JP2019512543A5 - - Google Patents
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- Publication number
- JP2019512543A5 JP2019512543A5 JP2018568165A JP2018568165A JP2019512543A5 JP 2019512543 A5 JP2019512543 A5 JP 2019512543A5 JP 2018568165 A JP2018568165 A JP 2018568165A JP 2018568165 A JP2018568165 A JP 2018568165A JP 2019512543 A5 JP2019512543 A5 JP 2019512543A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- inhibitor molecule
- nucleic acid
- catenin
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021193759A JP7321236B2 (ja) | 2016-03-16 | 2021-11-30 | β－カテニン関連疾患又は障害の治療のための組成物及び方法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662309449P | 2016-03-16 | 2016-03-16 | |
| US62/309,449 | 2016-03-16 | ||
| US201662318529P | 2016-04-05 | 2016-04-05 | |
| US62/318,529 | 2016-04-05 | ||
| US201662365164P | 2016-07-21 | 2016-07-21 | |
| US62/365,164 | 2016-07-21 | ||
| PCT/US2017/022510 WO2017160983A1 (en) | 2016-03-16 | 2017-03-15 | Compositions and methods for the treatment of a beta-catenin-associated disease or disorder |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021193759A Division JP7321236B2 (ja) | 2016-03-16 | 2021-11-30 | β－カテニン関連疾患又は障害の治療のための組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019512543A JP2019512543A (ja) | 2019-05-16 |
| JP2019512543A5 true JP2019512543A5 (https=) | 2019-09-12 |
| JP6987084B2 JP6987084B2 (ja) | 2021-12-22 |
Family
ID=59850959
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018568165A Expired - Fee Related JP6987084B2 (ja) | 2016-03-16 | 2017-03-15 | β−カテニン関連疾患又は障害の治療のための組成物及び方法 |
| JP2021193759A Active JP7321236B2 (ja) | 2016-03-16 | 2021-11-30 | β－カテニン関連疾患又は障害の治療のための組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021193759A Active JP7321236B2 (ja) | 2016-03-16 | 2021-11-30 | β－カテニン関連疾患又は障害の治療のための組成物及び方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US10821112B2 (https=) |
| EP (1) | EP3429598A4 (https=) |
| JP (2) | JP6987084B2 (https=) |
| AU (2) | AU2017232496B2 (https=) |
| CA (1) | CA3017963A1 (https=) |
| WO (1) | WO2017160983A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10821112B2 (en) * | 2016-03-16 | 2020-11-03 | Dicerna Pharmaceuticals, Inc. | Compositions and methods for the treatment of a beta-catenin-associated disease or disorder |
| WO2019079472A1 (en) * | 2017-10-18 | 2019-04-25 | Dicerna Pharmaceuticals, Inc. | BETA-CATENIN NUCLEIC ACID INHIBITOR MOLECULE |
| US11813280B2 (en) | 2018-01-05 | 2023-11-14 | Dicerna Pharmaceuticals, Inc. | Reducing beta-catenin and IDO expression to potentiate immunotherapy |
| WO2020123083A1 (en) * | 2018-12-12 | 2020-06-18 | Dicerna Pharmaceuticals, Inc. | Double-stranded nucleic acid inhibitor molecules containing a triloop |
| AU2020268798A1 (en) * | 2019-05-03 | 2021-11-04 | Dicerna Pharmaceuticals, Inc. | Double-stranded nucleic acid inhibitor molecules with shortened sense strands |
| WO2023122316A2 (en) * | 2021-12-23 | 2023-06-29 | Aligos Therapeutics, Inc. | SPLICE SWITCH OLIGONUCLEOTIDE (SSO) MOLECULES FOR TARGETING β-CATENIN AND USES THEREOF |
| US20250152677A1 (en) * | 2022-02-14 | 2025-05-15 | Institut National de la Santé et de la Recherche Médicale | Treatment of liver cancers by disrupting the beta-catenin/tcf-4 binding site located upstreatm of meg3 in the dlk1/dio3 locus |
