JP2019517474A5 - - Google Patents
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- Publication number
- JP2019517474A5 JP2019517474A5 JP2018562061A JP2018562061A JP2019517474A5 JP 2019517474 A5 JP2019517474 A5 JP 2019517474A5 JP 2018562061 A JP2018562061 A JP 2018562061A JP 2018562061 A JP2018562061 A JP 2018562061A JP 2019517474 A5 JP2019517474 A5 JP 2019517474A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- independently
- compound
- formula
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims description 47
- 125000000217 alkyl group Chemical group 0.000 claims description 28
- 125000002877 alkyl aryl group Chemical group 0.000 claims description 22
- 125000003710 aryl alkyl group Chemical group 0.000 claims description 22
- 125000003118 aryl group Chemical group 0.000 claims description 22
- 125000001475 halogen functional group Chemical group 0.000 claims description 18
- 125000000623 heterocyclic group Chemical group 0.000 claims description 16
- -1 OR 6 Chemical group 0.000 claims description 8
- 239000000651 prodrug Substances 0.000 claims description 5
- 229940002612 prodrug Drugs 0.000 claims description 5
- 150000003839 salts Chemical class 0.000 claims description 5
- 239000012453 solvate Substances 0.000 claims description 5
- 229910052799 carbon Inorganic materials 0.000 claims description 4
- 125000004432 carbon atom Chemical group C* 0.000 claims description 4
- 206010028980 Neoplasm Diseases 0.000 claims description 3
- 201000011510 cancer Diseases 0.000 claims description 3
- 239000008194 pharmaceutical composition Substances 0.000 claims description 3
- 239000003814 drug Substances 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- 0 C[C@](CCC#CCCC1C(*)C[C@@](C)C(*)CC(*C(I)=*)CC(*)CC(CC2)[C@]2C(*)*1)C(C(*)c1c(*)c(*)ccc1)=* Chemical compound C[C@](CCC#CCCC1C(*)C[C@@](C)C(*)CC(*C(I)=*)CC(*)CC(CC2)[C@]2C(*)*1)C(C(*)c1c(*)c(*)ccc1)=* 0.000 description 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022097794A JP7641933B2 (ja) | 2016-05-27 | 2022-06-17 | カリスポンジオリド、その類似体、およびそれらの使用 |
| JP2024143999A JP2024164181A (ja) | 2016-05-27 | 2024-08-26 | カリスポンジオリド、その類似体、およびそれらの使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662342601P | 2016-05-27 | 2016-05-27 | |
| US62/342,601 | 2016-05-27 | ||
| PCT/US2017/034760 WO2017205791A1 (en) | 2016-05-27 | 2017-05-26 | Callyspongiolide, analogs thereof and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022097794A Division JP7641933B2 (ja) | 2016-05-27 | 2022-06-17 | カリスポンジオリド、その類似体、およびそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019517474A JP2019517474A (ja) | 2019-06-24 |
| JP2019517474A5 true JP2019517474A5 (enExample) | 2020-06-18 |
| JP7502846B2 JP7502846B2 (ja) | 2024-06-19 |
Family
ID=60411563
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018562061A Active JP7502846B2 (ja) | 2016-05-27 | 2017-05-26 | カリスポンジオリド、その類似体、およびそれらの使用 |
| JP2022097794A Active JP7641933B2 (ja) | 2016-05-27 | 2022-06-17 | カリスポンジオリド、その類似体、およびそれらの使用 |
| JP2024143999A Withdrawn JP2024164181A (ja) | 2016-05-27 | 2024-08-26 | カリスポンジオリド、その類似体、およびそれらの使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022097794A Active JP7641933B2 (ja) | 2016-05-27 | 2022-06-17 | カリスポンジオリド、その類似体、およびそれらの使用 |
| JP2024143999A Withdrawn JP2024164181A (ja) | 2016-05-27 | 2024-08-26 | カリスポンジオリド、その類似体、およびそれらの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10875836B2 (enExample) |
| EP (1) | EP3463579B1 (enExample) |
| JP (3) | JP7502846B2 (enExample) |
| KR (1) | KR102481799B1 (enExample) |
| CN (2) | CN118812488A (enExample) |
| CA (1) | CA3025178A1 (enExample) |
| WO (1) | WO2017205791A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118812488A (zh) | 2016-05-27 | 2024-10-22 | 普渡研究基金会 | 美丽海绵内酯、其类似物及其用途 |
| WO2024021261A1 (zh) * | 2022-07-29 | 2024-02-01 | 上海皓元医药股份有限公司 | 一种艾日布林中间体的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104177209B (zh) * | 2014-08-05 | 2015-12-02 | 太原理工大学 | 一种芳基末端炔的制备方法 |
| CN105777702B (zh) * | 2016-03-31 | 2018-02-13 | 北京大学深圳研究生院 | Callyspongiolide立体异构体的合成及抗癌应用 |
| CN118812488A (zh) | 2016-05-27 | 2024-10-22 | 普渡研究基金会 | 美丽海绵内酯、其类似物及其用途 |
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2017
- 2017-05-26 CN CN202410801829.5A patent/CN118812488A/zh active Pending
- 2017-05-26 CN CN201780032805.6A patent/CN109195666A/zh active Pending
- 2017-05-26 KR KR1020187037211A patent/KR102481799B1/ko active Active
- 2017-05-26 US US16/304,652 patent/US10875836B2/en active Active
- 2017-05-26 JP JP2018562061A patent/JP7502846B2/ja active Active
- 2017-05-26 EP EP17803698.4A patent/EP3463579B1/en active Active
- 2017-05-26 CA CA3025178A patent/CA3025178A1/en active Pending
- 2017-05-26 WO PCT/US2017/034760 patent/WO2017205791A1/en not_active Ceased
-
2022
- 2022-06-17 JP JP2022097794A patent/JP7641933B2/ja active Active
-
2024
- 2024-08-26 JP JP2024143999A patent/JP2024164181A/ja not_active Withdrawn