JP2019508036A5 - - Google Patents
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- JP2019508036A5 JP2019508036A5 JP2018542777A JP2018542777A JP2019508036A5 JP 2019508036 A5 JP2019508036 A5 JP 2019508036A5 JP 2018542777 A JP2018542777 A JP 2018542777A JP 2018542777 A JP2018542777 A JP 2018542777A JP 2019508036 A5 JP2019508036 A5 JP 2019508036A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- domain
- binding molecule
- recognition
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662295867P | 2016-02-16 | 2016-02-16 | |
| US62/295,867 | 2016-02-16 | ||
| PCT/US2017/018216 WO2017143094A1 (en) | 2016-02-16 | 2017-02-16 | Immunotherapy compositions and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019508036A JP2019508036A (ja) | 2019-03-28 |
| JP2019508036A5 true JP2019508036A5 (https=) | 2020-03-26 |
Family
ID=58231709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018542777A Ceased JP2019508036A (ja) | 2016-02-16 | 2017-02-16 | 免疫療法組成物及び方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11225520B2 (https=) |
| EP (1) | EP3416686A1 (https=) |
| JP (1) | JP2019508036A (https=) |
| CN (1) | CN108697798A (https=) |
| AU (2) | AU2017219859A1 (https=) |
| CA (1) | CA3013479A1 (https=) |
| WO (1) | WO2017143094A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| JP7282521B2 (ja) | 2016-04-08 | 2023-05-29 | パーデュー・リサーチ・ファウンデイション | Ｃａｒ ｔ細胞療法のための方法および組成物 |
| CN110612119B (zh) | 2017-02-07 | 2024-10-29 | 西雅图儿童医院（Dba西雅图儿童研究所） | 磷脂醚(ple)car t细胞肿瘤靶向(ctct)剂 |
| JP7178355B2 (ja) | 2017-02-28 | 2022-11-25 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための組成物および方法 |
| WO2019060425A1 (en) | 2017-09-19 | 2019-03-28 | Massachusetts Institute Of Technology | COMPOSITIONS FOR CHIMERIC ANTIGENIC RECEPTOR T CELL THERAPY AND USES THEREOF |
| CN109553686A (zh) * | 2017-09-26 | 2019-04-02 | 南京安吉生物科技有限公司 | 一种新型可调控的双嵌合抗原受体t细胞及其构建方法和应用 |
| US20200385440A1 (en) * | 2017-12-07 | 2020-12-10 | Janux Therapeutics, Inc. | Modified bispecific t cell receptors |
| US20200338128A1 (en) * | 2018-01-05 | 2020-10-29 | Gencyte Therapeutics, Inc. | Precision molecular adaptor system for car-t immunotherapy |
| ES2960686T3 (es) | 2018-01-19 | 2024-03-06 | Miltenyi Biotec Bv & Co Kg | Células T reguladoras que expresan un receptor de antígeno quimérico |
| JP7549303B2 (ja) | 2018-01-22 | 2024-09-11 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞の使用方法 |
| SG11202007426XA (en) * | 2018-02-06 | 2020-09-29 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors |
| CN112105382A (zh) | 2018-02-23 | 2020-12-18 | 恩多塞特公司 | 用于car t细胞疗法的顺序方法 |
| US20210145881A1 (en) * | 2018-04-09 | 2021-05-20 | Mayo Foundation For Medical Education And Research | Methods and materials for treating graft-versus-host disease |
| WO2019240934A1 (en) * | 2018-06-12 | 2019-12-19 | Promab Biotechnologies, Inc. | Plap-car-effector cells |
| AU2019291882A1 (en) | 2018-06-28 | 2020-11-26 | Dana-Farber Cancer Institute, Inc. | Targeting of multiple antigens with multiplex CAR T cells in solid and liquid malignancies |
| EP3856763A1 (en) | 2018-09-28 | 2021-08-04 | Massachusetts Institute of Technology | Collagen-localized immunomodulatory molecules and methods thereof |
| US12264189B2 (en) | 2018-10-31 | 2025-04-01 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
| WO2020092736A1 (en) | 2018-10-31 | 2020-05-07 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
| WO2020102503A2 (en) | 2018-11-14 | 2020-05-22 | Flagship Pioneering Innovations V, Inc. | Fusosome compositions for t cell delivery |
| JPWO2020246563A1 (https=) * | 2019-06-05 | 2020-12-10 | ||
