JP2019521098A5 - - Google Patents
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- Publication number
- JP2019521098A5 JP2019521098A5 JP2018562357A JP2018562357A JP2019521098A5 JP 2019521098 A5 JP2019521098 A5 JP 2019521098A5 JP 2018562357 A JP2018562357 A JP 2018562357A JP 2018562357 A JP2018562357 A JP 2018562357A JP 2019521098 A5 JP2019521098 A5 JP 2019521098A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- antigen
- binding fragment
- complementarity determining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022130091A JP2022159476A (ja) | 2016-06-10 | 2022-08-17 | 抗ｇｉｔｒ抗体およびその使用 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662348353P | 2016-06-10 | 2016-06-10 | |
| US62/348,353 | 2016-06-10 | ||
| US201662432023P | 2016-12-09 | 2016-12-09 | |
| US62/432,023 | 2016-12-09 | ||
| US201762500312P | 2017-05-02 | 2017-05-02 | |
| US62/500,312 | 2017-05-02 | ||
| PCT/US2017/036818 WO2017214548A1 (en) | 2016-06-10 | 2017-06-09 | Anti-gitr antibodies and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022130091A Division JP2022159476A (ja) | 2016-06-10 | 2022-08-17 | 抗ｇｉｔｒ抗体およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019521098A JP2019521098A (ja) | 2019-07-25 |
| JP2019521098A5 true JP2019521098A5 (enExample) | 2020-07-27 |
| JP7162535B2 JP7162535B2 (ja) | 2022-10-28 |
Family
ID=59078260
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018562357A Active JP7162535B2 (ja) | 2016-06-10 | 2017-06-09 | 抗ｇｉｔｒ抗体およびその使用 |
| JP2022130091A Pending JP2022159476A (ja) | 2016-06-10 | 2022-08-17 | 抗ｇｉｔｒ抗体およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022130091A Pending JP2022159476A (ja) | 2016-06-10 | 2022-08-17 | 抗ｇｉｔｒ抗体およびその使用 |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US10738126B2 (enExample) |
| EP (2) | EP4344748A3 (enExample) |
| JP (2) | JP7162535B2 (enExample) |
| KR (1) | KR102495601B1 (enExample) |
| CN (1) | CN109563170B (enExample) |
| AU (1) | AU2017278193B9 (enExample) |
| BR (1) | BR112018075434A2 (enExample) |
| CA (1) | CA3027121A1 (enExample) |
| CL (1) | CL2018003515A1 (enExample) |
| CO (1) | CO2018013298A2 (enExample) |
| IL (1) | IL263273B2 (enExample) |
| MA (1) | MA45233A (enExample) |
| MX (2) | MX2018015350A (enExample) |
| MY (1) | MY200162A (enExample) |
| PH (1) | PH12018502502A1 (enExample) |
| SG (1) | SG11201810525XA (enExample) |
| UA (1) | UA128687C2 (enExample) |
| WO (1) | WO2017214548A1 (enExample) |
| ZA (1) | ZA201807920B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR097306A1 (es) | 2013-08-20 | 2016-03-02 | Merck Sharp & Dohme | Modulación de la inmunidad tumoral |
| CA3027121A1 (en) | 2016-06-10 | 2017-12-14 | Regeneron Pharmaceuticals, Inc. | Anti-gitr antibodies and uses thereof |
| KR20230133934A (ko) | 2016-10-11 | 2023-09-19 | 아게누스 인코포레이티드 | 항-lag-3 항체 및 이의 사용 방법 |
| KR102209364B1 (ko) | 2016-12-09 | 2021-02-01 | 리제너론 파아마슈티컬스, 인크. | T 세포 수용체를 시퀀싱하기 위한 시스템 및 방법 및 이의 용도 |
| CN112020516B (zh) * | 2018-03-13 | 2025-01-03 | 塔斯克疗法有限公司 | 用于肿瘤特异性细胞清除的抗-cd25 |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| JP2022519631A (ja) | 2019-02-12 | 2022-03-24 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 補体および標的抗原に結合する二重特異性抗体を使用するための組成物および方法 |
