JP2019521178A5 - - Google Patents
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- Publication number
- JP2019521178A5 JP2019521178A5 JP2019515760A JP2019515760A JP2019521178A5 JP 2019521178 A5 JP2019521178 A5 JP 2019521178A5 JP 2019515760 A JP2019515760 A JP 2019515760A JP 2019515760 A JP2019515760 A JP 2019515760A JP 2019521178 A5 JP2019521178 A5 JP 2019521178A5
- Authority
- JP
- Japan
- Prior art keywords
- amoxicillin
- formulation
- powder
- cineole
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 28
- 238000009472 formulation Methods 0.000 claims 26
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 claims 23
- 229960003022 amoxicillin Drugs 0.000 claims 23
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 claims 23
- 239000000843 powder Substances 0.000 claims 17
- WEEGYLXZBRQIMU-UHFFFAOYSA-N Eucalyptol Chemical compound C1CC2CCC1(C)OC2(C)C WEEGYLXZBRQIMU-UHFFFAOYSA-N 0.000 claims 16
- 229960005233 cineole Drugs 0.000 claims 16
- 239000003781 beta lactamase inhibitor Substances 0.000 claims 13
- 229940126813 beta-lactamase inhibitor Drugs 0.000 claims 13
- 239000008194 pharmaceutical composition Substances 0.000 claims 13
- 229940126085 β‑Lactamase Inhibitor Drugs 0.000 claims 13
- RFFOTVCVTJUTAD-UHFFFAOYSA-N cineole Natural products C1CC2(C)CCC1(C(C)C)O2 RFFOTVCVTJUTAD-UHFFFAOYSA-N 0.000 claims 12
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 claims 9
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 claims 9
- 229960003324 clavulanic acid Drugs 0.000 claims 9
- 208000035143 Bacterial infection Diseases 0.000 claims 8
- 208000022362 bacterial infectious disease Diseases 0.000 claims 8
- 239000003921 oil Substances 0.000 claims 8
- 235000019198 oils Nutrition 0.000 claims 8
- 241000894006 Bacteria Species 0.000 claims 4
- 239000003242 anti bacterial agent Substances 0.000 claims 4
- 229940088710 antibiotic agent Drugs 0.000 claims 4
- 229930007050 cineol Natural products 0.000 claims 4
- 201000003146 cystitis Diseases 0.000 claims 4
- 208000015181 infectious disease Diseases 0.000 claims 4
- 206010006451 bronchitis Diseases 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 150000003952 β-lactams Chemical class 0.000 claims 3
- 208000027775 Bronchopulmonary disease Diseases 0.000 claims 2
- 206010007882 Cellulitis Diseases 0.000 claims 2
- 239000003125 aqueous solvent Substances 0.000 claims 2
- 230000001580 bacterial effect Effects 0.000 claims 2
- 239000007884 disintegrant Substances 0.000 claims 2
- 239000000796 flavoring agent Substances 0.000 claims 2
- 235000019634 flavors Nutrition 0.000 claims 2
- 235000003599 food sweetener Nutrition 0.000 claims 2
- 239000000314 lubricant Substances 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 239000003765 sweetening agent Substances 0.000 claims 2
- 206010001076 Acute sinusitis Diseases 0.000 claims 1
- 206010002515 Animal bite Diseases 0.000 claims 1
- 206010006458 Bronchitis chronic Diseases 0.000 claims 1
- 239000001692 EU approved anti-caking agent Substances 0.000 claims 1
- 208000019693 Lung disease Diseases 0.000 claims 1
- 206010048685 Oral infection Diseases 0.000 claims 1
- 206010031252 Osteomyelitis Diseases 0.000 claims 1
- 208000005141 Otitis Diseases 0.000 claims 1
- 206010037596 Pyelonephritis Diseases 0.000 claims 1
- 208000007313 Reproductive Tract Infections Diseases 0.000 claims 1
- 206010000269 abscess Diseases 0.000 claims 1
- 201000005661 acute cystitis Diseases 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 201000008837 acute maxillary sinusitis Diseases 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 210000000621 bronchi Anatomy 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 208000007451 chronic bronchitis Diseases 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000019258 ear infection Diseases 0.000 claims 1
- 230000002458 infectious effect Effects 0.000 claims 1
- 208000022760 infectious otitis media Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 238000004806 packaging method and process Methods 0.000 claims 1
- 201000001245 periodontitis Diseases 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 230000000306 recurrent effect Effects 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 201000009890 sinusitis Diseases 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 235000015112 vegetable and seed oil Nutrition 0.000 claims 1
- 239000008158 vegetable oil Substances 0.000 claims 1
- 238000009736 wetting Methods 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MA39084 | 2016-06-02 | ||
| FR1655018A FR3052065B1 (fr) | 2016-06-02 | 2016-06-02 | Combinaison de cineol et d'amoxicilline pour une utilisation dans le traitement d'une infection bacterienne |
| FR1655017A FR3052066B1 (fr) | 2016-06-02 | 2016-06-02 | Formulation pharmaceutique de cineol et d'amoxicilline |
