JP2019524748A - がんの治療におけるエリブリン及びヒストンデアセチラーゼ阻害剤の使用 - Google Patents
がんの治療におけるエリブリン及びヒストンデアセチラーゼ阻害剤の使用 Download PDFInfo
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- JP2019524748A JP2019524748A JP2019502829A JP2019502829A JP2019524748A JP 2019524748 A JP2019524748 A JP 2019524748A JP 2019502829 A JP2019502829 A JP 2019502829A JP 2019502829 A JP2019502829 A JP 2019502829A JP 2019524748 A JP2019524748 A JP 2019524748A
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
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- A—HUMAN NECESSITIES
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
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- Organic Chemistry (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| US201662364440P | 2016-07-20 | 2016-07-20 | |
| US62/364,440 | 2016-07-20 | ||
| PCT/JP2017/026212 WO2018016563A1 (en) | 2016-07-20 | 2017-07-20 | Use of eribulin and histone deacetylase inhibitors in the treatment of cancer |
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| JP2019524748A true JP2019524748A (ja) | 2019-09-05 |
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| EP (1) | EP3487492A4 (enExample) |
| JP (1) | JP2019524748A (enExample) |
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| CA3021068A1 (en) | 2016-04-15 | 2017-10-19 | Novira Therapeutics, Inc. | Combinations and methods comprising a capsid assembly inhibitor |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| US20190046513A1 (en) * | 2017-08-10 | 2019-02-14 | Huya Bioscience International, Llc | Combination therapies of hdac inhibitors and tubulin inhibitors |
| JP7169125B2 (ja) * | 2018-08-29 | 2022-11-10 | 株式会社日立製作所 | 質問回答システム、質問回答処理方法、及び質問回答統合システム |
| CN113271977A (zh) * | 2018-11-09 | 2021-08-17 | G1治疗公司 | 使用艾日布林和选择性cdk4/6抑制剂组合治疗癌症的治疗方案 |
| WO2022048527A1 (zh) * | 2020-09-01 | 2022-03-10 | 深圳微芯生物科技股份有限公司 | 西达本胺联合雌激素受体下调剂治疗乳腺癌的用途 |
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| JP2016522188A (ja) * | 2013-05-03 | 2016-07-28 | シンダックス ファーマシューティカルズ，インク． | 癌の処置方法 |
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- 2017-07-20 US US16/318,198 patent/US20190282541A1/en not_active Abandoned
- 2017-07-20 EP EP17831079.3A patent/EP3487492A4/en not_active Withdrawn
- 2017-07-20 WO PCT/JP2017/026212 patent/WO2018016563A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP3487492A4 (en) | 2020-03-11 |
| EP3487492A1 (en) | 2019-05-29 |
| US20190282541A1 (en) | 2019-09-19 |
| WO2018016563A1 (en) | 2018-01-25 |
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