JP2019526257A5 - - Google Patents
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- JP2019526257A5 JP2019526257A5 JP2019511456A JP2019511456A JP2019526257A5 JP 2019526257 A5 JP2019526257 A5 JP 2019526257A5 JP 2019511456 A JP2019511456 A JP 2019511456A JP 2019511456 A JP2019511456 A JP 2019511456A JP 2019526257 A5 JP2019526257 A5 JP 2019526257A5
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- 108020004414 DNA Proteins 0.000 claims description 229
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- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 52
- 238000012360 testing method Methods 0.000 claims description 34
- 230000003321 amplification Effects 0.000 claims description 25
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 25
- 108090000623 proteins and genes Proteins 0.000 claims description 21
- 108091033319 polynucleotide Proteins 0.000 claims description 18
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- 238000012163 sequencing technique Methods 0.000 claims description 14
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 11
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- 206010028980 Neoplasm Diseases 0.000 claims description 9
- 208000037051 Chromosomal Instability Diseases 0.000 claims description 8
- 150000007523 nucleic acids Chemical group 0.000 claims description 8
- 238000001712 DNA sequencing Methods 0.000 claims description 6
- 238000012408 PCR amplification Methods 0.000 claims description 6
- 238000004458 analytical method Methods 0.000 claims description 6
- 239000013610 patient sample Substances 0.000 claims description 6
- 238000000746 purification Methods 0.000 claims description 6
- 208000026350 Inborn Genetic disease Diseases 0.000 claims description 5
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- 238000012935 Averaging Methods 0.000 claims description 4
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- 102000000872 ATM Human genes 0.000 claims description 2
- 108010004586 Ataxia Telangiectasia Mutated Proteins Proteins 0.000 claims description 2
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- 102000012410 DNA Ligases Human genes 0.000 claims description 2
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- 239000003298 DNA probe Substances 0.000 claims description 2
- 102000009095 Fanconi Anemia Complementation Group A protein Human genes 0.000 claims description 2
- 108010087740 Fanconi Anemia Complementation Group A protein Proteins 0.000 claims description 2
- 108010067741 Fanconi Anemia Complementation Group N protein Proteins 0.000 claims description 2
- 102000016627 Fanconi Anemia Complementation Group N protein Human genes 0.000 claims description 2
- 102100034553 Fanconi anemia group J protein Human genes 0.000 claims description 2
- 208000031448 Genomic Instability Diseases 0.000 claims description 2
- 208000028782 Hereditary disease Diseases 0.000 claims description 2
- 102100039999 Histone deacetylase 2 Human genes 0.000 claims description 2
- 101000848171 Homo sapiens Fanconi anemia group J protein Proteins 0.000 claims description 2
- 101001035011 Homo sapiens Histone deacetylase 2 Proteins 0.000 claims description 2
- 101000777277 Homo sapiens Serine/threonine-protein kinase Chk2 Proteins 0.000 claims description 2
- 208000024556 Mendelian disease Diseases 0.000 claims description 2
- 101100015391 Mus musculus Ralgds gene Proteins 0.000 claims description 2
- 239000012661 PARP inhibitor Substances 0.000 claims description 2
- 229940121906 Poly ADP ribose polymerase inhibitor Drugs 0.000 claims description 2
- 108010021757 Polynucleotide 5'-Hydroxyl-Kinase Proteins 0.000 claims description 2
- 102000008422 Polynucleotide 5'-hydroxyl-kinase Human genes 0.000 claims description 2
- 102100031075 Serine/threonine-protein kinase Chk2 Human genes 0.000 claims description 2
- 210000004381 amniotic fluid Anatomy 0.000 claims description 2
- 239000012472 biological sample Substances 0.000 claims description 2
- 239000008280 blood Substances 0.000 claims description 2
