JP2019521113A - 生体システム用の組成物並びに組成物を調製及び使用する方法 - Google Patents
生体システム用の組成物並びに組成物を調製及び使用する方法 Download PDFInfo
- Publication number
- JP2019521113A JP2019521113A JP2018564394A JP2018564394A JP2019521113A JP 2019521113 A JP2019521113 A JP 2019521113A JP 2018564394 A JP2018564394 A JP 2018564394A JP 2018564394 A JP2018564394 A JP 2018564394A JP 2019521113 A JP2019521113 A JP 2019521113A
- Authority
- JP
- Japan
- Prior art keywords
- composition
- volume
- cells
- interleukin
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/34—Sugars
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662349633P | 2016-06-13 | 2016-06-13 | |
| US62/349,633 | 2016-06-13 | ||
| US15/619,467 | 2017-06-10 | ||
| US15/619,467 US10426796B2 (en) | 2016-06-13 | 2017-06-10 | Compositions for biological systems and methods for preparing and using the same |
| PCT/US2017/037055 WO2017218427A1 (en) | 2016-06-13 | 2017-06-12 | Compositions for biological systems and methods for preparing and using the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019521113A true JP2019521113A (ja) | 2019-07-25 |
| JP2019521113A5 JP2019521113A5 (https=) | 2020-07-30 |
Family
ID=60572084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018564394A Pending JP2019521113A (ja) | 2016-06-13 | 2017-06-12 | 生体システム用の組成物並びに組成物を調製及び使用する方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US10426796B2 (https=) |
| EP (1) | EP3468570A4 (https=) |
| JP (1) | JP2019521113A (https=) |
| KR (1) | KR20190018677A (https=) |
| CN (1) | CN109562130A (https=) |
| AU (1) | AU2017284186A1 (https=) |
| CA (1) | CA3026575A1 (https=) |
| MX (1) | MX2018015388A (https=) |
| WO (1) | WO2017218427A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10456423B2 (en) * | 2016-06-13 | 2019-10-29 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
| CN108823160B (zh) * | 2018-07-25 | 2020-08-21 | 广州赛莱拉干细胞科技股份有限公司 | 一种脐带间充质干细胞原代培养基及其原代培养方法 |
| CN109628406B (zh) * | 2019-01-03 | 2021-02-26 | 北京贝来生物科技有限公司 | 一种治疗自身免疫疾病的间充质干细胞及其制备方法和应用 |
| CN114452285B (zh) * | 2022-02-17 | 2022-11-25 | 中国中医科学院中药研究所 | 一种il-17a拮抗剂在治疗糖尿病溃疡中的用途 |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11322618A (ja) * | 1998-05-13 | 1999-11-24 | Asahi Medical Co Ltd | 有核細胞分離回収方法及び有核細胞含有液 |
| JP2000038348A (ja) * | 1998-05-21 | 2000-02-08 | Nissho Corp | アルブミン含有腹膜透析液 |
| WO2009057537A1 (ja) * | 2007-11-02 | 2009-05-07 | Jcr Pharmaceuticals Co., Ltd. | ヒト間葉系幹細胞含有医薬組成物 |
| JP2010116400A (ja) * | 2001-11-29 | 2010-05-27 | Stemcyte Inc | Hiv感染に対する幹細胞スクリーニングおよび移植治療 |
| WO2016068266A1 (ja) * | 2014-10-31 | 2016-05-06 | 国立大学法人京都大学 | 生分解性ポリマーを用いた3次元培養方法、及び細胞移植を可能にする培養基材 |
| WO2016076428A1 (ja) * | 2014-11-14 | 2016-05-19 | 日本赤十字社 | 臍帯血および末梢血の凍結保存方法および凍結保存用溶液 |
| WO2016081518A2 (en) * | 2014-11-17 | 2016-05-26 | Adicet Bio, Inc. | Engineered gamma delta t-cells |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5525519A (en) | 1992-01-07 | 1996-06-11 | Middlesex Sciences, Inc. | Method for isolating biomolecules from a biological sample with linear polymers |
| ES2157260T3 (es) | 1993-06-04 | 2001-08-16 | Biotime Inc | Solucion semejante a plasma. |
| US5543316A (en) | 1994-04-20 | 1996-08-06 | Diacrin, Inc. | Injectable culture medium for maintaining viability of myoblast cells |
| US6153582A (en) | 1998-11-05 | 2000-11-28 | Bausch & Lomb Surgical, Inc. | Defined serumfree medical solution for ophthalmology |
| US6899889B1 (en) | 1998-11-06 | 2005-05-31 | Neomend, Inc. | Biocompatible material composition adaptable to diverse therapeutic indications |
| US7020845B1 (en) * | 1999-11-15 | 2006-03-28 | Gottfurcht Elliot A | Navigating internet content on a television using a simplified interface and a remote control |
