JP2019509976A5 - - Google Patents
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- JP2019509976A5 JP2019509976A5 JP2018528648A JP2018528648A JP2019509976A5 JP 2019509976 A5 JP2019509976 A5 JP 2019509976A5 JP 2018528648 A JP2018528648 A JP 2018528648A JP 2018528648 A JP2018528648 A JP 2018528648A JP 2019509976 A5 JP2019509976 A5 JP 2019509976A5
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021163120A JP7455787B2 (ja) | 2015-12-02 | 2021-10-01 | グリコシル化ｐｄ－１に対して特異的な抗体およびその使用方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562262303P | 2015-12-02 | 2015-12-02 | |
| US62/262,303 | 2015-12-02 | ||
| PCT/US2016/064394 WO2017096026A1 (en) | 2015-12-02 | 2016-12-01 | Antibodies specific to glycosylated pd-1 and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021163120A Division JP7455787B2 (ja) | 2015-12-02 | 2021-10-01 | グリコシル化ｐｄ－１に対して特異的な抗体およびその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019509976A JP2019509976A (ja) | 2019-04-11 |
| JP2019509976A5 true JP2019509976A5 (enExample) | 2020-01-16 |
| JP7003036B2 JP7003036B2 (ja) | 2022-02-04 |
Family
ID=58797717
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018528648A Active JP7003036B2 (ja) | 2015-12-02 | 2016-12-01 | グリコシル化ｐｄ－１に対して特異的な抗体およびその使用方法 |
| JP2021163120A Active JP7455787B2 (ja) | 2015-12-02 | 2021-10-01 | グリコシル化ｐｄ－１に対して特異的な抗体およびその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021163120A Active JP7455787B2 (ja) | 2015-12-02 | 2021-10-01 | グリコシル化ｐｄ－１に対して特異的な抗体およびその使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10858432B2 (enExample) |
| EP (1) | EP3383412A4 (enExample) |
| JP (2) | JP7003036B2 (enExample) |
| KR (1) | KR102809728B1 (enExample) |
| CN (1) | CN109152798B (enExample) |
| WO (1) | WO2017096026A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11933786B2 (en) | 2015-03-30 | 2024-03-19 | Stcube, Inc. | Antibodies specific to glycosylated PD-L1 and methods of use thereof |
| MX383464B (es) | 2015-07-13 | 2025-03-14 | Cytomx Therapeutics Inc | Anticuerpos anti-pd-1, anticuerpos anti-pd-1 activables, y métodos de uso de los mismos. |
| JP6869987B2 (ja) | 2015-09-01 | 2021-05-12 | アジェナス インコーポレイテッド | 抗ｐｄ−１抗体及びその使用方法 |
| MA43028B1 (fr) | 2015-10-02 | 2021-09-30 | Hoffmann La Roche | Anticorps bispécifiques pour pd1 et tim3 |
| CN109152798B (zh) | 2015-12-02 | 2022-10-21 | 斯特库比股份有限公司 | 特异于糖基化的pd-1的抗体及其使用方法 |
| EP3436475A1 (en) | 2016-03-29 | 2019-02-06 | STCube & Co., Inc. | Methods for selecting antibodies that specifically bind glycosylated immune checkpoint proteins |
| US11746152B2 (en) | 2016-07-20 | 2023-09-05 | Stcube, Inc. | Methods of cancer treatment and therapy using a combination of antibodies that bind glycosylated PD-L1 |
| CN110300599B (zh) | 2016-12-07 | 2024-07-02 | 艾吉纳斯公司 | 抗体和其使用方法 |
| EP3568157A4 (en) * | 2017-01-13 | 2021-01-06 | National Research Council of Canada | METHOD FOR OPTIMIZING THE PEPTIDE IMMUNO-EPITOP BY GLYCOSYLATION, OPTIMIZED PEPTIDE THEREOF AND ITS USE FOR CONJUGATE VACCINES |
| KR102461885B1 (ko) | 2017-04-03 | 2022-11-03 | 에프. 호프만-라 로슈 아게 | 항-pd-1 항체와 돌연변이 il-2 또는 il-15의 면역접합체 |
| CA3052532A1 (en) | 2017-04-05 | 2018-10-11 | F. Hoffmann-La Roche Ag | Bispecific antibodies specifically binding to pd1 and lag3 |
