JP2019527209A5 - - Google Patents
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- Publication number
- JP2019527209A5 JP2019527209A5 JP2018569157A JP2018569157A JP2019527209A5 JP 2019527209 A5 JP2019527209 A5 JP 2019527209A5 JP 2018569157 A JP2018569157 A JP 2018569157A JP 2018569157 A JP2018569157 A JP 2018569157A JP 2019527209 A5 JP2019527209 A5 JP 2019527209A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- natural number
- drug conjugate
- group
- null
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1611405.0A GB2551979A (en) | 2016-06-30 | 2016-06-30 | Cleavable polymer drug conjugates |
| GB1611405.0 | 2016-06-30 | ||
| PCT/IB2017/053567 WO2018002761A1 (en) | 2016-06-30 | 2017-06-15 | Cleavable polymer drug conjugates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019527209A JP2019527209A (ja) | 2019-09-26 |
| JP2019527209A5 true JP2019527209A5 (enExample) | 2020-07-27 |
| JP6937329B2 JP6937329B2 (ja) | 2021-09-22 |
Family
ID=56891421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018569157A Active JP6937329B2 (ja) | 2016-06-30 | 2017-06-15 | 切断可能なポリマー薬物コンジュゲート |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20190321479A1 (enExample) |
| EP (2) | EP4260874A1 (enExample) |
| JP (1) | JP6937329B2 (enExample) |
| KR (3) | KR20230035709A (enExample) |
| CN (1) | CN109475637A (enExample) |
| AU (1) | AU2017286869B2 (enExample) |
| CA (1) | CA3029318A1 (enExample) |
| DK (1) | DK3478323T3 (enExample) |
| EA (1) | EA038984B1 (enExample) |
| ES (1) | ES2966774T3 (enExample) |
| FI (1) | FI3478323T3 (enExample) |
| GB (1) | GB2551979A (enExample) |
| HR (1) | HRP20231642T1 (enExample) |
| HU (1) | HUE064705T2 (enExample) |
| IL (3) | IL321408A (enExample) |
| MX (2) | MX2019000277A (enExample) |
| PL (1) | PL3478323T3 (enExample) |
| PT (1) | PT3478323T (enExample) |
| WO (1) | WO2018002761A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8765432B2 (en) | 2009-12-18 | 2014-07-01 | Oligasis, Llc | Targeted drug phosphorylcholine polymer conjugates |
| GB2556055B (en) | 2016-11-16 | 2022-03-23 | Rs Arastirma Egitim Danismanlik Ilac Sanayi Ticaret Ltd Sti | Self-assembled diblock copolymers composed of pegmema and drug bearing polymeric segments |
| US12150996B2 (en) * | 2017-11-17 | 2024-11-26 | Centre National De La Recherche Scientifique | Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof |
| CN108752507A (zh) * | 2018-05-12 | 2018-11-06 | 辽宁大学 | 一种酶敏感和氧化还原敏感双重响应型共聚物及其制备方法和应用 |
| TR201911542A2 (tr) * | 2019-07-30 | 2021-02-22 | Bogazici Ueniversitesi | Anti̇kor-poli̇mer konjugatlari |
| JP2022549680A (ja) * | 2019-09-26 | 2022-11-28 | スターファーマ ピーティーワイ エルティーディー | 治療用デンドリマー |
| CN112608364B (zh) * | 2020-12-09 | 2023-08-29 | 四川瀛瑞医药科技有限公司 | 一种果胶-阿霉素轭合物及其中间体的制备方法 |
| CN115010913B (zh) * | 2022-06-17 | 2023-05-26 | 广东工业大学 | 一种pH/还原双重响应聚合物胶束及其制备方法与应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19636889A1 (de) | 1996-09-11 | 1998-03-12 | Felix Dr Kratz | Antineoplastisch wirkende Transferrin- und Albuminkonjugate zytostatischer Verbindungen aus der Gruppe der Anthrazykline, Alkylantien, Antimetabolite und Cisplatin-Analoga und diese enthaltende Arzneimittel |
