JP6963560B2 - T細胞の拡張及び活性化の方法 - Google Patents
T細胞の拡張及び活性化の方法 Download PDFInfo
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- JP6963560B2 JP6963560B2 JP2018548805A JP2018548805A JP6963560B2 JP 6963560 B2 JP6963560 B2 JP 6963560B2 JP 2018548805 A JP2018548805 A JP 2018548805A JP 2018548805 A JP2018548805 A JP 2018548805A JP 6963560 B2 JP6963560 B2 JP 6963560B2
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- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- A61K40/00—Cellular immunotherapy
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- A61K40/31—Chimeric antigen receptors [CAR]
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- A61K40/41—Vertebrate antigens
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/57—Skin; melanoma
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/51—B7 molecules, e.g. CD80, CD86, CD28 (ligand), CD152 (ligand)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/515—CD3, T-cell receptor complex
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
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- C12N2510/00—Genetically modified cells
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- General Chemical & Material Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Dermatology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021169476A JP2022023136A (ja) | 2016-03-14 | 2021-10-15 | T細胞の拡張及び活性化の方法 |
| JP2024063798A JP2024091728A (ja) | 2016-03-14 | 2024-04-11 | T細胞の拡張及び活性化の方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662307989P | 2016-03-14 | 2016-03-14 | |
| US62/307,989 | 2016-03-14 | ||
| PCT/US2017/022260 WO2017160806A1 (en) | 2016-03-14 | 2017-03-14 | Methods of t cell expansion and activation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021169476A Division JP2022023136A (ja) | 2016-03-14 | 2021-10-15 | T細胞の拡張及び活性化の方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019508056A JP2019508056A (ja) | 2019-03-28 |
| JP2019508056A5 JP2019508056A5 (enExample) | 2020-04-23 |
| JP6963560B2 true JP6963560B2 (ja) | 2021-11-10 |
Family
ID=58461445
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018548805A Active JP6963560B2 (ja) | 2016-03-14 | 2017-03-14 | T細胞の拡張及び活性化の方法 |
| JP2021169476A Pending JP2022023136A (ja) | 2016-03-14 | 2021-10-15 | T細胞の拡張及び活性化の方法 |
| JP2024063798A Pending JP2024091728A (ja) | 2016-03-14 | 2024-04-11 | T細胞の拡張及び活性化の方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021169476A Pending JP2022023136A (ja) | 2016-03-14 | 2021-10-15 | T細胞の拡張及び活性化の方法 |
| JP2024063798A Pending JP2024091728A (ja) | 2016-03-14 | 2024-04-11 | T細胞の拡張及び活性化の方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US10563172B2 (enExample) |
| EP (1) | EP3430130B1 (enExample) |
| JP (3) | JP6963560B2 (enExample) |
| CA (1) | CA3017603A1 (enExample) |
| WO (1) | WO2017160806A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6963560B2 (ja) * | 2016-03-14 | 2021-11-10 | ウィスコンシン アラムニ リサーチ ファンデーション | T細胞の拡張及び活性化の方法 |
| KR20200100060A (ko) * | 2017-11-17 | 2020-08-25 | 이오반스 바이오테라퓨틱스, 인크. | 미세 바늘 흡인물 및 소형 생검물로부터의 til 확장 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020019048A1 (en) * | 2000-05-25 | 2002-02-14 | Ronald Berenson | Methods for restoring or enhancing T-cell immune surveillance following naturally or artificially induced immunosuppression |
| AU2004233164B2 (en) * | 2003-03-28 | 2009-10-08 | Biogen Ma Inc. | Truncated BAFF receptors |
| PH12013501201A1 (en) * | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| CA2920377A1 (en) | 2013-08-05 | 2015-02-12 | Cambridge Enterprise Limited | Inhibition of cxcr4 signaling in cancer immunotherapy |
| ES2963718T3 (es) * | 2014-01-21 | 2024-04-01 | Novartis Ag | Capacidad presentadora de antígenos de células CAR-T potenciada mediante introducción conjunta de moléculas co-estimuladoras |
| JP6963560B2 (ja) * | 2016-03-14 | 2021-11-10 | ウィスコンシン アラムニ リサーチ ファンデーション | T細胞の拡張及び活性化の方法 |
-
2017
- 2017-03-14 JP JP2018548805A patent/JP6963560B2/ja active Active
- 2017-03-14 CA CA3017603A patent/CA3017603A1/en active Pending
- 2017-03-14 US US15/458,339 patent/US10563172B2/en active Active
- 2017-03-14 WO PCT/US2017/022260 patent/WO2017160806A1/en not_active Ceased
- 2017-03-14 EP EP17714950.7A patent/EP3430130B1/en active Active
-
2020
- 2020-01-07 US US16/736,389 patent/US12037606B2/en active Active
-
2021
- 2021-10-15 JP JP2021169476A patent/JP2022023136A/ja active Pending
-
2024
- 2024-04-11 JP JP2024063798A patent/JP2024091728A/ja active Pending
- 2024-06-26 US US18/754,949 patent/US20240398695A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2019508056A (ja) | 2019-03-28 |
| US20240398695A1 (en) | 2024-12-05 |
| US20170260506A1 (en) | 2017-09-14 |
| US20200149010A1 (en) | 2020-05-14 |
| WO2017160806A1 (en) | 2017-09-21 |
| JP2024091728A (ja) | 2024-07-05 |
| EP3430130A1 (en) | 2019-01-23 |
| JP2022023136A (ja) | 2022-02-07 |
| CA3017603A1 (en) | 2017-09-21 |
| US10563172B2 (en) | 2020-02-18 |
| US12037606B2 (en) | 2024-07-16 |
| EP3430130B1 (en) | 2023-01-04 |
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