SG11202110469PA - Ghrh or analogues thereof for use in treatment of hepatic disease - Google Patents

Ghrh or analogues thereof for use in treatment of hepatic disease

Info

Publication number
SG11202110469PA
SG11202110469PA SG11202110469PA SG11202110469PA SG11202110469PA SG 11202110469P A SG11202110469P A SG 11202110469PA SG 11202110469P A SG11202110469P A SG 11202110469PA SG 11202110469P A SG11202110469P A SG 11202110469PA SG 11202110469P A SG11202110469P A SG 11202110469PA
Authority
SG
Singapore
Prior art keywords
ghrh
analogues
treatment
hepatic disease
hepatic
Prior art date
Application number
SG11202110469PA
Inventor
Steven K Grinspoon
Original Assignee
Massachusetts Gen Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Gen Hospital filed Critical Massachusetts Gen Hospital
Publication of SG11202110469PA publication Critical patent/SG11202110469PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/25Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SG11202110469PA 2019-03-29 2020-03-27 Ghrh or analogues thereof for use in treatment of hepatic disease SG11202110469PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962826284P 2019-03-29 2019-03-29
US201962861187P 2019-06-13 2019-06-13
PCT/US2020/025180 WO2020205498A1 (en) 2019-03-29 2020-03-27 Ghrh or analogues thereof for use in treatment of hepatic disease

Publications (1)

Publication Number Publication Date
SG11202110469PA true SG11202110469PA (en) 2021-10-28

Family

ID=72607731

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202110469PA SG11202110469PA (en) 2019-03-29 2020-03-27 Ghrh or analogues thereof for use in treatment of hepatic disease

Country Status (10)

Country Link
US (4) US10799562B1 (en)
EP (1) EP3947426A4 (en)
JP (1) JP2022527190A (en)
KR (1) KR20210145226A (en)
CN (1) CN113646327A (en)
AU (1) AU2020253828A1 (en)
CA (1) CA3133319A1 (en)
IL (1) IL286703A (en)
SG (1) SG11202110469PA (en)
WO (1) WO2020205498A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020205498A1 (en) 2019-03-29 2020-10-08 The General Hospital Corporation Ghrh or analogues thereof for use in treatment of hepatic disease

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2009140731A (en) * 2007-04-04 2011-05-10 Тератекнолоджиз Инк. (Ca) PHARMACEUTICAL COMPOSITIONS CONTAINING GHRH MOLECULES
US9163091B2 (en) * 2007-05-30 2015-10-20 Lpath, Inc. Compositions and methods for binding lysophosphatidic acid
WO2015100423A2 (en) * 2013-12-24 2015-07-02 University Of Miami Methods for treating cancer with ghrh agonists
WO2017066619A1 (en) * 2015-10-16 2017-04-20 Teva Pharmaceutical Industries Ltd. Treatment of non-alcoholic fatty liver disease or non-alcoholic steatohepatitis with delayed-release 6-mercaptopurine
MX2018012716A (en) * 2016-04-19 2019-02-11 Griffon Pharmaceuticals Inc Pegylated bioactive peptides and uses thereof.
US20210059993A1 (en) * 2018-02-14 2021-03-04 Lumos Pharma, Inc. Compositions for the treatment of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis
WO2020205498A1 (en) * 2019-03-29 2020-10-08 The General Hospital Corporation Ghrh or analogues thereof for use in treatment of hepatic disease
CN116801788A (en) * 2020-10-30 2023-09-22 综合医院公司 Kit, reagent and method for assessing liver disease
US20220152012A1 (en) * 2020-11-16 2022-05-19 The Regents Of The University Of California Methods for regressing or reversing fibrosis and/or liver cirrhosis in a subject in need thereof using high-dose niacin, or a niacin analog thereof

Also Published As

Publication number Publication date
US20240091316A1 (en) 2024-03-21
AU2020253828A1 (en) 2021-10-28
IL286703A (en) 2021-10-31
US10799562B1 (en) 2020-10-13
EP3947426A1 (en) 2022-02-09
EP3947426A4 (en) 2023-01-04
US20200405816A1 (en) 2020-12-31
KR20210145226A (en) 2021-12-01
US10946073B2 (en) 2021-03-16
JP2022527190A (en) 2022-05-31
US20210177943A1 (en) 2021-06-17
WO2020205498A1 (en) 2020-10-08
CA3133319A1 (en) 2020-10-08
CN113646327A (en) 2021-11-12
US11738066B2 (en) 2023-08-29
US20200306345A1 (en) 2020-10-01

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