| US7274368B1 (en) * | 2000-07-31 | 2007-09-25 | Silicon Graphics, Inc. | System method and computer program product for remote graphics processing |
| CN100553636C (zh) * | 2000-08-04 | 2009-10-28 | Dmi生物科学公司 | 二酮基哌嗪和包含它们的组合物的使用方法 |
| DK1349918T3 (da) | 2000-12-06 | 2014-11-10 | Anthrogenesis Corp | Fremgangsmåde til indsamling af stamceller fra moderkagen |
| IL158171A0 (en) | 2001-04-10 | 2004-03-28 | Bioergonomics Inc | Compositions and methods for cell separation |
| US7771716B2 (en) * | 2001-12-07 | 2010-08-10 | Cytori Therapeutics, Inc. | Methods of using regenerative cells in the treatment of musculoskeletal disorders |
| US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
| US20110280838A1 (en) | 2007-12-27 | 2011-11-17 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of intervertebral disc degeneration using human umbilical cord tissue-derived cells |
| CA2581424A1 (en) | 2004-03-09 | 2005-09-22 | Gang Xu | Methods for generating insulin-producing cells |
| US7622108B2 (en) * | 2004-04-23 | 2009-11-24 | Bioe, Inc. | Multi-lineage progenitor cells |
| US7670596B2 (en) | 2004-04-23 | 2010-03-02 | Bioe, Inc. | Multi-lineage progenitor cells |
| JP2007536936A (ja) | 2004-05-14 | 2007-12-20 | ベクトン・ディキンソン・アンド・カンパニー | 幹細胞集団および使用方法 |
| WO2007019678A1 (en) * | 2005-08-12 | 2007-02-22 | University Health Network | Methods and devices for lymphatic targeting |
| SE529040C2 (sv) * | 2006-01-18 | 2007-04-17 | Bows Pharmaceuticals Ag | Förfarande för framställning av en dextranmatris för kontrollerad frisättning av insulin |
| CA2646491A1 (en) | 2006-04-17 | 2007-10-25 | Bioe, Inc. | Differentiation of multi-lineage progenitor cells to respiratory epithelial cells |
| US9598673B2 (en) * | 2006-05-19 | 2017-03-21 | Creative Medical Health | Treatment of disc degenerative disease |
| WO2007134461A1 (en) * | 2006-05-24 | 2007-11-29 | Titan Medical Inc. | Snaking robotic arm with movable shapers |
| WO2008034803A1 (en) | 2006-09-18 | 2008-03-27 | Medizinische Universität Graz | Plasma-free platelet lysate for use as a supplement in cell cultures and for the preparation of cell therapeutics |
| US20090229463A1 (en) | 2008-02-15 | 2009-09-17 | Coalstar Industries, Inc. | Apparatus and processes for production of coke and activated carbon from coal products |
| HU0800134D0 (en) * | 2008-02-26 | 2008-04-28 | Semmelweis Egyetem | Procedure for producing mineralized bone composition |
| CA2724839A1 (en) | 2008-05-21 | 2009-11-26 | Bioe Llc | Differentiation of multi-lineage progenitor cells to pancreatic cells |
| US20120093782A1 (en) * | 2009-05-13 | 2012-04-19 | Grove Robert I | Enhanced Hematopoietic Stem Cell Engraftment |
| US9168442B2 (en) * | 2009-09-21 | 2015-10-27 | Thomas M. Covino | Gaming surface and game styled after american football |
| EP2483392B1 (en) | 2009-09-23 | 2015-11-11 | Davinci Biosciences LLC | Umbilical cord lining stem cells and methods and material for isolating and culturing same |
| CA2802203A1 (en) * | 2010-06-10 | 2011-12-15 | Aastrom Biosciences, Inc. | Compositions and methods of treating no-option critical limb ischemia (cli) |
| US20130323712A1 (en) | 2010-11-25 | 2013-12-05 | Kaneka Corporation | Method and material for separating leukocytes or mononuclear cells |
| CA2774383A1 (en) | 2011-06-22 | 2012-12-22 | Shaf Keshavjee | Repaired organ and method for making the same |
| WO2013134464A1 (en) * | 2012-03-07 | 2013-09-12 | Children's Medical Center Corporation | Tissue constructs and uses thereof |
| SG11201407768QA (en) | 2012-04-24 | 2015-01-29 | Brigham & Womens Hospital | Generating pluripotent cells de novo |
| CN104094557A (zh) * | 2012-05-30 | 2014-10-08 | 株式会社东芝 | 铁路车辆用传送装置、铁路车辆、控制方法以及控制程序 |
| US9283084B1 (en) | 2012-07-24 | 2016-03-15 | Thomas E. O'Hara | Spinal fusion cage and vertebral body clamp |
