JP2019162150A5 - - Google Patents
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- JP2019162150A5 JP2019162150A5 JP2019114273A JP2019114273A JP2019162150A5 JP 2019162150 A5 JP2019162150 A5 JP 2019162150A5 JP 2019114273 A JP2019114273 A JP 2019114273A JP 2019114273 A JP2019114273 A JP 2019114273A JP 2019162150 A5 JP2019162150 A5 JP 2019162150A5
- Authority
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- Japan
- Prior art keywords
- level
- gene
- cell carcinoma
- renal cell
- rna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108090000623 proteins and genes Proteins 0.000 claims 24
- 238000000034 method Methods 0.000 claims 23
- 208000006265 Renal cell carcinoma Diseases 0.000 claims 15
- 102100020997 Fractalkine Human genes 0.000 claims 12
- 101000854520 Homo sapiens Fractalkine Proteins 0.000 claims 12
- 108091058560 IL8 Proteins 0.000 claims 11
- 102000004889 Interleukin-6 Human genes 0.000 claims 11
- 108090001005 Interleukin-6 Proteins 0.000 claims 11
- 102000004890 Interleukin-8 Human genes 0.000 claims 11
- 108090001007 Interleukin-8 Proteins 0.000 claims 11
- 206010028980 Neoplasm Diseases 0.000 claims 9
- 102100032367 C-C motif chemokine 5 Human genes 0.000 claims 8
- 102100031618 HLA class II histocompatibility antigen, DP beta 1 chain Human genes 0.000 claims 8
- 108010045483 HLA-DPB1 antigen Proteins 0.000 claims 8
- 101000797762 Homo sapiens C-C motif chemokine 5 Proteins 0.000 claims 8
- 101710168942 Sphingosine-1-phosphate phosphatase 1 Proteins 0.000 claims 8
- 102100030684 Sphingosine-1-phosphate phosphatase 1 Human genes 0.000 claims 8
- 102100036170 C-X-C motif chemokine 9 Human genes 0.000 claims 6
- 101000947172 Homo sapiens C-X-C motif chemokine 9 Proteins 0.000 claims 6
- 101000946843 Homo sapiens T-cell surface glycoprotein CD8 alpha chain Proteins 0.000 claims 6
- 102100034922 T-cell surface glycoprotein CD8 alpha chain Human genes 0.000 claims 6
- 101001128156 Homo sapiens Nanos homolog 3 Proteins 0.000 claims 5
- 101001124309 Homo sapiens Nitric oxide synthase, endothelial Proteins 0.000 claims 5
- 102100028452 Nitric oxide synthase, endothelial Human genes 0.000 claims 5
- 230000002596 correlated effect Effects 0.000 claims 5
- 210000001519 tissue Anatomy 0.000 claims 5
- 102100036301 C-C chemokine receptor type 7 Human genes 0.000 claims 4
- 102100025248 C-X-C motif chemokine 10 Human genes 0.000 claims 4
- 101000716065 Homo sapiens C-C chemokine receptor type 7 Proteins 0.000 claims 4
- 101000858088 Homo sapiens C-X-C motif chemokine 10 Proteins 0.000 claims 4
- 101001003581 Homo sapiens Lamin-B1 Proteins 0.000 claims 4
- 102100026517 Lamin-B1 Human genes 0.000 claims 4
- 210000001165 lymph node Anatomy 0.000 claims 4
- 230000017074 necrotic cell death Effects 0.000 claims 4
- 230000008595 infiltration Effects 0.000 claims 3
- 238000001764 infiltration Methods 0.000 claims 3
- 238000010606 normalization Methods 0.000 claims 3
- 102100036517 Apolipoprotein L domain-containing protein 1 Human genes 0.000 claims 1
- 108010062802 CD66 antigens Proteins 0.000 claims 1
- 102100024533 Carcinoembryonic antigen-related cell adhesion molecule 1 Human genes 0.000 claims 1
- 102100027641 DNA-binding protein inhibitor ID-1 Human genes 0.000 claims 1
- 102100032340 G2/mitotic-specific cyclin-B1 Human genes 0.000 claims 1
