JP2019501687A - Vegf拮抗薬を収容したプレフィルドプラスチックシリンジ - Google Patents

Vegf拮抗薬を収容したプレフィルドプラスチックシリンジ Download PDF

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Publication number
JP2019501687A
JP2019501687A JP2018525783A JP2018525783A JP2019501687A JP 2019501687 A JP2019501687 A JP 2019501687A JP 2018525783 A JP2018525783 A JP 2018525783A JP 2018525783 A JP2018525783 A JP 2018525783A JP 2019501687 A JP2019501687 A JP 2019501687A
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JP
Japan
Prior art keywords
syringe
prefilled syringe
prefilled
vegf
silicone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018525783A
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English (en)
Japanese (ja)
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JP2019501687A5 (enExample
Inventor
フィードラー、ベルント
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Formycon AG
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Formycon AG
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Publication of JP2019501687A publication Critical patent/JP2019501687A/ja
Publication of JP2019501687A5 publication Critical patent/JP2019501687A5/ja
Priority to JP2022144630A priority Critical patent/JP2022177129A/ja
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/048Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/28Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501Means for blocking or restricting the movement of the rod or piston
    • A61M5/31505Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31513Piston constructions to improve sealing or sliding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3286Needle tip design, e.g. for improved penetration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • A61M2005/3131Syringe barrels specially adapted for improving sealing or sliding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/002Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Surgery (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2018525783A 2015-11-18 2016-11-18 Vegf拮抗薬を収容したプレフィルドプラスチックシリンジ Pending JP2019501687A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022144630A JP2022177129A (ja) 2015-11-18 2022-09-12 Vegf拮抗薬を収容したプレフィルドプラスチックシリンジ

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15195177 2015-11-18
EP15195177.9 2015-11-18
PCT/EP2016/078136 WO2017085253A1 (en) 2015-11-18 2016-11-18 Pre-filled plastic syringe containing a vegf antagonist

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022144630A Division JP2022177129A (ja) 2015-11-18 2022-09-12 Vegf拮抗薬を収容したプレフィルドプラスチックシリンジ

Publications (2)

Publication Number Publication Date
JP2019501687A true JP2019501687A (ja) 2019-01-24
JP2019501687A5 JP2019501687A5 (enExample) 2020-01-09

Family

ID=54608352

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018525783A Pending JP2019501687A (ja) 2015-11-18 2016-11-18 Vegf拮抗薬を収容したプレフィルドプラスチックシリンジ
JP2022144630A Pending JP2022177129A (ja) 2015-11-18 2022-09-12 Vegf拮抗薬を収容したプレフィルドプラスチックシリンジ

Family Applications After (1)

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JP2022144630A Pending JP2022177129A (ja) 2015-11-18 2022-09-12 Vegf拮抗薬を収容したプレフィルドプラスチックシリンジ

Country Status (12)

Country Link
US (3) US20180326126A1 (enExample)
EP (1) EP3377151A1 (enExample)
JP (2) JP2019501687A (enExample)
KR (1) KR20180083377A (enExample)
CN (1) CN108290004A (enExample)
AU (1) AU2016356047B2 (enExample)
BR (1) BR112018010005A2 (enExample)
CA (1) CA3005692A1 (enExample)
MX (1) MX2018006171A (enExample)
RU (1) RU2018121813A (enExample)
WO (1) WO2017085253A1 (enExample)
ZA (1) ZA201802922B (enExample)

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JP2023537962A (ja) * 2020-08-12 2023-09-06 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 眼球組織への薬物送達のためのシステムおよび方法

