JP2019501687A5 - - Google Patents
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- Publication number
- JP2019501687A5 JP2019501687A5 JP2018525783A JP2018525783A JP2019501687A5 JP 2019501687 A5 JP2019501687 A5 JP 2019501687A5 JP 2018525783 A JP2018525783 A JP 2018525783A JP 2018525783 A JP2018525783 A JP 2018525783A JP 2019501687 A5 JP2019501687 A5 JP 2019501687A5
- Authority
- JP
- Japan
- Prior art keywords
- syringe
- prefilled syringe
- prefilled
- vegf
- silicone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229940071643 prefilled syringe Drugs 0.000 claims 16
- 239000005557 antagonist Substances 0.000 claims 6
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 4
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 4
- 239000007788 liquid Substances 0.000 claims 4
- 238000002360 preparation method Methods 0.000 claims 4
- 206010012688 Diabetic retinal oedema Diseases 0.000 claims 3
- 206010047571 Visual impairment Diseases 0.000 claims 3
- 201000011190 diabetic macular edema Diseases 0.000 claims 3
- 239000012669 liquid formulation Substances 0.000 claims 3
- 208000029257 vision disease Diseases 0.000 claims 3
- 230000004393 visual impairment Effects 0.000 claims 3
- 208000005590 Choroidal Neovascularization Diseases 0.000 claims 2
- 206010060823 Choroidal neovascularisation Diseases 0.000 claims 2
- 229920000089 Cyclic olefin copolymer Polymers 0.000 claims 2
- 206010064930 age-related macular degeneration Diseases 0.000 claims 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 208000030533 eye disease Diseases 0.000 claims 2
- 208000002780 macular degeneration Diseases 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 208000004644 retinal vein occlusion Diseases 0.000 claims 2
- 206010012689 Diabetic retinopathy Diseases 0.000 claims 1
- 208000001344 Macular Edema Diseases 0.000 claims 1
- 206010025415 Macular oedema Diseases 0.000 claims 1
- 206010073286 Pathologic myopia Diseases 0.000 claims 1
- 108091008605 VEGF receptors Proteins 0.000 claims 1
- 102000009484 Vascular Endothelial Growth Factor Receptors Human genes 0.000 claims 1
- 229960002833 aflibercept Drugs 0.000 claims 1
- 108010081667 aflibercept Proteins 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 201000005667 central retinal vein occlusion Diseases 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 201000010230 macular retinal edema Diseases 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 claims 1
- 229960003876 ranibizumab Drugs 0.000 claims 1
- 230000002207 retinal effect Effects 0.000 claims 1
- 210000001957 retinal vein Anatomy 0.000 claims 1
- 239000004447 silicone coating Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022144630A JP2022177129A (ja) | 2015-11-18 | 2022-09-12 | Ｖｅｇｆ拮抗薬を収容したプレフィルドプラスチックシリンジ |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15195177 | 2015-11-18 | ||
| EP15195177.9 | 2015-11-18 | ||
| PCT/EP2016/078136 WO2017085253A1 (en) | 2015-11-18 | 2016-11-18 | Pre-filled plastic syringe containing a vegf antagonist |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022144630A Division JP2022177129A (ja) | 2015-11-18 | 2022-09-12 | Ｖｅｇｆ拮抗薬を収容したプレフィルドプラスチックシリンジ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019501687A JP2019501687A (ja) | 2019-01-24 |
| JP2019501687A5 true JP2019501687A5 (enExample) | 2020-01-09 |
Family
ID=54608352
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018525783A Pending JP2019501687A (ja) | 2015-11-18 | 2016-11-18 | Ｖｅｇｆ拮抗薬を収容したプレフィルドプラスチックシリンジ |
| JP2022144630A Pending JP2022177129A (ja) | 2015-11-18 | 2022-09-12 | Ｖｅｇｆ拮抗薬を収容したプレフィルドプラスチックシリンジ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022144630A Pending JP2022177129A (ja) | 2015-11-18 | 2022-09-12 | Ｖｅｇｆ拮抗薬を収容したプレフィルドプラスチックシリンジ |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20180326126A1 (enExample) |
| EP (1) | EP3377151A1 (enExample) |
| JP (2) | JP2019501687A (enExample) |
| KR (1) | KR20180083377A (enExample) |
| CN (1) | CN108290004A (enExample) |
| AU (1) | AU2016356047B2 (enExample) |
| BR (1) | BR112018010005A2 (enExample) |
