATORY PROCESS FOR PUPILS TO THE OLYMPIADS IN INFORMATICS