JP2019528753A5 - - Google Patents

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Publication number
JP2019528753A5
JP2019528753A5 JP2019516383A JP2019516383A JP2019528753A5 JP 2019528753 A5 JP2019528753 A5 JP 2019528753A5 JP 2019516383 A JP2019516383 A JP 2019516383A JP 2019516383 A JP2019516383 A JP 2019516383A JP 2019528753 A5 JP2019528753 A5 JP 2019528753A5
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JP
Japan
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item
items
vaccinia virus
oncolytic vaccinia
nucleic acid
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Pending
Application number
JP2019516383A
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English (en)
Japanese (ja)
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JP2019528753A (ja
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Priority claimed from PCT/US2017/052746 external-priority patent/WO2018057755A1/en
Publication of JP2019528753A publication Critical patent/JP2019528753A/ja
Publication of JP2019528753A5 publication Critical patent/JP2019528753A5/ja
Pending legal-status Critical Current

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JP2019516383A 2016-09-21 2017-09-21 高移動度グループboxi突然変異体 Pending JP2019528753A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662397523P 2016-09-21 2016-09-21
US62/397,523 2016-09-21
PCT/US2017/052746 WO2018057755A1 (en) 2016-09-21 2017-09-21 High mobility group box i mutant

Publications (2)

Publication Number Publication Date
JP2019528753A JP2019528753A (ja) 2019-10-17
JP2019528753A5 true JP2019528753A5 (https=) 2020-11-12

Family

ID=61691108

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019516383A Pending JP2019528753A (ja) 2016-09-21 2017-09-21 高移動度グループboxi突然変異体

Country Status (7)

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US (2) US11065286B2 (https=)
EP (1) EP3515419A4 (https=)
JP (1) JP2019528753A (https=)
KR (1) KR20190059297A (https=)
CN (1) CN110022867A (https=)
AU (2) AU2017332367B2 (https=)
WO (1) WO2018057755A1 (https=)

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CN115300622A (zh) 2015-02-25 2022-11-08 纪念斯隆-凯特琳癌症中心 使用灭活的修饰的痘苗病毒安卡拉作为实体肿瘤的单一免疫疗法或与免疫检查点阻断剂组合
CN107847534B (zh) 2015-04-17 2022-10-04 纪念斯隆凯特琳癌症中心 Mva或mvaδe3l作为抗实体瘤的免疫治疗剂的应用
IL261321B2 (en) 2016-02-25 2023-12-01 Memorial Sloan Kettering Cancer Center Recombinant mva or mvadele3l expressing human flt3l and use thereof as immuno-therapeutic agents against solid tumors
KR20180133395A (ko) 2016-02-25 2018-12-14 메모리얼 슬로안 케터링 캔서 센터 암 면역요법을 위한, 인간 flt3l 또는 gm-csf의 발현이 있거나 없으며 티미딘 키나제가 결실된 복제 가능 약독화 백시니아 바이러스
JP2019535311A (ja) 2016-11-02 2019-12-12 デイビッド エバンス, 合成キメラポックスウイルス
WO2018209315A1 (en) 2017-05-12 2018-11-15 Memorial Sloan Kettering Cancer Center Vaccinia virus mutants useful for cancer immunotherapy
EP3703723A4 (en) 2017-10-31 2021-12-15 KaliVir Immunotherapeutics, Inc. ONCOLYTIC PLATFORM VECTOR FOR SYSTEMS ADMINISTRATION
CN109913422A (zh) * 2017-12-13 2019-06-21 苏州康聚生物科技有限公司 一种包含肿瘤抗原识别受体的免疫细胞及其应用
BR112020014727A2 (pt) * 2018-01-19 2020-12-08 Kolon Life Science, Inc. Vírus vaccinia recombinante e composição farmacêutica compreendendo o mesmo
EP3788142A4 (en) * 2018-05-02 2022-04-27 Tonix Pharma Holdings Limited SYNTHETIC CHIMERIC VACCINE VIRUS
MX2021003013A (es) 2018-09-15 2021-08-11 Memorial Sloan Kettering Cancer Center Poxvirus recombinantes para inmunoterapia contra cáncer.
CA3152973A1 (en) * 2019-08-29 2021-03-04 Bionoxx Inc. Pharmaceutical composition for treating cancer, comprising vaccinia virus and granulopoiesis inhibitor as active ingredients
TW202227621A (zh) 2020-11-19 2022-07-16 美商凱立凡爾免疫治療股份有限公司 重塑腫瘤微環境的溶瘤免疫療法
BR112023022681A2 (pt) 2021-04-30 2024-01-23 Kalivir Immunotherapeutics Inc Vírus oncolíticos para expressão modificada de mhc
IL320318A (en) * 2022-10-19 2025-06-01 Kalivir Immunotherapeutics Inc Nucleic acids encoding tgf-beta inhibitor and il-12 and uses thereof
WO2025184411A1 (en) 2024-02-27 2025-09-04 Calidi Biotherapeutics (Nevada), Inc. Serum-resistant eev viruses and uses thereof

Family Cites Families (10)

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KR20120002613A (ko) 2002-08-12 2012-01-06 제네렉스, 인코포레이티드 폭스바이러스 및 암과 관련된 방법 및 조성물
GB0226251D0 (en) * 2002-11-11 2002-12-18 San Raffaele Centro Fond Acetylated protein
AU2004272607B2 (en) * 2003-09-11 2008-11-06 Cornerstone Therapeutics Inc. Monoclonal antibodies against HMGB1
WO2009054996A2 (en) * 2007-10-25 2009-04-30 Genelux Corporation Systems and methods for viral therapy
US8313896B2 (en) * 2008-04-04 2012-11-20 The General Hospital Corporation Oncolytic herpes simplex virus immunotherapy in the treatment of brain cancer
JP5686814B2 (ja) * 2010-09-17 2015-03-18 独立行政法人科学技術振興機構 Hmgbタンパクによって仲介される免疫応答の活性化の抑制剤及びスクリーニング方法
ES2733211T3 (es) 2011-04-15 2019-11-28 Genelux Corp Cepas clonales de virus vaccinia atenuados y métodos de uso de las mismas
PT3358011T (pt) * 2011-04-26 2020-04-23 Univ Osaka Péptido para induzir a regeneração de um tecido e a sua utilização
FI20115914L (fi) * 2011-09-16 2013-03-17 Oncos Therapeutics Ltd Muunnettu onkolyyttinen virus
RS65104B1 (sr) * 2013-08-22 2024-02-29 Univ Pittsburgh Commonwealth Sys Higher Education Onkolitičke imunoterapije

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