JP2019506882A5 - - Google Patents
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- Publication number
- JP2019506882A5 JP2019506882A5 JP2018545660A JP2018545660A JP2019506882A5 JP 2019506882 A5 JP2019506882 A5 JP 2019506882A5 JP 2018545660 A JP2018545660 A JP 2018545660A JP 2018545660 A JP2018545660 A JP 2018545660A JP 2019506882 A5 JP2019506882 A5 JP 2019506882A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nucleic acid
- acid molecule
- polynucleotide
- nucleotide sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108091033319 polynucleotide Proteins 0.000 claims 19
- 102000040430 polynucleotide Human genes 0.000 claims 19
- 239000002157 polynucleotide Substances 0.000 claims 19
- 102000039446 nucleic acids Human genes 0.000 claims 18
- 108020004707 nucleic acids Proteins 0.000 claims 18
- 150000007523 nucleic acids Chemical class 0.000 claims 18
- 239000002773 nucleotide Substances 0.000 claims 14
- 125000003729 nucleotide group Chemical group 0.000 claims 14
- 239000013604 expression vector Substances 0.000 claims 7
- 210000004962 mammalian cell Anatomy 0.000 claims 5
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 4
- 239000013598 vector Substances 0.000 claims 4
- 230000001737 promoting effect Effects 0.000 claims 3
- 230000035897 transcription Effects 0.000 claims 3
- 238000013518 transcription Methods 0.000 claims 3
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 239000013612 plasmid Substances 0.000 claims 2
- 241000282693 Cercopithecidae Species 0.000 claims 1
- 241000699800 Cricetinae Species 0.000 claims 1
- 241000713666 Lentivirus Species 0.000 claims 1
- 241000699666 Mus <mouse, genus> Species 0.000 claims 1
- 241000700159 Rattus Species 0.000 claims 1
- 241000700618 Vaccinia virus Species 0.000 claims 1
- 206010046865 Vaccinia virus infection Diseases 0.000 claims 1
- 210000005260 human cell Anatomy 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000013600 plasmid vector Substances 0.000 claims 1
- 108091008146 restriction endonucleases Proteins 0.000 claims 1
- 238000001890 transfection Methods 0.000 claims 1
- 241000701161 unidentified adenovirus Species 0.000 claims 1
- 241000701447 unidentified baculovirus Species 0.000 claims 1
- 241001430294 unidentified retrovirus Species 0.000 claims 1
- 208000007089 vaccinia Diseases 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1603577.6 | 2016-03-01 | ||
| GBGB1603577.6A GB201603577D0 (en) | 2016-03-01 | 2016-03-01 | Promoter |
| PCT/GB2017/050537 WO2017149292A1 (en) | 2016-03-01 | 2017-02-28 | Promoter |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019506882A JP2019506882A (ja) | 2019-03-14 |
| JP2019506882A5 true JP2019506882A5 (enExample) | 2020-04-09 |
| JP6960409B2 JP6960409B2 (ja) | 2021-11-05 |
Family
ID=55807149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018545660A Active JP6960409B2 (ja) | 2016-03-01 | 2017-02-28 | プロモーター |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10647999B2 (enExample) |
| EP (2) | EP3423583B1 (enExample) |
| JP (1) | JP6960409B2 (enExample) |
| KR (1) | KR102755545B1 (enExample) |
| CN (1) | CN109072251A (enExample) |
| AU (1) | AU2017225350B2 (enExample) |
| GB (3) | GB201603577D0 (enExample) |
| SG (1) | SG11201806782QA (enExample) |
| WO (1) | WO2017149292A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110892064A (zh) | 2017-07-25 | 2020-03-17 | 牛津遗传学有限公司 | 腺病毒载体 |
| CN107630035A (zh) * | 2017-09-28 | 2018-01-26 | 兰州大学 | 一种大鼠防御素真核表达载体及其构建方法 |
