|
US2096948A
(en)
|
1935-12-20 |
1937-10-26 |
Anchor Steel & Conveyor Co |
Conveyer system
|
|
US4741900A
(en)
|
1982-11-16 |
1988-05-03 |
Cytogen Corporation |
Antibody-metal ion complexes
|
|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
|
DE3668186D1
(de)
|
1985-04-01 |
1990-02-15 |
Celltech Ltd |
Transformierte myeloma-zell-linie und dieselbe verwendendes verfahren zur expression eines gens, das ein eukaryontisches polypeptid kodiert.
|
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US4873192A
(en)
|
1987-02-17 |
1989-10-10 |
The United States Of America As Represented By The Department Of Health And Human Services |
Process for site specific mutagenesis without phenotypic selection
|
|
US5892019A
(en)
|
1987-07-15 |
1999-04-06 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Production of a single-gene-encoded immunoglobulin
|
|
GB8717430D0
(en)
|
1987-07-23 |
1987-08-26 |
Celltech Ltd |
Recombinant dna product
|
|
EP0428534B1
(en)
|
1988-06-14 |
1995-03-29 |
Cetus Oncology Corporation |
Coupling agents and sterically hindered disulfide linked conjugates prepared therefrom
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
EP1541682A3
(en)
|
1988-09-02 |
2005-07-06 |
Dyax Corp. |
Generation and selection of recombinant varied binding proteins
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5225538A
(en)
|
1989-02-23 |
1993-07-06 |
Genentech, Inc. |
Lymphocyte homing receptor/immunoglobulin fusion proteins
|
|
US5116964A
(en)
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
|
ZA902949B
(en)
|
1989-05-05 |
1992-02-26 |
Res Dev Foundation |
A novel antibody delivery system for biological response modifiers
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
US5780225A
(en)
|
1990-01-12 |
1998-07-14 |
Stratagene |
Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
|
|
WO1991010737A1
(en)
|
1990-01-11 |
1991-07-25 |
Molecular Affinities Corporation |
Production of antibodies using gene libraries
|
|
ES2087997T3
(es)
|
1990-01-12 |
1996-08-01 |
Cell Genesys Inc |
Generacion de anticuerpos xenogenicos.
|
|
US5314995A
(en)
|
1990-01-22 |
1994-05-24 |
Oncogen |
Therapeutic interleukin-2-antibody based fusion proteins
|
|
EP0521985B1
(en)
|
1990-03-20 |
1997-09-24 |
The Trustees Of Columbia University In The City Of New York |
Chimeric antibodies with receptor binding ligands in place of their constant region
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
US6172197B1
(en)
|
1991-07-10 |
2001-01-09 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5698426A
(en)
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
|
ES2178635T3
(es)
|
1990-11-09 |
2003-01-01 |
Stephen D Gillies |
Inmunoconjugados de citoquinas.
|
|
DE69129154T2
(de)
|
1990-12-03 |
1998-08-20 |
Genentech, Inc., South San Francisco, Calif. |
Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften
|
|
ATE414768T1
(de)
|
1991-04-10 |
2008-12-15 |
Scripps Research Inst |
Bibliotheken heterodimerer rezeptoren mittels phagemiden
|
|
ATE463573T1
(de)
|
1991-12-02 |
2010-04-15 |
Medimmune Ltd |
Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
WO1995015982A2
(en)
|
1993-12-08 |
1995-06-15 |
Genzyme Corporation |
Process for generating specific antibodies
|
|
DE69531148T2
(de)
|
1994-01-31 |
2004-04-29 |
Trustees Of Boston University, Boston |
Bibliotheken aus polyklonalen antikörpern
|
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
|
DE4440354A1
(de)
|
1994-11-11 |
1996-05-15 |
Hoechst Schering Agrevo Gmbh |
Kombinationen aus Phenylsulfonylharnstoff-Herbiziden und Safenern
|
|
WO1997008320A1
(en)
|
1995-08-18 |
1997-03-06 |
Morphosys Gesellschaft Für Proteinoptimierung Mbh |
Protein/(poly)peptide libraries
|
|
US6828422B1
(en)
|
1995-08-18 |
2004-12-07 |
Morphosys Ag |
Protein/(poly)peptide libraries
|
|
JP2978435B2
(ja)
|
1996-01-24 |
1999-11-15 |
チッソ株式会社 |
アクリロキシプロピルシランの製造方法
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
WO2001002588A2
(en)
|
1999-07-02 |
2001-01-11 |
Morphosys Ag |
Generation of specific binding partners binding to (poly)peptides encoded by genomic dna fragments or ests
|
|
US6849425B1
(en)
|
1999-10-14 |
2005-02-01 |
Ixsys, Inc. |
Methods of optimizing antibody variable region binding affinity
|
|
TWI373343B