| CN111051346A (zh) | 2017-05-31 | 2020-04-21 | 斯特库伯株式会社 | 使用免疫特异性结合btn1a1的抗体和分子治疗癌症的方法 |
| JP2020522562A (ja) | 2017-06-06 | 2020-07-30 | ストキューブ アンド シーオー．， インコーポレイテッド | Ｂｔｎ１ａ１又はｂｔｎ１ａ１リガンドに結合する抗体及び分子を用いて癌を治療する方法 |
| TWI708787B (zh) | 2018-03-02 | 2020-11-01 | 美商美國禮來大藥廠 | Pd-1促效劑抗體及其用途 |
| WO2019195621A1 (en) * | 2018-04-04 | 2019-10-10 | Immutics, Inc. | Methods and compositions for blocking interaction between non-glycosylated pd-1 polypeptides |
| KR20210030366A (ko) | 2018-06-20 | 2021-03-17 | 인사이트 코포레이션 | 항-pd-1 항체 및 이의 용도 |
| CN111166867B (zh) * | 2018-11-09 | 2022-12-20 | 中国科学院分子细胞科学卓越创新中心 | Pd-1泛素化激动剂的功能与用途 |
| CN111423510B (zh) * | 2019-01-10 | 2024-02-06 | 迈威(上海)生物科技股份有限公司 | 重组抗人pd-1抗体及其应用 |
| JP6881658B2 (ja) | 2019-07-05 | 2021-06-02 | 小野薬品工業株式会社 | Ｐｄ−１／ｃｄ３二重特異性タンパク質による血液がん治療 |
| WO2021025140A1 (ja) | 2019-08-08 | 2021-02-11 | 小野薬品工業株式会社 | 二重特異性タンパク質 |
| KR20220088428A (ko) * | 2019-09-26 | 2022-06-27 | 주식회사 에스티큐브앤컴퍼니 | 글리코실화된 ctla-4에 대해 특이적인 항체 및 이의 사용 방법 |
| KR20220088438A (ko) | 2019-10-09 | 2022-06-27 | 주식회사 에스티큐브앤컴퍼니 | 글리코실화된 lag3에 대해 특이적인 항체 및 이의 사용 방법 |
| CN114316022A (zh) * | 2020-09-30 | 2022-04-12 | 正大天晴康方(上海)生物医药科技有限公司 | 结合pd-1抗体的肽及其应用 |
| KR20240005794A (ko) * | 2021-05-18 | 2024-01-12 | 쑤저우 카노바 바이오파마슈티컬 컴퍼니 리미티드 | 항 pd-1 폴리펩티드 및 그의 용도 |
| CN113372447A (zh) * | 2021-05-26 | 2021-09-10 | 重庆中元汇吉生物技术有限公司 | 抗pivka-ii单克隆抗体及其应用 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030148406A1 (en) | 1992-03-17 | 2003-08-07 | David John King | Multivalent antigen-binding proteins |
| ES2367430T3 (es) * | 2002-12-23 | 2011-11-03 | Wyeth Llc | Anticuerpos contra pd-1 y sus usos. |
| DE10303664A1 (de) | 2003-01-23 | 2004-08-12 | Nemod Immuntherapie Ag | Erkennungsmoleküle zur Behandlung und Detektion von Tumoren |
| EP1725585A2 (en) | 2004-03-10 | 2006-11-29 | Lonza Ltd | Method for producing antibodies |
| ES2427147T3 (es) | 2004-06-30 | 2013-10-29 | Mayo Foundation For Medical Education And Research | Anticuerpo sHlgM12 útil para tratar esclerosis múltiple |
| WO2006117910A1 (ja) | 2005-04-28 | 2006-11-09 | Mochida Pharmaceutical Co., Ltd. | 抗血小板膜糖蛋白質ⅵモノクローナル抗体 |
| EP3530736A3 (en) * | 2005-05-09 | 2019-11-06 | ONO Pharmaceutical Co., Ltd. | Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics |
| WO2007124361A2 (en) | 2006-04-20 | 2007-11-01 | Mayo Foundation For Medical Education And Research | Soluble b7-h1 |
| US20080118978A1 (en) | 2006-04-28 | 2008-05-22 | Takashi Sato | Anti-tumor agent |
| PT2170959E (pt) | 2007-06-18 | 2014-01-07 | Merck Sharp & Dohme | Anticorpos para o receptor humano de morte programada pd-1 |
| WO2009089149A1 (en) | 2008-01-03 | 2009-07-16 | The Johns Hopkins University | B7-h1 (cd274) antagonists induce apoptosis of tumor cells |
| WO2010098788A2 (en) * | 2008-08-25 | 2010-09-02 | Amplimmune, Inc. | Pd-i antagonists and methods for treating infectious disease |
| WO2010036959A2 (en) * | 2008-09-26 | 2010-04-01 | Dana-Farber Cancer Institute | Human anti-pd-1, pd-l1, and pd-l2 antibodies and uses therefor |
