JP2019506882A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019506882A5 JP2019506882A5 JP2018545660A JP2018545660A JP2019506882A5 JP 2019506882 A5 JP2019506882 A5 JP 2019506882A5 JP 2018545660 A JP2018545660 A JP 2018545660A JP 2018545660 A JP2018545660 A JP 2018545660A JP 2019506882 A5 JP2019506882 A5 JP 2019506882A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nucleic acid
- acid molecule
- polynucleotide
- nucleotide sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108091033319 polynucleotide Proteins 0.000 claims 19
- 102000040430 polynucleotide Human genes 0.000 claims 19
- 239000002157 polynucleotide Substances 0.000 claims 19
- 102000039446 nucleic acids Human genes 0.000 claims 18
- 108020004707 nucleic acids Proteins 0.000 claims 18
- 150000007523 nucleic acids Chemical class 0.000 claims 18
- 239000002773 nucleotide Substances 0.000 claims 14
- 125000003729 nucleotide group Chemical group 0.000 claims 14
- 239000013604 expression vector Substances 0.000 claims 7
- 210000004962 mammalian cell Anatomy 0.000 claims 5
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 4
- 239000013598 vector Substances 0.000 claims 4
- 230000001737 promoting effect Effects 0.000 claims 3
- 230000035897 transcription Effects 0.000 claims 3
- 238000013518 transcription Methods 0.000 claims 3
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 239000013612 plasmid Substances 0.000 claims 2
- 241000282693 Cercopithecidae Species 0.000 claims 1
- 241000699800 Cricetinae Species 0.000 claims 1
- 241000713666 Lentivirus Species 0.000 claims 1
- 241000699666 Mus <mouse, genus> Species 0.000 claims 1
- 241000700159 Rattus Species 0.000 claims 1
- 241000700618 Vaccinia virus Species 0.000 claims 1
- 206010046865 Vaccinia virus infection Diseases 0.000 claims 1
- 210000005260 human cell Anatomy 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000013600 plasmid vector Substances 0.000 claims 1
- 108091008146 restriction endonucleases Proteins 0.000 claims 1
- 238000001890 transfection Methods 0.000 claims 1
- 241000701161 unidentified adenovirus Species 0.000 claims 1
- 241000701447 unidentified baculovirus Species 0.000 claims 1
- 241001430294 unidentified retrovirus Species 0.000 claims 1
- 208000007089 vaccinia Diseases 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1603577.6A GB201603577D0 (en) | 2016-03-01 | 2016-03-01 | Promoter |
| GB1603577.6 | 2016-03-01 | ||
| PCT/GB2017/050537 WO2017149292A1 (en) | 2016-03-01 | 2017-02-28 | Promoter |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019506882A JP2019506882A (ja) | 2019-03-14 |
| JP2019506882A5 true JP2019506882A5 (enExample) | 2020-04-09 |
| JP6960409B2 JP6960409B2 (ja) | 2021-11-05 |
Family
ID=55807149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018545660A Active JP6960409B2 (ja) | 2016-03-01 | 2017-02-28 | プロモーター |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10647999B2 (enExample) |
| EP (2) | EP3686282B1 (enExample) |
| JP (1) | JP6960409B2 (enExample) |
| KR (1) | KR102755545B1 (enExample) |
| AU (1) | AU2017225350B2 (enExample) |
| GB (3) | GB201603577D0 (enExample) |
| SG (1) | SG11201806782QA (enExample) |
| WO (1) | WO2017149292A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110892064A (zh) | 2017-07-25 | 2020-03-17 | 牛津遗传学有限公司 | 腺病毒载体 |
| CN107630035A (zh) * | 2017-09-28 | 2018-01-26 | 兰州大学 | 一种大鼠防御素真核表达载体及其构建方法 |
| GB201800903D0 (en) | 2018-01-19 | 2018-03-07 | Oxford Genetics Ltd | Vectors |
| AU2019215152A1 (en) * | 2018-02-01 | 2020-08-20 | Homology Medicines, Inc. | Adeno-associated virus compositions for restoring PAH gene function and methods of use thereof |
| GB201901571D0 (en) | 2019-02-05 | 2019-03-27 | Oxford Genetics Ltd | Inducible AAV sysyem |
| TW202208632A (zh) | 2020-05-27 | 2022-03-01 | 美商同源醫藥公司 | 用於恢復ｐａｈ基因功能的腺相關病毒組成物及其使用方法 |
| JP2024537896A (ja) | 2021-10-18 | 2024-10-16 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | アデノウイルス随伴ウイルスポリヌクレオチドを含む真核細胞 |
| AR127674A1 (es) | 2021-10-18 | 2024-02-21 | Regeneron Pharma | Células de mamífero que comprenden genes cas9 integrados para producir sitios de integración estables, y células de mamífero que comprenden sitios de integración estables y otros sitios |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007081336A1 (en) * | 2006-01-13 | 2007-07-19 | Five Prime Therapeutics, Inc. | Mammalian vectors for high-level expression of recombinant proteins |
