JP2019509046A5 - - Google Patents

Download PDF

Info

Publication number
JP2019509046A5
JP2019509046A5 JP2018548300A JP2018548300A JP2019509046A5 JP 2019509046 A5 JP2019509046 A5 JP 2019509046A5 JP 2018548300 A JP2018548300 A JP 2018548300A JP 2018548300 A JP2018548300 A JP 2018548300A JP 2019509046 A5 JP2019509046 A5 JP 2019509046A5
Authority
JP
Japan
Prior art keywords
antibody
seq
alexa fluor
human
rhodamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018548300A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019509046A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2016/057367 external-priority patent/WO2017093985A1/en
Publication of JP2019509046A publication Critical patent/JP2019509046A/ja
Publication of JP2019509046A5 publication Critical patent/JP2019509046A5/ja
Pending legal-status Critical Current

Links

JP2018548300A 2015-12-05 2016-12-05 Hiv結合剤 Pending JP2019509046A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562263618P 2015-12-05 2015-12-05
US62/263,618 2015-12-05
PCT/IB2016/057367 WO2017093985A1 (en) 2015-12-05 2016-12-05 Hiv binding agents

Publications (2)

Publication Number Publication Date
JP2019509046A JP2019509046A (ja) 2019-04-04
JP2019509046A5 true JP2019509046A5 (enExample) 2020-01-23

Family

ID=57629603

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018548300A Pending JP2019509046A (ja) 2015-12-05 2016-12-05 Hiv結合剤

Country Status (6)

Country Link
US (2) US10730933B2 (enExample)
EP (1) EP3383902A1 (enExample)
JP (1) JP2019509046A (enExample)
CN (1) CN108779168A (enExample)
CA (1) CA3045756A1 (enExample)
WO (1) WO2017093985A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108779168A (zh) 2015-12-05 2018-11-09 沃迪奥斯大学医院中心 Hiv结合剂
WO2020012435A1 (en) * 2018-07-13 2020-01-16 Lausanne University Hospital Hiv binding agents
WO2020082045A1 (en) * 2018-10-19 2020-04-23 University Of Maryland, College Park Multispecfic anti-hiv antibodies
WO2021009697A2 (en) * 2019-07-15 2021-01-21 Lausanne University Hospital Hiv binding agents
CN115963260B (zh) * 2022-06-27 2025-05-23 珠海碳云晶芯智能科技有限公司 多肽芯片及其在艾滋病诊断产品制备中的应用