| CN102920734A (zh) * | 2012-11-14 | 2013-02-13 | 青岛奥克生物开发有限公司 | 一种间充质干细胞注射液及其制备方法和在制备治疗溃疡性结肠炎药物中的应用 |
| AU2013364097A1 (en) * | 2012-12-18 | 2015-07-02 | Robert Chow | Blood cell preparations and related methods (GEN 8) |
| SG11201505965TA (en) | 2013-01-31 | 2015-09-29 | Ajinomoto Kk | Culture method for stable undifferentiated proliferation of pluripotent stem cells |
| SG11201505715RA (en) * | 2013-02-01 | 2015-08-28 | Ampio Pharmaceuticals Inc | Methods for producing diketopiperazines and compositions containing diketopiperazines |
| US9241959B2 (en) | 2013-03-13 | 2016-01-26 | Mingqi TANG | Kits and methods for processing stem cells from bone marrow or umbilical cord blood |
| SG11201507515YA (en) | 2013-03-15 | 2015-10-29 | Marcus Kare Torleif Larsson | Cells, methods and apparatuses for umbilical cord blood collection and isolation of cells |
| US9943545B2 (en) | 2013-03-15 | 2018-04-17 | Fate Therapeutics, Inc. | Stem cell culture media and methods of enhancing cell survival |
| BR112015020469A2 (pt) * | 2013-03-15 | 2020-01-28 | Ampio Pharmaceuticals Inc | Usos de da-dkp, composição e método para fornecimento de células-tronco a umindivíduo |
| KR20220044384A (ko) | 2013-10-03 | 2022-04-07 | 안트로제네시스 코포레이션 | 사람 태반으로부터의 세포 및 조혈 세포를 사용한 치료 |
| US9238984B2 (en) * | 2014-02-03 | 2016-01-19 | Caterpillar, Inc. | Exhaust emission prediction system and method |
| TWI548748B (zh) | 2015-04-16 | 2016-09-11 | 台灣尖端先進生技醫藥股份有限公司 | 造血幹/先驅細胞之體外放大培養方法及其立即可使用之組成物 |
| KR20180021736A (ko) | 2015-06-15 | 2018-03-05 | 바이탈 쎄러피스, 인코포레이티드 | 세포의 항아폽토시스, 생존, 또는 증식을 유도하기 위한 조성물 및 방법 |
-
2017
- 2017-06-10 US US15/619,467 patent/US10426796B2/en not_active Expired - Fee Related
- 2017-06-12 AU AU2017284186A patent/AU2017284186A1/en not_active Abandoned
- 2017-06-12 CA CA3026575A patent/CA3026575A1/en active Pending
- 2017-06-12 WO PCT/US2017/037055 patent/WO2017218427A1/en not_active Ceased
- 2017-06-12 CN CN201780049575.4A patent/CN109562130A/zh active Pending
- 2017-06-12 JP JP2018564394A patent/JP2019521113A/ja active Pending
- 2017-06-12 EP EP17813877.2A patent/EP3468570A4/en not_active Withdrawn
- 2017-06-12 KR KR1020197000781A patent/KR20190018677A/ko not_active Abandoned
- 2017-06-12 MX MX2018015388A patent/MX2018015388A/es unknown
- 2017-08-11 US US15/675,542 patent/US10213463B2/en not_active Expired - Fee Related
-
2018
- 2018-05-24 US US15/988,855 patent/US10363271B2/en not_active Expired - Fee Related
-
2019
- 2019-07-09 US US16/506,528 patent/US20190328789A1/en not_active Abandoned
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11322618A (ja) * | 1998-05-13 | 1999-11-24 | Asahi Medical Co Ltd | 有核細胞分離回収方法及び有核細胞含有液 |
| JP2000038348A (ja) * | 1998-05-21 | 2000-02-08 | Nissho Corp | アルブミン含有腹膜透析液 |
| JP2010116400A (ja) * | 2001-11-29 | 2010-05-27 | Stemcyte Inc | Hiv感染に対する幹細胞スクリーニングおよび移植治療 |
| WO2009057537A1 (ja) * | 2007-11-02 | 2009-05-07 | Jcr Pharmaceuticals Co., Ltd. | ヒト間葉系幹細胞含有医薬組成物 |
| WO2016068266A1 (ja) * | 2014-10-31 | 2016-05-06 | 国立大学法人京都大学 | 生分解性ポリマーを用いた3次元培養方法、及び細胞移植を可能にする培養基材 |
| WO2016076428A1 (ja) * | 2014-11-14 | 2016-05-19 | 日本赤十字社 | 臍帯血および末梢血の凍結保存方法および凍結保存用溶液 |
| WO2016081518A2 (en) * | 2014-11-17 | 2016-05-26 | Adicet Bio, Inc. | Engineered gamma delta t-cells |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20190018677A (ko) | 2019-02-25 |
| US10363271B2 (en) | 2019-07-30 |
| EP3468570A1 (en) | 2019-04-17 |
| AU2017284186A1 (en) | 2019-01-03 |
| CA3026575A1 (en) | 2017-12-21 |
| US20190328789A1 (en) | 2019-10-31 |
| US10213463B2 (en) | 2019-02-26 |
| EP3468570A4 (en) | 2020-01-01 |
| US20170354683A1 (en) | 2017-12-14 |
| MX2018015388A (es) | 2019-04-29 |
| US10426796B2 (en) | 2019-10-01 |