- 101000928701 Homo sapiens Apolipoprotein L domain-containing protein 1 Proteins 0.000 claims 1
- 101000983518 Homo sapiens Caspase-10 Proteins 0.000 claims 1
- 101001081590 Homo sapiens DNA-binding protein inhibitor ID-1 Proteins 0.000 claims 1
- 101000868643 Homo sapiens G2/mitotic-specific cyclin-B1 Proteins 0.000 claims 1
- 101001091194 Homo sapiens Peptidyl-prolyl cis-trans isomerase G Proteins 0.000 claims 1
- 101001126234 Homo sapiens Phospholipid phosphatase 3 Proteins 0.000 claims 1
- 101000971400 Homo sapiens Protein kinase C eta type Proteins 0.000 claims 1
- 101000864800 Homo sapiens Serine/threonine-protein kinase Sgk1 Proteins 0.000 claims 1
- 102100034850 Peptidyl-prolyl cis-trans isomerase G Human genes 0.000 claims 1
- 102100030450 Phospholipid phosphatase 3 Human genes 0.000 claims 1
- 102100021556 Protein kinase C eta type Human genes 0.000 claims 1
- 102100030070 Serine/threonine-protein kinase Sgk1 Human genes 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 230000009545 invasion Effects 0.000 claims 1
- 230000036210 malignancy Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021112234A JP7385630B2 (ja) | 2010-01-11 | 2021-07-06 | 遺伝子発現を用いて腎癌の臨床的結果の見込みを判定する方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29403810P | 2010-01-11 | 2010-01-11 | |
| US61/294,038 | 2010-01-11 | ||
| US34623010P | 2010-05-19 | 2010-05-19 | |
| US61/346,230 | 2010-05-19 | ||
| JP2017080314A JP6546214B2 (ja) | 2010-01-11 | 2017-04-14 | 遺伝子発現を用いて腎癌の臨床的結果の見込みを判定する方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017080314A Division JP6546214B2 (ja) | 2010-01-11 | 2017-04-14 | 遺伝子発現を用いて腎癌の臨床的結果の見込みを判定する方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021112234A Division JP7385630B2 (ja) | 2010-01-11 | 2021-07-06 | 遺伝子発現を用いて腎癌の臨床的結果の見込みを判定する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019162150A JP2019162150A (ja) | 2019-09-26 |
| JP2019162150A5 true JP2019162150A5 (https=) | 2020-01-09 |
| JP7307602B2 JP7307602B2 (ja) | 2023-07-12 |
Family
ID=44258831
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012548188A Active JP6286124B2 (ja) | 2010-01-11 | 2011-01-07 | 遺伝子発現を用いて腎癌の臨床的結果の見込みを判定する方法 |
| JP2016041689A Pending JP2016174600A (ja) | 2010-01-11 | 2016-03-04 | 遺伝子発現を用いて腎癌の臨床的結果の見込みを判定する方法 |
| JP2017080314A Active JP6546214B2 (ja) | 2010-01-11 | 2017-04-14 | 遺伝子発現を用いて腎癌の臨床的結果の見込みを判定する方法 |
| JP2019114273A Active JP7307602B2 (ja) | 2010-01-11 | 2019-06-20 | 遺伝子発現を用いて腎癌の臨床的結果の見込みを判定する方法 |
| JP2021112234A Active JP7385630B2 (ja) | 2010-01-11 | 2021-07-06 | 遺伝子発現を用いて腎癌の臨床的結果の見込みを判定する方法 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012548188A Active JP6286124B2 (ja) | 2010-01-11 | 2011-01-07 | 遺伝子発現を用いて腎癌の臨床的結果の見込みを判定する方法 |
| JP2016041689A Pending JP2016174600A (ja) | 2010-01-11 | 2016-03-04 | 遺伝子発現を用いて腎癌の臨床的結果の見込みを判定する方法 |
| JP2017080314A Active JP6546214B2 (ja) | 2010-01-11 | 2017-04-14 | 遺伝子発現を用いて腎癌の臨床的結果の見込みを判定する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021112234A Active JP7385630B2 (ja) | 2010-01-11 | 2021-07-06 | 遺伝子発現を用いて腎癌の臨床的結果の見込みを判定する方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US9551034B2 (https=) |
| EP (5) | EP3178944B1 (https=) |
| JP (5) | JP6286124B2 (https=) |
| AU (1) | AU2011203977B2 (https=) |
| CA (3) | CA3128103C (https=) |
| DK (1) | DK3178944T3 (https=) |
| ES (2) | ES2741379T3 (https=) |
