JP2019520412A5 - - Google Patents
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- Publication number
- JP2019520412A5 JP2019520412A5 JP2019500778A JP2019500778A JP2019520412A5 JP 2019520412 A5 JP2019520412 A5 JP 2019520412A5 JP 2019500778 A JP2019500778 A JP 2019500778A JP 2019500778 A JP2019500778 A JP 2019500778A JP 2019520412 A5 JP2019520412 A5 JP 2019520412A5
- Authority
- JP
- Japan
- Prior art keywords
- pyridin
- imidazo
- phenyl
- amine
- piperazin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CCC*(*(C)CC)C(C=C[C@@](C)(C=C(C)C(NC1=NC=*CC)=NC1=C)[Rh])=C Chemical compound CCC*(*(C)CC)C(C=C[C@@](C)(C=C(C)C(NC1=NC=*CC)=NC1=C)[Rh])=C 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16178928.4 | 2016-07-11 | ||
| EP16178928 | 2016-07-11 | ||
| PCT/EP2017/067262 WO2018011138A1 (en) | 2016-07-11 | 2017-07-10 | 2-phenylimidazo[4,5-b]pyridin-7-amine derivates useful as inhibitors of mammalian tyrosine kinase ror1 activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019520412A JP2019520412A (ja) | 2019-07-18 |
| JP2019520412A5 true JP2019520412A5 (enExample) | 2020-07-27 |
| JP6891262B2 JP6891262B2 (ja) | 2021-06-18 |
Family
ID=56409027
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019500778A Expired - Fee Related JP6891262B2 (ja) | 2016-07-11 | 2017-07-10 | 哺乳動物のチロシンキナーゼｒｏｒ１活性の阻害剤として有用な２−フェニルイミダゾ［４，５−ｂ］ピリジン−７−アミン誘導体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11008318B2 (enExample) |
| EP (1) | EP3481824B1 (enExample) |
| JP (1) | JP6891262B2 (enExample) |
| KR (1) | KR102466810B1 (enExample) |
| CN (1) | CN109563092B (enExample) |
| ES (1) | ES2899113T3 (enExample) |
| WO (1) | WO2018011138A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201710835D0 (en) | 2017-07-05 | 2017-08-16 | Ucl Business Plc | ROR1 Antibodies |
| GB201710836D0 (en) | 2017-07-05 | 2017-08-16 | Ucl Business Plc | ROR1 Car T-Cells |
| GB201710838D0 (en) | 2017-07-05 | 2017-08-16 | Ucl Business Plc | Bispecific antibodies |
| EP3589632B1 (en) * | 2018-02-23 | 2020-09-23 | FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. | Novel inhibitors of bacterial glutaminyl cyclases for use in the treatment of periodontal and related diseases |
| CN112574176B (zh) * | 2019-09-27 | 2024-03-15 | 隆泰申医药科技(南京)有限公司 | 一种杂芳基类化合物及其应用 |
| JP7700218B2 (ja) * | 2020-09-17 | 2025-06-30 | 浙江海正薬業股▲ふん▼有限公司 | ピペラジン誘導体、その製造方法、およびその使用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002349477A1 (en) | 2001-11-26 | 2003-06-10 | Takeda Chemical Industries, Ltd. | Bicyclic derivative, process for producing the same, and use |
| SE0202462D0 (sv) * | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | Novel use |
| SE0202464D0 (sv) | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | Use of compounds |
| US7786113B2 (en) | 2004-12-23 | 2010-08-31 | Hoffman-La Roche Inc. | Heterocyclic carbamate derivatives, their manufacture and use as pharmaceutical agents |
| EP1833829A2 (en) | 2004-12-23 | 2007-09-19 | F. Hoffmann-Roche AG | Benzamide substituted imidazo- and pyrrolo-pyridines as protein kinase inhibitors |
| AU2006209117B2 (en) | 2005-01-28 | 2009-12-10 | Daewoong Pharmaceutical Co., Ltd. | Novel benzoimidazole derivatives and pharmaceutical composition comprising the same |
| JP2008542247A (ja) | 2005-05-24 | 2008-11-27 | アストラゼネカ アクチボラグ | グルコキナーゼモジュレーターとしての２−フェニル置換イミダゾール［４，５ｂ］ピリジン／ピラジンおよびプリン誘導体 |
| JP2007063225A (ja) | 2005-09-01 | 2007-03-15 | Takeda Chem Ind Ltd | イミダゾピリジン化合物 |
| US8088761B2 (en) | 2005-12-22 | 2012-01-03 | Cancer Research Technology Limited | Enzyme inhibitors |
| CA2637392A1 (en) | 2006-01-23 | 2007-07-26 | Crystalgenomics, Inc. | Imidazopyridine derivatives inhibiting protein kinase activity, method for the preparation thereof and pharmaceutical composition containing same |
| WO2008121064A1 (en) | 2007-03-30 | 2008-10-09 | Astrazeneca Ab | New imidazo[4,5-b]pyridine-6-halo-7-aryl/heteroaryl compounds 705 |
| WO2008121063A1 (en) | 2007-03-30 | 2008-10-09 | Astrazeneca Ab | New imidazo[ 4,5-b]pyridine-7-carboxamides 704 |
| WO2009001021A1 (en) | 2007-06-26 | 2008-12-31 | Chroma Therapeutics Ltd. | Imidazopyridine derivatives useful as enzyme inhibitors for the treatment of cell proliferative and autoimmune diseases |
| US20110003809A1 (en) | 2008-02-29 | 2011-01-06 | Array Biopharma Inc. | Imidazo [4,5-b] pyridine derivatives used as raf inhibitors |
| WO2011066211A1 (en) | 2009-11-24 | 2011-06-03 | Glaxosmithkline Llc | Azabenzimidazoles as fatty acid synthase inhibitors |
| WO2011079902A2 (en) | 2009-12-18 | 2011-07-07 | Biolnvent International Ab | Biological materials and uses thereof |
| KR20130076046A (ko) * | 2011-12-28 | 2013-07-08 | 한미약품 주식회사 | 타이로신 카이네이즈 억제 활성을 갖는 신규 이미다조피리딘 유도체 |
| WO2013116291A1 (en) | 2012-01-30 | 2013-08-08 | Cephalon, Inc. | Imidazo [4, 5 - b] pyridine derivatives as alk and jak modulators for the treatment of proliferative disorders |
| US9925193B2 (en) * | 2012-11-20 | 2018-03-27 | Proqinase Gmbh | Thioether derivatives as protein kinase inhibitors |
| BR112017016428B1 (pt) * | 2015-02-02 | 2023-10-24 | Kancera Ab | Composto ou sal farmaceuticamente aceitável, composição farmacêutica, e, uso de um composto ou sal farmaceuticamente aceitável |
-
2017
- 2017-07-10 CN CN201780043024.7A patent/CN109563092B/zh not_active Expired - Fee Related
- 2017-07-10 WO PCT/EP2017/067262 patent/WO2018011138A1/en not_active Ceased
- 2017-07-10 KR KR1020197003657A patent/KR102466810B1/ko active Active
- 2017-07-10 EP EP17735582.3A patent/EP3481824B1/en not_active Not-in-force
- 2017-07-10 JP JP2019500778A patent/JP6891262B2/ja not_active Expired - Fee Related
- 2017-07-10 ES ES17735582T patent/ES2899113T3/es active Active
- 2017-07-10 US US16/314,708 patent/US11008318B2/en not_active Expired - Fee Related
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