JP2019516722A5 - - Google Patents
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- Publication number
- JP2019516722A5 JP2019516722A5 JP2018560617A JP2018560617A JP2019516722A5 JP 2019516722 A5 JP2019516722 A5 JP 2019516722A5 JP 2018560617 A JP2018560617 A JP 2018560617A JP 2018560617 A JP2018560617 A JP 2018560617A JP 2019516722 A5 JP2019516722 A5 JP 2019516722A5
- Authority
- JP
- Japan
- Prior art keywords
- trigeminal
- painful
- trigeminal neuralgia
- general formula
- neuropathy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000020049 trigeminal nerve disease Diseases 0.000 claims 23
- 206010044652 trigeminal neuralgia Diseases 0.000 claims 21
- 239000003814 drug Substances 0.000 claims 10
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 125000000217 alkyl group Chemical group 0.000 claims 9
- 229940079593 drug Drugs 0.000 claims 9
- -1 carbamate compound Chemical class 0.000 claims 7
- 208000007514 Herpes zoster Diseases 0.000 claims 6
- 229910052736 halogen Inorganic materials 0.000 claims 6
- 150000002367 halogens Chemical class 0.000 claims 6
- 150000002431 hydrogen Chemical class 0.000 claims 6
- 229910052739 hydrogen Inorganic materials 0.000 claims 6
- 239000001257 hydrogen Substances 0.000 claims 6
- 125000006731 (C1-C8) thioalkoxy group Chemical group 0.000 claims 3
- 206010016059 Facial pain Diseases 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 3
- 230000001154 acute effect Effects 0.000 claims 3
- 125000003545 alkoxy group Chemical group 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 208000014674 injury Diseases 0.000 claims 3
- 230000003902 lesion Effects 0.000 claims 3
- 201000006417 multiple sclerosis Diseases 0.000 claims 3
- 230000002085 persistent effect Effects 0.000 claims 3
- 230000002265 prevention Effects 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 239000012453 solvate Substances 0.000 claims 3
- 230000008733 trauma Effects 0.000 claims 3
- KXDHJXZQYSOELW-UHFFFAOYSA-N carbonic acid monoamide Natural products NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 claims 2
- 125000004494 ethyl ester group Chemical group 0.000 claims 2
- 238000007918 intramuscular administration Methods 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- KJAMZCVTJDTESW-UHFFFAOYSA-N tiracizine Chemical compound C1CC2=CC=CC=C2N(C(=O)CN(C)C)C2=CC(NC(=O)OCC)=CC=C21 KJAMZCVTJDTESW-UHFFFAOYSA-N 0.000 claims 2
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 claims 1
- 150000004657 carbamic acid derivatives Chemical class 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 150000004677 hydrates Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000001568 sexual effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20160061386 | 2016-05-19 | ||
| KR10-2016-0061386 | 2016-05-19 | ||
| PCT/KR2017/005172 WO2017200317A1 (ko) | 2016-05-19 | 2017-05-18 | 삼차신경통을 예방 또는 치료하기 위한 카바메이트 화합물의 용도 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019516722A JP2019516722A (ja) | 2019-06-20 |
| JP2019516722A5 true JP2019516722A5 (https=) | 2020-07-02 |
| JP6960415B2 JP6960415B2 (ja) | 2021-11-05 |
Family
ID=60325324
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018560617A Active JP6960415B2 (ja) | 2016-05-19 | 2017-05-18 | 三叉神経痛を予防又は治療する目的のためのカルバメート化合物の使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11207295B2 (https=) |
| EP (1) | EP3459542B1 (https=) |
