|
JP4231559B2
(ja)
|
1997-04-23 |
2009-03-04 |
オリザ油化株式会社 |
リポキシゲナーゼ阻害剤
|
|
TR200003429T2
(tr)
|
1998-05-26 |
2001-07-23 |
Warner-Lambert Company |
Hücresel çoğalma inhibitörleri olarak bisiklik pirimidinler ve bisiklik 3,4-dihidropirimidinler.
|
|
HK1041483B
(zh)
*
|
1998-10-23 |
2004-12-24 |
霍夫曼-拉罗奇有限公司 |
雙環氮雜環
|
|
WO2003090688A2
(en)
|
2002-04-24 |
2003-11-06 |
Van Andel Research Institute |
Enhancement of human epidermal melanogenesis
|
|
US7084270B2
(en)
|
2002-08-14 |
2006-08-01 |
Hoffman-La Roche Inc. |
Pyrimido compounds having antiproliferative activity
|
|
DE10239042A1
(de)
|
2002-08-21 |
2004-03-04 |
Schering Ag |
Makrozyclische Pyrimidine, deren Herstellung und Verwendung als Arzneimittel
|
|
WO2004018669A1
(ja)
|
2002-08-21 |
2004-03-04 |
Proteinexpress Co., Ltd. |
塩誘導性キナーゼ2及びその用途
|
|
US7112676B2
(en)
*
|
2002-11-04 |
2006-09-26 |
Hoffmann-La Roche Inc. |
Pyrimido compounds having antiproliferative activity
|
|
JP2006508997A
(ja)
|
2002-11-28 |
2006-03-16 |
シエーリング アクチエンゲゼルシャフト |
Chk−、Pdk−およびAkt−阻害性ピリミジン、それらの製造および薬剤としての使用
|
|
WO2004089955A1
(en)
*
|
2003-04-10 |
2004-10-21 |
F.Hoffmann-La Roche Ag |
Pyrimido compounds
|
|
US7504396B2
(en)
|
2003-06-24 |
2009-03-17 |
Amgen Inc. |
Substituted heterocyclic compounds and methods of use
|
|
US7442698B2
(en)
|
2003-07-24 |
2008-10-28 |
Amgen Inc. |
Substituted heterocyclic compounds and methods of use
|
|
WO2005011597A2
(en)
*
|
2003-07-29 |
2005-02-10 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
|
RU2401265C2
(ru)
|
2004-06-10 |
2010-10-10 |
Айрм Ллк |
Соединения и композиции в качестве ингибиторов протеинкиназы
|
|
GB0512324D0
(en)
|
2005-06-16 |
2005-07-27 |
Novartis Ag |
Organic compounds
|
|
JP2008510690A
(ja)
|
2004-08-31 |
2008-04-10 |
エフ.ホフマン−ラ ロシュ アーゲー |
3−フェニル−ジヒドロピリミド[4,5−d]ピリミジノンのアミド誘導体、これらの製造、及び医薬品としての使用
|
|
WO2006024545A1
(en)
|
2004-09-03 |
2006-03-09 |
Stichting Voor De Technische Wetenschappen |
Fused bicyclic natural compounds and their use as inhibitors of parp and parp-mediated inflammatory processes
|
|
ATE519759T1
(de)
|
2004-12-30 |
2011-08-15 |
Exelixis Inc |
Pyrimidinderivate als kinasemodulatoren und anwendungsverfahren
|
|
US20080096905A1
(en)
|
2005-03-25 |
2008-04-24 |
Glaxo Group Limited |
Process For Preparing Pyrido[2,3-D]Pyrimidin-7-One And 3,4-Dihydropyrimido{4,5-D}Pyrimidin-2(1H)-One Derivatives
|
|
EP1899344A1
(en)
*
|
2005-06-10 |
2008-03-19 |
Irm, Llc |
Compounds that maintain pluripotency of embryonic stem cells
|
|
GEP20105074B
(en)
|
2005-12-21 |
2010-09-10 |
Novartis Ag |
Pyrimidinyl aryl urea derivatives being fgf inhibitors
|
|
MX2008014618A
(es)
*
|
2006-05-15 |
2008-11-28 |
Irm Llc |
Composiciones y metodos para inhibidores de cinasas del receptor fgf.
