JP2019516981A5 - - Google Patents
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- JP2019516981A5 JP2019516981A5 JP2018559285A JP2018559285A JP2019516981A5 JP 2019516981 A5 JP2019516981 A5 JP 2019516981A5 JP 2018559285 A JP2018559285 A JP 2018559285A JP 2018559285 A JP2018559285 A JP 2018559285A JP 2019516981 A5 JP2019516981 A5 JP 2019516981A5
- Authority
- JP
- Japan
- Prior art keywords
- biomarkers
- pancreatic cancer
- biomarkers listed
- amount
- listed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000000090 biomarker Substances 0.000 claims 49
- 238000000034 method Methods 0.000 claims 26
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 24
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 24
- 201000002528 pancreatic cancer Diseases 0.000 claims 24
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 24
- 239000000523 sample Substances 0.000 claims 10
- 239000011230 binding agent Substances 0.000 claims 5
- 239000013068 control sample Substances 0.000 claims 5
- 230000001575 pathological effect Effects 0.000 claims 5
- 102000004169 proteins and genes Human genes 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- 239000012634 fragment Substances 0.000 claims 4
- -1 PRD14 Proteins 0.000 claims 3
- 229960002685 biotin Drugs 0.000 claims 2
- 235000020958 biotin Nutrition 0.000 claims 2
- 239000011616 biotin Substances 0.000 claims 2
- 239000000975 dye Substances 0.000 claims 2
- 206010052747 Adenocarcinoma pancreas Diseases 0.000 claims 1
- 102000005666 Apolipoprotein A-I Human genes 0.000 claims 1
- 108010059886 Apolipoprotein A-I Proteins 0.000 claims 1
- 102100036781 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 Human genes 0.000 claims 1
- 101710100452 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 Proteins 0.000 claims 1
- 102100021943 C-C motif chemokine 2 Human genes 0.000 claims 1
- 101710155857 C-C motif chemokine 2 Proteins 0.000 claims 1
- 101100439046 Caenorhabditis elegans cdk-2 gene Proteins 0.000 claims 1
- 241000839426 Chlamydia virus Chp1 Species 0.000 claims 1
- 101150029707 ERBB2 gene Proteins 0.000 claims 1
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 1
- 102100039620 Granulocyte-macrophage colony-stimulating factor Human genes 0.000 claims 1
- 101001065609 Homo sapiens Lumican Proteins 0.000 claims 1
- 101000950695 Homo sapiens Mitogen-activated protein kinase 8 Proteins 0.000 claims 1
- 101000992396 Homo sapiens Oxysterol-binding protein-related protein 3 Proteins 0.000 claims 1
- 101000591211 Homo sapiens Receptor-type tyrosine-protein phosphatase O Proteins 0.000 claims 1
- 101000695838 Homo sapiens Receptor-type tyrosine-protein phosphatase U Proteins 0.000 claims 1
- 101001099058 Homo sapiens Serine/threonine-protein phosphatase PGAM5, mitochondrial Proteins 0.000 claims 1
- 101000934996 Homo sapiens Tyrosine-protein kinase JAK3 Proteins 0.000 claims 1
- 108060003951 Immunoglobulin Proteins 0.000 claims 1
- 108010064593 Intercellular Adhesion Molecule-1 Proteins 0.000 claims 1
- 102100037877 Intercellular adhesion molecule 1 Human genes 0.000 claims 1
- 102000003815 Interleukin-11 Human genes 0.000 claims 1
- 108090000177 Interleukin-11 Proteins 0.000 claims 1
- 102000013462 Interleukin-12 Human genes 0.000 claims 1
- 108010065805 Interleukin-12 Proteins 0.000 claims 1
- 108010002386 Interleukin-3 Proteins 0.000 claims 1
- 108090001005 Interleukin-6 Proteins 0.000 claims 1
- 102000004889 Interleukin-6 Human genes 0.000 claims 1
- 108010002586 Interleukin-7 Proteins 0.000 claims 1
- 108090001007 Interleukin-8 Proteins 0.000 claims 1
- 108010002335 Interleukin-9 Proteins 0.000 claims 1
- 108010007622 LDL Lipoproteins Proteins 0.000 claims 1
- 102100032114 Lumican Human genes 0.000 claims 1
- 102100037808 Mitogen-activated protein kinase 8 Human genes 0.000 claims 1
- 102100034256 Mucin-1 Human genes 0.000 claims 1
- 108010008707 Mucin-1 Proteins 0.000 claims 1
- 102100032154 Oxysterol-binding protein-related protein 3 Human genes 0.000 claims 1
