JP2019524748A5 - - Google Patents
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- JP2019524748A5 JP2019524748A5 JP2019502829A JP2019502829A JP2019524748A5 JP 2019524748 A5 JP2019524748 A5 JP 2019524748A5 JP 2019502829 A JP2019502829 A JP 2019502829A JP 2019502829 A JP2019502829 A JP 2019502829A JP 2019524748 A5 JP2019524748 A5 JP 2019524748A5
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- cancer
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- 239000008194 pharmaceutical composition Substances 0.000 claims 26
- 201000011510 cancer Diseases 0.000 claims 19
- 238000002648 combination therapy Methods 0.000 claims 11
- UFNVPOGXISZXJD-JBQZKEIOSA-N eribulin Chemical compound C([C@H]1CC[C@@H]2O[C@@H]3[C@H]4O[C@@H]5C[C@](O[C@H]4[C@H]2O1)(O[C@@H]53)CC[C@@H]1O[C@H](C(C1)=C)CC1)C(=O)C[C@@H]2[C@@H](OC)[C@@H](C[C@H](O)CN)O[C@H]2C[C@@H]2C(=C)[C@H](C)C[C@H]1O2 UFNVPOGXISZXJD-JBQZKEIOSA-N 0.000 claims 11
- 239000003276 histone deacetylase inhibitor Substances 0.000 claims 10
- 229960003649 eribulin Drugs 0.000 claims 9
- 229940121372 histone deacetylase inhibitor Drugs 0.000 claims 9
- 150000003839 salts Chemical class 0.000 claims 9
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- INVTYAOGFAGBOE-UHFFFAOYSA-N entinostat Chemical compound NC1=CC=CC=C1NC(=O)C(C=C1)=CC=C1CNC(=O)OCC1=CC=CN=C1 INVTYAOGFAGBOE-UHFFFAOYSA-N 0.000 claims 4
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- UKLDJPRMSDWDSL-UHFFFAOYSA-L [dibutyl(dodecanoyloxy)stannyl] dodecanoate Chemical compound CCCCCCCCCCCC(=O)O[Sn](CCCC)(CCCC)OC(=O)CCCCCCCCCCC UKLDJPRMSDWDSL-UHFFFAOYSA-L 0.000 claims 1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662364440P | 2016-07-20 | 2016-07-20 | |
| US62/364,440 | 2016-07-20 | ||
| PCT/JP2017/026212 WO2018016563A1 (en) | 2016-07-20 | 2017-07-20 | Use of eribulin and histone deacetylase inhibitors in the treatment of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019524748A JP2019524748A (ja) | 2019-09-05 |
| JP2019524748A5 true JP2019524748A5 (enExample) | 2020-08-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019502829A Withdrawn JP2019524748A (ja) | 2016-07-20 | 2017-07-20 | がんの治療におけるエリブリン及びヒストンデアセチラーゼ阻害剤の使用 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20190282541A1 (enExample) |
| EP (1) | EP3487492A4 (enExample) |
| JP (1) | JP2019524748A (enExample) |
| WO (1) | WO2018016563A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017181141A2 (en) | 2016-04-15 | 2017-10-19 | Novira Therapeutics, Inc. | Combinations and methods comprising a capsid assembly inhibitor |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| US20190046513A1 (en) * | 2017-08-10 | 2019-02-14 | Huya Bioscience International, Llc | Combination therapies of hdac inhibitors and tubulin inhibitors |
| JP7169125B2 (ja) * | 2018-08-29 | 2022-11-10 | 株式会社日立製作所 | 質問回答システム、質問回答処理方法、及び質問回答統合システム |
| EP3877422A4 (en) * | 2018-11-09 | 2022-08-24 | G1 Therapeutics, Inc. | Therapeutic regimens for treatment of cancer using eribulin and selective cdk4/6 inhibitor combinations |
| WO2022048527A1 (zh) * | 2020-09-01 | 2022-03-10 | 深圳微芯生物科技股份有限公司 | 西达本胺联合雌激素受体下调剂治疗乳腺癌的用途 |
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|---|---|---|---|---|
| WO2009067543A2 (en) * | 2007-11-19 | 2009-05-28 | The Regents Of The University Of Colorado | Treatment of histone deacetylase mediated disorders |
| US10226472B2 (en) * | 2011-09-02 | 2019-03-12 | Syndax Pharmaceuticals, Inc. | Methods for the treatment of breast cancer |
| JP2016522188A (ja) * | 2013-05-03 | 2016-07-28 | シンダックス ファーマシューティカルズ，インク． | 癌の処置方法 |
-
2017
- 2017-07-20 US US16/318,198 patent/US20190282541A1/en not_active Abandoned
- 2017-07-20 JP JP2019502829A patent/JP2019524748A/ja not_active Withdrawn
- 2017-07-20 WO PCT/JP2017/026212 patent/WO2018016563A1/en not_active Ceased
- 2017-07-20 EP EP17831079.3A patent/EP3487492A4/en not_active Withdrawn
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