| EP4604952A1 (en) * | 2022-10-21 | 2025-08-27 | Recursion Pharmaceuticals, Inc. | Treatment of cancers having mutations in wnt pathway tumour suppressors |
| WO2025147555A1 (en) * | 2024-01-05 | 2025-07-10 | Recursion Pharmaceuticals, Inc. | Rec-4881 (tak-733) for use in treating or preventing colorectal cancer and related diseases |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004535388A (ja) * | 2001-04-30 | 2004-11-25 | ターゲティッド ジェネティクス コーポレイション | 脂質含有薬物送達複合体およびそれらの生成方法 |
| US8198427B1 (en) | 2002-11-14 | 2012-06-12 | Dharmacon, Inc. | SiRNA targeting catenin, beta-1 (CTNNB1) |
| US20100055782A1 (en) * | 2007-03-02 | 2010-03-04 | Mdrna, Inc. | Nucleic acid compounds for inhibiting myc gene expression and uses thereof |
| AU2011276365B2 (en) | 2010-07-06 | 2017-05-11 | Dicerna Pharmaceuticals, Inc. | Methods and compositions for the specific inhibition of beta-catenin by double-stranded RNA |
| EP3330377A1 (en) * | 2010-08-02 | 2018-06-06 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (ctnnb1) gene expression using short interfering nucleic acid (sina) |
| US20150073033A1 (en) | 2011-10-31 | 2015-03-12 | Board Of Regents, The University Of Texas System | Biomarkers for cancer characterization and treatment |
| EP2802658A2 (en) * | 2012-01-09 | 2014-11-19 | Novartis AG | Rnai agents to treat beta-catenin related diseases |
| AU2013315543A1 (en) | 2012-09-14 | 2015-04-09 | Dicerna Pharmaceuticals, Inc. | Methods and compostions for the specific inhibition of MYC by double-stranded RNA |
| EP2917348A1 (en) * | 2012-11-06 | 2015-09-16 | InteRNA Technologies B.V. | Combination for use in treating diseases or conditions associated with melanoma, or treating diseases or conditions associated with activated b-raf pathway |
| CN105163584B (zh) | 2013-03-05 | 2019-06-04 | 田纳西大学研究基金会 | 用于治疗癌症的化合物 |
| CN111053768B (zh) * | 2013-07-12 | 2023-12-12 | 皮拉马尔企业有限公司 | 用于治疗黑素瘤的药物组合 |
| KR102186363B1 (ko) | 2013-09-06 | 2020-12-04 | 삼성전자주식회사 | c-Met 저해제 및 베타-카테닌 저해제를 포함하는 병용 투여용 약학 조성물 |
| KR102192591B1 (ko) * | 2013-09-09 | 2020-12-18 | 삼성전자주식회사 | c-Met 저해제 및 c-Myc 저해제를 포함하는 병용 투여용 약학 조성물 |
| WO2015051252A1 (en) | 2013-10-03 | 2015-04-09 | Duke University | Compositions and methods for treating cancer with jak2 activity |
| US9895312B2 (en) * | 2014-04-08 | 2018-02-20 | Pablo E. Vivas-Mejia | Nanoliposomal c-MYC-siRNA inhibits in vivo tumor growth of cisplatin-resistant ovarian cancer |
| US10821112B2 (en) * | 2016-03-16 | 2020-11-03 | Dicerna Pharmaceuticals, Inc. | Compositions and methods for the treatment of a beta-catenin-associated disease or disorder |
-
2017
- 2017-03-15 US US16/084,852 patent/US10821112B2/en not_active Expired - Fee Related
- 2017-03-15 WO PCT/US2017/022510 patent/WO2017160983A1/en not_active Ceased
- 2017-03-15 AU AU2017232496A patent/AU2017232496B2/en not_active Ceased
- 2017-03-15 EP EP17767430.6A patent/EP3429598A4/en not_active Withdrawn
- 2017-03-15 CA CA3017963A patent/CA3017963A1/en active Pending
- 2017-03-15 JP JP2018568165A patent/JP6987084B2/ja not_active Expired - Fee Related
-
2020
- 2020-09-29 US US17/036,369 patent/US11504374B2/en active Active
-
2021
- 2021-11-30 JP JP2021193759A patent/JP7321236B2/ja active Active
-
2022
- 2022-10-28 US US18/050,760 patent/US20230190753A1/en not_active Abandoned
-
2023
- 2023-02-17 AU AU2023200960A patent/AU2023200960A1/en not_active Abandoned
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