| ATE317703T1 (de) | 1997-06-12 | 2006-03-15 | Innovata Plc | Polymer-wirkstoff-konjugate zur behandlung von krebs |
| CN1308347C (zh) | 1999-04-28 | 2007-04-04 | 德克萨斯大学董事会 | 用于通过选择性抑制vegf来治疗癌症的组合物和方法 |
| US20030215395A1 (en) | 2002-05-14 | 2003-11-20 | Lei Yu | Controllably degradable polymeric biomolecule or drug carrier and method of synthesizing said carrier |
| CZ2005558A3 (cs) * | 2005-09-05 | 2007-04-04 | Zentiva, A. S. | Zpusob prípravy polymerních konjugátu doxorubicinu s pH-rízeným uvolnováním léciva |
| US8017141B2 (en) * | 2006-12-15 | 2011-09-13 | Advanced Cardiovascular Systems, Inc. | Coatings of acrylamide-based copolymers |
| AU2009302387B2 (en) * | 2008-10-07 | 2014-12-04 | Rexahn Pharmaceuticals, Inc | HPMA - docetaxel or gemcitabine conjugates and uses therefore |
| CZ303072B6 (cs) * | 2009-02-13 | 2012-03-21 | Zentiva, K.S. | Polymerní konjugáty paclitaxelu a docetaxelu s pH rízeným uvolnováním kancerostatika |
| BR112012008772A2 (pt) * | 2009-10-13 | 2017-06-20 | Rexahn Pharmaceuticals Inc | sistemas poliméricos para a liberação de agentes anti-câncer |
| WO2012014003A1 (en) * | 2010-07-28 | 2012-02-02 | Corning Incorporated | Pre-polymer preparations for cell culture coatings |
| WO2014152451A2 (en) * | 2013-03-14 | 2014-09-25 | University Of Rochester | Compositions and methods for controlled localized delivery of bone forming therapeutic agents |
| CN105168230B (zh) * | 2015-09-02 | 2019-01-22 | 上海市普陀区中心医院 | 一种具有内涵体逃逸功能的肿瘤靶向前药及其纳米制剂和制备方法 |
-
2016
- 2016-06-30 GB GB1611405.0A patent/GB2551979A/en not_active Withdrawn
-
2017
- 2017-06-15 MX MX2019000277A patent/MX2019000277A/es unknown
- 2017-06-15 CA CA3029318A patent/CA3029318A1/en active Pending
- 2017-06-15 PT PT177339066T patent/PT3478323T/pt unknown
- 2017-06-15 KR KR1020237007512A patent/KR20230035709A/ko not_active Ceased
- 2017-06-15 DK DK17733906.6T patent/DK3478323T3/da active
- 2017-06-15 ES ES17733906T patent/ES2966774T3/es active Active
- 2017-06-15 CN CN201780045704.2A patent/CN109475637A/zh active Pending
- 2017-06-15 PL PL17733906.6T patent/PL3478323T3/pl unknown
- 2017-06-15 IL IL321408A patent/IL321408A/en unknown
- 2017-06-15 KR KR1020197002227A patent/KR102539137B1/ko active Active
- 2017-06-15 EA EA201990142A patent/EA038984B1/ru unknown
- 2017-06-15 FI FIEP17733906.6T patent/FI3478323T3/fi active
- 2017-06-15 US US16/314,328 patent/US20190321479A1/en active Pending
- 2017-06-15 HU HUE17733906A patent/HUE064705T2/hu unknown
- 2017-06-15 WO PCT/IB2017/053567 patent/WO2018002761A1/en not_active Ceased
- 2017-06-15 HR HRP20231642TT patent/HRP20231642T1/hr unknown
- 2017-06-15 AU AU2017286869A patent/AU2017286869B2/en active Active
- 2017-06-15 EP EP23178285.5A patent/EP4260874A1/en active Pending
- 2017-06-15 KR KR1020257017360A patent/KR20250084234A/ko active Pending
- 2017-06-15 JP JP2018569157A patent/JP6937329B2/ja active Active
- 2017-06-15 IL IL263965A patent/IL263965B2/en unknown
- 2017-06-15 EP EP17733906.6A patent/EP3478323B1/en active Active
-
2019
- 2019-01-07 MX MX2024000877A patent/MX2024000877A/es unknown
-
2023
- 2023-05-01 IL IL302564A patent/IL302564B2/en unknown
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