| IL (6) | IL219978A (https=) |
| MX (3) | MX341866B (https=) |
| NZ (4) | NZ617003A (https=) |
| SG (1) | SG181806A1 (https=) |
| WO (1) | WO2011085263A2 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3178944B1 (en) | 2010-01-11 | 2019-05-15 | Genomic Health, Inc. | Method to use gene expression to determine likelihood of clinical outcome of renal cancer |
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| SG187045A1 (en) | 2010-08-13 | 2013-02-28 | Somalogic Inc | Pancreatic cancer biomarkers and uses thereof |
| WO2013016673A2 (en) * | 2011-07-27 | 2013-01-31 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of dpep1 and tpx2 expression for evaluating treatment or survival time of patients with pancreatic ductal adenocarcinoma |
| EP2748356A2 (en) * | 2011-08-22 | 2014-07-02 | Somalogic, Inc. | Renal cell carcinoma biomarkers and uses thereof |
| HK1212389A1 (en) | 2011-10-24 | 2016-06-10 | Signalchem Lifesciences Corporation | Carbonic anhydrase ix-related markers and use thereof |
| US8725426B2 (en) | 2012-01-31 | 2014-05-13 | Genomic Health, Inc. | Gene expression profile algorithm and test for determining prognosis of prostate cancer |
| JP2016521979A (ja) * | 2013-05-30 | 2016-07-28 | ジェノミック ヘルス， インコーポレイテッド | 腎臓がんを有する患者に対する再発スコアを計算するための遺伝子発現プロファイルアルゴリズム |
| SG11201602019XA (en) * | 2013-09-17 | 2016-04-28 | Agency Science Tech & Res | Multigene assay for prognosis of renal cancer |
| WO2016034611A1 (en) * | 2014-09-02 | 2016-03-10 | Max-Delbrück-Centrum für Molekulare Medizin | Antisense oligonucleotides targeting 3'utr region of a20 |
| JP6638128B2 (ja) * | 2014-10-30 | 2020-01-29 | 公立大学法人福島県立医科大学 | 腎がんの悪性度の検査マーカー及び検査方法 |
| WO2016126883A1 (en) * | 2015-02-03 | 2016-08-11 | Cedars-Sinai Medical Center | Biomarker based prognostic model for predicting overall survival in patients with metastatic clear cell kidney cancer |
| GB201616912D0 (en) | 2016-10-05 | 2016-11-16 | University Of East Anglia | Classification of cancer |
| CN110546277B (zh) | 2017-03-01 | 2024-06-11 | 豪夫迈·罗氏有限公司 | 用于癌症的诊断和治疗方法 |
| WO2018161027A1 (en) * | 2017-03-03 | 2018-09-07 | Oregon State University | Antisense antibacterial compounds and methods |
| US10636512B2 (en) | 2017-07-14 | 2020-04-28 | Cofactor Genomics, Inc. | Immuno-oncology applications using next generation sequencing |
| US11335464B2 (en) * | 2018-01-12 | 2022-05-17 | Siemens Medical Solutions Usa, Inc. | Integrated precision medicine by combining quantitative imaging techniques with quantitative genomics for improved decision making |
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| WO2020085936A1 (ru) * | 2018-10-24 | 2020-04-30 | Общество С Ограниченной Ответственностью "Онкобокс" | Тест-классификатор клинического ответа на лечение сорафенибом индивидуальных пациентов с раком почки |
| US11845989B2 (en) | 2019-01-23 | 2023-12-19 | Regeneron Pharmaceuticals, Inc. | Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors |
| JP2022523301A (ja) | 2019-01-23 | 2022-04-22 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | アンジオポエチン様７（ａｎｇｐｔｌ７）阻害剤による眼疾患の治療 |
| WO2021030604A1 (en) * | 2019-08-14 | 2021-02-18 | University Of Massachusetts | Urinary rna signatures in renal cell carcinoma (rcc) |