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- 239000000203 mixture Substances 0.000 claims 22
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- 238000003745 diagnosis Methods 0.000 description 1
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Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021180899A JP7304393B2 (ja) | 2016-08-25 | 2021-11-05 | Ｄｎａ試料中のゲノムコピー変化の検出方法 |
| JP2023044421A JP2023078336A (ja) | 2016-08-25 | 2023-03-20 | Ｄｎａ試料中のゲノムコピー変化の検出方法 |
| JP2024094503A JP2024107320A (ja) | 2016-08-25 | 2024-06-11 | Ｄｎａ試料中のゲノムコピー変化の検出方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662379593P | 2016-08-25 | 2016-08-25 | |
| US62/379,593 | 2016-08-25 | ||
| US201762481538P | 2017-04-04 | 2017-04-04 | |
| US62/481,538 | 2017-04-04 | ||
| PCT/US2017/048434 WO2018039463A1 (en) | 2016-08-25 | 2017-08-24 | Methods for the detection of genomic copy changes in dna samples |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021180899A Division JP7304393B2 (ja) | 2016-08-25 | 2021-11-05 | Ｄｎａ試料中のゲノムコピー変化の検出方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019526257A JP2019526257A (ja) | 2019-09-19 |
| JP2019526257A5 true JP2019526257A5 (OSRAM) | 2020-08-20 |
| JP7217224B2 JP7217224B2 (ja) | 2023-02-02 |
Family
ID=61245331
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511456A Active JP7217224B2 (ja) | 2016-08-25 | 2017-08-24 | Ｄｎａ試料中のゲノムコピー変化の検出方法 |
| JP2021180899A Active JP7304393B2 (ja) | 2016-08-25 | 2021-11-05 | Ｄｎａ試料中のゲノムコピー変化の検出方法 |
| JP2023044421A Pending JP2023078336A (ja) | 2016-08-25 | 2023-03-20 | Ｄｎａ試料中のゲノムコピー変化の検出方法 |
| JP2024094503A Pending JP2024107320A (ja) | 2016-08-25 | 2024-06-11 | Ｄｎａ試料中のゲノムコピー変化の検出方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021180899A Active JP7304393B2 (ja) | 2016-08-25 | 2021-11-05 | Ｄｎａ試料中のゲノムコピー変化の検出方法 |
| JP2023044421A Pending JP2023078336A (ja) | 2016-08-25 | 2023-03-20 | Ｄｎａ試料中のゲノムコピー変化の検出方法 |
| JP2024094503A Pending JP2024107320A (ja) | 2016-08-25 | 2024-06-11 | Ｄｎａ試料中のゲノムコピー変化の検出方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11319594B2 (OSRAM) |
| EP (2) | EP4667584A2 (OSRAM) |
| JP (4) | JP7217224B2 (OSRAM) |
| KR (2) | KR102850460B1 (OSRAM) |
| CN (2) | CN117286217A (OSRAM) |
| AU (2) | AU2017315769B2 (OSRAM) |
| CA (1) | CA3034649A1 (OSRAM) |
| IL (2) | IL264971B2 (OSRAM) |
| MX (2) | MX2019002093A (OSRAM) |
| NZ (1) | NZ750902A (OSRAM) |
| RU (1) | RU2019108294A (OSRAM) |
| SG (1) | SG11201901371XA (OSRAM) |
| WO (1) | WO2018039463A1 (OSRAM) |
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| AU2017315769B2 (en) | 2016-08-25 | 2024-02-01 | Resolution Bioscience, Inc. | Methods for the detection of genomic copy changes in DNA samples |
| JP2021514663A (ja) * | 2018-03-08 | 2021-06-17 | セント・ジョーンズ・ユニバーシティＳｔ． Ｊｏｈｎｓ Ｕｎｉｖｅｒｓｉｔｙ | 循環性血清無細胞ｄｎａバイオマーカー及び方法 |
| DE202019005627U1 (de) | 2018-04-02 | 2021-05-31 | Grail, Inc. | Methylierungsmarker und gezielte Methylierungssondenpanels |
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| CN111118610A (zh) * | 2018-10-31 | 2020-05-08 | 深圳华大基因股份有限公司 | 用于基因突变高深度测序的基因芯片及其制备方法和应用 |
| CA3118304A1 (en) * | 2018-11-02 | 2020-05-07 | The Regents Of The University Of California | Methods to diagnose and treat cancer using non-human nucleic acids |
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| US20210310067A1 (en) * | 2019-01-24 | 2021-10-07 | Illumina, Inc. | Methods and systems for monitoring organ health and disease |
| JP2022532761A (ja) * | 2019-05-17 | 2022-07-19 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 異数性の迅速検出法 |
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| KR102184277B1 (ko) * | 2020-01-16 | 2020-11-30 | 성균관대학교산학협력단 | 초음파 진단 및 dna 검사 일체형 ai 자가 건강 관리 장치 및 이를 이용한 원격 의료 진단 방법 |
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| US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
| CN113496760B (zh) * | 2020-04-01 | 2024-01-12 | 深圳华大基因科技服务有限公司 | 基于第三代测序的多倍体基因组组装方法和装置 |
| CN113113085B (zh) * | 2021-03-15 | 2022-08-19 | 杭州杰毅生物技术有限公司 | 基于智能宏基因组测序数据肿瘤检测的分析系统及方法 |
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