JP2018537536A - Ｈｅｒ２陽性転移性乳癌の治療のための組成物および方法 - Google Patents

Ｈｅｒ２陽性転移性乳癌の治療のための組成物および方法 Download PDF

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JP2018537536A
JP2018537536A JP2018549407A JP2018549407A JP2018537536A JP 2018537536 A JP2018537536 A JP 2018537536A JP 2018549407 A JP2018549407 A JP 2018549407A JP 2018549407 A JP2018549407 A JP 2018549407A JP 2018537536 A JP2018537536 A JP 2018537536A
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cancer
cells
activated
receptor
kit according
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JP2018537536A5 (enExample
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ラビザド，シャールーズ
スン−シオン，パトリック
クリングマン，ハンス
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Nant Holdings IP LLC
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    • A—HUMAN NECESSITIES
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    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/49—Breast
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cell Biology (AREA)
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JP2018549407A 2015-12-09 2016-12-09 Ｈｅｒ２陽性転移性乳癌の治療のための組成物および方法 Pending JP2018537536A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562265382P 2015-12-09 2015-12-09
US62/265,382 2015-12-09
PCT/US2016/066018 WO2017100709A1 (en) 2015-12-09 2016-12-09 Compositions and methods for treatment of her2 positive metastatic breast cancer

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JP2018537536A true JP2018537536A (ja) 2018-12-20
JP2018537536A5 JP2018537536A5 (enExample) 2019-12-12

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US (1) US20180360881A1 (enExample)
EP (1) EP3386522A4 (enExample)
JP (1) JP2018537536A (enExample)
KR (1) KR20180123214A (enExample)
CN (1) CN109475576A (enExample)
AU (1) AU2016366677A1 (enExample)
CA (1) CA3007996A1 (enExample)
WO (1) WO2017100709A1 (enExample)

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EP4650005A3 (en) 2016-07-15 2026-01-28 Viracta Subsidiary, Inc. Histone deacetylase inhibitors for use in immunotherapy
CN110769898A (zh) * 2017-06-22 2020-02-07 南加利福尼亚大学 使用嵌合抗原受体工程化自然杀伤细胞作为化学治疗药物运载体的联合癌症疗法
US11510982B2 (en) 2017-08-15 2022-11-29 Nantcell, Inc. HaNK cetuximab combinations and methods
CN110484507B (zh) * 2018-01-31 2023-10-13 温州医科大学 一种靶向肿瘤Her2的新型嵌合抗原受体T细胞的制备技术
IL321548A (en) * 2018-05-22 2025-08-01 Immunitybio Inc Recombinant NK cells expressing a chimeric antigen receptor (CAR) for epsilon-FC and uses thereof
BR112021001750A2 (pt) * 2018-08-06 2021-04-27 Daiichi Sankyo Company, Limited composição farmacêutica
KR20240162586A (ko) * 2018-10-31 2024-11-15 난트퀘스트, 인크. Pd-l1 키메라 항원 수용체-발현 nk 세포에 의한 pd-l1-양성 악성종양의 제거
US20220265716A1 (en) * 2019-07-26 2022-08-25 Nantkwest, Inc. Antibody pre-loaded cd16+nk-92 cells as an effective therapeutic product for tumor lysis
KR102594083B1 (ko) 2020-07-07 2023-10-25 칸큐어 엘엘씨 Mic 항체 및 결합제 및 이의 사용 방법
CN112675313A (zh) * 2020-12-28 2021-04-20 烟台大学 连接曲妥珠单抗片段的美登素纳米粒组合物
IL311003A (en) 2021-08-25 2024-04-01 Denali Therapeutics Inc Anti-2HER antibodies and methods of using them
CN114807237A (zh) * 2022-05-12 2022-07-29 广东普罗凯融生物医药科技有限公司 一种过表达CD16a的NK细胞的制备方法及其应用

Citations (3)

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US20040009169A1 (en) * 2002-02-25 2004-01-15 Julie Taylor Administration of agents for the treatment of inflammation
JP2012193180A (ja) * 2005-04-15 2012-10-11 Macrogenics Inc 共有結合型ダイアボディとその使用
JP2018509459A (ja) * 2015-03-27 2018-04-05 ナントクエスト インコーポレイテッド がん治療薬との併用療法におけるｎｋ−９２細胞

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JP5295568B2 (ja) * 2005-01-06 2013-09-18 ノヴォ ノルディスク アー／エス Ｋｉｒ結合剤およびその使用方法
EP2161339A1 (en) * 2008-08-29 2010-03-10 F. Hoffmann-La Roche Ag ADCC with modified NK92 cells
EP3701957B1 (en) * 2013-11-01 2022-12-28 ImmunityBio, Inc. Tumoricidal and antimicrobial compositions and methods
CN113699159A (zh) * 2014-03-28 2021-11-26 明尼苏达大学评议会 涉及经工程改造的cd16的多肽、细胞和方法

Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
US20040009169A1 (en) * 2002-02-25 2004-01-15 Julie Taylor Administration of agents for the treatment of inflammation
JP2005526045A (ja) * 2002-02-25 2005-09-02 エラン ファーマシューティカルズ，インコーポレイテッド 炎症の治療用薬剤の投与
JP2012193180A (ja) * 2005-04-15 2012-10-11 Macrogenics Inc 共有結合型ダイアボディとその使用
JP2018509459A (ja) * 2015-03-27 2018-04-05 ナントクエスト インコーポレイテッド がん治療薬との併用療法におけるｎｋ−９２細胞

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Title
CANCER RESEARCH, vol. 76(4)Supplement, JPN6021026601, February 2016 (2016-02-01), pages 2 - 11, ISSN: 0004545629 *
EJC SUPPLEMENTS, vol. 8(1), JPN6020046433, 2010, pages 1 - 10, ISSN: 0004639692 *
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医薬品添付文書 抗悪性腫瘍剤 パクリタキセル, JPN6021026600, September 2015 (2015-09-01), ISSN: 0004545628 *

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CA3007996A1 (en) 2017-06-15
WO2017100709A1 (en) 2017-06-15
AU2016366677A1 (en) 2018-07-26
EP3386522A4 (en) 2019-06-19
US20180360881A1 (en) 2018-12-20
CN109475576A (zh) 2019-03-15
EP3386522A1 (en) 2018-10-17
KR20180123214A (ko) 2018-11-15

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