| JP2022538974A (ja) | 2019-06-26 | 2022-09-07 | マサチューセッツ インスチテュート オブ テクノロジー | 免疫調節融合タンパク質－金属水酸化物錯体およびその方法 |
| WO2021061648A1 (en) | 2019-09-23 | 2021-04-01 | Massachusetts Institute Of Technology | Methods and compositions for stimulation of endogenous t cell responses |
| BR112022012112A2 (pt) | 2019-12-20 | 2022-09-06 | Regeneron Pharma | Agonistas de il2 e métodos de uso dos mesmos |
| AU2021217003A1 (en) | 2020-02-04 | 2022-09-15 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Anti-dinitrophenol chimeric antigen receptors |
| BR112022019841A2 (pt) | 2020-04-09 | 2022-12-06 | Cytomx Therapeutics Inc | Composições contendo anticorpos ativáveis |
| EP4232079A4 (en) * | 2020-10-20 | 2024-10-23 | The Board Of Trustees Of The Leland Stanford Junior University | INJECTABLE HYDROGELS FOR ADOPTIVE CELL THERAPY |
| TW202317623A (zh) | 2021-06-14 | 2023-05-01 | 美商再生元醫藥公司 | 基於il2之治療劑及其使用方法 |
| WO2024097992A2 (en) | 2022-11-04 | 2024-05-10 | Umoja Biopharma, Inc. | Particles displaying adhesion-molecule fusions |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946929A (en) | 1983-03-22 | 1990-08-07 | Massachusetts Institute Of Technology | Bioerodible articles useful as implants and prostheses having predictable degradation rates |
| US4638045A (en) | 1985-02-19 | 1987-01-20 | Massachusetts Institute Of Technology | Non-peptide polyamino acid bioerodible polymers |
| US4797368A (en) | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| US4806621A (en) | 1986-01-21 | 1989-02-21 | Massachusetts Institute Of Technology | Biocompatible, bioerodible, hydrophobic, implantable polyimino carbonate article |
| US5736372A (en) | 1986-11-20 | 1998-04-07 | Massachusetts Institute Of Technology | Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure |
| CA1340581C (en) | 1986-11-20 | 1999-06-08 | Joseph P. Vacanti | Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices |
| US5759830A (en) | 1986-11-20 | 1998-06-02 | Massachusetts Institute Of Technology | Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo |
| US5019379A (en) | 1987-07-31 | 1991-05-28 | Massachusetts Institute Of Technology | Unsaturated polyanhydrides |
| US5010167A (en) | 1989-03-31 | 1991-04-23 | Massachusetts Institute Of Technology | Poly(amide-and imide-co-anhydride) for biological application |
| US5399665A (en) | 1992-11-05 | 1995-03-21 | Massachusetts Institute Of Technology | Biodegradable polymers for cell transplantation |
| US5512600A (en) | 1993-01-15 | 1996-04-30 | Massachusetts Institute Of Technology | Preparation of bonded fiber structures for cell implantation |
| US5514378A (en) | 1993-02-01 | 1996-05-07 | Massachusetts Institute Of Technology | Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures |
| US5716404A (en) | 1994-12-16 | 1998-02-10 | Massachusetts Institute Of Technology | Breast tissue engineering |
| US6123727A (en) | 1995-05-01 | 2000-09-26 | Massachusetts Institute Of Technology | Tissue engineered tendons and ligaments |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| US6095148A (en) | 1995-11-03 | 2000-08-01 | Children's Medical Center Corporation | Neuronal stimulation using electrically conducting polymers |
| US5902599A (en) | 1996-02-20 | 1999-05-11 | Massachusetts Institute Of Technology | Biodegradable polymer networks for use in orthopedic and dental applications |
| US5928906A (en) | 1996-05-09 | 1999-07-27 | Sequenom, Inc. | Process for direct sequencing during template amplification |
