JP2019511548A5 - - Google Patents
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- JP2019511548A5 JP2019511548A5 JP2018554080A JP2018554080A JP2019511548A5 JP 2019511548 A5 JP2019511548 A5 JP 2019511548A5 JP 2018554080 A JP2018554080 A JP 2018554080A JP 2018554080 A JP2018554080 A JP 2018554080A JP 2019511548 A5 JP2019511548 A5 JP 2019511548A5
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- Prior art keywords
- fluoro
- hydrogen
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- disorders
- disorder
- Prior art date
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- 239000001257 hydrogen Substances 0.000 claims 15
- 125000001153 fluoro group Chemical group F* 0.000 claims 11
- 150000002431 hydrogen Chemical class 0.000 claims 9
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 6
- 125000001309 chloro group Chemical group Cl* 0.000 claims 5
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- CKJNUZNMWOVDFN-UHFFFAOYSA-N methanone Chemical compound O=[CH-] CKJNUZNMWOVDFN-UHFFFAOYSA-N 0.000 description 1
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- 229960002715 nicotine Drugs 0.000 description 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 1
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- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
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- 229960001198 suvorexant Drugs 0.000 description 1
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- 230000002792 vascular Effects 0.000 description 1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16165529.5 | 2016-04-15 | ||
| EP16165529 | 2016-04-15 | ||
| PCT/EP2017/058315 WO2017178340A1 (en) | 2016-04-15 | 2017-04-07 | Novel n-[(pyridyloxy)propanyl]benzamides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019511548A JP2019511548A (ja) | 2019-04-25 |
| JP2019511548A5 true JP2019511548A5 (OSRAM) | 2021-05-20 |
| JP6918827B2 JP6918827B2 (ja) | 2021-08-11 |
Family
ID=55755463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018554080A Active JP6918827B2 (ja) | 2016-04-15 | 2017-04-07 | 新規なｎ−［（ピリジルオキシ）プロパニル］ベンズアミド |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US10787432B2 (OSRAM) |
| EP (1) | EP3442958B1 (OSRAM) |
| JP (1) | JP6918827B2 (OSRAM) |
| WO (1) | WO2017178340A1 (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10604511B2 (en) | 2016-04-15 | 2020-03-31 | Boehringer Ingelheim International Gmbh | N-[(pyrazinyloxy)propanyl]benzamides as antagonists of orexin subtype 1 receptor activity |
| US10710984B2 (en) | 2016-04-15 | 2020-07-14 | Boehringer Ingelheim International Gmbh | N-[(Pyrimidinylamino)propanyl]-and N-[(Pyridinylamino)-propanyl]arylcarboxamides |
| EP3442965B1 (en) | 2016-04-15 | 2021-05-26 | Boehringer Ingelheim International GmbH | Novel n-[(heteroaryloxy)propanyl]heteroaryl carboxamides |
| WO2017178338A1 (en) | 2016-04-15 | 2017-10-19 | Boehringer Ingelheim International Gmbh | Novel n-[(pyrimidinyloxy)propanyl]benzamides |
| JP6591698B2 (ja) * | 2016-04-15 | 2019-10-16 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規なｎ−［（ピリミジニルアミノ）プロパニル］−およびｎ−［（ピラジニルアミノ）プロパニル］アリールカルボキサミド |
| WO2017178340A1 (en) | 2016-04-15 | 2017-10-19 | Boehringer Ingelheim International Gmbh | Novel n-[(pyridyloxy)propanyl]benzamides |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0130341D0 (en) | 2001-12-19 | 2002-02-06 | Smithkline Beecham Plc | Compounds |
| WO2009011775A1 (en) | 2007-07-13 | 2009-01-22 | Merck & Co., Inc. | Amidoethyl alkylamino orexin receptor antagonists |
| SG11201408316SA (en) * | 2012-06-15 | 2015-03-30 | Taisho Pharmaceutical Co Ltd | Branched chain alkyl heteroaromatic ring derivative |
| JP2016028017A (ja) | 2012-12-13 | 2016-02-25 | 大正製薬株式会社 | フッ素置換ピペリジン化合物 |
| JP2017100950A (ja) | 2014-04-04 | 2017-06-08 | 大正製薬株式会社 | オキソ複素環誘導体 |
| GB201415569D0 (en) | 2014-09-03 | 2014-10-15 | C4X Discovery Ltd | Therapeutic Compounds |
| US10604511B2 (en) * | 2016-04-15 | 2020-03-31 | Boehringer Ingelheim International Gmbh | N-[(pyrazinyloxy)propanyl]benzamides as antagonists of orexin subtype 1 receptor activity |
| US10710984B2 (en) | 2016-04-15 | 2020-07-14 | Boehringer Ingelheim International Gmbh | N-[(Pyrimidinylamino)propanyl]-and N-[(Pyridinylamino)-propanyl]arylcarboxamides |
| EP3442965B1 (en) | 2016-04-15 | 2021-05-26 | Boehringer Ingelheim International GmbH | Novel n-[(heteroaryloxy)propanyl]heteroaryl carboxamides |
| WO2017178338A1 (en) | 2016-04-15 | 2017-10-19 | Boehringer Ingelheim International Gmbh | Novel n-[(pyrimidinyloxy)propanyl]benzamides |
| JP6591698B2 (ja) | 2016-04-15 | 2019-10-16 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規なｎ−［（ピリミジニルアミノ）プロパニル］−およびｎ−［（ピラジニルアミノ）プロパニル］アリールカルボキサミド |
| WO2017178340A1 (en) | 2016-04-15 | 2017-10-19 | Boehringer Ingelheim International Gmbh | Novel n-[(pyridyloxy)propanyl]benzamides |
-
2017
- 2017-04-07 WO PCT/EP2017/058315 patent/WO2017178340A1/en not_active Ceased
- 2017-04-07 EP EP17715182.6A patent/EP3442958B1/en active Active
- 2017-04-07 US US16/090,343 patent/US10787432B2/en active Active
- 2017-04-07 JP JP2018554080A patent/JP6918827B2/ja active Active
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