|
US4970198A
(en)
|
1985-10-17 |
1990-11-13 |
American Cyanamid Company |
Antitumor antibiotics (LL-E33288 complex)
|
|
US5079233A
(en)
|
1987-01-30 |
1992-01-07 |
American Cyanamid Company |
N-acyl derivatives of the LL-E33288 antitumor antibiotics, composition and methods for using the same
|
|
US4975278A
(en)
|
1988-02-26 |
1990-12-04 |
Bristol-Myers Company |
Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells
|
|
US5606040A
(en)
|
1987-10-30 |
1997-02-25 |
American Cyanamid Company |
Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5225538A
(en)
|
1989-02-23 |
1993-07-06 |
Genentech, Inc. |
Lymphocyte homing receptor/immunoglobulin fusion proteins
|
|
US20030206899A1
(en)
|
1991-03-29 |
2003-11-06 |
Genentech, Inc. |
Vascular endothelial cell growth factor antagonists
|
|
US6582959B2
(en)
|
1991-03-29 |
2003-06-24 |
Genentech, Inc. |
Antibodies to vascular endothelial cell growth factor
|
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
ZA932522B
(en)
|
1992-04-10 |
1993-12-20 |
Res Dev Foundation |
Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens
|
|
AU687727B2
(en)
|
1992-10-28 |
1998-03-05 |
Genentech Inc. |
Vascular endothelial cell growth factor antagonists
|
|
DK0752248T3
(da)
|
1992-11-13 |
2000-11-13 |
Idec Pharma Corp |
Terapeutisk anvendelse af kimæriske og radioaktivt mærkede antistoffer mod humant B-lymfocytbegrænset differentieringsantig
|
|
US5773001A
(en)
|
1994-06-03 |
1998-06-30 |
American Cyanamid Company |
Conjugates of methyltrithio antitumor agents and intermediates for their synthesis
|
|
IL117645A
(en)
|
1995-03-30 |
2005-08-31 |
Genentech Inc |
Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration
|
|
US5994071A
(en)
|
1997-04-04 |
1999-11-30 |
Albany Medical College |
Assessment of prostate cancer
|
|
KR100816621B1
(ko)
|
1997-04-07 |
2008-03-24 |
제넨테크, 인크. |
항-vegf 항체
|
|
US20020032315A1
(en)
|
1997-08-06 |
2002-03-14 |
Manuel Baca |
Anti-vegf antibodies
|
|
US6884879B1
(en)
|
1997-04-07 |
2005-04-26 |
Genentech, Inc. |
Anti-VEGF antibodies
|
|
PT971959E
(pt)
|
1997-04-07 |
2006-05-31 |
Genentech Inc |
Anticorpos humanizados e metodos para formar anticorpos humanizados
|
|
US6858710B2
(en)
|
1998-12-17 |
2005-02-22 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6703020B1
(en)
|
1999-04-28 |
2004-03-09 |
Board Of Regents, The University Of Texas System |
Antibody conjugate methods for selectively inhibiting VEGF
|
|
CA2443617C
(en)
|
2001-04-17 |
2013-12-10 |
The Board Of Trustees Of The University Of Arkansas |
Repeat sequences of the ca125 gene and their use for diagnostic and therapeutic interventions
|
|
US20030078399A1
(en)
|
2001-05-11 |
2003-04-24 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acid sequence encoding ovarian antigen, CA125, and uses thereof
|
|
CA2491017A1
(en)
|
2002-07-03 |
2004-01-15 |
Immunogen, Inc. |
Antibodies to non-shed muc1 and muc16, and uses thereof
|
|
EP1391213A1
(en)
|
2002-08-21 |
2004-02-25 |
Boehringer Ingelheim International GmbH |
Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents
|
|
WO2004045553A2
(en)