- 102100034086 Receptor-type tyrosine-protein phosphatase O Human genes 0.000 claims 1
- 108010044012 STAT1 Transcription Factor Proteins 0.000 claims 1
- 102100038901 Serine/threonine-protein phosphatase PGAM5, mitochondrial Human genes 0.000 claims 1
- 102100029904 Signal transducer and activator of transcription 1-alpha/beta Human genes 0.000 claims 1
- 108010090804 Streptavidin Proteins 0.000 claims 1
- 102100025387 Tyrosine-protein kinase JAK3 Human genes 0.000 claims 1
- 101150063583 UBP7 gene Proteins 0.000 claims 1
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 1
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 1
- 210000000941 bile Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 210000000481 breast Anatomy 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- 102000018358 immunoglobulin Human genes 0.000 claims 1
- 238000002372 labelling Methods 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 201000002094 pancreatic adenocarcinoma Diseases 0.000 claims 1
- 201000008129 pancreatic ductal adenocarcinoma Diseases 0.000 claims 1
- 210000004923 pancreatic tissue Anatomy 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 239000013641 positive control Substances 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021106544A JP2021165745A (ja) | 2016-05-10 | 2021-06-28 | 方法、アレイ、およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1608192.9A GB201608192D0 (en) | 2016-05-10 | 2016-05-10 | Method, array and use thereof |
| GB1608192.9 | 2016-05-10 | ||
| PCT/EP2017/061202 WO2017194613A2 (en) | 2016-05-10 | 2017-05-10 | Method, array and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021106544A Division JP2021165745A (ja) | 2016-05-10 | 2021-06-28 | 方法、アレイ、およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019516981A JP2019516981A (ja) | 2019-06-20 |
| JP2019516981A5 true JP2019516981A5 (enExample) | 2020-06-25 |
Family
ID=56297465
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018559285A Pending JP2019516981A (ja) | 2016-05-10 | 2017-05-10 | 方法、アレイ、およびその使用 |
| JP2021106544A Pending JP2021165745A (ja) | 2016-05-10 | 2021-06-28 | 方法、アレイ、およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021106544A Pending JP2021165745A (ja) | 2016-05-10 | 2021-06-28 | 方法、アレイ、およびその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20200011872A1 (enExample) |
| EP (2) | EP3455632A2 (enExample) |
| JP (2) | JP2019516981A (enExample) |
| KR (1) | KR20190005858A (enExample) |
| CN (1) | CN109564221A (enExample) |
| AU (1) | AU2017261762A1 (enExample) |
| BR (1) | BR112018073178A2 (enExample) |
| CA (1) | CA3022022A1 (enExample) |
| GB (1) | GB201608192D0 (enExample) |
| IL (1) | IL262824A (enExample) |
| MX (1) | MX2018013621A (enExample) |
| RU (1) | RU2018138639A (enExample) |
| WO (1) | WO2017194613A2 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008117067A2 (en) | 2007-03-27 | 2008-10-02 | Carl Arne Krister Borrebaeck | Protein signature/markers for the detection of adenocarcinoma |
| MX2019013517A (es) | 2017-05-24 | 2020-08-17 | Pandion Operations Inc | Inmunotolerancia dirigida. |
| US10174091B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
| US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| EP3972992A4 (en) | 2019-05-20 | 2023-07-19 | Pandion Operations, Inc. | MADCAM TARGETED IMMUNOTLERANCE |
| WO2021168079A1 (en) | 2020-02-21 | 2021-08-26 | Pandion Operations, Inc. | Tissue targeted immunotolerance with a cd39 effector |
| GB202010970D0 (en) | 2020-07-16 | 2020-09-02 | Immunovia Ab | Methods, arrays and uses thereof |
| WO2022109105A1 (en) * | 2020-11-18 | 2022-05-27 | Pandion Operations, Inc. | Madcam targeted therapeutics and uses thereof |
| CA3202255A1 (en) | 2020-12-21 | 2022-06-30 | Hayley WARSINSKE | Markers for the early detection of colon cell proliferative disorders |
| WO2022204332A1 (en) * | 2021-03-24 | 2022-09-29 | Combangio, Inc. | Compositions comprising c-met agonist antibodies and methods for use in ocular treatment |
