JP2019528081A - 子宮内膜症についてのバイオマーカーとしてのマイクロｒｎａ - Google Patents

子宮内膜症についてのバイオマーカーとしてのマイクロｒｎａ Download PDF

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JP2019528081A
JP2019528081A JP2019511953A JP2019511953A JP2019528081A JP 2019528081 A JP2019528081 A JP 2019528081A JP 2019511953 A JP2019511953 A JP 2019511953A JP 2019511953 A JP2019511953 A JP 2019511953A JP 2019528081 A JP2019528081 A JP 2019528081A
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mirna
endometriosis
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JP2019528081A5 (enExample
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テイラー ヒュー
テイラー ヒュー
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Yale University
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/364—Endometriosis, i.e. non-malignant disorder in which functioning endometrial tissue is present outside the uterine cavity

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
JP2019511953A 2016-08-30 2017-08-30 子宮内膜症についてのバイオマーカーとしてのマイクロｒｎａ Pending JP2019528081A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022147738A JP2022188086A (ja) 2016-08-30 2022-09-16 子宮内膜症についてのバイオマーカーとしてのマイクロｒｎａ

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662381130P 2016-08-30 2016-08-30
US62/381,130 2016-08-30
PCT/US2017/049284 WO2018044979A1 (en) 2016-08-30 2017-08-30 Micrornas as biomarkers for endometriosis

Related Child Applications (1)

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JP2019528081A5 JP2019528081A5 (enExample) 2020-10-08

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JP2022147738A Pending JP2022188086A (ja) 2016-08-30 2022-09-16 子宮内膜症についてのバイオマーカーとしてのマイクロｒｎａ

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US (3) US10982282B2 (enExample)
EP (1) EP3506912B1 (enExample)
JP (2) JP2019528081A (enExample)
KR (1) KR20190057305A (enExample)
CN (1) CN109890394A (enExample)
AU (1) AU2017319325A1 (enExample)
BR (1) BR112019004075A2 (enExample)
CA (1) CA3035429A1 (enExample)
MX (1) MX2019002425A (enExample)
SG (2) SG10202102509TA (enExample)
WO (1) WO2018044979A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021172676A1 (ko) * 2020-02-28 2021-09-02 차의과학대학교 산학협력단 난소 예비력 바이오마커 및 이의 용도
JP2022063860A (ja) * 2020-10-12 2022-04-22 学校法人近畿大学 ホウ素化合物およびその製造方法

Families Citing this family (18)

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EP3122905B1 (en) 2014-03-27 2020-09-09 Yale University Circulating micrornas as biomarkers for endometriosis
MX2019002425A (es) 2016-08-30 2019-08-16 Univ Yale Micro ácidos ribonucleicos como biomarcadores para la endometriosis.
KR20200049824A (ko) * 2017-08-30 2020-05-08 닷 레버러토리즈, 인크. 자궁내막증의 검출 및 치료를 위한 방법 및 조성물
EP3820483A4 (en) * 2018-07-13 2023-03-01 Yale University COMPOSITIONS AND METHODS FOR THE TREATMENT OF ENDOMETRIOSIS
KR102089559B1 (ko) * 2018-08-31 2020-03-16 차의과학대학교 산학협력단 난소의 fsh에 대한 반응성의 진단 또는 예측용 바이오마커 및 이의 용도
US11315660B2 (en) 2018-10-31 2022-04-26 Dot Laboratories, Inc. Method of detecting and treating endometriosis in a female subject
EP3873487A4 (en) * 2018-10-31 2022-08-03 Yale University QUANTITATIVE ALGORITHM FOR ENDOMETRIOSIS
WO2020146544A1 (en) * 2019-01-09 2020-07-16 Research Institute At Nationwide Children's Hospital A novel method for monitoring endometriosis and associated disorders
WO2020179895A1 (ja) 2019-03-07 2020-09-10 東レ株式会社 子宮平滑筋肉腫の検出のためのキット、デバイス及び方法
ES2787725A1 (es) * 2019-04-15 2020-10-16 Univ Granada Metodo de obtencion de datos utiles para diagnosticar telangiectasia hemorragica hereditaria
CN110144394A (zh) * 2019-04-18 2019-08-20 辽宁省肿瘤医院 一种子宫内膜异位症诊断、预后标志物及其应用
BR112022000172A2 (pt) * 2019-07-22 2022-02-22 Hoffmann La Roche Métodos para avaliar se uma paciente tem endometriose, para selecionar uma paciente para terapia e para monitorar uma paciente
WO2021013781A1 (en) * 2019-07-22 2021-01-28 F. Hoffmann-La Roche Ag Substance p as blood biomarker for the non-invasive diagnosis of endometriosis
KR20220024782A (ko) * 2019-07-22 2022-03-03 에프. 호프만-라 로슈 아게 자궁내막증의 비침습적 진단을 위한 혈액 바이오마커로서의 s100a8
US11965879B2 (en) 2019-08-23 2024-04-23 Mcmaster University Method for diagnosing and assessing endometriosis
KR102242639B1 (ko) * 2020-01-28 2021-04-21 고려대학교 산학협력단 간 섬유화 진단용 바이오마커 miRNA4668-5p
CN111909997B (zh) 2020-09-09 2021-09-28 上海交通大学 miRNA标志物在制备奥氮平治疗精神分裂症疗效评估方面的产品中的应用及试剂盒
KR20240084586A (ko) * 2022-12-06 2024-06-14 연세대학교 산학협력단 자궁내막증 진단용 조성물

