JP2018536175A5 - - Google Patents
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- Publication number
- JP2018536175A5 JP2018536175A5 JP2018542117A JP2018542117A JP2018536175A5 JP 2018536175 A5 JP2018536175 A5 JP 2018536175A5 JP 2018542117 A JP2018542117 A JP 2018542117A JP 2018542117 A JP2018542117 A JP 2018542117A JP 2018536175 A5 JP2018536175 A5 JP 2018536175A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- amount
- component
- biological sample
- heterogeneous biological
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108090000623 proteins and genes Proteins 0.000 claims 32
- 102000004169 proteins and genes Human genes 0.000 claims 32
- 238000000034 method Methods 0.000 claims 22
- 206010028980 Neoplasm Diseases 0.000 claims 20
- 239000012472 biological sample Substances 0.000 claims 14
- 210000004027 cell Anatomy 0.000 claims 12
- 210000002865 immune cell Anatomy 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 238000004458 analytical method Methods 0.000 claims 5
- 201000011510 cancer Diseases 0.000 claims 5
- 239000000523 sample Substances 0.000 claims 5
- 238000004949 mass spectrometry Methods 0.000 claims 4
- 208000035269 cancer or benign tumor Diseases 0.000 claims 3
- 238000010195 expression analysis Methods 0.000 claims 3
- 230000008595 infiltration Effects 0.000 claims 3
- 238000001764 infiltration Methods 0.000 claims 3
- 108020004999 messenger RNA Proteins 0.000 claims 3
- 102000003839 Human Proteins Human genes 0.000 claims 2
- 108090000144 Human Proteins Proteins 0.000 claims 2
- 238000001574 biopsy Methods 0.000 claims 2
- 210000004748 cultured cell Anatomy 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 238000000370 laser capture micro-dissection Methods 0.000 claims 2
- 241000894007 species Species 0.000 claims 2
- 230000009946 DNA mutation Effects 0.000 claims 1
- 102000035195 Peptidases Human genes 0.000 claims 1
- 108091005804 Peptidases Proteins 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 239000013060 biological fluid Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 108091092328 cellular RNA Proteins 0.000 claims 1
- 230000008711 chromosomal rearrangement Effects 0.000 claims 1
- 238000012937 correction Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 238000002224 dissection Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 210000002540 macrophage Anatomy 0.000 claims 1
- 210000002200 mouth mucosa Anatomy 0.000 claims 1
- 238000013188 needle biopsy Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 238000012545 processing Methods 0.000 claims 1
- 230000000392 somatic effect Effects 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 210000003741 urothelium Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562251604P | 2015-11-05 | 2015-11-05 | |
| US62/251,604 | 2015-11-05 | ||
| PCT/US2016/028426 WO2017078787A1 (en) | 2015-11-05 | 2016-04-20 | Protein quantitation in multicellular tissue specimens |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018536175A JP2018536175A (ja) | 2018-12-06 |
| JP2018536175A5 true JP2018536175A5 (enExample) | 2019-05-30 |
| JP6742034B2 JP6742034B2 (ja) | 2020-08-19 |
Family
ID=58662934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018542117A Expired - Fee Related JP6742034B2 (ja) | 2015-11-05 | 2016-04-20 | 多細胞組織検体におけるタンパク質の定量 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11047860B2 (enExample) |
| EP (1) | EP3371605B1 (enExample) |
| JP (1) | JP6742034B2 (enExample) |
| CA (1) | CA3002962A1 (enExample) |
| WO (1) | WO2017078787A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021055894A1 (en) * | 2019-09-19 | 2021-03-25 | Janssen Biotech, Inc. | Materials and methods for differential characterization of molecular conjugates and conjugation |
| JP2023530712A (ja) * | 2020-06-18 | 2023-07-19 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 未処理ｃ末端リジンを正確に測定するための重ペプチドアプローチ |
| CN112150044B (zh) * | 2020-11-04 | 2022-04-22 | 南京大学 | 基于高分辨率质谱的污水厂含氮有机物去除效果评价方法 |
| US20240295561A1 (en) * | 2021-06-17 | 2024-09-05 | Konica Minolta, Inc. | Quantification method and labeling method |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5725481A (en) * | 1996-05-17 | 1998-03-10 | A. Fem Medical Corporation | Method and apparatus for collecting vaginal fluid and exfoliated vaginal cells for diagnostic purposes |
| WO2005061725A1 (en) * | 2003-12-23 | 2005-07-07 | Mount Sinai Hospital | Methods for detecting markers associated with endometrial disease or phase |
| US20070019854A1 (en) * | 2005-05-10 | 2007-01-25 | Bioimagene, Inc. | Method and system for automated digital image analysis of prostrate neoplasms using morphologic patterns |
| JP5240739B2 (ja) * | 2007-04-13 | 2013-07-17 | オーエスアイ・フアーマシユーテイカルズ・エル・エル・シー | キナーゼ阻害剤に対する抗癌応答を予測する生物学的マーカー |
| NZ628463A (en) * | 2009-01-14 | 2015-12-24 | Us Health | Ratio based biomarkers and methods for use thereof |
| EP2309262A1 (en) | 2009-10-06 | 2011-04-13 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Method for quantifying biomolecules |
| WO2013165598A1 (en) | 2012-04-30 | 2013-11-07 | The Research Foundation For Suny | Cancer blood test using bc200 rna isolated from peripheral blood for diagnosis and treatment of invasive breast cancer |
| KR20150090240A (ko) * | 2012-11-30 | 2015-08-05 | 어플라이드 프로테오믹스, 인크. | 결장 종양의 존재 또는 위험의 평가 방법 |
| CA2936077C (en) | 2014-01-06 | 2020-06-30 | Expression Pathology, Inc. | Srm assay for pd-l1 |
-
2016
- 2016-04-20 JP JP2018542117A patent/JP6742034B2/ja not_active Expired - Fee Related
- 2016-04-20 EP EP16862613.3A patent/EP3371605B1/en active Active
- 2016-04-20 CA CA3002962A patent/CA3002962A1/en active Pending
- 2016-04-20 WO PCT/US2016/028426 patent/WO2017078787A1/en not_active Ceased
- 2016-04-20 US US15/773,719 patent/US11047860B2/en not_active Expired - Fee Related
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