| WO2022182768A1 (en) | 2021-02-26 | 2022-09-01 | Regeneron Pharmaceuticals, Inc. | Treatment of inflammation with glucocorticoids and angiopoietin-like 7 (angptl7) inhibitors |
| CN113025716A (zh) * | 2021-03-02 | 2021-06-25 | 北京大学第一医院 | 一种用于人肿瘤分级的基因组合及其用途 |
| CN113817816A (zh) * | 2021-10-08 | 2021-12-21 | 济南艾迪康医学检验中心有限公司 | 检测epas1基因突变的引物、试剂盒和方法 |
| WO2023080900A1 (en) * | 2021-11-05 | 2023-05-11 | Genentech, Inc. | Methods and compositions for classifying and treating kidney cancer |
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2011
- 2011-01-07 EP EP17153152.8A patent/EP3178944B1/en active Active
- 2011-01-07 CA CA3128103A patent/CA3128103C/en active Active
- 2011-01-07 EP EP19173150.4A patent/EP3561078A1/en not_active Withdrawn
- 2011-01-07 NZ NZ61700311A patent/NZ617003A/en unknown
- 2011-01-07 MX MX2012007882A patent/MX341866B/es active IP Right Grant
- 2011-01-07 MX MX2016010666A patent/MX375138B/es unknown
- 2011-01-07 WO PCT/US2011/020596 patent/WO2011085263A2/en not_active Ceased
- 2011-01-07 EP EP20210111.9A patent/EP3831964B1/en active Active
- 2011-01-07 CA CA3256492A patent/CA3256492A1/en active Pending
- 2011-01-07 AU AU2011203977A patent/AU2011203977B2/en active Active
- 2011-01-07 CA CA2783858A patent/CA2783858C/en active Active
- 2011-01-07 SG SG2012045142A patent/SG181806A1/en unknown
- 2011-01-07 EP EP15203193.6A patent/EP3029155A3/en not_active Withdrawn
- 2011-01-07 DK DK17153152.8T patent/DK3178944T3/da active
- 2011-01-07 NZ NZ600268A patent/NZ600268A/en unknown
- 2011-01-07 US US12/987,023 patent/US9551034B2/en active Active
- 2011-01-07 NZ NZ719474A patent/NZ719474A/en unknown
- 2011-01-07 ES ES17153152T patent/ES2741379T3/es active Active
- 2011-01-07 JP JP2012548188A patent/JP6286124B2/ja active Active
- 2011-01-07 NZ NZ705645A patent/NZ705645A/en unknown
- 2011-01-07 EP EP11732245.3A patent/EP2524055A4/en not_active Withdrawn
- 2011-01-07 ES ES20210111T patent/ES3027507T3/es active Active
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2012
- 2012-05-24 IL IL219978A patent/IL219978A/en active IP Right Grant
- 2012-07-05 MX MX2020009704A patent/MX2020009704A/es unknown
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2016
- 2016-03-04 JP JP2016041689A patent/JP2016174600A/ja active Pending
- 2016-12-05 US US15/368,979 patent/US10892038B2/en active Active
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2017
- 2017-04-06 IL IL251635A patent/IL251635B/en active IP Right Grant
- 2017-04-14 JP JP2017080314A patent/JP6546214B2/ja active Active
- 2017-12-14 IL IL256335A patent/IL256335B/en active IP Right Grant
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2018
- 2018-10-03 IL IL26210018A patent/IL262100B/en active IP Right Grant
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2019
- 2019-06-20 JP JP2019114273A patent/JP7307602B2/ja active Active
- 2019-10-24 IL IL270151A patent/IL270151B/en active IP Right Grant
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2020
- 2020-11-19 US US16/952,566 patent/US11776664B2/en active Active
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2021
- 2021-02-07 IL IL280689A patent/IL280689B/en unknown
- 2021-07-06 JP JP2021112234A patent/JP7385630B2/ja active Active
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2023
- 2023-08-23 US US18/454,312 patent/US12412642B2/en active Active
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