JP2019516675A5 - - Google Patents
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- Publication number
- JP2019516675A5 JP2019516675A5 JP2018555634A JP2018555634A JP2019516675A5 JP 2019516675 A5 JP2019516675 A5 JP 2019516675A5 JP 2018555634 A JP2018555634 A JP 2018555634A JP 2018555634 A JP2018555634 A JP 2018555634A JP 2019516675 A5 JP2019516675 A5 JP 2019516675A5
- Authority
- JP
- Japan
- Prior art keywords
- peg
- pharmaceutically acceptable
- acceptable salt
- ala
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662324600P | 2016-04-19 | 2016-04-19 | |
| US62/324,600 | 2016-04-19 | ||
| PCT/CA2017/050475 WO2017181277A1 (en) | 2016-04-19 | 2017-04-18 | Pegylated bioactive peptides and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019516675A JP2019516675A (ja) | 2019-06-20 |
| JP2019516675A5 true JP2019516675A5 (https=) | 2021-11-11 |
| JP7134093B2 JP7134093B2 (ja) | 2022-09-09 |
Family
ID=60039750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018555634A Active JP7134093B2 (ja) | 2016-04-19 | 2017-04-18 | ペグ化バイオアクティブペプチド及びその使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US10918730B2 (https=) |
| EP (1) | EP3445778B1 (https=) |
| JP (1) | JP7134093B2 (https=) |
| KR (1) | KR102520348B1 (https=) |
| CN (1) | CN109153712B (https=) |
| AU (1) | AU2017254754B2 (https=) |
| BR (1) | BR112018070929A2 (https=) |
| CA (1) | CA3021231A1 (https=) |
| DK (1) | DK3445778T3 (https=) |
| ES (1) | ES2824781T3 (https=) |
| HU (1) | HUE052802T2 (https=) |
| IL (1) | IL262356B2 (https=) |
| MX (1) | MX2018012716A (https=) |
| PL (1) | PL3445778T3 (https=) |
| PT (1) | PT3445778T (https=) |
| RU (1) | RU2748576C2 (https=) |
| SG (1) | SG11201808880PA (https=) |
| WO (1) | WO2017181277A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11202110469PA (en) * | 2019-03-29 | 2021-10-28 | Massachusetts Gen Hospital | Ghrh or analogues thereof for use in treatment of hepatic disease |
| JP7542641B2 (ja) | 2020-10-09 | 2024-08-30 | オートリブ ディベロップメント エービー | エアバッグ装置 |
| CN114195881B (zh) * | 2021-12-16 | 2022-09-16 | 浙江湃肽生物股份有限公司 | 一种制备醋酸舍莫瑞林的方法 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4659693A (en) | 1984-04-30 | 1987-04-21 | Syntex (U.S.A.) Inc. | N,N'-dialkyl substituted guanidino amino acyl residue substituted GRF-analog peptides |
| US4622312A (en) | 1984-09-24 | 1986-11-11 | Hoffmann-La Roche Inc. | Growth hormone releasing factor analogs |
| US4689318A (en) | 1985-08-29 | 1987-08-25 | The Salk Institute For Biological Studies | GRF analogs |
| US4914189A (en) | 1987-02-05 | 1990-04-03 | The Adminstrators Of The Tulane Educational Fund | Synthetic GHRH analogs |
| DE3726324A1 (de) | 1987-08-07 | 1989-02-16 | Hoechst Ag | Cyclopeptide als resorptionsfoerderer bei applikation auf die schleimhaeute |
| US5023322A (en) | 1988-08-31 | 1991-06-11 | Mta Kutatas-Es Szervezetelemzo Intezete | Analogs of growth hormone releasing factor (GRF) and a method for the preparation thereof |
| US5084442A (en) | 1988-09-06 | 1992-01-28 | Hoffmann-La Roche Inc. | Cyclic growth hormone releasing factor analogs and method for the manufacture thereof |
| US5137872A (en) | 1989-09-18 | 1992-08-11 | Pitman-Moore, Inc. | Growth hormone-releasing factor analogs |
| EP0544706A4 (en) | 1990-06-29 | 1993-10-13 | Hoffmann-La Roche Inc. | Histidine substituted growth hormone releasing factor analogs |
| US5847006A (en) | 1991-02-08 | 1998-12-08 | Cambridge Neuroscience, Inc. | Therapeutic guanidines |
| CA2084061A1 (en) | 1991-04-09 | 1992-10-10 | Arthur M. Felix | Growth hormone releasing factor analogs |
| CA2158782C (en) | 1994-09-23 | 2010-01-12 | Pierrette Gaudreau | Marker for growth hormone-releasing factor receptors |
| US5792747A (en) | 1995-01-24 | 1998-08-11 | The Administrators Of The Tulane Educational Fund | Highly potent agonists of growth hormone releasing hormone |
