JP2019508056A5 - - Google Patents

Download PDF

Info

Publication number
JP2019508056A5
JP2019508056A5 JP2018548805A JP2018548805A JP2019508056A5 JP 2019508056 A5 JP2019508056 A5 JP 2019508056A5 JP 2018548805 A JP2018548805 A JP 2018548805A JP 2018548805 A JP2018548805 A JP 2018548805A JP 2019508056 A5 JP2019508056 A5 JP 2019508056A5
Authority
JP
Japan
Prior art keywords
cells
cell
baff
population
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018548805A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019508056A (ja
JP6963560B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/022260 external-priority patent/WO2017160806A1/en
Publication of JP2019508056A publication Critical patent/JP2019508056A/ja
Publication of JP2019508056A5 publication Critical patent/JP2019508056A5/ja
Priority to JP2021169476A priority Critical patent/JP2022023136A/ja
Application granted granted Critical
Publication of JP6963560B2 publication Critical patent/JP6963560B2/ja
Priority to JP2024063798A priority patent/JP2024091728A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018548805A 2016-03-14 2017-03-14 T細胞の拡張及び活性化の方法 Active JP6963560B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2021169476A JP2022023136A (ja) 2016-03-14 2021-10-15 T細胞の拡張及び活性化の方法
JP2024063798A JP2024091728A (ja) 2016-03-14 2024-04-11 T細胞の拡張及び活性化の方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662307989P 2016-03-14 2016-03-14
US62/307,989 2016-03-14
PCT/US2017/022260 WO2017160806A1 (en) 2016-03-14 2017-03-14 Methods of t cell expansion and activation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021169476A Division JP2022023136A (ja) 2016-03-14 2021-10-15 T細胞の拡張及び活性化の方法

Publications (3)

Publication Number Publication Date
JP2019508056A JP2019508056A (ja) 2019-03-28
JP2019508056A5 true JP2019508056A5 (enExample) 2020-04-23
JP6963560B2 JP6963560B2 (ja) 2021-11-10

Family

ID=58461445

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018548805A Active JP6963560B2 (ja) 2016-03-14 2017-03-14 T細胞の拡張及び活性化の方法
JP2021169476A Pending JP2022023136A (ja) 2016-03-14 2021-10-15 T細胞の拡張及び活性化の方法
JP2024063798A Pending JP2024091728A (ja) 2016-03-14 2024-04-11 T細胞の拡張及び活性化の方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2021169476A Pending JP2022023136A (ja) 2016-03-14 2021-10-15 T細胞の拡張及び活性化の方法
JP2024063798A Pending JP2024091728A (ja) 2016-03-14 2024-04-11 T細胞の拡張及び活性化の方法

Country Status (4)

Country Link
US (3) US10563172B2 (enExample)
EP (1) EP3430130B1 (enExample)
JP (3) JP6963560B2 (enExample)
WO (1) WO2017160806A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3430130B1 (en) * 2016-03-14 2023-01-04 Wisconsin Alumni Research Foundation Methods of t cell expansion and activation
JP7557367B2 (ja) * 2017-11-17 2024-09-27 アイオバンス バイオセラピューティクス,インコーポレイテッド 細針吸引及び小生検からのtil拡大培養
WO2025212837A1 (en) * 2024-04-04 2025-10-09 The Regents Of The University Of Michigan Enhanced anti-cancer t-cell therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU779289B2 (en) 2000-05-25 2005-01-13 Xcyte Therapies, Inc. Methods for restoring or enhancing T-cell immune surveillance following naturally or artifically induced immunosuppression
EP1608730B1 (en) * 2003-03-28 2013-11-06 Biogen Idec MA Inc. Truncated baff receptors
PH12013501201A1 (en) * 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
EP3030322A2 (en) 2013-08-05 2016-06-15 Cambridge Enterprise Limited Inhibition of cxcr4 signaling in cancer immunotherapy
EP3097117B1 (en) 2014-01-21 2023-10-04 Novartis Ag Enhanced antigen presenting ability of car t cells by co-introduction of costimulatory molecules
EP3430130B1 (en) * 2016-03-14 2023-01-04 Wisconsin Alumni Research Foundation Methods of t cell expansion and activation

Similar Documents

Publication Publication Date Title
Daher et al. CAR‐NK cells: the next wave of cellular therapy for cancer
Cerwenka et al. Natural killer cell memory in infection, inflammation and cancer
Lee et al. Allogeneic human double negative T cells as a novel immunotherapy for acute myeloid leukemia and its underlying mechanisms
Song et al. IL‐12/IL‐18‐preactivated donor NK cells enhance GVL effects and mitigate GvHD after allogeneic hematopoietic stem cell transplantation
Patel et al. Beyond CAR T cells: other cell-based immunotherapeutic strategies against cancer
JP6899333B2 (ja) 汎用キラーt細胞
Sangiolo Cytokine induced killer cells as promising immunotherapy for solid tumors
JP2016539929A5 (enExample)
Lim et al. GMP-compliant, large-scale expanded allogeneic natural killer cells have potent cytolytic activity against cancer cells in vitro and in vivo
Aftab et al. Toward “off‐the‐shelf” allogeneic CAR T cells
Ghaedrahmati et al. Targeting immune checkpoints: how to use natural killer cells for fighting against solid tumors
CN104411819B (zh) 用于过继细胞疗法的改进的细胞培养方法
JP2020518289A5 (enExample)
Testa et al. CAR-T cell therapy in B-cell acute lymphoblastic leukemia
JP2018522072A5 (enExample)
Smirnov et al. Strategies to circumvent the side-effects of immunotherapy using allogeneic CAR-T cells and boost its efficacy: results of recent clinical trials
Campillo-Davo et al. Efficient and non-genotoxic RNA-based engineering of human T cells using tumor-specific T cell receptors with minimal TCR mispairing
JP2018502114A5 (enExample)
JP2018512047A5 (enExample)
Lizana-Vasquez et al. The application of autologous cancer immunotherapies in the age of memory-NK cells
CN103492406A (zh) 嵌合抗原受体-修饰的t细胞治疗癌症的用途
JP2022023136A5 (enExample)
CN104789595A (zh) 嵌合抗原受体双阴性t细胞的构建方法
Beck et al. Does B cell follicle exclusion of CD8+ T cells make lymph nodes sanctuaries of HIV replication?
JP2018531016A5 (enExample)