| RU2734432C1 (ru) | 2019-04-23 | 2020-10-16 | Закрытое Акционерное Общество "Биокад" | Моноклональное антитело, которое специфически связывается с GITR |
| EP4085074A4 (en) * | 2020-01-02 | 2024-05-15 | Nanjing GenScript Biotech Co., Ltd. | ANTI-GITR ANTIBODIES AND THEIR USES |
| KR20210095781A (ko) | 2020-01-24 | 2021-08-03 | 주식회사 에이프릴바이오 | 항원결합 단편 및 생리활성 이펙터 모이어티로 구성된 융합 컨스트럭트를 포함하는 다중결합항체 및 이를 포함하는 약학조성물 |
| MX2022010910A (es) * | 2020-03-06 | 2022-10-07 | Regeneron Pharma | Anticuerpos anti-gitr y usos de estos. |
| WO2022148279A1 (zh) * | 2021-01-08 | 2022-07-14 | 苏州丁孚靶点生物技术有限公司 | 药物产品及其用途 |
| WO2022150654A2 (en) * | 2021-01-08 | 2022-07-14 | 10X Genomics, Inc. | Antigen-binding polypeptides specific for coronaviruses and uses thereof |
| JP7671092B2 (ja) * | 2021-05-10 | 2025-05-01 | メディマブバイオ インコーポレイテッド | 抗ｇｉｔｒ抗体およびその用途 |
| WO2023175614A1 (en) | 2022-03-15 | 2023-09-21 | Yeda Research And Development Co. Ltd. | Anti glucocorticoid-induced tnfr-related (gitr) protein antibodies and uses thereof |
| CN117003883A (zh) * | 2022-04-28 | 2023-11-07 | 北京天广实生物技术股份有限公司 | 结合tigit和vegf的双特异性分子及其用途 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| EP0590058B1 (en) | 1991-06-14 | 2003-11-26 | Genentech, Inc. | HUMANIZED Heregulin ANTIBODy |
| DK0920505T3 (da) | 1996-08-16 | 2008-09-08 | Schering Corp | Pattedyrcelleoverfladeantigener og tilhörende reagenser |
| US6111090A (en) | 1996-08-16 | 2000-08-29 | Schering Corporation | Mammalian cell surface antigens; related reagents |
| US6503184B1 (en) | 1997-10-21 | 2003-01-07 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2 |
| US6689607B2 (en) | 1997-10-21 | 2004-02-10 | Human Genome Sciences, Inc. | Human tumor, necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2 |
| WO1999025834A1 (en) | 1997-11-18 | 1999-05-27 | Genentech, Inc. | Dna19355 polypeptide, a tumor necrosis factor homolog |
| US7087411B2 (en) | 1999-06-08 | 2006-08-08 | Regeneron Pharmaceuticals, Inc. | Fusion protein capable of binding VEGF |
| EP1462114A1 (en) | 2003-03-28 | 2004-09-29 | Universiteit Utrecht Holding B.V. | Methods and means to suppress symptons of an allergic disease by inhibiting the glucocorticoid-induced tumor necrosis factor receptor (GRIT or TNFRSF18) |
| AU2004244626A1 (en) | 2003-05-23 | 2004-12-09 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | GITR ligand and GITR ligand-related molecules and antibodies and uses thereof |
| US20060099171A1 (en) | 2004-11-05 | 2006-05-11 | Masahide Tone | Mouse glucocorticoid-induced TNF receptor ligand is costimulatory for T cells |
| JP5238936B2 (ja) * | 2005-03-25 | 2013-07-17 | ジーアイティーアール，インク． | Ｇｉｔｒ結合分子およびその使用 |
| WO2007133822A1 (en) | 2006-01-19 | 2007-11-22 | Genzyme Corporation | Gitr antibodies for the treatment of cancer |
| US20100061984A1 (en) | 2006-01-20 | 2010-03-11 | The Trustees Of The University Of Pennsylvania | Compositions and methods for modulation of suppressor t cell activation |
| ATE537190T1 (de) | 2006-06-02 | 2011-12-15 | Regeneron Pharma | Hochaffine antikörper gegen den humanen il-6- rezeptor |
| RU2448979C2 (ru) | 2006-12-14 | 2012-04-27 | Ридженерон Фармасьютикалз, Инк. | Антитела человека к дельта-подобному лиганду-4 человека |
| PT2175884T (pt) | 2007-07-12 | 2016-09-21 | Gitr Inc | Terapias de combinação empregando moléculas de ligação a gitr |