| CN117305244B (zh) * | 2023-03-28 | 2025-02-28 | 湖南省肿瘤医院 | 人胰腺癌细胞株及其应用 |
| CN120177800B (zh) * | 2025-05-23 | 2025-10-10 | 四川大学 | 血液生物标志物cfp在制备急性胰腺炎诊断试剂的应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0039578B1 (en) | 1980-05-02 | 1985-04-10 | Edward P. Davis | Leg aid device |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4486530A (en) | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
| US5856090A (en) | 1994-09-09 | 1999-01-05 | The Scripps Research Institute | DNA-methylase linking reaction |
| GB9703369D0 (en) | 1997-02-18 | 1997-04-09 | Lindqvist Bjorn H | Process |
| ATE419533T1 (de) * | 2002-10-31 | 2009-01-15 | Hoffmann La Roche | Verfahren/präparat zur erkennung von pankreaskrebs |
| US9005613B2 (en) * | 2003-06-16 | 2015-04-14 | Immunomedics, Inc. | Anti-mucin antibodies for early detection and treatment of pancreatic cancer |
| WO2007013360A2 (en) * | 2005-07-27 | 2007-02-01 | Oncotherapy Science, Inc. | Pancreatic cancer related gene cst6 and gabrp |
| WO2008117067A2 (en) * | 2007-03-27 | 2008-10-02 | Carl Arne Krister Borrebaeck | Protein signature/markers for the detection of adenocarcinoma |
| JP5931874B2 (ja) * | 2010-08-13 | 2016-06-08 | ソマロジック・インコーポレーテッド | 膵癌バイオマーカーおよびその使用 |
| GB201103726D0 (en) * | 2011-03-04 | 2011-04-20 | Immunovia Ab | Method, array and use thereof |
| WO2013052480A1 (en) * | 2011-10-03 | 2013-04-11 | The Board Of Regents Of The University Of Texas System | Marker-based prognostic risk score in colon cancer |
| WO2013106844A2 (en) * | 2012-01-13 | 2013-07-18 | Oncocyte Corporation | Methods and compositions for the treatment and diaginosis of pancreatic cancer |
| KR20140094180A (ko) * | 2013-01-21 | 2014-07-30 | 연세대학교 산학협력단 | 보체인자 b 단백질에 특이적으로 결합하는 폴리펩타이드 또는 항체를 포함하는 췌장암 진단용 조성물 |
| CA2902841A1 (en) * | 2013-03-13 | 2014-10-02 | Creatics Llc | Methods and compositions for detecting pancreatic cancer |
| CN105102637B (zh) * | 2013-04-17 | 2018-05-22 | Lg电子株式会社 | 提取胰腺癌诊断生物标志物的方法、用于该方法的计算装置、胰腺癌诊断生物标志物以及包含该生物标志物的胰腺癌诊断装置 |
| EP3054298B1 (en) * | 2013-10-01 | 2019-02-20 | Toray Industries, Inc. | Method for detecting pancreatic tumor |
| GB201319878D0 (en) * | 2013-11-11 | 2013-12-25 | Immunovia Ab | Method, Array and use thereof |
| WO2015171736A2 (en) * | 2014-05-07 | 2015-11-12 | University Of Utah Research Foundation | Biomarkers and methods for diagnosis of early stage pancreatic ductal adenocarcinoma |
| KR20150129932A (ko) * | 2014-05-12 | 2015-11-23 | 연세대학교 산학협력단 | 보체인자 b 단백질에 특이적으로 결합하는 항체를 포함하는 췌장암 진단용 키트 |
| CN105092845A (zh) * | 2015-07-10 | 2015-11-25 | 深圳市贝沃德克生物技术研究院有限公司 | 胰腺癌蛋白生物标记物、用途及其检测芯片和检测装置 |
| GB201516801D0 (en) * | 2015-09-22 | 2015-11-04 | Immunovia Ab | Method, array and use thereof |
-
2016
- 2016-05-10 GB GBGB1608192.9A patent/GB201608192D0/en not_active Ceased
-
2017
- 2017-05-10 KR KR1020187032184A patent/KR20190005858A/ko not_active Abandoned
- 2017-05-10 RU RU2018138639A patent/RU2018138639A/ru not_active Application Discontinuation
- 2017-05-10 CN CN201780028945.6A patent/CN109564221A/zh active Pending
- 2017-05-10 US US16/097,420 patent/US20200011872A1/en not_active Abandoned
- 2017-05-10 CA CA3022022A patent/CA3022022A1/en not_active Abandoned
- 2017-05-10 BR BR112018073178-1A patent/BR112018073178A2/pt not_active IP Right Cessation
- 2017-05-10 EP EP17725897.7A patent/EP3455632A2/en not_active Withdrawn
- 2017-05-10 EP EP21171277.3A patent/EP3907509A3/en not_active Withdrawn
- 2017-05-10 AU AU2017261762A patent/AU2017261762A1/en not_active Abandoned
- 2017-05-10 JP JP2018559285A patent/JP2019516981A/ja active Pending
- 2017-05-10 WO PCT/EP2017/061202 patent/WO2017194613A2/en not_active Ceased
- 2017-05-10 MX MX2018013621A patent/MX2018013621A/es unknown
-
2018
- 2018-11-06 IL IL262824A patent/IL262824A/en unknown
-
2021
- 2021-06-28 JP JP2021106544A patent/JP2021165745A/ja active Pending
- 2021-12-08 US US17/545,076 patent/US20220206004A1/en not_active Abandoned
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