JP2020507760A5 - - Google Patents
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- Publication number
- JP2020507760A5 JP2020507760A5 JP2019541330A JP2019541330A JP2020507760A5 JP 2020507760 A5 JP2020507760 A5 JP 2020507760A5 JP 2019541330 A JP2019541330 A JP 2019541330A JP 2019541330 A JP2019541330 A JP 2019541330A JP 2020507760 A5 JP2020507760 A5 JP 2020507760A5
- Authority
- JP
- Japan
- Prior art keywords
- pancreatic cancer
- biomarkers
- optionally
- sample
- array
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000090 biomarker Substances 0.000 claims 27
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 26
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 26
- 201000002528 pancreatic cancer Diseases 0.000 claims 26
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 26
- 238000000034 method Methods 0.000 claims 18
- 239000000523 sample Substances 0.000 claims 17
- 239000000427 antigen Substances 0.000 claims 12
- 102000036639 antigens Human genes 0.000 claims 12
- 108091007433 antigens Proteins 0.000 claims 12
- 239000012634 fragment Substances 0.000 claims 12
- 102000004169 proteins and genes Human genes 0.000 claims 7
- 108090000623 proteins and genes Proteins 0.000 claims 7
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 6
- 239000011230 binding agent Substances 0.000 claims 6
- 239000013068 control sample Substances 0.000 claims 5
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 208000009956 adenocarcinoma Diseases 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 108010028778 Complement C4 Proteins 0.000 claims 3
- 108010028773 Complement C5 Proteins 0.000 claims 3
- 102100031506 Complement C5 Human genes 0.000 claims 3
- 229960002685 biotin Drugs 0.000 claims 3
- 235000020958 biotin Nutrition 0.000 claims 3
- 239000011616 biotin Substances 0.000 claims 3
- 210000002966 serum Anatomy 0.000 claims 3
- 208000000668 Chronic Pancreatitis Diseases 0.000 claims 2
- 108060003951 Immunoglobulin Proteins 0.000 claims 2
- 206010033649 Pancreatitis chronic Diseases 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 239000000975 dye Substances 0.000 claims 2
- 102000018358 immunoglobulin Human genes 0.000 claims 2
- 230000003211 malignant effect Effects 0.000 claims 2
- 201000008129 pancreatic ductal adenocarcinoma Diseases 0.000 claims 2
- 230000007170 pathology Effects 0.000 claims 2
- 210000002381 plasma Anatomy 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 206010052747 Adenocarcinoma pancreas Diseases 0.000 claims 1
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 1
- 206010073365 Intraductal papillary mucinous carcinoma of pancreas Diseases 0.000 claims 1
- 206010055006 Pancreatic sarcoma Diseases 0.000 claims 1
- 108010090804 Streptavidin Proteins 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 210000000941 bile Anatomy 0.000 claims 1
- 229940098773 bovine serum albumin Drugs 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- 238000002372 labelling Methods 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 claims 1
- 208000014018 liver neoplasm Diseases 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 238000002493 microarray Methods 0.000 claims 1
- 239000008267 milk Substances 0.000 claims 1
- 210000004080 milk Anatomy 0.000 claims 1
- 235000013336 milk Nutrition 0.000 claims 1
- 208000022669 mucinous neoplasm Diseases 0.000 claims 1
- 239000013642 negative control Substances 0.000 claims 1
- 201000002526 pancreas sarcoma Diseases 0.000 claims 1
- 201000002094 pancreatic adenocarcinoma Diseases 0.000 claims 1
- 201000004754 pancreatic intraductal papillary-mucinous neoplasm Diseases 0.000 claims 1
- 210000004923 pancreatic tissue Anatomy 0.000 claims 1
- 239000002953 phosphate buffered saline Substances 0.000 claims 1
- 239000013641 positive control Substances 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1701572.8A GB201701572D0 (en) | 2017-01-31 | 2017-01-31 | Methods, arrays and uses thereof |