| JO3182B1 (ar) | 2009-07-29 | 2018-03-08 | Regeneron Pharma | مضادات حيوية بشرية عالية الالفة مع تولد الاوعية البشرية - 2 |
| IN2015DN02826A (enExample) | 2009-09-03 | 2015-09-11 | Merck Sharp & Dohme | |
| US20130108641A1 (en) | 2011-09-14 | 2013-05-02 | Sanofi | Anti-gitr antibodies |
| JP6053688B2 (ja) | 2011-10-07 | 2016-12-27 | 国立大学法人三重大学 | キメラ抗原受容体 |
| KR101566539B1 (ko) | 2012-06-08 | 2015-11-05 | 국립암센터 | 신규한 Ｔｈ2 세포 전환용 에피토프 및 이의 용도 |
| AR097306A1 (es) | 2013-08-20 | 2016-03-02 | Merck Sharp & Dohme | Modulación de la inmunidad tumoral |
| TW201605896A (zh) * | 2013-08-30 | 2016-02-16 | 安美基股份有限公司 | Gitr抗原結合蛋白 |
| TWI681969B (zh) | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對ｐｄ-１的人類抗體 |
| LT3148579T (lt) | 2014-05-28 | 2021-05-25 | Agenus Inc. | Anti-gitr antikūnai ir jų panaudojimo būdai |
| PL3151921T3 (pl) | 2014-06-06 | 2020-02-28 | Bristol-Myers Squibb Company | Przeciwciała przeciwko receptorowi indukowanego glukokortykoidami czynnika martwicy nowotworu (gitr) i ich zastosowania |
| RU2017115315A (ru) | 2014-10-03 | 2018-11-08 | Дана-Фарбер Кэнсер Инститьют, Инк. | Антитела к рецептору глюкокортикоид-индуцированного фактора некроза опухоли (gitr) и способы их применения |
| MA41044A (fr) | 2014-10-08 | 2017-08-15 | Novartis Ag | Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer |
| EP3212233B1 (en) | 2014-10-31 | 2020-06-24 | Oncomed Pharmaceuticals, Inc. | Combination therapy for treatment of disease |
| CA3027121A1 (en) | 2016-06-10 | 2017-12-14 | Regeneron Pharmaceuticals, Inc. | Anti-gitr antibodies and uses thereof |
-
2017
- 2017-06-09 CA CA3027121A patent/CA3027121A1/en active Pending
- 2017-06-09 MA MA045233A patent/MA45233A/fr unknown
- 2017-06-09 MX MX2018015350A patent/MX2018015350A/es unknown
- 2017-06-09 EP EP23214299.2A patent/EP4344748A3/en not_active Withdrawn
- 2017-06-09 JP JP2018562357A patent/JP7162535B2/ja active Active
- 2017-06-09 SG SG11201810525XA patent/SG11201810525XA/en unknown
- 2017-06-09 IL IL263273A patent/IL263273B2/en unknown
- 2017-06-09 BR BR112018075434-0A patent/BR112018075434A2/pt not_active Application Discontinuation
- 2017-06-09 WO PCT/US2017/036818 patent/WO2017214548A1/en not_active Ceased
- 2017-06-09 UA UAA201811485A patent/UA128687C2/uk unknown
- 2017-06-09 MY MYPI2018002044A patent/MY200162A/en unknown
- 2017-06-09 US US15/619,068 patent/US10738126B2/en active Active
- 2017-06-09 CN CN201780048899.6A patent/CN109563170B/zh active Active
- 2017-06-09 KR KR1020187036000A patent/KR102495601B1/ko active Active
- 2017-06-09 AU AU2017278193A patent/AU2017278193B9/en active Active
- 2017-06-09 EP EP17731435.8A patent/EP3468999B1/en active Active
-
2018
- 2018-11-22 ZA ZA2018/07920A patent/ZA201807920B/en unknown
- 2018-11-27 PH PH12018502502A patent/PH12018502502A1/en unknown
- 2018-12-07 CL CL2018003515A patent/CL2018003515A1/es unknown
- 2018-12-07 CO CONC2018/0013298A patent/CO2018013298A2/es unknown
- 2018-12-10 MX MX2022014695A patent/MX2022014695A/es unknown
-
2020
- 2020-06-26 US US16/913,963 patent/US11414494B2/en active Active
-
2022
- 2022-07-13 US US17/812,256 patent/US20230042324A1/en not_active Abandoned
- 2022-08-17 JP JP2022130091A patent/JP2022159476A/ja active Pending
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