JP2014500862A5 - - Google Patents
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- Publication number
- JP2014500862A5 JP2014500862A5 JP2013536823A JP2013536823A JP2014500862A5 JP 2014500862 A5 JP2014500862 A5 JP 2014500862A5 JP 2013536823 A JP2013536823 A JP 2013536823A JP 2013536823 A JP2013536823 A JP 2013536823A JP 2014500862 A5 JP2014500862 A5 JP 2014500862A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- secad
- therapeutic agent
- cancer therapeutic
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40736710P | 2010-10-27 | 2010-10-27 | |
| US61/407,367 | 2010-10-27 | ||
| PCT/US2011/058076 WO2012058418A2 (en) | 2010-10-27 | 2011-10-27 | Compositions targeting the soluble extracellular domain of e-cadherin and related methods for cancer therapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014500862A JP2014500862A (ja) | 2014-01-16 |
| JP2014500862A5 true JP2014500862A5 (https=) | 2014-12-18 |
| JP6243737B2 JP6243737B2 (ja) | 2017-12-06 |
Family
ID=45994754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013536823A Active JP6243737B2 (ja) | 2010-10-27 | 2011-10-27 | Ｅ−カドヘリンの可溶性細胞外ドメインを標的とする組成物および癌治療のための関連方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20130287784A1 (https=) |
| EP (1) | EP2632489B1 (https=) |
| JP (1) | JP6243737B2 (https=) |
| KR (1) | KR20140075639A (https=) |
| CN (1) | CN103582494A (https=) |
| AU (1) | AU2011319777B2 (https=) |
| BR (1) | BR112013010535A2 (https=) |
| CA (1) | CA2816358A1 (https=) |
| ES (1) | ES2784385T3 (https=) |
| MX (2) | MX357167B (https=) |
| RU (1) | RU2013123792A (https=) |
| SG (3) | SG10201604467PA (https=) |
| WO (1) | WO2012058418A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9534058B2 (en) | 2012-02-08 | 2017-01-03 | Abbvie Stemcentrx Llc | Anti-CD324 monoclonal antibodies and uses thereof |
| EP2844270A4 (en) * | 2012-03-15 | 2016-01-27 | Univ New York State Res Found | COMBINATION THERAPIES WITH INHIBITORS OF THE EXTRACELLULAR DOMAIN OF E-CADHERINE |
| US9411750B2 (en) | 2012-07-30 | 2016-08-09 | International Business Machines Corporation | Efficient calibration of a low power parallel data communications channel |
| US9474034B1 (en) | 2015-11-30 | 2016-10-18 | International Business Machines Corporation | Power reduction in a parallel data communications interface using clock resynchronization |
| US10492104B2 (en) * | 2016-03-10 | 2019-11-26 | Cable Television Laboratories, Inc. | Latency reduction in wireless service |
| CN109076413B (zh) | 2016-03-10 | 2021-09-28 | 有线电视实验室公司 | 用于等待时间减少的系统和方法 |
| US10321351B2 (en) | 2017-03-02 | 2019-06-11 | Cable Television Laboratories, Inc. | System and method for grant assignment |
| US10738127B2 (en) | 2016-06-10 | 2020-08-11 | Veritas Biotecnologia Ltda | Monoclonal antibodies prevent cell surface protein shedding and block tumor growth |
| US10420085B2 (en) | 2016-10-07 | 2019-09-17 | Cable Television Laboratories, Inc. | System and method for grant assignment |
| US12225536B2 (en) | 2016-10-07 | 2025-02-11 | Cable Television Laboratories, Inc. | System and method for grant assignment |
| US10825479B2 (en) | 2018-05-11 | 2020-11-03 | Axon Enterprise, Inc. | Systems and methods for cross-redaction |
| US20240317880A1 (en) * | 2020-01-10 | 2024-09-26 | Kling Biotherapeutics B.V. | Epithelial Cadherin-Specific Antibodies |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4196265A (en) | 1977-06-15 | 1980-04-01 | The Wistar Institute | Method of producing antibodies |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4675187A (en) | 1983-05-16 | 1987-06-23 | Bristol-Myers Company | BBM-1675, a new antibiotic complex |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| KR940009084B1 (ko) | 1988-05-18 | 1994-09-29 | 체크 포인트 시스템스, 인코오퍼레이티드 | 자기 및 공명회로 검출용 안테나 시스템 |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| AU4128089A (en) | 1988-09-15 | 1990-03-22 | Rorer International (Overseas) Inc. | Monoclonal antibodies specific to human epidermal growth factor receptor and therapeutic methods employing same |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US6075181A (en) | 1990-01-12 | 2000-06-13 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| EP1690934A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| ATE300615T1 (de) | 1990-08-29 | 2005-08-15 | Genpharm Int | Transgene mäuse fähig zur produktion heterologer antikörper |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5698426A (en) | 1990-09-28 | 1997-12-16 | Ixsys, Incorporated | Surface expression libraries of heteromeric receptors |
| DK0580737T3 (da) | 1991-04-10 | 2004-11-01 | Scripps Research Inst | Heterodimere receptorbiblioteker ved anvendelse af phagemider |