| GB1701572.8 | 2017-01-31 | ||
| PCT/EP2018/052423 WO2018141804A1 (en) | 2017-01-31 | 2018-01-31 | Methods, arrays and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020507760A JP2020507760A (ja) | 2020-03-12 |
| JP2020507760A5 true JP2020507760A5 (enExample) | 2021-03-18 |
Family
ID=58462729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019541330A Pending JP2020507760A (ja) | 2017-01-31 | 2018-01-31 | 方法、アレイ、およびそれらの使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20190382849A1 (enExample) |
| EP (1) | EP3577464A1 (enExample) |
| JP (1) | JP2020507760A (enExample) |
| KR (1) | KR20190109422A (enExample) |
| CN (1) | CN110325860A (enExample) |
| AU (1) | AU2018214180A1 (enExample) |
| BR (1) | BR112019015633A2 (enExample) |
| CA (1) | CA3051968A1 (enExample) |
| GB (1) | GB201701572D0 (enExample) |
| IL (1) | IL268244A (enExample) |
| MX (1) | MX2019008911A (enExample) |
| RU (1) | RU2019123695A (enExample) |
| WO (1) | WO2018141804A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008117067A2 (en) | 2007-03-27 | 2008-10-02 | Carl Arne Krister Borrebaeck | Protein signature/markers for the detection of adenocarcinoma |
| CA3142634A1 (en) * | 2019-07-03 | 2021-01-07 | Crystal Bioscience Inc. | Anti-b7-h3 antibody and methods of use thereof |
| KR102289278B1 (ko) * | 2019-07-09 | 2021-08-13 | 주식회사 베르티스 | 췌장암 진단용 바이오마커 패널 및 그 용도 |
| JP2023507369A (ja) * | 2019-12-20 | 2023-02-22 | メディミューン，エルエルシー | グリピカン３を標的とするキメラ抗原受容体を用いて癌を治療する組成物及び方法 |
| GB202010970D0 (en) | 2020-07-16 | 2020-09-02 | Immunovia Ab | Methods, arrays and uses thereof |
| AU2022244125A1 (en) * | 2021-03-26 | 2023-10-19 | BioNTech SE | Combination therapy with an anti-ca19-9 antibody and folfirinox in the treatment of cancer |
| CN113336851B (zh) * | 2021-06-30 | 2021-12-24 | 徐州医科大学 | 新型全人源抗人b7h3抗体、包含所述抗体的组合物及其应用 |
| CN120177800B (zh) * | 2025-05-23 | 2025-10-10 | 四川大学 | 血液生物标志物cfp在制备急性胰腺炎诊断试剂的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4486530A (en) | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US8632983B2 (en) * | 2005-04-15 | 2014-01-21 | Van Andel Research Institute | Biomarkers for pancreatic cancer and diagnostic methods |
| WO2008117067A2 (en) | 2007-03-27 | 2008-10-02 | Carl Arne Krister Borrebaeck | Protein signature/markers for the detection of adenocarcinoma |
| WO2012031374A1 (zh) * | 2010-09-09 | 2012-03-15 | 北京同为时代生物技术有限公司 | 用于诊断上皮源性癌症的血液标志物及其单克隆抗体 |
| GB201103726D0 (en) | 2011-03-04 | 2011-04-20 | Immunovia Ab | Method, array and use thereof |
| GB201206323D0 (en) * | 2012-04-10 | 2012-05-23 | Immunovia Ab | Methods and arrays for use in the same |
| GB201319878D0 (en) * | 2013-11-11 | 2013-12-25 | Immunovia Ab | Method, Array and use thereof |
| GB201516801D0 (en) * | 2015-09-22 | 2015-11-04 | Immunovia Ab | Method, array and use thereof |
-
2017
- 2017-01-31 GB GBGB1701572.8A patent/GB201701572D0/en not_active Ceased
-
2018
- 2018-01-31 CN CN201880009309.3A patent/CN110325860A/zh active Pending
- 2018-01-31 JP JP2019541330A patent/JP2020507760A/ja active Pending
- 2018-01-31 BR BR112019015633-0A patent/BR112019015633A2/pt not_active Application Discontinuation
- 2018-01-31 RU RU2019123695A patent/RU2019123695A/ru not_active Application Discontinuation
- 2018-01-31 MX MX2019008911A patent/MX2019008911A/es unknown
- 2018-01-31 KR KR1020197022175A patent/KR20190109422A/ko not_active Ceased
- 2018-01-31 EP EP18703545.6A patent/EP3577464A1/en not_active Withdrawn
- 2018-01-31 AU AU2018214180A patent/AU2018214180A1/en not_active Abandoned
- 2018-01-31 US US16/479,064 patent/US20190382849A1/en not_active Abandoned
- 2018-01-31 CA CA3051968A patent/CA3051968A1/en not_active Abandoned
- 2018-01-31 WO PCT/EP2018/052423 patent/WO2018141804A1/en not_active Ceased
-
2019
- 2019-07-24 IL IL268244A patent/IL268244A/en unknown
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