| MA39085A MA39085B1 (fr) | 2016-06-02 | 2016-06-02 | Combinaison de cineol et d'amoxicilline pour une utilisation dans le traitement d'une infection bacterienne |
| FR1655018 | 2016-06-02 | ||
| MA39084A MA39084A1 (fr) | 2016-06-02 | 2016-06-02 | Formulation pharmaceutique de cineol et d'amoxicilline |
| FR1655017 | 2016-06-02 | ||
| MA39085 | 2016-06-02 | ||
| PCT/MA2017/000014 WO2017209588A2 (fr) | 2016-06-02 | 2017-06-02 | Formulation pharmaceutique de cinéol et d'amoxicilline |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019521178A JP2019521178A (ja) | 2019-07-25 |
| JP2019521178A5 true JP2019521178A5 (https=) | 2020-06-25 |
| JP7033586B2 JP7033586B2 (ja) | 2022-03-10 |
Family
ID=59399462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019515760A Active JP7033586B2 (ja) | 2016-06-02 | 2017-06-02 | シネオールとアモキシシリンとを含む医薬製剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11872216B2 (https=) |
| EP (1) | EP3463479B1 (https=) |
| JP (1) | JP7033586B2 (https=) |
| CN (1) | CN109562182A (https=) |
| CA (1) | CA3026323A1 (https=) |
| MA (1) | MA44286A (https=) |
| SA (1) | SA518400554B1 (https=) |
| WO (1) | WO2017209588A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017209588A2 (fr) * | 2016-06-02 | 2017-12-07 | Advanced Scientific Developements | Formulation pharmaceutique de cinéol et d'amoxicilline |
| US12460153B2 (en) | 2019-12-04 | 2025-11-04 | Pranarom International S.A. | Method for transforming an essential oil |
| DE202021106639U1 (de) | 2021-10-08 | 2023-01-10 | Maria Clementine Martin Klosterfrau Vertriebsgesellschaft mit beschränkter Haftung | Neue Therapiekonzepte für die Behandlung von Otitis |
| CN118267361B (zh) * | 2024-05-31 | 2024-08-23 | 潍坊格润药业有限公司 | 一种兽用复方阿莫西林可溶性粉 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007534620A (ja) * | 2003-07-17 | 2007-11-29 | ザ トラスティース オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク | 第４級アンモニウム化合物と精油および／またはその構成要素の相乗的組合せを含む抗菌組成物 |
| WO2006120495A1 (fr) | 2005-05-13 | 2006-11-16 | Advanced Scientific Developements | Composition pharmaceutique comprenant un antiviral, an antitumoral ou un antiparasitaire, et un actif choisi parmi le carveol, le thymol, l’eugenol, le borneol et le carvacrol |
| WO2006120494A1 (fr) | 2005-05-13 | 2006-11-16 | Advanced Scientific Developements | Combinaison pharmaceutique comprenant un antibacterien et une substance active choisie parmi le carveol, le thymol, l’eugenol, le borneol et les carvacrol |
| WO2006120496A1 (fr) | 2005-05-13 | 2006-11-16 | Advanced Scientific Developements | Combinaison pharmaceutique comprenant un agent antifongique et un actif choisi parmi le carveol, l’ eugenol, le thymol, le borneol, et le carvacrol |
| US20080139526A1 (en) * | 2006-12-06 | 2008-06-12 | Donald Treacy | Modified release dosage forms of amoxicillin |
| DE102006007830A1 (de) * | 2006-02-17 | 2007-08-30 | Grünenthal GmbH | Lagerstabile orale Darreichungsform von Amoxicillin und Clavulansäure |
| JP2011516527A (ja) * | 2008-04-09 | 2011-05-26 | レツク・フアーマシユーテイカルズ・デー・デー | 医薬品有効成分の造粒 |
| FR2937549B1 (fr) | 2008-10-29 | 2011-04-01 | Centre Nat Rech Scient | Nanoparticules de derives beta-lactamine |
| WO2012076717A1 (en) * | 2010-12-09 | 2012-06-14 | Societe De Developpement Scientifique - Sds | Pharmaceutical composition comprising trans-cinnamaldehyde and its use in the treatment of infections |
| WO2012114201A1 (en) * | 2011-02-25 | 2012-08-30 | Aroma Technologies | Nanocapsulation of essential oils for preventing or curing infectious diseases alone or with an antibiotic |
| US8852648B2 (en) | 2012-11-06 | 2014-10-07 | Rochal Industries, Llp | Delivery of biologically-active agents using volatile, hydrophobic solvents |
| MA35295B1 (fr) | 2012-12-31 | 2014-08-01 | Advanced Scient Developments | Complexe moleculaire detoxifiant et antimicrobien |
| FR3025719A1 (fr) * | 2014-09-15 | 2016-03-18 | Septeos | Antimicrobiens potentialises |
| WO2017209588A2 (fr) * | 2016-06-02 | 2017-12-07 | Advanced Scientific Developements | Formulation pharmaceutique de cinéol et d'amoxicilline |
-
2017
- 2017-06-02 WO PCT/MA2017/000014 patent/WO2017209588A2/fr not_active Ceased
- 2017-06-02 MA MA044286A patent/MA44286A/fr unknown
- 2017-06-02 CN CN201780041549.7A patent/CN109562182A/zh active Pending
- 2017-06-02 US US16/306,262 patent/US11872216B2/en active Active
- 2017-06-02 CA CA3026323A patent/CA3026323A1/fr active Pending
- 2017-06-02 EP EP17743405.7A patent/EP3463479B1/fr active Active
- 2017-06-02 JP JP2019515760A patent/JP7033586B2/ja active Active
-
2018
- 2018-11-29 SA SA518400554A patent/SA518400554B1/ar unknown
-
2024
- 2024-01-10 US US18/408,636 patent/US20240148702A1/en active Pending
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