| GB201800903D0 (en) | 2018-01-19 | 2018-03-07 | Oxford Genetics Ltd | Vectors |
| BR112020015798A2 (pt) | 2018-02-01 | 2021-03-09 | Homology Medicines, Inc. | Composições de vírus adeno-associado para restaurar função de gene da pah e métodos de uso das mesmas |
| GB201901571D0 (en) | 2019-02-05 | 2019-03-27 | Oxford Genetics Ltd | Inducible AAV sysyem |
| TW202208632A (zh) | 2020-05-27 | 2022-03-01 | 美商同源醫藥公司 | 用於恢復ｐａｈ基因功能的腺相關病毒組成物及其使用方法 |
| AU2022373653A1 (en) | 2021-10-18 | 2024-05-02 | Regeneron Pharmaceuticals, Inc. | Eukaryotic cells comprising adenovirus-associated virus polynucleotides |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007081336A1 (en) * | 2006-01-13 | 2007-07-19 | Five Prime Therapeutics, Inc. | Mammalian vectors for high-level expression of recombinant proteins |
| EA014757B1 (ru) * | 2006-02-28 | 2011-02-28 | Вэксарт, Инк. | Химерный аденовирусный вектор, иммуногенная композиция на его основе, способ индукции иммуного ответа с его помощью и выделенная нуклеиновая кислота |
| US9388425B2 (en) * | 2006-10-20 | 2016-07-12 | Trustees Of Boston University | Tunable genetic switch for regulating gene expression |
| EP2097538A4 (en) * | 2006-12-07 | 2011-11-30 | Switchgear Genomics | TRANSCRIPTION REAGULATION ELEMENTS OF BIOLOGICAL PATHS, TOOLS AND METHODS |
| DK2477652T3 (en) * | 2009-09-16 | 2015-07-20 | Vaxart Inc | Immunization strategy for the prevention of infection H1Ni |
| EP2611915B1 (en) * | 2010-09-01 | 2015-04-15 | Cellagenics B.V. | Nucleic acid fragments from a ribosomal protein promoter for enhancing gene expression |
| WO2012112603A1 (en) | 2011-02-14 | 2012-08-23 | University Of Utah Research Foundations | Constructs and methods for generating induced pluri potent stem ( ips) cells |
| AU2012238601B2 (en) | 2011-04-07 | 2017-01-12 | Bayer Cropscience Nv | Seed - specific promoter in cotton |
| US9234197B2 (en) * | 2011-10-28 | 2016-01-12 | Arizona Board Of Regents, A Body Corporate Of The State Of Arizona For And On Behalf Of Arizona State University | Genetic element that enhances protein translation |
| DK2711426T3 (en) * | 2012-09-24 | 2015-07-13 | Lonza Biologics Plc | Expression vectors comprising chimeric cytomegalovirus promoter and enhancer sequences |
| DK2971005T3 (da) | 2013-03-12 | 2020-08-24 | Agc Biologics Inc | Forbedret rekombinant proteinekspression ved anvendelse af en hybrid CHEF1-promotor |
| CN104630267B (zh) * | 2014-07-17 | 2017-10-31 | 清华大学 | 利用tale转录抑制子在哺乳动物细胞中模块化构建合成基因线路的试剂盒 |
| GB201414130D0 (en) * | 2014-08-08 | 2014-09-24 | Agency Science Tech & Res | Mutants of the bacteriophage lambda integrase |
-
2016
- 2016-03-01 GB GBGB1603577.6A patent/GB201603577D0/en not_active Ceased
-
2017
- 2017-02-28 GB GB2002193.7A patent/GB2578859B/en not_active Expired - Fee Related
- 2017-02-28 AU AU2017225350A patent/AU2017225350B2/en active Active
- 2017-02-28 WO PCT/GB2017/050537 patent/WO2017149292A1/en not_active Ceased
- 2017-02-28 EP EP17712536.6A patent/EP3423583B1/en active Active
- 2017-02-28 CN CN201780014321.9A patent/CN109072251A/zh active Pending
- 2017-02-28 SG SG11201806782QA patent/SG11201806782QA/en unknown
- 2017-02-28 JP JP2018545660A patent/JP6960409B2/ja active Active
- 2017-02-28 KR KR1020187024944A patent/KR102755545B1/ko active Active
- 2017-02-28 US US16/080,765 patent/US10647999B2/en active Active
- 2017-02-28 GB GB1703224.4A patent/GB2553170B/en not_active Expired - Fee Related
- 2017-02-28 EP EP20157991.9A patent/EP3686282B1/en active Active
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