| EP0820296A4 (en) | 1995-04-14 | 1999-06-30 | Univ Tulane | ANALOGS OF THE GROWTH HORMONE-RELEASING FACTOR |
| BRPI9608799B8 (pt) | 1995-05-26 | 2019-11-05 | Theratechnologies Inc | análogo pró-grf -corpo graxo quimérico com aumentada potência biológica, e, formulação farmacêutica. |
| EP0922446A1 (en) * | 1997-12-03 | 1999-06-16 | Applied Research Systems Ars Holding N.V. | Solution-phase site-specific preparation of GRF-PEG conjugates |
| US6696063B1 (en) | 1998-12-30 | 2004-02-24 | Applied Research Systems Ars Holding N.V. | Treatment of HIV-associated dysmorphia/dysmetabolic syndrome (HADDS) with or without lipodystrophy |
| AU772752B2 (en) | 1999-07-26 | 2004-05-06 | Baylor College Of Medicine | Super-active porcine growth hormone releasing hormone analog |
| CA2422707A1 (en) | 2000-10-05 | 2002-04-11 | Ares Trading S.A. | Regioselective liquid phase pegylation |
| KR20050071498A (ko) * | 2002-09-18 | 2005-07-07 | 상트르 오스피딸리에 드 루니버시떼 드 몬트리알 | 성장 호르몬 방출 호르몬 유사체 |
| WO2004067548A2 (en) | 2003-01-31 | 2004-08-12 | Theratechnologies Inc. | Chemically modified metabolites of regulatory peptides and methods of producing and using same |
| WO2004105789A1 (en) | 2003-05-29 | 2004-12-09 | Theratechnologies Inc. | Grf analog compositions and their use |
| US8293708B2 (en) * | 2005-08-30 | 2012-10-23 | Novo Nordisk Health Care A/G | Liquid formulations N-terminal serine of pegylated growth hormone |
| EP1834962A1 (de) | 2006-03-15 | 2007-09-19 | Biotecon Therapeutics GmbH | PEGyliertes mutiertes Clostridium botulinum Toxin |
| US20110021429A1 (en) | 2007-10-01 | 2011-01-27 | Pierrette Gaudreau | Renoprotection by growth hormone-releasing hormone and agonists |
| EP2249853A4 (en) * | 2008-01-30 | 2012-12-26 | Univ Indiana Res & Tech Corp | ESTER BASED PEPTIDE PRODRUGS |
| US8796216B2 (en) | 2008-06-12 | 2014-08-05 | Syntaxin Limited | Suppression of neuroendocrine diseases |
| CN102083451A (zh) | 2008-06-12 | 2011-06-01 | 赛恩泰新公司 | 癌症的抑制 |
| CN102348723A (zh) | 2008-12-05 | 2012-02-08 | 安吉奥开米公司 | 肽治疗剂轭合物及其应用 |
| KR20140027284A (ko) * | 2011-04-21 | 2014-03-06 | 쎄러테크놀로지스 인코포레이티드 | 성장 호르몬 방출 인자(grf) 유사체 및 이의 용도 |
| TW201806968A (zh) | 2011-10-18 | 2018-03-01 | 艾利倫治療公司 | 擬肽巨環化合物 |
| US9079974B2 (en) | 2011-12-21 | 2015-07-14 | The University Of Miami | GH-RH analogs with potent agonistic effects |
| CN104946659A (zh) * | 2015-03-27 | 2015-09-30 | 杭州北斗生物技术有限公司 | 重组人生长激素的制备方法及其peg化修饰物的制备方法 |
| US20170037105A1 (en) | 2015-08-03 | 2017-02-09 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
-
2017
- 2017-04-18 WO PCT/CA2017/050475 patent/WO2017181277A1/en not_active Ceased
- 2017-04-18 SG SG11201808880PA patent/SG11201808880PA/en unknown
- 2017-04-18 PL PL17785199.5T patent/PL3445778T3/pl unknown
- 2017-04-18 KR KR1020187033365A patent/KR102520348B1/ko active Active
- 2017-04-18 CN CN201780021914.8A patent/CN109153712B/zh not_active Expired - Fee Related
- 2017-04-18 MX MX2018012716A patent/MX2018012716A/es unknown
- 2017-04-18 ES ES17785199T patent/ES2824781T3/es active Active
- 2017-04-18 HU HUE17785199A patent/HUE052802T2/hu unknown
- 2017-04-18 PT PT177851995T patent/PT3445778T/pt unknown
- 2017-04-18 RU RU2018140501A patent/RU2748576C2/ru active
- 2017-04-18 DK DK17785199.5T patent/DK3445778T3/da active
- 2017-04-18 BR BR112018070929-8A patent/BR112018070929A2/pt not_active IP Right Cessation
- 2017-04-18 AU AU2017254754A patent/AU2017254754B2/en not_active Ceased
- 2017-04-18 JP JP2018555634A patent/JP7134093B2/ja active Active
- 2017-04-18 US US16/094,565 patent/US10918730B2/en active Active
- 2017-04-18 CA CA3021231A patent/CA3021231A1/en active Pending
- 2017-04-18 US US15/490,618 patent/US9988428B2/en active Active
- 2017-04-18 EP EP17785199.5A patent/EP3445778B1/en active Active
-
2018
- 2018-10-14 IL IL262356A patent/IL262356B2/en unknown
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