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DK169582B1 (da) 1986-06-23 1994-12-12 Squibb Bristol Myers Co Humant monoklonalt antistof, der er i stand til at reagere med en epitop på LAV/HTLV-III kappeglycoproteinet gp41, cellelinier, som producerer sådant antistof, farmaceutisk præparat indeholdende antistoffet samt fremgangsmåde til bestemmelse af nærværelsen af LAV/HTLV-III i en biologisk prøve og fremgangsmåde til separering af specifikke antigendeterminanter af LAV/HTLV-III under anvendelse af ant
US5087557A (en) 1986-06-23 1992-02-11 Genetic Systems Corporation Human monoclonal antibody to lymphadenopathy-associated virus
JP3011939B2 (ja) 1987-03-02 2000-02-21 ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ 組換えミコバクテリア・ワクチン
US5504005A (en) 1987-03-02 1996-04-02 Albert Einstein College Of Medicine Of Yeshiva University Recombinant mycobacterial vaccine
DE3855134T2 (de) 1987-11-13 1996-10-02 Hermann Katinger Monoklonale menschliche antikörper gegen hiv-i
US5831034A (en) 1987-11-13 1998-11-03 Hermann Katinger Human monoclonal anti-HIV-I-antibodies
AU608413B2 (en) 1988-03-30 1991-03-28 Abbott Laboratories Mouse monoclonal antibody (5-21-3) to human immunodeficiency virus gp41 protein
US5298419A (en) 1988-03-31 1994-03-29 The Arizona Board Of Regents On Behalf Of The University Of Arizona Human hybridomas and monoclonal antibodies which bind both gp41 and gp120 envelope proteins of human immunodeficiency virus
JPH0292298A (ja) 1988-09-30 1990-04-03 Olympus Optical Co Ltd Hiv構成蛋白に対するモノクローナル抗体
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
WO1990009805A1 (en) 1989-02-28 1990-09-07 New York University Human monoclonal antibodies to human immunodeficiency virus
US5731189A (en) 1989-02-28 1998-03-24 New York University Human monoclonal antibodies to human immunodeficiency virus
AU648505B2 (en) 1989-05-19 1994-04-28 Amgen, Inc. Metalloproteinase inhibitor
US5459060A (en) 1989-08-24 1995-10-17 Bioclonetics Incorporated Human monoclonal antibodies directed against the transmembrane glycoprotein (gp41) of human immunodeficiency virus-1 (HIV-1)
US6008044A (en) 1989-08-24 1999-12-28 Bioclonetics Human monoclonal antibodies directed against the transmembrane glycoprotein (gp41) of human immunodeficiency virus-1 (HIV-1) and detection of antibodies against epitope (GCSGKLIC)
WO1991010742A1 (en) 1990-01-16 1991-07-25 Replgien Corporation Monoclonal antibody specific for non-immunodominant epitope of hiv proteins
WO1991013157A1 (en) 1990-02-26 1991-09-05 Commonwealth Scientific And Industrial Research Organisation Shuttle plasmid for escherichia coli and mycobacteria
GB9015888D0 (en) 1990-07-19 1990-09-05 Smithkline Biolog Vectors
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
AU8507191A (en) 1990-08-29 1992-03-30 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
AU2185592A (en) 1991-06-06 1993-01-08 Med Immune, Inc. Induction of ctl responses to foreign antigens expressed in mycobacteria
DE570357T1 (de) 1992-05-14 1994-07-28 Polimun Scientific Immunbiologische Forschungsgesellschaft Mbh, Wien Peptide, die Antikörper induzieren, die genetisch divergierende HIV-1 Isolationen neutralisieren.
US5652138A (en) 1992-09-30 1997-07-29 The Scripps Research Institute Human neutralizing monoclonal antibodies to human immunodeficiency virus
US6057421A (en) 1994-11-30 2000-05-02 Immpheron, Inc. Variable heavy and light chain regions of murine monoclonal antibody 1F7
CA2218515C (en) 1995-04-19 2008-10-07 Polymun Scientific Immunbiologische Forschung Gmbh Monoclonal antibodies against hiv-1 and vaccines made thereof
MXPA02010374A (es) * 1996-10-10 2003-04-25 Probe Internat Composiciones y metodos para tratar infecciones virales.
JPH10226699A (ja) * 1996-12-10 1998-08-25 Fujirebio Inc Hiv−1グループoを認識するモノクローナル抗体及び該モノクローナル抗体を産生するハイブリドーマ
US20030118985A1 (en) 1997-05-14 2003-06-26 Hunt Jeffrey C. Mouse monoclonal antibody (5-21-3) to human immunodeficiency virus gp41 protein
AU1075001A (en) * 1999-10-05 2001-05-10 Epimmune, Inc. Inducing cellular immune responses to human immunodeficiency virus-1 using peptide and nucleic acid compositions
CN1172717C (zh) 2000-08-18 2004-10-27 清华大学 一种治疗艾滋病的药物及其制备方法
WO2005044474A1 (en) 2003-10-28 2005-05-19 Applied Materials, Inc. Scrubber box and method for using the same
US7744887B2 (en) 2004-06-01 2010-06-29 Merck & Co., Inc. Human antibodies interacting with HIV gp41
EP1807450A2 (en) 2004-10-29 2007-07-18 GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Broadly cross-reactive hiv-1 neutralizing human monoclonal antibodies
AU2010232414A1 (en) * 2009-04-03 2011-10-13 Duke University Mouse models
WO2011046623A2 (en) * 2009-10-16 2011-04-21 Duke University Hiv-1 antibodies
PL3556396T3 (pl) 2010-08-31 2022-09-12 Theraclone Sciences, Inc. Przeciwciała neutralizujące ludzki wirus niedoboru odporności (hiv)
CN104080805B (zh) * 2011-11-07 2017-02-22 美国政府健康及人类服务部 gp41中和性抗体及其用途
WO2015103549A1 (en) 2014-01-03 2015-07-09 The United States Of America, As Represented By The Secretary Department Of Health And Human Services Neutralizing antibodies to hiv-1 env and their use
CN108779168A (zh) 2015-12-05 2018-11-09 沃迪奥斯大学医院中心 Hiv结合剂

Similar Documents

Publication Publication Date Title
JP2017531028A5 (enExample)
JP7406488B2 (ja) 抗体-薬物コンジュゲートの薬物部位を認識する蛋白質
US12275789B2 (en) Human antibodies binding to ROR2
JP2019509046A5 (enExample)
JP2022523200A (ja) 活性化可能な免疫チェックポイント阻害剤とコンジュゲートされた活性化可能な抗体の組み合わせ療法
JP2018520991A (ja) 抗cd71抗体、活性化可能抗cd71抗体、およびその使用方法
JP2018520092A (ja) 抗ITGa3抗体、活性化可能抗ITGa3抗体、およびその使用方法
JP2016503295A5 (enExample)
WO2014144292A2 (en) Antibodies against clostridium difficile toxins and methods of using the same
US20240417446A1 (en) Single domain antibodies targeting the s2 subunit of sars-cov-2 spike protein
JP7711208B2 (ja) Dll3に対する結合分子及びその使用
WO2017093985A4 (en) Hiv binding agents
KR101828794B1 (ko) 중동호흡기증후군 코로나바이러스에 중화활성을 갖는 항체
WO2018138681A1 (en) Hemagglutinin-specific antibodies and uses thereof
CN116568707A (zh) 一种抗体药物偶联物及其医药用途
JP2017531442A (ja) モノクローナル抗gpc−1抗体およびその使用
CN116496389A (zh) 用于治疗hbv感染及相关疾病的表位肽及抗体
WO2023102476A1 (en) Antibodies for coronaviruses and uses thereof
BR112020015475A2 (pt) Molécula ligadora tendo atividade de neutralização contra o coronavírus que causa a síndrome respiratória do oriente médio
US20240425594A1 (en) Novel pd-1 binding domains
EP4410838A1 (en) Anti-cd39 antibody-drug conjugate and use thereof
US20240218055A1 (en) Lassa virus-specific nanobodies and methods of their use
AU2020383580A1 (en) Pharmaceutical combination and use thereof
WO2020233695A1 (zh) 抗乙肝病毒新型抗体及其用途
CN118324916B (zh) 一种抗人gprc5d的单克隆抗体及其制备方法和用途