| JP (1) | JP6960415B2 (https=) |
| KR (1) | KR102421013B1 (https=) |
| CN (1) | CN109310669B (https=) |
| AU (1) | AU2017267160B2 (https=) |
| CA (1) | CA3024284C (https=) |
| DK (1) | DK3459542T3 (https=) |
| ES (1) | ES2887338T3 (https=) |
| MX (1) | MX389613B (https=) |
| PL (1) | PL3459542T3 (https=) |
| PT (1) | PT3459542T (https=) |
| RU (1) | RU2751504C2 (https=) |
| WO (1) | WO2017200317A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES3035674T3 (en) | 2016-12-14 | 2025-09-08 | Sk Biopharmaceuticals Co Ltd | Use of carbamate compound for prevention, alleviation, or treatment of demyelinating disease |
| US20220117941A1 (en) * | 2018-09-21 | 2022-04-21 | Sk Biopharmaceuticals Co., Ltd. | Carbamate compound and use of formulation comprising same in preventing, alleviating, or treating acute stress disorder or post-traumatic stress disorder |
| JP7369185B2 (ja) * | 2018-10-19 | 2023-10-25 | エスケー バイオファーマスティカルズ カンパニー リミテッド | カルバメート化合物の糖尿病性末梢神経障害又は化学療法剤誘発性末梢神経障害の予防、緩和又は治療のための使用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3415840A (en) * | 1965-10-22 | 1968-12-10 | American Home Prod | Pyrazole-1-ethanol derivatives |
| DE2628420A1 (de) * | 1976-06-24 | 1978-01-05 | Bayer Ag | 1-acyloxy-2-imidazolyl-1-phenyl- aethane, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide und nematizide |
| US5958949A (en) * | 1996-12-31 | 1999-09-28 | Gpi Nil Holdings Inc. | N-linked ureas and carbamates of piperidyl thioesters |
| WO2002067922A1 (en) * | 2001-02-27 | 2002-09-06 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in the treatment of pain |
| US7598279B2 (en) * | 2005-04-22 | 2009-10-06 | Sk Holdings Co., Ltd. | Neurotherapeutic azole compounds |
| JP4227121B2 (ja) | 2005-06-08 | 2009-02-18 | 独立行政法人科学技術振興機構 | 神経因性疼痛治療剤 |
| PL2445890T3 (pl) | 2009-06-22 | 2016-02-29 | Sk Biopharmaceuticals Co Ltd | Sposób wytwarzania estru (R)-1-arylo-2-tetrazoliloetylowego kwasu karbaminowego |
| US8404461B2 (en) * | 2009-10-15 | 2013-03-26 | SK Biopharmaceutical Co. Ltd. | Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester |
| US20130252924A1 (en) * | 2010-11-11 | 2013-09-26 | Akron Molecules Gmbh | Compounds and Methods for Treating Pain |
| TN2016000497A1 (en) | 2014-05-09 | 2018-04-04 | Tecnimede Sociedade Tecnico Medicinal S | (r)-pirlindole and its pharmaceutically acceptable salts for use in medicine |
-
2017
- 2017-05-16 KR KR1020170060713A patent/KR102421013B1/ko active Active
- 2017-05-18 CA CA3024284A patent/CA3024284C/en active Active
- 2017-05-18 EP EP17799674.1A patent/EP3459542B1/en active Active
- 2017-05-18 US US16/302,860 patent/US11207295B2/en active Active
- 2017-05-18 PT PT177996741T patent/PT3459542T/pt unknown
- 2017-05-18 AU AU2017267160A patent/AU2017267160B2/en active Active
- 2017-05-18 JP JP2018560617A patent/JP6960415B2/ja active Active
- 2017-05-18 CN CN201780030912.5A patent/CN109310669B/zh active Active
- 2017-05-18 WO PCT/KR2017/005172 patent/WO2017200317A1/ko not_active Ceased
- 2017-05-18 DK DK17799674.1T patent/DK3459542T3/da active
- 2017-05-18 RU RU2018144784A patent/RU2751504C2/ru active
- 2017-05-18 MX MX2018014081A patent/MX389613B/es unknown
- 2017-05-18 ES ES17799674T patent/ES2887338T3/es active Active
- 2017-05-18 PL PL17799674T patent/PL3459542T3/pl unknown
-
2021
- 2021-12-02 US US17/457,308 patent/US12611395B2/en active Active
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