JP2019526560A5 - - Google Patents

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Publication number
JP2019526560A5
JP2019526560A5 JP2019510659A JP2019510659A JP2019526560A5 JP 2019526560 A5 JP2019526560 A5 JP 2019526560A5 JP 2019510659 A JP2019510659 A JP 2019510659A JP 2019510659 A JP2019510659 A JP 2019510659A JP 2019526560 A5 JP2019526560 A5 JP 2019526560A5
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JP
Japan
Prior art keywords
cancer
substituted
tumor
arylalkyl
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019510659A
Other languages
English (en)
Japanese (ja)
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JP2019526560A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/048581 external-priority patent/WO2018039544A1/en
Publication of JP2019526560A publication Critical patent/JP2019526560A/ja
Publication of JP2019526560A5 publication Critical patent/JP2019526560A5/ja
Pending legal-status Critical Current

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JP2019510659A 2016-08-25 2017-08-25 グルタミナーゼ阻害剤との併用療法 Pending JP2019526560A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662379604P 2016-08-25 2016-08-25
US62/379,604 2016-08-25
PCT/US2017/048581 WO2018039544A1 (en) 2016-08-25 2017-08-25 Combination therapy with glutaminase inhibitors

Publications (2)

Publication Number Publication Date
JP2019526560A JP2019526560A (ja) 2019-09-19
JP2019526560A5 true JP2019526560A5 (OSRAM) 2020-10-01

Family

ID=61240223

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019510659A Pending JP2019526560A (ja) 2016-08-25 2017-08-25 グルタミナーゼ阻害剤との併用療法

Country Status (12)

Country Link
US (2) US10278968B2 (OSRAM)
EP (1) EP3503886A4 (OSRAM)
JP (1) JP2019526560A (OSRAM)
KR (1) KR20190040302A (OSRAM)
CN (1) CN110139649A (OSRAM)
AU (1) AU2017315446A1 (OSRAM)
BR (1) BR112019003533A2 (OSRAM)
CA (1) CA3034890A1 (OSRAM)
EA (1) EA201990567A1 (OSRAM)
MX (1) MX2019002108A (OSRAM)
SG (1) SG11201901389XA (OSRAM)
WO (1) WO2018039544A1 (OSRAM)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2899461T3 (es) 2012-11-16 2022-03-11 Calithera Biosciences Inc Inhibidores heterocíclicos de glutaminasa
BR112017002403A2 (pt) 2014-08-07 2017-12-05 Calithera Biosciences Inc formas de cristais de inibidores de glutaminase
CA2981762A1 (en) 2015-04-06 2016-10-13 Calithera Biosciences, Inc. Treatment of lung cancer with inhibitors of glutaminase
CN108601767A (zh) 2015-10-05 2018-09-28 卡利泰拉生物科技公司 用谷氨酰胺酶抑制剂和免疫肿瘤学药剂的组合疗法
JP2019524852A (ja) 2016-08-25 2019-09-05 キャリセラ バイオサイエンシーズ, インコーポレイテッド グルタミナーゼ阻害剤を用いる併用療法
US10278968B2 (en) 2016-08-25 2019-05-07 Calithera Biosciences, Inc. Combination therapy with glutaminase inhibitors
US11590122B2 (en) 2021-02-19 2023-02-28 Slayback Pharma Llc Pharmaceutical compositions of cabozantinib
KR20230001587A (ko) * 2021-06-28 2023-01-05 연세대학교 산학협력단 암의 예방 또는 치료용 약학 조성물