| MX (1) | MX2018006171A (enExample) |
| RU (1) | RU2018121813A (enExample) |
| WO (1) | WO2017085253A1 (enExample) |
| ZA (1) | ZA201802922B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015200905A2 (en) | 2014-06-28 | 2015-12-30 | Oligasis, Llc | Dual pdgf/vegf antagonists |
| IL290457B2 (en) | 2015-12-30 | 2025-02-01 | Kodiak Sciences Inc | Antibodies and their conjugates |
| EP3407868A1 (en) | 2016-01-26 | 2018-12-05 | Formycon AG | Liquid formulation of a vegf antagonist |
| IL318292A (en) | 2017-12-13 | 2025-03-01 | Regeneron Pharma | Devices and methods for administering precise doses |
| WO2019136163A1 (en) | 2018-01-03 | 2019-07-11 | Irenix Medical, Inc. | Therapeutic agent delivery devices having integrated pain mitigation, and methods for using the same |
| US11524053B2 (en) | 2018-01-26 | 2022-12-13 | The Regents Of The University Of California | Methods and compositions for treatment of angiogenic disorders using anti-VEGF agents |
| CN111699004A (zh) | 2018-02-06 | 2020-09-22 | 豪夫迈·罗氏有限公司 | 眼科疾病的治疗 |
| CA3092588A1 (en) | 2018-03-02 | 2019-09-06 | Kodiak Sciences Inc. | Il-6 antibodies and fusion constructs and conjugates thereof |
| RS67656B1 (sr) | 2018-05-10 | 2026-02-27 | Regeneron Pharma | Formulacije koje sadrže visoke koncentracije fuzionog proteina vegf receptora |
| CN119033684A (zh) | 2018-10-29 | 2024-11-29 | 豪夫迈·罗氏有限公司 | 抗体制剂 |
| ES2841807T5 (en) * | 2018-11-30 | 2026-06-30 | Klaus Stegemann | A sterile solution with an application injector comprising a medical agent and method for producing same |
| PE20240329A1 (es) | 2019-06-05 | 2024-02-27 | Regeneron Pharma | Dispositivos y metodos para administracion de dosis de precision |
| US12059555B2 (en) | 2019-09-03 | 2024-08-13 | Amgen Inc. | Injection device for drug delivery and packaging for the injection device |
| MX2022002980A (es) | 2019-09-16 | 2022-04-06 | Amgen Inc | Metodo para la esterilizacion externa de un dispositivo de suministro de farmacos. |
| CA3157509A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| CN114867487A (zh) | 2019-11-25 | 2022-08-05 | 加利福尼亚大学董事会 | 用于眼内新生血管的长效vegf抑制剂 |
| IL309560B2 (en) | 2019-12-06 | 2025-05-01 | Regeneron Pharma | Anti-VEGF protein preparations and methods for their production |
| MX2022013812A (es) | 2020-05-08 | 2022-12-15 | Regeneron Pharma | Trampas y mini-trampas de vegf y metodos para el tratamiento de trastornos oculares y cancer. |
| AU2021325994A1 (en) * | 2020-08-12 | 2023-03-09 | Regeneron Pharmaceuticals, Inc. | Systems and methods for drug delivery to ocular tissue |
| US20230226280A1 (en) * | 2020-09-25 | 2023-07-20 | Ocuject, Llc | Syringe injector with a feedback mechanism |
| KR102720956B1 (ko) * | 2020-12-15 | 2024-10-24 | 삼천당제약주식회사 | 안과용 제형을 포함하는 시린지 |
| EP4313211A1 (en) * | 2021-03-30 | 2024-02-07 | SCHOTT Pharma Schweiz AG | System for low-temperature storage of a pharmaceutical composition, liquid composition, method and uses |
| US12649031B2 (en) | 2021-09-08 | 2026-06-09 | Regeneron Pharmaceuticals, Inc. | Methods for delivering agents with pre-filled syringes to minimize intraocular inflammation |
| USD1120314S1 (en) | 2022-11-30 | 2026-03-24 | Regeneron Pharmaceuticals, Inc. | Dose delivery device |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3380450A (en) * | 1965-05-10 | 1968-04-30 | William H. Adelberger | Sterile disposable plastic prefilled syringe |
| US5731424A (en) | 1990-06-11 | 1998-03-24 | Nexstar Pharmaceuticals, Inc. | High affinity TGFβ nucleic acid ligands and inhibitors |
| US6124449A (en) | 1990-06-11 | 2000-09-26 | Nexstar Pharmaceuticals, Inc. | High affinity TGFβ nucleic acid ligands and inhibitors |
| US5731144A (en) | 1990-06-11 | 1998-03-24 | Nexstar Pharmaceuticals, Inc. | High affinity TGFβ nucleic acid ligands |
| US6582959B2 (en) | 1991-03-29 | 2003-06-24 | Genentech, Inc. | Antibodies to vascular endothelial cell growth factor |
| KR100335584B1 (ko) | 1992-10-28 | 2002-11-29 | 제넨테크, 인코포레이티드 | 혈관내피세포성장인자에대한길항제 |
| IL117645A (en) | 1995-03-30 | 2005-08-31 | Genentech Inc | Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration |
