JP2019524791A5 - - Google Patents

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JP2019524791A5
JP2019524791A5 JP2019506516A JP2019506516A JP2019524791A5 JP 2019524791 A5 JP2019524791 A5 JP 2019524791A5 JP 2019506516 A JP2019506516 A JP 2019506516A JP 2019506516 A JP2019506516 A JP 2019506516A JP 2019524791 A5 JP2019524791 A5 JP 2019524791A5
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JP
Japan
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group
inhibitor
alkynyl
groups
alkenyl
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JP2019506516A
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JP2019524791A (ja
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Priority claimed from PCT/US2017/045690 external-priority patent/WO2018031445A1/en
Publication of JP2019524791A publication Critical patent/JP2019524791A/ja
Publication of JP2019524791A5 publication Critical patent/JP2019524791A5/ja
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JP2019506516A 2016-08-08 2017-08-07 Ｅ−セレクチンの阻害剤もしくはｃｘｃｒ４の阻害剤との、またはｅ−セレクチンおよびｃｘｃｒ４両方のヘテロ二機能性阻害剤とのｔ細胞チェックポイント阻害剤の組み合わせ Pending JP2019524791A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662372116P 2016-08-08 2016-08-08
US62/372,116 2016-08-08
US201662417045P 2016-11-03 2016-11-03
US62/417,045 2016-11-03
US201662418722P 2016-11-07 2016-11-07
US62/418,722 2016-11-07
PCT/US2017/045690 WO2018031445A1 (en) 2016-08-08 2017-08-07 Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4

Publications (2)

Publication Number Publication Date
JP2019524791A JP2019524791A (ja) 2019-09-05
JP2019524791A5 true JP2019524791A5 (https=) 2020-09-17

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ID=59687019

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JP2019506516A Pending JP2019524791A (ja) 2016-08-08 2017-08-07 Ｅ−セレクチンの阻害剤もしくはｃｘｃｒ４の阻害剤との、またはｅ−セレクチンおよびｃｘｃｒ４両方のヘテロ二機能性阻害剤とのｔ細胞チェックポイント阻害剤の組み合わせ

Country Status (4)

Country Link
US (2) US11433086B2 (https=)
EP (1) EP3497131B1 (https=)
JP (1) JP2019524791A (https=)
WO (1) WO2018031445A1 (https=)

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CA3120690A1 (en) * 2018-11-20 2020-05-28 The Wistar Institute For Anatomy And Biology Methods and compositions for reducing numbers or eliminating hiv-infected cells
WO2020123435A2 (en) * 2018-12-10 2020-06-18 Glycomimetics, Inc. Methods of treating hiv and aids and the elimination of latent reservoirs of hiv infection using selectin, galectin, and siglec antagonists
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CN115666584A (zh) * 2020-05-31 2023-01-31 糖模拟物有限公司 用于减少癌细胞负荷和保护正常血细胞生成的化合物和方法

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