| PT1996238T (pt) * | 2006-02-28 | 2016-07-11 | Vaxart Inc | Vetores adenovíricos quiméricos e arncd como agonista de tlr3 |
| WO2008051854A2 (en) * | 2006-10-20 | 2008-05-02 | Trustees Of Boston University | A tunable genetic switch for regulating gene expression |
| EP2097538A4 (en) | 2006-12-07 | 2011-11-30 | Switchgear Genomics | TRANSCRIPTION REAGULATION ELEMENTS OF BIOLOGICAL PATHS, TOOLS AND METHODS |
| WO2011034950A1 (en) * | 2009-09-16 | 2011-03-24 | Vaxart, Inc. | Immunization strategy to prevent h1n1 infection |
| WO2012112603A1 (en) * | 2011-02-14 | 2012-08-23 | University Of Utah Research Foundations | Constructs and methods for generating induced pluri potent stem ( ips) cells |
| BR112013025819A2 (pt) | 2011-04-07 | 2016-12-20 | Bayer Crospscience N V | promotor específico para semente em algodão |
| EP2771465A1 (en) * | 2011-10-28 | 2014-09-03 | Arizona Board of Regents, a Body Corporate of the State of Arizona acting for and on behalf of Arizona State University | Genetic element that enhances protein translation |
| HUE026516T2 (en) * | 2012-09-24 | 2016-06-28 | Lonza Biologics Plc | Expression vectors containing chimeric cytomegalovirus promoter and enhancer sequences |
| EP3770263A1 (en) | 2013-03-12 | 2021-01-27 | AGC Biologics, Inc. | Improved recombinant protein expression using a hybrid chef1 promoter |
| CN104630267B (zh) * | 2014-07-17 | 2017-10-31 | 清华大学 | 利用tale转录抑制子在哺乳动物细胞中模块化构建合成基因线路的试剂盒 |
| GB201414130D0 (en) * | 2014-08-08 | 2014-09-24 | Agency Science Tech & Res | Mutants of the bacteriophage lambda integrase |
-
2016
- 2016-03-01 GB GBGB1603577.6A patent/GB201603577D0/en not_active Ceased
-
2017
- 2017-02-28 KR KR1020187024944A patent/KR102755545B1/ko active Active
- 2017-02-28 EP EP20157991.9A patent/EP3686282B1/en active Active
- 2017-02-28 US US16/080,765 patent/US10647999B2/en active Active
- 2017-02-28 WO PCT/GB2017/050537 patent/WO2017149292A1/en not_active Ceased
- 2017-02-28 GB GB1703224.4A patent/GB2553170B/en not_active Expired - Fee Related
- 2017-02-28 GB GB2002193.7A patent/GB2578859B/en not_active Expired - Fee Related
- 2017-02-28 JP JP2018545660A patent/JP6960409B2/ja active Active
- 2017-02-28 SG SG11201806782QA patent/SG11201806782QA/en unknown
- 2017-02-28 EP EP17712536.6A patent/EP3423583B1/en active Active
- 2017-02-28 AU AU2017225350A patent/AU2017225350B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019196400A5 (enExample) | ||
| Zheng et al. | Massively parallel in vivo Perturb-seq reveals cell-type-specific transcriptional networks in cortical development | |
| Kajikawa et al. | LINEs mobilize SINEs in the eel through a shared 3′ sequence | |
| Medstrand et al. | Expression of human endogenous retroviral sequences in peripheral blood mononuclear cells of healthy individuals | |
| Ng et al. | Development of a FLP/frt system for generating helper-dependent adenoviral vectors | |
| JP2021520800A5 (enExample) | ||
| Goncalves et al. | Concerted nicking of donor and chromosomal acceptor DNA promotes homology-directed gene targeting in human cells | |
| RU2457250C2 (ru) | Способы и композиции для экспрессии антисмысловой вирусной рнк в клетках собаки | |
| JP2017519774A5 (enExample) | ||
| Nguyen et al. | Novel promoters derived from Chinese hamster ovary cells via in silico and in vitro analysis | |
| JP2017501685A5 (enExample) | ||
| JP2018534937A5 (enExample) | ||
| JP2010539920A5 (enExample) | ||
| JP2022528010A5 (enExample) | ||
| ES2398984T3 (es) | RT-PCR rápida en una etapa | |
| JP2023549357A5 (enExample) | ||
| Broecker et al. | The intron-enriched HERV-K (HML-10) family suppresses apoptosis, an indicator of malignant transformation | |
| CN101613756B (zh) | 用于多重连接扩增技术的长探针的制备方法 | |
| Singh et al. | Human SAP18 mediates assembly of a splicing regulatory multiprotein complex via its ubiquitin-like fold | |
| CN101139615A (zh) | 一种快速高效构建哺乳动物细胞rna干扰载体及其验证载体的方法 | |
| Deng et al. | Role of the influenza virus heterotrimeric RNA polymerase complex in the initiation of replication | |
| CN107686846A (zh) | 一种双荧光报告重组质粒载体及其构建方法和应用 | |
| Fell et al. | Precise kilobase-scale genomic insertions in mammalian cells using PASTE | |
| WO2021226278A1 (en) | An ultrasensitive rapid and portable case13d-based diagnostic assay | |
| CN120718906B (zh) | 一种优化的ωRNA及其基因编辑应用 |