| US20170354684A1 (en) | 2017-12-14 |
| WO2017218427A1 (en) | 2017-12-21 |
| CN109562130A (zh) | 2019-04-02 |
| US20180264041A1 (en) | 2018-09-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Cassano et al. | Bone marrow concentrate and platelet-rich plasma differ in cell distribution and interleukin 1 receptor antagonist protein concentration | |
| Kraus et al. | Mesenchymal stem cells and bone regeneration | |
| Muschler et al. | Selective retention of bone marrow-derived cells to enhance spinal fusion. | |
| Muschler et al. | Spine fusion using cell matrix composites enriched in bone marrow-derived cells. | |
| Serra-Mestre et al. | Platelet-rich plasma mixed-fat grafting: a reasonable prosurvival strategy for fat grafts? | |
| Udehiya et al. | Comparison of autogenic and allogenic bone marrow derived mesenchymal stem cells for repair of segmental bone defects in rabbits | |
| Silva et al. | Cytokines and growth factors | |
| US20190328789A1 (en) | Compositions for biological systems and methods for preparing and using the same | |
| Yoon et al. | Synergistic action of IL-8 and bone marrow concentrate on cartilage regeneration through upregulation of chondrogenic transcription factors | |
| Betsch et al. | The role of erythropoietin and bone marrow concentrate in the treatment of osteochondral defects in mini-pigs | |
| US11369640B2 (en) | Compositions for biological systems and methods for preparing and using the same | |
| Seebach et al. | Cell-based therapy by autologous bone marrow-derived mononuclear cells for bone augmentation of plate-stabilized proximal humeral fractures: a multicentric, randomized, open phase IIa study | |
| Murray et al. | Biologics in orthopaedics: concepts and controversies | |
| Ruiz et al. | New formulations of platelet-rich plasma: the relevance of extraplatelet molecules | |
| Zhang et al. | Stromal cell-derived factor (SDF)-1α and platelet-rich plasma enhance bone regeneration and angiogenesis simultaneously in situ in rabbit calvaria | |
| Reinisch et al. | Autologous lipotransfer for bone defects secondary to osteomyelitis: A report of a novel method and systematic review of the literature | |
| Gu et al. | The impact of centrifugal force on isolation of bone marrow mononuclear cells using density gradient centrifugation | |
| Wang et al. | Construction of tissue‑engineered bone using a bioreactor and platelet‑rich plasma | |
| Li et al. | [Retracted] Comparison of the Effects of Repeated Applications of Platelet‐Rich Plasma versus Platelet‐Poor Plasma on Fat Graft Survival in Nude Mice | |
| Paul et al. | Effect of G‐CSF on the osteoinductive property of a BCP/blood clot composite | |
| Leung et al. | Osteochondral tissue engineering for osteoarthritis using infrapatellar fat-pad derived mesenchymal stem cells | |
| WO2018226435A1 (en) | Compositions for biological systems and methods for preparing and using the same | |
| Sun et al. | A crucial role of IL-17 in bone resorption during rejection of fresh bone xenotransplantation in rats | |
| EP3161479B1 (en) | Methods for assessing the efficacy of anti-inflammatory cytokine compositions | |
| Karli et al. | Biologic and Cellular Therapies in the Clinical Setting: Standardization and Collaboration |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20190913 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20200605 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20200605 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20200609 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20210518 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20210816 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20211118 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20220412 |