JP2019511567A - 脳卒中と関連する低酸素状態の調節 - Google Patents

脳卒中と関連する低酸素状態の調節 Download PDF

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JP2019511567A
JP2019511567A JP2018561933A JP2018561933A JP2019511567A JP 2019511567 A JP2019511567 A JP 2019511567A JP 2018561933 A JP2018561933 A JP 2018561933A JP 2018561933 A JP2018561933 A JP 2018561933A JP 2019511567 A JP2019511567 A JP 2019511567A
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protein
peg
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covalently linked
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Inventor
レ モアン ナターシャ
レ モアン ナターシャ
クルトリカ アナ
クルトリカ アナ
レオン フィルベルタ
レオン フィルベルタ
ピー．エル． カリー ステファン
ピー．エル． カリー ステファン
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オムニオックス， インコーポレイテッド
オムニオックス， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
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    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
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    • C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01059—Protein geranylgeranyltransferase type I (2.5.1.59)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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JP2018561933A 2016-02-16 2017-02-16 脳卒中と関連する低酸素状態の調節 Pending JP2019511567A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662296009P 2016-02-16 2016-02-16
US62/296,009 2016-02-16
PCT/US2017/018233 WO2017143104A1 (en) 2016-02-16 2017-02-16 Modulation hypoxia associated with stroke

Publications (2)

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JP2019511567A true JP2019511567A (ja) 2019-04-25
JP2019511567A5 JP2019511567A5 (https=) 2020-04-02

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US (3) US20200276265A1 (https=)
EP (1) EP3416673B1 (https=)
JP (1) JP2019511567A (https=)
KR (1) KR20180123034A (https=)
CN (1) CN109069582A (https=)
AU (1) AU2017219869A1 (https=)
BR (1) BR112018016829A2 (https=)
CA (1) CA3014651A1 (https=)
DK (1) DK3416673T3 (https=)
ES (1) ES2939181T3 (https=)
IL (1) IL261178A (https=)
MX (1) MX2018009881A (https=)
RU (1) RU2018131359A (https=)
SG (2) SG11201806920SA (https=)
WO (1) WO2017143104A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2886531T3 (es) * 2013-01-07 2021-12-20 Omniox Inc Formas poliméricas de proteínas H-NOX
EP3836911A1 (en) 2018-08-15 2021-06-23 Omniox, Inc. H-nox proteins for treating cardiovascular and pulmonary conditions
CN118076227A (zh) * 2021-08-18 2024-05-24 欧姆尼奥克斯股份有限公司 用于器官保存的h-nox蛋白

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014107171A1 (en) * 2013-01-07 2014-07-10 Omniox, Inc. Polymeric forms of h-nox proteins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4873192A (en) 1987-02-17 1989-10-10 The United States Of America As Represented By The Department Of Health And Human Services Process for site specific mutagenesis without phenotypic selection
AU735799C (en) 1997-02-28 2005-04-28 Regents Of The University Of California, The Methods and compositions for optimisation of oxygen transport by cell-free systems
JP2005517648A (ja) * 2001-12-07 2005-06-16 インターミューン インコーポレイテッド 肝炎ウイルス感染症を治療するための組成物および方法
US20030153491A1 (en) 2002-01-11 2003-08-14 Winslow Robert M. Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
DK2463297T3 (en) * 2006-05-22 2017-01-09 Univ California Oxygen Compositions and Methods

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014107171A1 (en) * 2013-01-07 2014-07-10 Omniox, Inc. Polymeric forms of h-nox proteins
US20150273024A1 (en) * 2013-01-07 2015-10-01 Omniox, Inc. Biomarkers for h-nox delivery of oxygen

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EP3416673A1 (en) 2018-12-26
SG11201806920SA (en) 2018-09-27
MX2018009881A (es) 2019-01-31
WO2017143104A1 (en) 2017-08-24
WO2017143104A8 (en) 2018-09-07
US20210121521A1 (en) 2021-04-29
CN109069582A (zh) 2018-12-21
ES2939181T3 (es) 2023-04-19
BR112018016829A2 (pt) 2018-12-26
CA3014651A1 (en) 2017-08-24
RU2018131359A3 (https=) 2020-08-12
KR20180123034A (ko) 2018-11-14
RU2018131359A (ru) 2020-03-17
US20240026399A1 (en) 2024-01-25
SG10202007517TA (en) 2020-09-29
IL261178A (en) 2018-10-31
AU2017219869A1 (en) 2018-08-30
US20200276265A1 (en) 2020-09-03
EP3416673B1 (en) 2022-11-02
DK3416673T3 (da) 2023-01-23

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