| AU665025B2 (en) | 1991-09-23 | 1995-12-14 | Cambridge Antibody Technology Limited | Production of chimeric antibodies - a combinatorial approach |
| DE69232137T2 (de) | 1991-11-25 | 2002-05-29 | Enzon Inc | Multivalente antigen-bindende proteine |
| US5667988A (en) | 1992-01-27 | 1997-09-16 | The Scripps Research Institute | Methods for producing antibody libraries using universal or randomized immunoglobulin light chains |
| EP1306095A3 (en) | 1992-03-05 | 2003-06-25 | Board Of Regents, The University Of Texas System | Methods and compositions for targeting the vasculature of solid tumors |
| US6004555A (en) | 1992-03-05 | 1999-12-21 | Board Of Regents, The University Of Texas System | Methods for the specific coagulation of vasculature |
| US6093399A (en) | 1992-03-05 | 2000-07-25 | Board Of Regents, The University Of Texas System | Methods and compositions for the specific coagulation of vasculature |
| US5877289A (en) | 1992-03-05 | 1999-03-02 | The Scripps Research Institute | Tissue factor compositions and ligands for the specific coagulation of vasculature |
| US5965132A (en) | 1992-03-05 | 1999-10-12 | Board Of Regents, The University Of Texas System | Methods and compositions for targeting the vasculature of solid tumors |
| AU5669494A (en) * | 1992-11-17 | 1994-06-08 | Yale University | Human homolog of the e-cadherin gene and methods based thereon |
| DE614989T1 (de) | 1993-02-17 | 1995-09-28 | Morphosys Proteinoptimierung | Verfahren für in vivo Selektion von Ligandenbindende Proteine. |
| US6091001A (en) | 1995-03-29 | 2000-07-18 | Abgenix, Inc. | Production of antibodies using Cre-mediated site-specific recombination |
| US5702892A (en) | 1995-05-09 | 1997-12-30 | The United States Of America As Represented By The Department Of Health And Human Services | Phage-display of immunoglobulin heavy chain libraries |
| US6723320B2 (en) * | 1996-07-24 | 2004-04-20 | Gsf Forschungszentrum Fur Umwelt Und Geshundheit Gmbh | Mutations of E cadherin as a basis for the diagnosis and therapy of human malignant tumors |
| US6015557A (en) | 1999-02-24 | 2000-01-18 | Tobinick; Edward L. | Tumor necrosis factor antagonists for the treatment of neurological disorders |
| AU2002226075A1 (en) * | 2000-10-23 | 2002-05-06 | University Of Kansas | Cadherin peptides for drug delivery and inhibition of tumor metastasis/invasion |
| CA2441626A1 (en) | 2001-03-28 | 2002-10-17 | Children's Medical Center Corporation | Fusion protein construct and method for inducing hiv-specific serum igg and secretory iga antibodies in-vivo |
| US7074175B2 (en) | 2001-07-25 | 2006-07-11 | Erik Schroeder Handy | Thermotherapy via targeted delivery of nanoscale magnetic particles |
| US6997863B2 (en) | 2001-07-25 | 2006-02-14 | Triton Biosystems, Inc. | Thermotherapy via targeted delivery of nanoscale magnetic particles |
| US20060239970A1 (en) | 2003-01-23 | 2006-10-26 | Federoff Howard J | Herpesvirus amplicon particles |
| US8455249B2 (en) * | 2009-05-01 | 2013-06-04 | The University Of Tokyo | Highly effective anti-cadherin antibody for induction of antibody-dependent cellular cytotoxicity in vivo |
-
2011
- 2011-10-27 EP EP11837082.4A patent/EP2632489B1/en active Active
- 2011-10-27 ES ES11837082T patent/ES2784385T3/es active Active
- 2011-10-27 US US13/882,078 patent/US20130287784A1/en not_active Abandoned
- 2011-10-27 SG SG10201604467PA patent/SG10201604467PA/en unknown
- 2011-10-27 CA CA2816358A patent/CA2816358A1/en not_active Abandoned
- 2011-10-27 CN CN201180063111.1A patent/CN103582494A/zh active Pending
- 2011-10-27 WO PCT/US2011/058076 patent/WO2012058418A2/en not_active Ceased
- 2011-10-27 AU AU2011319777A patent/AU2011319777B2/en active Active
- 2011-10-27 KR KR1020137013383A patent/KR20140075639A/ko not_active Ceased
- 2011-10-27 MX MX2013004790A patent/MX357167B/es active IP Right Grant
- 2011-10-27 BR BR112013010535A patent/BR112013010535A2/pt not_active Application Discontinuation
- 2011-10-27 JP JP2013536823A patent/JP6243737B2/ja active Active
- 2011-10-27 RU RU2013123792/15A patent/RU2013123792A/ru not_active Application Discontinuation
- 2011-10-27 SG SG2013032875A patent/SG189547A1/en unknown
- 2011-10-27 SG SG10202100921YA patent/SG10202100921YA/en unknown
-
2013
- 2013-04-26 MX MX2018007983A patent/MX2018007983A/es unknown
-
2015
- 2015-03-30 US US14/673,539 patent/US20160046701A1/en not_active Abandoned
-
2019
- 2019-01-24 US US16/256,800 patent/US20190352380A1/en not_active Abandoned
-
2021
- 2021-08-19 US US17/406,611 patent/US20210380671A1/en not_active Abandoned
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