|
|
WO2008060248A1
(en)
|
2006-11-15 |
2008-05-22 |
S*Bio Pte Ltd. |
Indole sustituted pyrimidines and use thereof in the treatment of cancer
|
|
EA019869B1
(ru)
|
2007-11-28 |
2014-06-30 |
Дана Фарбер Кансер Инститьют, Инк. |
Низкомолекулярные миристатные ингибиторы тирозинкиназы bcr-abl и способы их применения
|
|
US20100056524A1
(en)
|
2008-04-02 |
2010-03-04 |
Mciver Edward Giles |
Compound
|
|
WO2009152027A1
(en)
|
2008-06-12 |
2009-12-17 |
Merck & Co., Inc. |
5,7-dihydro-6h-pyrrolo[2,3-d]pyrimidin-6-one derivatives for mark inhibition
|
|
JP2011530511A
(ja)
|
2008-08-05 |
2011-12-22 |
メルク・シャープ・エンド・ドーム・コーポレイション |
治療用化合物
|
|
AU2009325400A1
(en)
*
|
2008-12-12 |
2010-06-17 |
Msd K.K. |
Dihydropyrimidopyrimidine derivatives
|
|
AU2010306803A1
(en)
|
2009-10-14 |
2012-05-03 |
Bristol-Myers Squibb Company |
Compounds for the treatment of hepatitis C
|
|
CN102816162B
(zh)
|
2011-06-10 |
2016-04-27 |
中国科学院广州生物医药与健康研究院 |
嘧啶并嘧啶酮类化合物及其药用组合物和应用
|
|
BR112014007622A2
(pt)
|
2011-09-30 |
2017-04-04 |
Oncodesign Sa |
inibidores de flt3 cinase macrocíclicos
|
|
US9382239B2
(en)
|
2011-11-17 |
2016-07-05 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of c-Jun-N-terminal kinase (JNK)
|
|
GB201204384D0
(en)
|
2012-03-13 |
2012-04-25 |
Univ Dundee |
Anti-flammatory agents
|
|
MX371331B
(es)
|
2012-04-24 |
2020-01-27 |
Vertex Pharma |
Inhibidores de la proteina cinasa dependiente de acido desoxirribonucleico(adn-pk).
|
|
GB201212960D0
(en)
*
|
2012-07-20 |
2012-09-05 |
Common Services Agency |
Erythroid production
|
|
JP5683634B2
(ja)
*
|
2012-11-28 |
2015-03-11 |
株式会社ショーワ |
圧力緩衝装置
|
|
US9260426B2
(en)
|
2012-12-14 |
2016-02-16 |
Arrien Pharmaceuticals Llc |
Substituted 1H-pyrrolo [2, 3-b] pyridine and 1H-pyrazolo [3, 4-b] pyridine derivatives as salt inducible kinase 2 (SIK2) inhibitors
|
|
WO2014138485A1
(en)
*
|
2013-03-08 |
2014-09-12 |
Irm Llc |
Ex vivo production of platelets from hematopoietic stem cells and the product thereof
|
|
CN105307657B
(zh)
*
|
2013-03-15 |
2020-07-10 |
西建卡尔有限责任公司 |
杂芳基化合物和其用途
|
|
AU2014230125A1
(en)
|
2013-03-15 |
2015-10-29 |
Oncodesign S.A. |
Macrocyclic salt-inducible kinase inhibitors
|
|
US9783504B2
(en)
|
2013-07-09 |
2017-10-10 |
Dana-Farber Cancer Institute, Inc. |
Kinase inhibitors for the treatment of disease
|
|
CN104418860B
(zh)
*
|
2013-08-20 |
2016-09-07 |
中国科学院广州生物医药与健康研究院 |
嘧啶并杂环类化合物及其药用组合物和应用
|
|
US10457691B2
(en)
|
2014-07-21 |
2019-10-29 |
Dana-Farber Cancer Institute, Inc. |
Macrocyclic kinase inhibitors and uses thereof
|
|
AU2015292818B2
(en)
|
2014-07-21 |
2020-01-16 |
Dana-Farber Cancer Institute, Inc. |
Imidazolyl kinase inhibitors and uses thereof
|
|
CA2955082A1
(en)
|
2014-08-08 |
2016-02-11 |
Dana-Farber Cancer Institute, Inc. |
Uses of salt-inducible kinase (sik) inhibitors
|
|
KR101850282B1
(ko)
|
2014-11-26 |
2018-05-31 |
한국과학기술연구원 |
단백질 키나아제 저해제로 유용한 헤테로아릴아민 유도체
|
|
CN104482860B
(zh)
|
2014-12-05 |
2017-10-31 |
浙江大学宁波理工学院 |
鱼类形态参数自动测量装置和方法
|
|
WO2018009544A1
(en)
*
|
2016-07-05 |
2018-01-11 |
The Broad Institute, Inc. |
Bicyclic urea kinase inhibitors and uses thereof
|
|
US11241435B2
(en)
|
2016-09-16 |
2022-02-08 |
The General Hospital Corporation |
Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis
|
|
AU2018226771B2
(en)
*
|
2017-02-28 |
2023-11-23 |
Dana-Farber Cancer Institute, Inc. |
Uses of pyrimidopyrimidinones as SIK inhibitors
|