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US6451828B1 (en) 2000-08-10 2002-09-17 Elan Pharmaceuticals, Inc. Selective inhibition of glutaminase by bis-thiadiazoles
WO2002076939A2 (en) 2001-02-05 2002-10-03 Exegenics Inc. Cysteine protease inhibitors
JP4885122B2 (ja) 2004-04-15 2012-02-29 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド 癌、器官傷害、および筋肉リハビリテーション/運動過剰訓練についての診断の生物マーカーとしてのタンパク質分解マーカー
US8778410B2 (en) 2008-02-19 2014-07-15 Earnest Medicine Co., Ltd. Oral or enteral composition useful for recovery of physical functions
WO2011143160A2 (en) 2010-05-10 2011-11-17 The Johns Hopkins University Metabolic inhibitor against tumors having an idh mutation
US10064885B2 (en) 2010-07-09 2018-09-04 Massachusetts Institute Of Technology Metabolic gene, enzyme, and flux targets for cancer therapy
US20120302605A1 (en) 2010-11-18 2012-11-29 Deuteria Pharmaceuticals, Llc 3-deutero-pomalidomide
CN103030597B (zh) 2011-09-30 2014-10-01 南昌滨西科技有限公司 肾脏型谷氨酰胺酶抑制剂及其制备方法和用途
ES2761866T3 (es) * 2011-11-21 2020-05-21 Calithera Biosciences Inc Inhibidores heterocíclicos de glutaminasa
US8604016B2 (en) 2011-11-21 2013-12-10 Calithera Biosciences Inc. Heterocyclic inhibitors of glutaminase
KR20150054962A (ko) 2012-09-10 2015-05-20 셀진 코포레이션 국소 진행성 유방암의 치료방법
ES2899461T3 (es) * 2012-11-16 2022-03-11 Calithera Biosciences Inc Inhibidores heterocíclicos de glutaminasa
SG11201504022RA (en) 2012-11-21 2015-06-29 Agios Pharmaceuticals Inc Glutamase inhibitors and method of use
WO2014079011A1 (en) * 2012-11-22 2014-05-30 Agios Pharmaceuticals, Inc. Heterocyclic compounds for inhibiting glutaminase and their methods of use
US9029531B2 (en) * 2012-11-22 2015-05-12 Agios Pharmaceuticals, Inc. Compounds and their methods of use
CN105283182A (zh) 2012-12-03 2016-01-27 卡利泰拉生物科技公司 用谷氨酰胺酶的杂环抑制剂治疗癌症
EP3060251A4 (en) 2013-10-25 2017-12-06 Pharmacyclics LLC Treatment using bruton's tyrosine kinase inhibitors and immunotherapy
WO2015061432A1 (en) 2013-10-25 2015-04-30 Calithera Biosciences, Inc. Treatment of viral infections with inhibitors of glutaminase
EP3116872A4 (en) 2014-03-14 2017-08-30 Calithera Biosciences, Inc. Combination therapy with glutaminase inhibitors
US10221459B2 (en) 2014-05-13 2019-03-05 Case Western Reserve University Compositions and methods of treating cancer harboring PIKC3A mutations
MX374924B (es) 2014-06-13 2025-03-06 Calithera Biosciences Inc Terapia de combinacion con inhibidores de glutaminasa.
WO2016004418A1 (en) 2014-07-03 2016-01-07 Board Of Regents, University Of Texas System Glutaminase inhibitor therapy
WO2016014890A1 (en) 2014-07-24 2016-01-28 Calithera Biosciences, Inc. Treatment of multiple myeloma with heterocyclic inhibitors of glutaminase
BR112017002403A2 (pt) 2014-08-07 2017-12-05 Calithera Biosciences Inc formas de cristais de inibidores de glutaminase
US10245254B2 (en) 2014-10-03 2019-04-02 University of Pittsburgh—of the Commonwealth System of Higher Education Glutaminase inhibitors
WO2016077632A2 (en) 2014-11-13 2016-05-19 Buck Institute For Research On Aging Inhibition of proline catabolism for the treatment of cancer and other therapeutic applications
US20160287564A1 (en) 2015-03-30 2016-10-06 Calithera Biosciences, Inc. Methods of administering glutaminase inhibitors
CA2981762A1 (en) 2015-04-06 2016-10-13 Calithera Biosciences, Inc. Treatment of lung cancer with inhibitors of glutaminase
US10278968B2 (en) 2016-08-25 2019-05-07 Calithera Biosciences, Inc. Combination therapy with glutaminase inhibitors
JP2019524852A (ja) 2016-08-25 2019-09-05 キャリセラ バイオサイエンシーズ, インコーポレイテッド グルタミナーゼ阻害剤を用いる併用療法
US20180055825A1 (en) 2016-08-25 2018-03-01 Yu Liang Treatment of cancer with inhibitors of glutaminase

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