| ES2276405T3 (es) | 1995-06-02 | 2007-06-16 | Gilead Sciences, Inc. | Ligandos de oligonucleotidos de alta afinidad a pdgf. |
| US20020032315A1 (en) | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
| CN104231078A (zh) | 1997-04-07 | 2014-12-24 | 基因技术股份有限公司 | 抗-血管内皮生长因子的抗体 |
| DE69829891T2 (de) | 1997-04-07 | 2005-10-06 | Genentech, Inc., South San Francisco | Anti-VEGF Antikörper |
| US6703020B1 (en) | 1999-04-28 | 2004-03-09 | Board Of Regents, The University Of Texas System | Antibody conjugate methods for selectively inhibiting VEGF |
| CN101433715B (zh) | 1999-06-08 | 2013-04-17 | 里珍纳龙药品有限公司 | 具有改善的药物动力学特性的修饰嵌合多肽 |
| US7431989B2 (en) | 2003-05-06 | 2008-10-07 | Tribofilm Research, Inc. | Article with lubricated surface and method |
| WO2005044853A2 (en) | 2003-11-01 | 2005-05-19 | Genentech, Inc. | Anti-vegf antibodies |
| EP2249801A2 (en) * | 2008-02-07 | 2010-11-17 | Amgen Inc. | Stabilized protein compositions |
| KR20180005753A (ko) | 2008-06-25 | 2018-01-16 | 에스바테크 - 어 노바티스 컴파니 엘엘씨 | Ｖｅｇｆ를 억제하는 안정하고 가용성인 항체 |
| NZ592591A (en) | 2008-11-03 | 2012-04-27 | Molecular Partners Ag | Binding proteins comprising ankyrin repeast domains that inhibit the vegf-a receptor interaction |
| US9597458B2 (en) * | 2009-10-29 | 2017-03-21 | W. L. Gore & Associates, Inc. | Fluoropolymer barrier materials for containers |
| WO2011117878A1 (en) | 2010-03-20 | 2011-09-29 | Pawan Trilokchand Agrawal | Plastic pre-filled syringe |
| AU2011235002B2 (en) * | 2010-03-31 | 2016-08-11 | Ocuject, Llc | Device and method for intraocular drug delivery |
| TWI510246B (zh) | 2010-04-30 | 2015-12-01 | Molecular Partners Ag | 抑制ｖｅｇｆ－ａ受體交互作用的經修飾結合性蛋白質 |
| DE102011009057B4 (de) * | 2011-01-20 | 2015-12-10 | Schott Ag | Plasma-Behandlungsvorrichtung zur Herstellung von Beschichtungen und Verfahren zur innenseitigen Plasmabehandlung von Behältern |
| JP6207401B2 (ja) * | 2012-01-31 | 2017-10-04 | テルモ株式会社 | プレフィルドシリンジ用シリンジ |
| HUE055994T2 (hu) * | 2012-06-01 | 2022-01-28 | Novartis Ag | Fecskendõ |
| AU2012101678B4 (en) | 2012-07-03 | 2013-01-24 | Novartis Ag | Use of device |
| DE202013000688U1 (de) * | 2012-07-03 | 2013-03-05 | Novartis Ag | Glas-Spritze |
| WO2014033184A1 (en) * | 2012-08-28 | 2014-03-06 | Novartis Ag | Use of a vegf antagonist in treating ocular vascular proliferative diseases |
| DE102013103676A1 (de) * | 2013-04-11 | 2014-10-30 | Schott Ag | Behälter mit geringer Partikelemission und reibkontrollierter Trockengleitoberfläche, sowie Verfahren zu dessen Herstellung |
| BR112016000177A2 (pt) * | 2013-07-11 | 2017-12-12 | Novartis Ag | usos de um antagonista do vegf no tratamento de doenças neovasculares coriorretinianas e de permeabilidade em pacientes pediátricos, seringa pré-cheia, kit e formulação de liberação lenta |
| CA3246118A1 (en) * | 2013-10-07 | 2025-02-21 | Ocuject, Llc | Intraocular delivery devices and methods therefor |
| WO2016051962A1 (ja) * | 2014-10-02 | 2016-04-07 | テルモ株式会社 | タンパク質溶液製剤を収容するための医療用容器 |
-
2016
- 2016-11-18 US US15/776,418 patent/US20180326126A1/en not_active Abandoned
- 2016-11-18 WO PCT/EP2016/078136 patent/WO2017085253A1/en not_active Ceased
- 2016-11-18 CN CN201680067304.7A patent/CN108290004A/zh active Pending
- 2016-11-18 MX MX2018006171A patent/MX2018006171A/es unknown
- 2016-11-18 JP JP2018525783A patent/JP2019501687A/ja active Pending
- 2016-11-18 BR BR112018010005A patent/BR112018010005A2/pt not_active IP Right Cessation
- 2016-11-18 KR KR1020187016631A patent/KR20180083377A/ko not_active Withdrawn
- 2016-11-18 EP EP16801743.2A patent/EP3377151A1/en active Pending
- 2016-11-18 AU AU2016356047A patent/AU2016356047B2/en active Active
- 2016-11-18 RU RU2018121813A patent/RU2018121813A/ru unknown
-
2018
- 2018-05-04 ZA ZA2018/02922A patent/ZA201802922B/en unknown
-
2022
- 2022-07-18 US US17/867,098 patent/US20220362441A1/en not_active Abandoned
- 2022-09-12 JP JP2022144630A patent/JP2022177129A/ja active Pending
-
2025
- 2025-04-03 US US19/169,549 patent/US20250229010A1/en active Pending
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