JP2019528753A5 - - Google Patents

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Publication number
JP2019528753A5
JP2019528753A5 JP2019516383A JP2019516383A JP2019528753A5 JP 2019528753 A5 JP2019528753 A5 JP 2019528753A5 JP 2019516383 A JP2019516383 A JP 2019516383A JP 2019516383 A JP2019516383 A JP 2019516383A JP 2019528753 A5 JP2019528753 A5 JP 2019528753A5
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JP
Japan
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item
items
vaccinia virus
oncolytic vaccinia
nucleic acid
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Pending
Application number
JP2019516383A
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English (en)
Japanese (ja)
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JP2019528753A (ja
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Priority claimed from PCT/US2017/052746 external-priority patent/WO2018057755A1/en
Publication of JP2019528753A publication Critical patent/JP2019528753A/ja
Publication of JP2019528753A5 publication Critical patent/JP2019528753A5/ja
Pending legal-status Critical Current

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JP2019516383A 2016-09-21 2017-09-21 高移動度グループboxi突然変異体 Pending JP2019528753A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662397523P 2016-09-21 2016-09-21
US62/397,523 2016-09-21
PCT/US2017/052746 WO2018057755A1 (en) 2016-09-21 2017-09-21 High mobility group box i mutant

Publications (2)

Publication Number Publication Date
JP2019528753A JP2019528753A (ja) 2019-10-17
JP2019528753A5 true JP2019528753A5 (https=) 2020-11-12

Family

ID=61691108

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019516383A Pending JP2019528753A (ja) 2016-09-21 2017-09-21 高移動度グループboxi突然変異体

Country Status (7)

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US (2) US11065286B2 (https=)
EP (1) EP3515419A4 (https=)
JP (1) JP2019528753A (https=)
KR (1) KR20190059297A (https=)
CN (1) CN110022867A (https=)
AU (2) AU2017332367B2 (https=)
WO (1) WO2018057755A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4122492A1 (en) 2015-02-25 2023-01-25 Memorial Sloan Kettering Cancer Center Use of inactivated nonreplicating modified vaccinia virus ankara (mva)as monoimmunotherapy or in combination with immune checkpoint blocking agents for solid tumors
KR20180006916A (ko) 2015-04-17 2018-01-19 메모리얼 슬로안-케터링 캔서 센터 고형 종양에 대한 면역치료제로서 mva 또는 mva델타e3l의 용도
CN109152827B (zh) 2016-02-25 2023-07-21 纪念斯隆凯特琳癌症中心 重组mva或表达人flt3l的mvaδe3l及其作为抗固体肿瘤的免疫治疗剂的用途
JP7025339B2 (ja) 2016-02-25 2022-02-24 メモリアル スローン ケタリング キャンサー センター 癌免疫療法のための、チミジンキナーゼの欠失を伴い、ヒトflt3lまたはgm-csfの発現を伴うかまたは伴わない、複製可能な弱毒化ワクシニアウイルス
US11345896B2 (en) 2016-11-02 2022-05-31 David Evans Synthetic chimeric poxviruses
EP3621646A4 (en) 2017-05-12 2021-06-02 Memorial Sloan Kettering Cancer Center VACCINIA VIRUS MUTANTS FOR CANCER IMMUNOTHERAPY
EP3973973A1 (en) 2017-10-31 2022-03-30 KaliVir Immunotherapeutics, Inc. Platform oncolytic vector for systemic delivery
CN117004573A (zh) * 2017-12-13 2023-11-07 苏州康聚生物科技有限公司 一种包含肿瘤抗原识别受体的免疫细胞及其应用
WO2019143201A1 (ko) * 2018-01-19 2019-07-25 코오롱생명과학 주식회사 재조합 백시니아 바이러스 및 이를 포함하는 약학 조성물
BR112020022181A2 (pt) 2018-05-02 2021-02-09 Tonix Pharma Holdings Limited vírus vaccinia quimérico sintético
BR112021004692A2 (pt) 2018-09-15 2021-06-08 Memorial Sloan Kettering Cancer Center poxvírus recombinantes para imunoterapia de câncer
US20220288143A1 (en) * 2019-08-29 2022-09-15 Bionoxx Inc. Pharmaceutical composition for treating cancer, comprising vaccinia virus and granulopoiesis inhibitor as active ingredients
CA3197371A1 (en) 2020-11-19 2022-05-27 Kalivir Immunotherapeutics, Inc. Oncolytic immunotherapy by tumor micro-environment remodeling
EP4329786A4 (en) 2021-04-30 2024-12-11 KaliVir Immunotherapeutics, Inc. Oncolytic viruses for modified mhc expression
AU2023363981A1 (en) * 2022-10-19 2025-05-01 Kalivir Immunotherapeutics, Inc. Nucleic acids encoding tgf-beta inhibitor and il-12 and uses thereof
WO2025184411A1 (en) 2024-02-27 2025-09-04 Calidi Biotherapeutics (Nevada), Inc. Serum-resistant eev viruses and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2269619A1 (en) 2002-08-12 2011-01-05 Jennerex Biotherapeutics ULC Methods and compositions concerning poxviruses and cancer
GB0226251D0 (en) * 2002-11-11 2002-12-18 San Raffaele Centro Fond Acetylated protein
CA2882022A1 (en) 2003-09-11 2005-03-24 Walter Newman Monoclonal antibodies against hmgb1
US20090136917A1 (en) * 2007-10-25 2009-05-28 Szalay Aladar A Systems and methods for viral therapy
US8313896B2 (en) * 2008-04-04 2012-11-20 The General Hospital Corporation Oncolytic herpes simplex virus immunotherapy in the treatment of brain cancer
WO2012036215A1 (ja) * 2010-09-17 2012-03-22 Taniguchi Tadatsugu Hmgbタンパクによって仲介される免疫応答の活性化の抑制剤及びスクリーニング方法
CN114262690A (zh) 2011-04-15 2022-04-01 吉恩勒克斯公司 减毒的痘苗病毒的克隆毒株及其使用方法
EP2703487B1 (en) 2011-04-26 2018-06-27 Genomix Co., Ltd. Peptide for inducing regeneration of tissue and use thereof
FI20115914A7 (fi) 2011-09-16 2013-03-17 Oncos Therapeutics Ltd Muunnettu onkolyyttinen virus
DK3036329T3 (da) * 2013-08-22 2021-01-11 Univ Pittsburgh Commonwealth Sys Higher Education Immunonkolytiske terapier

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