|
2002-11-15 |
2004-06-03 |
The Board Of Trustees Of The University Of Arkansas |
Ca125 gene and its use for diagnostic and therapeutic interventions
|
|
UA101945C2
(uk)
|
2003-05-30 |
2013-05-27 |
Дженентек, Инк. |
Лікування злоякісного новоутворення за допомогою бевацизумабу
|
|
US20050106667A1
(en)
|
2003-08-01 |
2005-05-19 |
Genentech, Inc |
Binding polypeptides with restricted diversity sequences
|
|
WO2005044853A2
(en)
|
2003-11-01 |
2005-05-19 |
Genentech, Inc. |
Anti-vegf antibodies
|
|
NZ579482A
(en)
|
2004-06-01 |
2011-02-25 |
Genentech Inc |
Antibody drug conjugates and methods
|
|
US20060009360A1
(en)
|
2004-06-25 |
2006-01-12 |
Robert Pifer |
New adjuvant composition
|
|
DK1791565T3
(en)
|
2004-09-23 |
2016-08-01 |
Genentech Inc |
Cysteingensplejsede antibodies and conjugates
|
|
WO2006089125A2
(en)
*
|
2005-02-16 |
2006-08-24 |
Dana-Farber Cancer Institute |
Methods of detecting ovarian cancer
|
|
PL2135881T3
(pl)
|
2005-06-20 |
2012-02-29 |
Genentech Inc |
Przeciwciała wiążące się z antygenem TAT10772 związanym z nowotworem, do diagnozowania i leczenia nowotworu
|
|
JP5164855B2
(ja)
|
2006-01-04 |
2013-03-21 |
フジレビオ アメリカ、インク. |
子宮内膜または子宮癌を評価するためのhe4及びそのほかの生化学的マーカーの使用
|
|
MX2008009592A
(es)
*
|
2006-01-27 |
2008-09-08 |
Tripath Imaging Inc |
Metodos y composiciones para identificar pacientes con una probabilidad incrementada de tener cancer de ovario.
|
|
US7521441B2
(en)
|
2006-05-22 |
2009-04-21 |
Bristol-Myers Squibb Company |
Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors
|
|
CL2008001334A1
(es)
*
|
2007-05-08 |
2008-09-22 |
Genentech Inc |
Anticuerpo anti-muc16 disenado con cisteina; conjugado que lo comprende; metodo de produccion; formulacion farmaceutica que lo comprende; y su uso para tratar el cancer.
|
|
AU2008364786B2
(en)
|
2008-12-05 |
2014-04-03 |
The Government Of The U.S.A., As Represented By The Secretary, Department Of Health & Human Services |
Blocking mesothelin peptide fragments
|
|
CA2799540A1
(en)
|
2010-06-08 |
2011-12-15 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
|
WO2012170513A2
(en)
|
2011-06-06 |
2012-12-13 |
Women & Infants' Hospital Of Rhode Island |
He4 based therapy for malignant disease
|
|
SG190466A1
(en)
|
2011-11-18 |
2013-06-28 |
Agency Science Tech & Res |
Methods for diagnosis and/or prognosis of ovarian cancer
|
|
US9127081B2
(en)
|
2012-05-10 |
2015-09-08 |
Washington University |
Tumor targeted TNF-related apoptosis inducing ligand fusion polypeptide and nucleic acids encoding the same
|
|
RU2689760C2
(ru)
|
2012-05-31 |
2019-05-30 |
Дженентек, Инк. |
Способы лечения рака с применением антагонистов аксиального связывания pd-1 и vegf антагонистов
|
|
EP2971044B1
(en)
|
2013-03-13 |
2018-05-09 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating cancer
|
|
CN103954761B
(zh)
*
|
2014-04-22 |
2016-05-25 |
广州恒泰生物科技有限公司 |
用于卵巢癌早中期快速诊断试剂盒及其检测方法
|
|
CN108495625B
(zh)
*
|
2015-11-17 |
2021-07-27 |
柏林顿Hc研究集团有限公司 |
改善对氨基硫醇及其类似物的保护和递送的方法
|
|
JP2019524706A
(ja)
*
|
2016-07-08 |
2019-09-05 |
ジェネンテック, インコーポレイテッド |
Muc16陽性癌治療の応答性を評価するためのヒト精巣上体タンパク質4(he4)の使用
|