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US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
WO2017117464A1 (en) 2015-12-30 2017-07-06 Kodiak Sciences Inc. Antibodies and conjugates thereof
US10576128B2 (en) 2016-01-26 2020-03-03 Formycon Ag Liquid formulation of a VEGF antagonist
MX2020006177A (es) 2017-12-13 2020-09-03 Regeneron Pharma Dispositivos y metodos para administracion exacta de dosis.
WO2019136163A1 (en) 2018-01-03 2019-07-11 Irenix Medical, Inc. Therapeutic agent delivery devices having integrated pain mitigation, and methods for using the same
US11524053B2 (en) 2018-01-26 2022-12-13 The Regents Of The University Of California Methods and compositions for treatment of angiogenic disorders using anti-VEGF agents
BR112020017872A2 (pt) 2018-03-02 2020-12-22 Kodiak Sciences Inc. Anticorpos de il-6 e construtos de fusão e conjugados dos mesmos
NZ770284A (en) 2018-05-10 2025-11-28 Regeneron Pharma High concentration vegf receptor fusion protein containing formulations
KR102467349B1 (ko) * 2018-10-29 2022-11-16 에프. 호프만-라 로슈 아게 항체 제형
EP3659594B1 (de) * 2018-11-30 2020-11-18 Klaus Stegemann Eine sterile lösung mit einem medizinischen wirkstoff enthaltende applikationsspritze und verfahren für deren bereitstellung
CN118718180A (zh) 2019-06-05 2024-10-01 里珍纳龙药品有限公司 用于精确剂量递送的装置及方法
CA3150481A1 (en) 2019-09-03 2021-03-11 Amgen Inc. Injection device for drug delivery and packaging for the injection device
JP7704740B2 (ja) 2019-09-16 2025-07-08 アムジエン・インコーポレーテツド 薬物送達デバイスの外部滅菌の方法
WO2021072265A1 (en) 2019-10-10 2021-04-15 Kodiak Sciences Inc. Methods of treating an eye disorder
IL293131A (en) 2019-11-25 2022-07-01 Univ California Long-acting vegf inhibitors for intraocular neovascularization
JP2022548197A (ja) * 2019-12-06 2022-11-17 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 抗vegfタンパク質組成物及びその製造方法
CN115803009A (zh) 2020-05-08 2023-03-14 瑞泽恩制药公司 用于治疗眼病和癌症的vegf阱和微阱及方法
WO2022067330A1 (en) * 2020-09-25 2022-03-31 Ocuject, Llc Syringe injector with a feedback mechanism
KR102720956B1 (ko) * 2020-12-15 2024-10-24 삼천당제약주식회사 안과용 제형을 포함하는 시린지

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US20140305830A1 (en) * 2013-04-11 2014-10-16 Schott Ag Container with low particulate emission and friction controlled dry sliding surface and methods for producing same
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JP2015042638A (ja) * 2008-02-07 2015-03-05 アムジエン・インコーポレーテツド 安定化されたタンパク質組成物
JP2014523271A (ja) * 2011-05-27 2014-09-11 ダブリュ.エル.ゴア アンド アソシエイツ,インコーポレイティド 容器向けのフルオロポリマーバリア材料
WO2013115331A1 (ja) * 2012-01-31 2013-08-08 テルモ株式会社 プレフィルドシリンジ用シリンジ
JP2015517860A (ja) * 2012-06-01 2015-06-25 ノバルティス アーゲー 注射器
JP2014028114A (ja) * 2012-07-03 2014-02-13 Novartis Ag 注射器
JP2014087678A (ja) * 2012-07-03 2014-05-15 Novartis Ag 注射器
JP2015528454A (ja) * 2012-08-28 2015-09-28 ノバルティス アーゲー 眼血管増殖性疾患の処置におけるvegfアンタゴニストの使用
US20140305830A1 (en) * 2013-04-11 2014-10-16 Schott Ag Container with low particulate emission and friction controlled dry sliding surface and methods for producing same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023537962A (ja) * 2020-08-12 2023-09-06 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 眼球組織への薬物送達のためのシステムおよび方法
JP7756706B2 (ja) 2020-08-12 2025-10-20 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 眼球組織への薬物送達のためのシステムおよび方法

Also Published As

Publication number Publication date
AU2016356047A1 (en) 2018-05-24
RU2018121813A (ru) 2019-12-19
US20180326126A1 (en) 2018-11-15
AU2016356047B2 (en) 2021-10-21
RU2018121813A3 (enExample) 2020-03-05
KR20180083377A (ko) 2018-07-20
EP3377151A1 (en) 2018-09-26
WO2017085253A1 (en) 2017-05-26
ZA201802922B (en) 2019-06-26
CA3005692A1 (en) 2017-05-26
BR112018010005A2 (pt) 2018-11-21
JP2022177129A (ja) 2022-11-30
CN108290004A (zh) 2018-07-17
US20250229010A1 (en) 2025-07-17
US20220362441A1 (en) 2022-11-17
MX2018006171A (es) 2018-12-19

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