Citations (7)

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US20140024590A1 (en) * 2011-02-18 2014-01-23 Yale University KRAS-Variant And Endometriosis
JP2014513521A (ja) * 2011-01-26 2014-06-05 セファイド 肺癌を検出する方法
JP2015504655A (ja) * 2011-12-16 2015-02-16 ジェネトン 筋ジストロフィーの診断および治療経過観察の方法
WO2015073972A1 (en) * 2013-11-18 2015-05-21 Diamir, Llc METHODS OF USING mIRNAs FROM BODILY FLUIDS FOR DETECTION AND MONITORING OF PARKINSON'S DISEASE (PD)
WO2015128671A1 (en) * 2014-02-27 2015-09-03 Queen Mary University Of London Biomarkers for endometriosis
EP2924126A1 (en) * 2014-03-28 2015-09-30 Reproduktiivmeditsiini TAK AS Method for using microRNA (miRNA) for detection of endometriosis
WO2015148919A2 (en) * 2014-03-27 2015-10-01 Yale University Circulating micrornas as biomarkers for endometriosis

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EP3873487A4 (en) 2018-10-31 2022-08-03 Yale University QUANTITATIVE ALGORITHM FOR ENDOMETRIOSIS
US11315660B2 (en) 2018-10-31 2022-04-26 Dot Laboratories, Inc. Method of detecting and treating endometriosis in a female subject
CN114402083A (zh) 2019-04-29 2022-04-26 耶鲁大学 用于检测子宫内膜异位症的分类器

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US20140024590A1 (en) * 2011-02-18 2014-01-23 Yale University KRAS-Variant And Endometriosis
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WO2015073972A1 (en) * 2013-11-18 2015-05-21 Diamir, Llc METHODS OF USING mIRNAs FROM BODILY FLUIDS FOR DETECTION AND MONITORING OF PARKINSON'S DISEASE (PD)
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WO2015148919A2 (en) * 2014-03-27 2015-10-01 Yale University Circulating micrornas as biomarkers for endometriosis
EP2924126A1 (en) * 2014-03-28 2015-09-30 Reproduktiivmeditsiini TAK AS Method for using microRNA (miRNA) for detection of endometriosis

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021172676A1 (ko) * 2020-02-28 2021-09-02 차의과학대학교 산학협력단 난소 예비력 바이오마커 및 이의 용도
JP2022063860A (ja) * 2020-10-12 2022-04-22 学校法人近畿大学 ホウ素化合物およびその製造方法

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Publication number Publication date
CA3035429A1 (en) 2018-03-08
CN109890394A (zh) 2019-06-14
US20190276893A1 (en) 2019-09-12
EP3506912A1 (en) 2019-07-10
US20210180134A1 (en) 2021-06-17
US11220713B2 (en) 2022-01-11
EP3506912B1 (en) 2024-04-03
US12077803B2 (en) 2024-09-03
KR20190057305A (ko) 2019-05-28
US10982282B2 (en) 2021-04-20
BR112019004075A2 (pt) 2019-05-28
WO2018044979A1 (en) 2018-03-08
SG10202102509TA (en) 2021-04-29
AU2017319325A1 (en) 2019-03-21
JP2022188086A (ja) 2022-12-20
MX2019002425A (es) 2019-08-16
US20220049312A1 (en) 2022-02-17
SG11201901834WA (en) 2019-03-28
EP3506912A4 (en) 2020-08-19

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