(en)
|
2000-02-10 |
2012-10-01 |
Abbott Gmbh & Co Kg |
Antibodies that bind human interleukin-18 and methods of making and using
|
|
US6897067B2
(en)
|
2000-11-03 |
2005-05-24 |
Regents Of The University Of Michigan |
Surface transfection and expression procedure
|
|
JP4368196B2
(ja)
|
2000-11-17 |
2009-11-18 |
ユニバーシティー オブ ロチェスター |
真核細胞において免疫グロブリン分子を製造および同定するインビトロにおける方法
|
|
WO2002096948A2
(en)
|
2001-01-29 |
2002-12-05 |
Idec Pharmaceuticals Corporation |
Engineered tetravalent antibodies and methods of use
|
|
WO2003012061A2
(en)
*
|
2001-08-01 |
2003-02-13 |
Coley Pharmaceutical Gmbh |
Methods and compositions relating to plasmacytoid dendritic cells
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
WO2003081376A2
(en)
|
2002-03-20 |
2003-10-02 |
Catalina Marketing International Inc. |
Targeted incentives based upon predicted behavior
|
|
NZ571508A
(en)
|
2002-05-24 |
2010-05-28 |
Schering Corp |
Neutralizing human anti-IGFR antibody
|
|
WO2004023973A2
(en)
|
2002-09-12 |
2004-03-25 |
Incyte Corporation |
Molecules for diagnostics and therapeutics
|
|
JPWO2005007800A1
(ja)
|
2003-07-18 |
2007-04-12 |
持田製薬株式会社 |
抗血小板膜糖蛋白質ｖｉモノクローナル抗体
|
|
US9208495B2
(en)
|
2003-10-06 |
2015-12-08 |
Yellowpages.Com Llc |
Methods and apparatuses for advertisement presentation
|
|
GB0417487D0
(en)
|
2004-08-05 |
2004-09-08 |
Novartis Ag |
Organic compound
|
|
RU2431638C2
(ru)
*
|
2005-02-10 |
2011-10-20 |
Бэйлор Рисерч Инститьют |
Моноклональные антитела против интерферона-альфа и способы применения
|
|
WO2006124269A2
(en)
*
|
2005-05-16 |
2006-11-23 |
Amgen Fremont Inc. |
Human monoclonal antibodies that bind to very late antigen-1 for the treatment of inflammation and other disorders
|
|
AU2012244391B2
(en)
|
2005-12-20 |
2014-09-11 |
Sbi Biotech Co., Ltd. |
Anti-ILT7 antibody
|
|
MX2008007682A
(es)
|
2005-12-20 |
2008-10-23 |
Sbi Biotech Co Ltd |
Anticuerpo anti-ilt7.
|
|
CN101578297A
(zh)
*
|
2006-04-07 |
2009-11-11 |
美国政府健康及人类服务部 |
治疗肿瘤疾病的抗体组合物和方法
|
|
CN101479375B
(zh)
|
2006-05-03 |
2016-03-30 |
科罗拉多州立大学董事会 |
Cd40激动剂抗体/1型干扰素协同佐剂组合、包含前述的结合物及其作为增强细胞免疫的治疗剂的用途
|
|
US7781306B2
(en)
|
2007-06-20 |
2010-08-24 |
Semiconductor Energy Laboratory Co., Ltd. |
Semiconductor substrate and method for manufacturing the same
|
|
US8092804B2
(en)
|
2007-12-21 |
2012-01-10 |
Medimmune Limited |
Binding members for interleukin-4 receptor alpha (IL-4Rα)-173
|
|
WO2010065536A2
(en)
|
2008-12-01 |
2010-06-10 |
The Board Of Regents Of The University Of Texas System |
Recombinant bone marrow stromal antigen-2 in the treatment of autoimmune diseases
|
|
US20120251546A1
(en)
|
2009-09-03 |
2012-10-04 |
Medimmune Llc |
Type 1 inteferon diagnostic
|
|
EP2496600A1
(en)
|
2009-11-04 |
2012-09-12 |
Fabrus LLC |
Methods for affinity maturation-based antibody optimization
|
|
EP2701742A4
(en)
|
2011-04-26 |
2015-03-18 |
Genentech Inc |
COMPOSITIONS AND METHOD FOR THE TREATMENT OF AUTOIMMUNE DISEASES
|
|
EP3421592B1
(en)
|
2011-04-28 |
2023-09-13 |
The Board of Trustees of the Leland Stanford Junior University |
Identification of polynucleotides associated with a sample
|
|
US9427464B2
(en)
|
2011-11-22 |
2016-08-30 |
Chiome Bioscience Inc. |
Anti-human TROP-2 antibody having an antitumor activity in vivo
|
|
KR102098413B1
(ko)
*
|
2012-01-31 |
2020-04-07 |
에스비아이 바이오테크 가부시키가이샤 |
항-포스포리파아제 ｄ4 항체
|
|
US8605807B1
(en)
|
2012-05-22 |
2013-12-10 |
Nigel Iain Stuart Macrae |
Communicating distinct data over a single frequency using multiple linear polarized signals
|
|
SG11201503637SA
(en)
*
|
2012-11-08 |
2015-06-29 |
Clearside Biomedical Inc |
Methods and devices for the treatment of ocular diseases in human subjects
|
|
US9114438B2
(en)
|
2013-05-21 |
2015-08-25 |
Applied Materials, Inc. |
Copper residue chamber clean
|
|
CN107073096A
(zh)
*
|
2014-08-29 |
2017-08-18 |
索伦托治疗有限公司 |
结合OprF和OprI的抗体治疗
|
|
US11072652B2
(en)
*
|
2016-03-10 |
2021-07-27 |
Viela Bio, Inc. |
ILT7 binding molecules and methods of using the same
|
|
BR112022010786A2
(pt)
|
2019-12-06 |
2022-08-23 |
Viela Bio Inc |
Métodos de tratamento usando proteínas de ligação a ilt7
|
|
US20240287176A1
(en)
|
2021-05-04 |
2024-08-29 |
Viela Bio, Inc. |
Methods of treatment of autoimmune disorders using ilt7 binding proteins
|