| EP2198884A1 (en) | 2008-12-18 | 2010-06-23 | Centre National de la Recherche Scientifique (CNRS) | Monoclonal antibodies directed against LG4-5 domain of alpha3 chain of human laminin-5 |
| EP3279215B1 (en) | 2009-11-24 | 2020-02-12 | MedImmune Limited | Targeted binding agents against b7-h1 |
| CA2791648A1 (en) | 2010-03-01 | 2011-09-09 | The J. David Gladstone Institutes | Antibody specific for apolipoprotein and methods of use thereof |
| US9556281B2 (en) | 2011-08-15 | 2017-01-31 | The University Of Chicago | Compositions and methods related to antibodies to staphylococcal protein A |
| EP2755688A4 (en) | 2011-10-27 | 2014-08-06 | Nkt Therapeutics Inc | HUMANIZED ANTIBODIES AGAINST INKT |
| BR112014012819B1 (pt) | 2011-11-28 | 2022-08-16 | Merck Patent Gmbh | Anticorpo anti-pd-l1 ou fragmento de ligação ao antígeno do mesmo e composição |
| CA2874117C (en) * | 2012-07-02 | 2021-10-12 | Kyowa Hakko Kirin Co., Ltd. | Pharmaceutical agent comprising anti-bmp9 antibody as active ingredient for treatment of anemia such as renal anemia and cancer anemia |
| BR112015007672A2 (pt) | 2012-10-04 | 2017-08-08 | Dana Farber Cancer Inst Inc | anticorpos anti-pd-l1 monoclonais humanos e métodos de uso |
| SMT202300039T1 (it) * | 2013-09-13 | 2023-03-17 | Beigene Switzerland Gmbh | Anticorpi anti-pd1 e loro uso come terapia e per diagnostica |
| US10202454B2 (en) | 2013-10-25 | 2019-02-12 | Dana-Farber Cancer Institute, Inc. | Anti-PD-L1 monoclonal antibodies and fragments thereof |
| CR20160319A (es) * | 2013-12-12 | 2016-11-08 | Jiangsu Hengrui Medicine Co | Anticuerpo pd-1, fragmento de union al antigeno de este y uso médico de este |
| ES2763429T5 (es) | 2013-12-17 | 2023-06-21 | Hoffmann La Roche | Procedimientos de tratamiento de cánceres usando antagonistas de la unión al eje de PD-1 y taxanos |
| TWI681969B (zh) * | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對ｐｄ-１的人類抗體 |
| CN103897036B (zh) * | 2014-03-24 | 2016-02-24 | 郑州大学 | 一种pd-1蛋白胞外段亲和肽l8及其应用 |
| TWI595006B (zh) | 2014-12-09 | 2017-08-11 | 禮納特神經系統科學公司 | 抗ｐｄ－１抗體類和使用彼等之方法 |
| EP3277320A4 (en) | 2015-03-30 | 2018-08-01 | Stcube, Inc. | Antibodies specific to glycosylated pd-l1 and methods of use thereof |
| SG10201913304VA (en) | 2015-07-29 | 2020-03-30 | Sharp Kk | Method for device-to-device relay procedure |
| SI3356404T1 (sl) * | 2015-10-02 | 2021-11-30 | F. Hoffmann-La Roche Ag | Protitelesa proti PD1 in postopki uporabe |
| MA43028B1 (fr) * | 2015-10-02 | 2021-09-30 | Hoffmann La Roche | Anticorps bispécifiques pour pd1 et tim3 |
| CN109152798B (zh) | 2015-12-02 | 2022-10-21 | 斯特库比股份有限公司 | 特异于糖基化的pd-1的抗体及其使用方法 |
-
2016
- 2016-12-01 CN CN201680078477.9A patent/CN109152798B/zh active Active
- 2016-12-01 JP JP2018528648A patent/JP7003036B2/ja active Active
- 2016-12-01 WO PCT/US2016/064394 patent/WO2017096026A1/en not_active Ceased
- 2016-12-01 EP EP16871487.1A patent/EP3383412A4/en active Pending
- 2016-12-01 US US15/778,663 patent/US10858432B2/en active Active
- 2016-12-01 KR KR1020187018671A patent/KR102809728B1/ko active Active
-
2020
- 2020-11-13 US US17/097,892 patent/US11981736B2/en active Active
-
2021
- 2021-10-01 JP JP2021163120A patent/JP7455787B2/ja active Active
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