| US5837752A (en) | 1997-07-17 | 1998-11-17 | Massachusetts Institute Of Technology | Semi-interpenetrating polymer networks |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| US9193791B2 (en) * | 2010-08-03 | 2015-11-24 | City Of Hope | Development of masked therapeutic antibodies to limit off-target effects |
| KR101765364B1 (ko) | 2010-11-26 | 2017-08-08 | 에보니크 룀 게엠베하 | 항원 차폐제로서의 사용을 위한 인간 락토페린 유래 펩티드 |
| ES2791716T3 (es) * | 2010-12-14 | 2020-11-05 | Univ Maryland | Células T que expresan al receptor de antígeno quimérico antietiqueta universal y métodos para el tratamiento del cáncer |
| WO2012177775A1 (en) | 2011-06-20 | 2012-12-27 | Akrivis Technologies, Llc | Reagents and methods for bispecific antibody-based binding of target molecules |
| GB201203442D0 (en) * | 2012-02-28 | 2012-04-11 | Univ Birmingham | Immunotherapeutic molecules and uses |
| CN104540518A (zh) * | 2012-04-27 | 2015-04-22 | 西托姆克斯治疗公司 | 结合表皮生长因子受体的可活化的抗体其使用方法 |
| EP2935337A4 (en) | 2012-12-20 | 2016-10-05 | Akrivis Technologies Llc | POLYMERS CONTAINING A MIXED USEFUL LOAD AND THEIR USE |
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| EP3057991B8 (en) | 2013-10-15 | 2019-09-04 | The Scripps Research Institute | Chimeric antigen receptor t cell switches and uses thereof |
| IL270562B (en) | 2014-01-31 | 2022-08-01 | Cytomx Therapeutics Inc | Polypeptide substrates that activate matriptase and u-plasminogen and other cleavable groups, preparations containing them and their uses |
| MY167722A (en) | 2014-10-09 | 2018-09-21 | Univ Yamaguchi | Car expression vector and car-expressing t cells |
| WO2016154621A1 (en) | 2015-03-26 | 2016-09-29 | The California Institute For Biomedical Research | SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF |
| WO2016168769A1 (en) | 2015-04-15 | 2016-10-20 | The California Institute For Biomedical Research | Chimeric receptor t cell switches for her2 |
| WO2017112877A1 (en) | 2015-12-22 | 2017-06-29 | Icell Gene Therapeutics, Llc | Chimeric antigen receptors and enhancement of anti-tumor activity |
| CN105504042A (zh) | 2016-02-04 | 2016-04-20 | 北京艺妙神州医疗科技有限公司 | 检测car-t细胞的捕获探针、该细胞含量的检测方法及应用 |
| US20170274095A1 (en) | 2016-03-23 | 2017-09-28 | The Board Of Trustees Of The Leland Stanford Junior University | Enhanced regulatory t cells targeted to sites of inflammation with chimeric antigen receptors and expressing factors that enhance viability of pancreatic cells |
| JP7282521B2 (ja) | 2016-04-08 | 2023-05-29 | パーデュー・リサーチ・ファウンデイション | Ｃａｒ ｔ細胞療法のための方法および組成物 |
| CN110267982B (zh) | 2016-10-19 | 2024-02-23 | 斯克利普斯研究所 | 具有人源化靶向部分和/或经过优化的嵌合抗原受体相互作用结构域的嵌合抗原受体效应细胞开关以及其用途 |
| CN110662839A (zh) | 2017-02-17 | 2020-01-07 | 珀杜研究基金会 | 用于细胞疗法的基于靶向性配体-有效负载的药物递送 |
| JP7178355B2 (ja) | 2017-02-28 | 2022-11-25 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための組成物および方法 |
| CN108490174B (zh) | 2018-04-18 | 2022-06-24 | 上海尚珞生物医药科技有限公司 | 检测car-t细胞的方法及其应用 |
| CN108660113A (zh) | 2018-05-21 | 2018-10-16 | 杭州启澜生物医学技术有限公司 | 一种制备改良型car-t细胞的方法 |
-
2017
- 2017-02-16 JP JP2018542777A patent/JP2019508036A/ja not_active Ceased
- 2017-02-16 CA CA3013479A patent/CA3013479A1/en active Pending
- 2017-02-16 US US16/077,939 patent/US11225520B2/en active Active
- 2017-02-16 AU AU2017219859A patent/AU2017219859A1/en not_active Abandoned
- 2017-02-16 WO PCT/US2017/018216 patent/WO2017143094A1/en not_active Ceased
- 2017-02-16 CN CN201780011853.7A patent/CN108697798A/zh active Pending
- 2017-02-16 EP EP17709233.5A patent/EP3416686A1/en active Pending
-
2024
- 2024-04-24 AU AU2024202680A patent/AU2024202680A1/en active Pending
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